Adaptive responses by mouse fetus to a maternal HLE diet by downregulating SREBP1: A microarrayand bio-analytic-based study

Journal of Lipid Research

Volumn 54, Issue 12, 2013, Pages 3269-3280

  Yu, Huan Ling ^a   Miao, Huang Tai ^b   Gao, Li Fang ^a   Li, Li ^a   Xi, Yuan Di ^a   Nie, Shao Ping ^b   Xiao, Rong ^a  

^a CAPITAL MEDICAL UNIVERSITY   (China)

^b CAPITAL MEDICAL UNIVERSITY   (China)

Author keywords

Dietary cholesterol; Gestational diet; Highenergy high lipid diet; Maternal diet

Indexed keywords

STEROL REGULATORY ELEMENT BINDING PROTEIN 1;

ADAPTATION; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CHOLESTEROL METABOLISM; CONTROLLED STUDY; DOWN REGULATION; FATTY ACID METABOLISM; FEMALE; FETUS; GENE EXPRESSION; GENE EXPRESSION REGULATION; GENE IDENTIFICATION; GLUCOSE BLOOD LEVEL; GLUCOSE METABOLISM; INSULIN BLOOD LEVEL; LIPID BLOOD LEVEL; LIPID DIET; MALE; MATERNAL NUTRITION; METABOLIC REGULATION; MICROARRAY ANALYSIS; MOUSE; NEWBORN; NONHUMAN; PREGNANCY; PRIORITY JOURNAL; REAL TIME POLYMERASE CHAIN REACTION; SREBP1 GENE; UPREGULATION; WESTERN BLOTTING;

DIETARY CHOLESTEROL; GESTATIONAL DIET; HIGH-ENERGY HIGH-LIPID DIET; MATERNAL DIET;

ADAPTATION, PHYSIOLOGICAL; ANIMALS; CHOLESTEROL; CHOLESTEROL, DIETARY; DIET, HIGH-FAT; DOWN-REGULATION; FEMALE; FETUS; HYDROXYMETHYLGLUTARYL COA REDUCTASES; INSULIN; LIVER; MALE; MICE; MOTHERS; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PREGNANCY; RNA, MESSENGER; STEROL REGULATORY ELEMENT BINDING PROTEIN 1;

EID: 84887924969     PISSN: 00222275     EISSN: 15397262     Source Type: Journal    
DOI: 10.1194/jlr.M037416     Document Type: Article

References (33)

1. Bentham, J., A. C. Michell, H. Lockstone, D. Andrew, J. E. Schneider, N. A. Brown, and S. Bhattacharya. 2010. Maternal high-fat diet interacts with embryonic Cited2 genotype to reduce Pitx2c expression and enhance penetrance of left-right patterning defects. Hum. Mol. Genet. 19:3394-3401.
2. Rankin, J., P. W. Tennant, K. J. Stothard, M. Bythell, C. D. Summerbell, and R. Bell. 2010. Maternal body mass index and congenital anomaly risk: a cohort study. Int. J. Obes. (Lond.). 34:1371-1380.
3. Sullivan, E. L., M. S. Smith, and K. L. Grove. 2011. Perinatal exposure to high-fat diet programs energy balance, metabolism and behavior in adulthood. Neuroendocrinology. 93:1-8.
4. Takaya, J., A. Iharada, H. Okihana, and K. Kaneko. 2011. Magnesium deficiency in pregnant rats alters methylation of specific cytosines in the hepatic hydroxysteroid dehydrogenase-2 promoter of the offspring. Epigenetics. 6:573-578.
5. Theys, N., M. T. Ahn, T. Bouckenooghe, B. Reusens, and C. Remacle. 2011. Maternal malnutrition programs pancreatic islet mitochondrial dysfunction in the adult offspring. J. Nutr. Biochem. 22:985-994.
6. Rooney, K., and S. E. Ozanne. 2011. Maternal over-nutrition and offspring obesity predisposition: targets for preventative interventions. Int. J. Obes. (Lond.). 35:883-890.
7. Erhuma, A., S. McMullen, S. C. Langley-Evans, and A. J. Bennett. 2009. Feeding pregnant rats a low-protein diet alters the hepatic expression of SREBP-1c in their offspring via a glucocorticoid-related mechanism. Endocrine. 36:333-338.
8. Liang, C., M. E. Oest, and M. R. Prater. 2009. Intrauterine exposure to high saturated fat diet elevates risk of adult-onset chronic diseases in C57BL/6 mice. Birth Defects Res. B Dev. Reprod. Toxicol. 86:377-384.
9. McCurdy, C. E., J. M. Bishop, S. M. Williams, B. E. Grayson, M. S. Smith, J. E. Friedman, and K. L. Grove. 2009. Maternal high-fat diet triggers lipotoxicity in the fetal livers of nonhuman primates. J. Clin. Invest. 119:323-335.
10. Novak, E. M., E. K. Lee, S. M. Innis, and B. O. Keller. 2009. Identification of novel protein targets regulated by maternal dietary fatty acid composition in neonatal rat liver. J. Proteomics. 73:41-49.
11. Yu, H., Y. Bi, W. Ma, L. He, L. Yuan, J. Feng, and R. Xiao. 2010. Long-term effects of high lipid and high energy diet on serum lipid, brain fatty acid composition, and memory and learning ability in mice. Int. J. Dev. Neurosci. 28:271-276.
12. Wright, G. W., and R. M. Simon. 2003. A random variance model for detection of differential gene expression in small microarray experiments. Bioinformatics. 19:2448-2455. (Pubitemid 38016644)
13. Yang, H., N. Crawford, L. Lukes, R. Finney, M. Lancaster, and K. W. Hunter. 2005. Metastasis predictive signature profiles pre-exist in normal tissues. Clin. Exp. Metastasis. 22:593-603. (Pubitemid 43234644)
14. Clarke, R., H. W. Ressom, A. Wang, J. Xuan, M. C. Liu, E. A. Gehan, and Y. Wang. 2008. The properties of high-dimensional data spaces: implications for exploring gene and protein expression data. Nat. Rev. Cancer. 8:37-49.
15. Yi, M., J. D. Horton, J. C. Cohen, H. H. Hobbs, and R. M. Stephens. 2006. WholePathwayScope: a comprehensive pathway-based analysis tool for high-throughput data. BMC Bioinformatics. 7:30.
16. Ashburner, M., C. A. Ball, J. A. Blake, D. Botstein, H. Butler, J. M. Cherry, A. P. Davis, K. Dolinski, S. S. Dwight, J. T. Eppig, et al. 2000. Gene ontology: tool for the unification of biology. The Gene Ontology Consortium. Nat. Genet. 25:25-29. (Pubitemid 30257031)
17. Schlitt, T., K. Palin, J. Rung, S. Dietmann, M. Lappe, E. Ukkonen, and A. Brazma. 2003. From gene networks to gene function. Genome Res. 13:2568-2576. (Pubitemid 37541145)
18. Kanehisa, M., S. Goto, S. Kawashima, Y. Okuno, and M. Hattori. 2004. The KEGG resource for deciphering the genome. Nucleic Acids Res. 32:D277 - D280. (Pubitemid 38081656)
19. Draghici, S., P. Khatri, A. L. Tarca, K. Amin, A. Done, C. Voichita, C. Georgescu, and R. Romero. 2007. A systems biology approach for pathway level analysis. Genome Res. 17:1537-1545. (Pubitemid 47529438)
20. Ravasz, E., A. L. Somera, D. A. Mongru, Z. N. Oltvai, and A. L. Barabasi. 2002. Hierarchical organization of modularity in metabolic networks. Science. 297:1551-1555. (Pubitemid 34971002)
21. Carlson, M. R., B. Zhang, Z. Fang, P. S. Mischel, S. Horvath, and S. F. Nelson. 2006. Gene connectivity, function, and sequence conservation: predictions from modular yeast co-expression networks. BMC Genomics. 7:40.
22. Liu, S., K. Bertl, H. Sun, Z. H. Liu, O. Andrukhov, and X. Rausch-Fan. 2012. Effect of simvastatin on the osteogenetic behavior of alveolar osteoblasts and periodontal ligament cells. Hum. Cell. 25:29-35.
23. Folch, J., M. Lees, and G. H. Sloane Stanley. 1957. A simple method for the isolation and purification of total lipides from animal tissues. J. Biol. Chem. 226:497-509.
24. Franco, J. G., T. P. Fernandes, C. P. Rocha, C. Calvino, C. C. Pazos-Moura, P. C. Lisboa, E. G. Moura, and I. H. Trevenzoli. 2012. Maternal high-fat diet induces obesity and adrenal and thyroid dysfunction in male rat offspring at weaning. J. Physiol. 590:5503-5518.
25. Armitage, J. A., P. D. Taylor, and L. Poston. 2005. Experimental models of developmental programming: consequences of exposure to an energy rich diet during development. J. Physiol. 565:3-8. (Pubitemid 40723685)
26. Srinivasan, M., S. D. Katewa, A. Palaniyappan, J. D. Pandya, and M. S. Patel. 2006. Maternal high-fat diet consumption results in fetal malprogramming predisposing to the onset of metabolic syndrome-like phenotype in adulthood. Am. J. Physiol. Endocrinol. Metab. 291:E792 - E799. (Pubitemid 44484922)
27. Shankar, K., P. Kang, A. Harrell, Y. Zhong, J. C. Marecki, M. J. Ronis, and T. M. Badger. 2010. Maternal overweight programs insulin and adiponectin signaling in the offspring. Endocrinology. 151:2577-2589.
28. Borengasser, S. J., F. Lau, P. Kang, M. L. Blackburn, M. J. Ronis, T. M. Badger, and K. Shankar. 2011. Maternal obesity during gestation impairs fatty acid oxidation and mitochondrial SIRT3 expression in rat offspring at weaning. PLoS ONE. 6:e24068.
29. Goharkhay, N., E. H. Tamayo, H. Yin, G. D. Hankins, G. R. Saade, and M. Longo. 2008. Maternal hypercholesterolemia leads to activation of endogenous cholesterol synthesis in the offspring. Am. J. Obstet. Gynecol. 199:273.e1-273.e6.
30. Volpato, A. M., A. Schultz, E. Magalhaes-da-Costa, M. L. Correia, M. B. Aguila, and C. A. Mandarim-de-Lacerda. 2012. Maternal high-fat diet programs for metabolic disturbances in offspring despite leptin sensitivity. Neuroendocrinology. 96:272-284.
31. Horton, J. D., J. L. Goldstein, and M. S. Brown. 2002. SREBPs: activators of the complete program of cholesterol and fatty acid synthesis in the liver. J. Clin. Invest. 109:1125-1131. (Pubitemid 34496588)
32. Wang, H., G. Kouri, and C. B. Wollheim. 2005. ER stress and SREBP-1 activation are implicated in beta-cell glucolipotoxicity. J. Cell Sci. 118:3905-3915. (Pubitemid 41410274)
33. Li, J., J. Huang, J. S. Li, H. Chen, K. Huang, and L. Zheng. 2012. Accumulation of endoplasmic reticulum stress and lipogenesis in the liver through generational effects of high fat diets. J. Hepatol. 56:900-907.