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Volumn 18, Issue 6, 2013, Pages 489-500

The pharmacokinetics and pharmacodynamics of dehydroepiandrosterone during use of an ethinylestradiol-and drospirenone-containing oral contraceptive

Author keywords

Androgens; DHEA; DHEA S; Oral contraception; Pharmacokinetics; Testosterone

Indexed keywords

ALBUMIN; DROSPIRENONE; ESTRADIOL; ETHINYLESTRADIOL; ORAL CONTRACEPTIVE AGENT; PRASTERONE; PRASTERONE SULFATE; SULFATE; TESTOSTERONE;

EID: 84887913015     PISSN: 13625187     EISSN: 14730782     Source Type: Journal    
DOI: 10.3109/13625187.2013.822061     Document Type: Article
Times cited : (3)

References (41)
  • 1
    • 0017839761 scopus 로고
    • Effect of oral contraceptives on plasma androgenic steroids and their precursors
    • Fern M, Rose D, Fern E. Effect of oral contraceptives on plasma androgenic steroids and their precursors. Obstet Gynecol 1978; 51: 541-4.
    • (1978) Obstet Gynecol , vol.51 , pp. 541-544
    • Fern, M.1    Rose, D.2    Fern, E.3
  • 2
    • 0032144535 scopus 로고    scopus 로고
    • A randomized crossover study on various hormonal parameters of two tripha-sic oral contraceptives
    • Aden U, Jung-Hoffmann C, Kuhl H. A randomized crossover study on various hormonal parameters of two tripha-sic oral contraceptives. Contraception 1998; 58: 75-81.
    • (1998) Contraception , vol.58 , pp. 75-81
    • Aden, U.1    Jung-Hoffmann, C.2    Kuhl, H.3
  • 3
    • 0037232892 scopus 로고    scopus 로고
    • Effect of four different oral contraceptives on various sex hormones and serum-binding globulins
    • Wiegratz I, Kutschera E, Lee J, et al. Effect of four different oral contraceptives on various sex hormones and serum-binding globulins. Contraception 2003; 67: 25-32.
    • (2003) Contraception , vol.67 , pp. 25-32
    • Wiegratz, I.1    Kutschera, E.2    Lee, J.3
  • 4
    • 80955130105 scopus 로고    scopus 로고
    • Effects of a monophasic combined oral contraceptive containing nomegestrol acetate and 17 ß-oestradiol in comparison to one containing levonorgestrel and ethinylestradiol on markers of endocrine function
    • Ågren UM, Anttila M, Mäepää-Liukko K, et al. Effects of a monophasic combined oral contraceptive containing nomegestrol acetate and 17 ß-oestradiol in comparison to one containing levonorgestrel and ethinylestradiol on markers of endocrine function. Eur J Contracept Reprod Health Care 2011; 16: 458-67.
    • (2011) Eur J Contracept Reprod Health Care , vol.16 , pp. 458-467
    • Ågren, U.M.1    Anttila, M.2    Mäepää-Liukko, K.3
  • 5
    • 0025246101 scopus 로고
    • Effects of seven low-dose combined oral contraceptives on sex hormone binding globulin, corticosteroid binding globulin, total and free testosterone
    • Van der Vange N, Blankenstein M, Kloosterboer H, et al. Effects of seven low-dose combined oral contraceptives on sex hormone binding globulin, corticosteroid binding globulin, total and free testosterone. Contraception 1990; 41: 345-52.
    • (1990) Contraception , vol.41 , pp. 345-352
    • Van Der Vange, N.1    Blankenstein, M.2    Kloosterboer, H.3
  • 6
    • 0029930874 scopus 로고    scopus 로고
    • Changes in andro-gens during treatment with four low-dose contraceptives
    • Coenen C, Thomas C, Borm G, et al. Changes in andro-gens during treatment with four low-dose contraceptives. Contraception 1996; 53: 171-6.
    • (1996) Contraception , vol.53 , pp. 171-176
    • Coenen, C.1    Thomas, C.2    Borm, G.3
  • 7
    • 34250757980 scopus 로고    scopus 로고
    • The effects of oral contraceptives on androgen levels and their relevance to premenstrual mood and sexual interest: A comparison of two triphasic formulations containing norgestimate and either 35 or 25 μ g of ethinyl estradiol
    • Greco T, Graham C, Bancroft J, et al. The effects of oral contraceptives on androgen levels and their relevance to premenstrual mood and sexual interest: A comparison of two triphasic formulations containing norgestimate and either 35 or 25 μ g of ethinyl estradiol. Contraception 2007; 76: 8-17.
    • (2007) Contraception , vol.76 , pp. 8-17
    • Greco, T.1    Graham, C.2    Bancroft, J.3
  • 8
    • 0036009792 scopus 로고    scopus 로고
    • Female androgen insufficiency: The Princeton consensus statement on definition, classification, and assessment
    • Bachmann G, Bancroft J, Braunstein G, et al. Female androgen insufficiency: The Princeton consensus statement on definition, classification, and assessment. Fertil Steril 2002; 77: 660-5.
    • (2002) Fertil Steril , vol.77 , pp. 660-665
    • Bachmann, G.1    Bancroft, J.2    Braunstein, G.3
  • 9
    • 34548324673 scopus 로고    scopus 로고
    • The Testosterone Therapy in Women Study Group. Are the Endocrine Society's clinical practice guidelines on androgen therapy in women misguided? A commentary
    • Traish A, Guay A, Spark R, the Testosterone Therapy in Women Study Group. Are the Endocrine Society's clinical practice guidelines on androgen therapy in women misguided? A commentary. J Sex Med 2007; 4: 1223-35.
    • (2007) J Sex Med , vol.4 , pp. 1223-1235
    • Traish, A.1    Guay, A.2    Spark, R.3
  • 10
    • 0031732821 scopus 로고    scopus 로고
    • Oral dehydroepiandros-terone for adrenal androgen replacement: Pharmacoki-netics and peripheral conversion to androgens and estrogens in young healthy females after dexamethasone suppression
    • Arlt W, Justl H-G, Callies F, et al. Oral dehydroepiandros-terone for adrenal androgen replacement: Pharmacoki-netics and peripheral conversion to androgens and estrogens in young healthy females after dexamethasone suppression. J Clin Endocrinol Metab 1998; 83: 1928-34.
    • (1998) J Clin Endocrinol Metab , vol.83 , pp. 1928-1934
    • Arlt, W.1    Justl, H.-G.2    Callies, F.3
  • 11
    • 0028221213 scopus 로고
    • Effects of replacement dose of dehydroepiandrosterone in men and women of advancing age
    • Morales A, Nolan J, Nelson J, Yen S. Effects of replacement dose of dehydroepiandrosterone in men and women of advancing age. J Clin Endocrinol Metab 1994; 78: 1360-7.
    • (1994) J Clin Endocrinol Metab , vol.78 , pp. 1360-1367
    • Morales, A.1    Nolan, J.2    Nelson, J.3    Yen, S.4
  • 12
    • 0033694517 scopus 로고    scopus 로고
    • Dehydroepian-drosterone replacement administration: Pharmacoki-netic and pharmacodynamic studies in healthy elderly subjects
    • Legrain S, Massien C, Lahlou N, et al. Dehydroepian-drosterone replacement administration: Pharmacoki-netic and pharmacodynamic studies in healthy elderly subjects. J Clin Endocrinol Metab 2000; 85: 3208-17.
    • (2000) J Clin Endocrinol Metab , vol.85 , pp. 3208-3217
    • Legrain, S.1    Massien, C.2    Lahlou, N.3
  • 13
    • 0034770184 scopus 로고    scopus 로고
    • Effects of oral prasterone (dehydroepiandrosterone) on single-dose pharmacokinetics or oral prednisone and cortisol suppression in normal women
    • Meno-Tetang G, Blum R, Schwartz K, Jusko W. Effects of oral prasterone (dehydroepiandrosterone) on single-dose pharmacokinetics or oral prednisone and cortisol suppression in normal women. J Clin Pharmacol 2001; 41: 1195-205.
    • (2001) J Clin Pharmacol , vol.41 , pp. 1195-1205
    • Meno-Tetang, G.1    Blum, R.2    Schwartz, K.3    Jusko, W.4
  • 14
    • 84877823286 scopus 로고    scopus 로고
    • The bioequivalence of the contraceptive steroids ethinylestradiol and drospirenone is not affected by co-administration of DHEA
    • Zimmerman Y, Wouters W, Coelingh Bennink HJT. The bioequivalence of the contraceptive steroids ethinylestradiol and drospirenone is not affected by co-administration of DHEA. Eur J Contracept Reprod Health Care 2013; 18: 206-14.
    • (2013) Eur J Contracept Reprod Health Care , vol.18 , pp. 206-214
    • Zimmerman, Y.1    Wouters, W.2    Coelingh Bennink, H.J.T.3
  • 15
    • 0033305020 scopus 로고    scopus 로고
    • A critical evaluation of simple methods for the estimation of free testosterone in serum
    • Vermeulen A, Verdonck L, Kaufman JM. A critical evaluation of simple methods for the estimation of free testosterone in serum. J Clin Endocrinol Metab 1999; 84: 3666-72.
    • (1999) J Clin Endocrinol Metab , vol.84 , pp. 3666-3672
    • Vermeulen, A.1    Verdonck, L.2    Kaufman, J.M.3
  • 16
    • 33748304146 scopus 로고    scopus 로고
    • Calculation of bioavailable and free testosterone in men: A comparison of 5 published algorithms
    • de Ronde W, van der Schouw YT, Pols HAP, et al. Calculation of bioavailable and free testosterone in men: A comparison of 5 published algorithms. Clin Chem 2006; 52: 1777-84.
    • (2006) Clin Chem , vol.52 , pp. 1777-1784
    • De Ronde, W.1    Van Der Schouw, Y.T.2    Hap, P.3
  • 17
    • 0036800654 scopus 로고    scopus 로고
    • Validity of free testosterone and free estradiol determinations in serum samples from postmenopausal women by theoretical calculations
    • Rinaldi S, Geay A, Déchaud H, et al. Validity of free testosterone and free estradiol determinations in serum samples from postmenopausal women by theoretical calculations. Cancer Epidemiol Biomarkers Prev 2002; 11: 1065-71.
    • (2002) Cancer Epidemiol Biomarkers Prev , vol.11 , pp. 1065-1071
    • Rinaldi, S.1    Geay, A.2    Déchaud, H.3
  • 18
    • 1442327861 scopus 로고    scopus 로고
    • Measurement of free testosterone in normal women and women with androgen deficiency: Compar ison of methods
    • Miller KK, Rosner W, Lee H, et al. Measurement of free testosterone in normal women and women with androgen deficiency: Compar ison of methods. J Clin Endocrinol Metab 2004; 89: 525-33.
    • (2004) J Clin Endocrinol Metab , vol.89 , pp. 525-533
    • Miller, K.K.1    Rosner, W.2    Lee, H.3
  • 19
    • 0032508981 scopus 로고    scopus 로고
    • Quality control of dehydroepiandrosterone dietary supplement products
    • Parasrampuria J, Schwartz K, Petesch R. Quality control of dehydroepiandrosterone dietary supplement products. JAMA 1998; 280: 1565.
    • (1998) JAMA , vol.280 , pp. 1565
    • Parasrampuria, J.1    Schwartz, K.2    Petesch, R.3
  • 20
    • 12944305796 scopus 로고    scopus 로고
    • Dehydroepian-drosterone (DHEA), DHEA sulfate, and aging: Contribution of the DHEAge Study to a sociobiomedical issue
    • Baulieu E-E, Thomas G, Legrain S, et al. Dehydroepian-drosterone (DHEA), DHEA sulfate, and aging: Contribution of the DHEAge Study to a sociobiomedical issue. PNAS 2000; 97: 4279-84.
    • (2000) PNAS , vol.97 , pp. 4279-4284
    • Baulieu, E.-E.1    Thomas, G.2    Legrain, S.3
  • 21
    • 0036280119 scopus 로고    scopus 로고
    • Can changes in sex hormone binding globulin predict the risk of venous thromboembolism with combined oral contraceptive pills?
    • Odlind V, Milson I, Persson I, Victor A. Can changes in sex hormone binding globulin predict the risk of venous thromboembolism with combined oral contraceptive pills? Acta Obstet Gynecol Scand 2002; 81: 482-90.
    • (2002) Acta Obstet Gynecol Scand , vol.81 , pp. 482-490
    • Odlind, V.1    Milson, I.2    Persson, I.3    Victor, A.4
  • 22
    • 0036397299 scopus 로고    scopus 로고
    • Diurnal rhythm and effects of oral contraceptives on serum dehydroepiandrosterone sulfate (DHEAS) are related to alterations in serum albumin rather than to changes in adrenocortical steroid secretion
    • Carlström K, Karlsson R, Von Schoultz B. Diurnal rhythm and effects of oral contraceptives on serum dehydroepiandrosterone sulfate (DHEAS) are related to alterations in serum albumin rather than to changes in adrenocortical steroid secretion. Scand J Clin Lab Invest 2002; 62: 361-8.
    • (2002) Scand J Clin Lab Invest , vol.62 , pp. 361-368
    • Carlström, K.1    Karlsson, R.2    Von Schoultz, B.3
  • 23
    • 4444301683 scopus 로고    scopus 로고
    • The diurnal patterns of the adrenal steroids cortisol and dehydroepiandrosterone (DHEA) in relation to awakening
    • Hucklebridge F, Hussain T, Evans P, Clow A. The diurnal patterns of the adrenal steroids cortisol and dehydroepiandrosterone (DHEA) in relation to awakening. Psychoneuroendocrinology 2005; 30: 51-7.
    • (2005) Psychoneuroendocrinology , vol.30 , pp. 51-57
    • Hucklebridge, F.1    Hussain, T.2    Evans, P.3    Clow, A.4
  • 24
    • 36249010961 scopus 로고    scopus 로고
    • Diurnal and seasonal cortisol, testosterone, and DHEA rhythms in boys and girls dur ing puberty
    • Matchock RL, Dorn LD, Susman EJ. Diurnal and seasonal cortisol, testosterone, and DHEA rhythms in boys and girls dur ing puberty. Chronobiol Int 2007; 24: 969-90.
    • (2007) Chronobiol Int , vol.24 , pp. 969-990
    • Matchock, R.L.1    Dorn, L.D.2    Susman, E.J.3
  • 25
    • 0018186575 scopus 로고
    • The effect of oral contraceptive treatment on the serum concentration of dehydroisoandrosterone sulfate
    • Madden JD, Milewich L, Parker CR Jr., et al. The effect of oral contraceptive treatment on the serum concentration of dehydroisoandrosterone sulfate. Am J Obstet Gynecol 1978; 132: 380-4.
    • (1978) Am J Obstet Gynecol , vol.132 , pp. 380-384
    • Madden, J.D.1    Milewich, L.2    Parker Jr., C.R.3
  • 26
    • 0022143244 scopus 로고
    • Circadian and circannual variations on FSH, LH, testosterone, dehy-droepiandrosterone-sulfate (DHEA-S) and 17-hydroxy progesterone (17 OH-Prog) in elderly men and women
    • Nicolau GY, Haus E, Lakatua DJ, et al. Circadian and circannual variations on FSH, LH, testosterone, dehy-droepiandrosterone-sulfate (DHEA-S) and 17-hydroxy progesterone (17 OH-Prog) in elderly men and women. Endocrinologie 1985; 23: 223-46.
    • (1985) Endocrinologie , vol.23 , pp. 223-246
    • Nicolau, G.Y.1    Haus, E.2    Lakatua, D.J.3
  • 27
    • 0029279538 scopus 로고
    • Daily variation of serum cortisol, 17-hydroxyprogesterone and five androgens in healthy women
    • Mikulecky M, Kreze A, Putz Z, Moravcik M. Daily variation of serum cortisol, 17-hydroxyprogesterone and five androgens in healthy women. Braz J Med Biol Res 1995; 28: 485-90.
    • (1995) Braz J Med Biol Res , vol.28 , pp. 485-490
    • Mikulecky, M.1    Kreze, A.2    Putz, Z.3    Moravcik, M.4
  • 28
    • 21244462808 scopus 로고    scopus 로고
    • No evidence for hepatic conversion of dehydroepiandrosterone (DHEA) sulfate to DHEA: In vivo and in vitro studies
    • Hammer F, Subtil S, Lux P, et al. No evidence for hepatic conversion of dehydroepiandrosterone (DHEA) sulfate to DHEA: In vivo and in vitro studies. J Clin Endocrinol Metab 2005; 90: 3600-5.
    • (2005) J Clin Endocrinol Metab , vol.90 , pp. 3600-3605
    • Hammer, F.1    Subtil, S.2    Lux, P.3
  • 29
    • 0025176686 scopus 로고
    • Effect of low-dose oral contraceptive on gonadotropins, androgens, and sex hormone binding globulin in nonhirsute women
    • Murphy AA, Cropp CS, Smith BS, et al. Effect of low-dose oral contraceptive on gonadotropins, androgens, and sex hormone binding globulin in nonhirsute women. Fertil Steril 1990; 53: 35-9.
    • (1990) Fertil Steril , vol.53 , pp. 35-39
    • Murphy, A.A.1    Cropp, C.S.2    Smith, B.S.3
  • 30
    • 0029001359 scopus 로고
    • Effect of two oral contraceptives containing ethinylestradiol and gestodene or norgestimate upon androgen parameters and ser um binding proteins
    • Wiegratz I, Jung-Hoffmann C, Kuhl H. Effect of two oral contraceptives containing ethinylestradiol and gestodene or norgestimate upon androgen parameters and ser um binding proteins. Contraception 1995; 51: 341-6.
    • (1995) Contraception , vol.51 , pp. 341-346
    • Wiegratz, I.1    Jung-Hoffmann, C.2    Kuhl, H.3
  • 31
    • 0018616352 scopus 로고
    • Plasma levels of adrenocorticotropin and cortisol in women receiving oral contraceptive steroid treatment
    • Carr BR, Parker CR Jr., Madden JD, et al. Plasma levels of adrenocorticotropin and cortisol in women receiving oral contraceptive steroid treatment. J Clin Endocrinol Metab 1979; 49: 346-9.
    • (1979) J Clin Endocrinol Metab , vol.49 , pp. 346-349
    • Carr, B.R.1    Parker Jr., C.R.2    Madden, J.D.3
  • 32
    • 0021136392 scopus 로고
    • The effect of different contraceptive treatments on the serum concentration of dehydroepiandrosterone sulfate
    • Klove KL, Roy S, Lobo RA. The effect of different contraceptive treatments on the serum concentration of dehydroepiandrosterone sulfate. Contraception 1984; 29: 319-24.
    • (1984) Contraception , vol.29 , pp. 319-324
    • Klove, K.L.1    Roy, S.2    Lobo, R.A.3
  • 33
    • 0027318381 scopus 로고
    • An open-label dose-escalation trial of oral dehydroepiandrosterone tolerance and pharmacokinetics in patients with HIV disease
    • Dyner TS, Lang W, Geaga J, et al. An open-label dose-escalation trial of oral dehydroepiandrosterone tolerance and pharmacokinetics in patients with HIV disease. J Acquir Immune Defic Syndr 1993; 6: 459-65.
    • (1993) J Acquir Immune Defic Syndr , vol.6 , pp. 459-465
    • Dyner, T.S.1    Lang, W.2    Geaga, J.3
  • 34
    • 77957309020 scopus 로고    scopus 로고
    • Effects of a monophasic combined oral contraceptive containing nomegestrol acetate and 17 ß-oestradiol on ovarian function in comparison to a monophasic combined oral contraceptive containing drospirenone and ethinylestradiol
    • Duijkers I, Klipping C, Grob P, Korver T. Effects of a monophasic combined oral contraceptive containing nomegestrol acetate and 17 ß-oestradiol on ovarian function in comparison to a monophasic combined oral contraceptive containing drospirenone and ethinylestradiol. Eur J Contracept Reprod Health Care 2010; 15: 314-25.
    • (2010) Eur J Contracept Reprod Health Care , vol.15 , pp. 314-325
    • Duijkers, I.1    Klipping, C.2    Grob, P.3    Korver, T.4
  • 35
    • 0034473223 scopus 로고    scopus 로고
    • A 1-year pharma-cokinetic investigation of a novel oral contraceptive containing drospirenone in healthy female volunteers
    • Blode H, Wuttke W, Loock W, et al. A 1-year pharma-cokinetic investigation of a novel oral contraceptive containing drospirenone in healthy female volunteers. Eur J Contracept Reprod Health Care 2000; 5: 256-64.
    • (2000) Eur J Contracept Reprod Health Care , vol.5 , pp. 256-264
    • Blode, H.1    Wuttke, W.2    Loock, W.3
  • 36
    • 84887885922 scopus 로고    scopus 로고
    • Clinical effects of normalizing testosterone levels during oral contraception
    • Zimmerman Y, Coelingh Bennink HJT. Clinical effects of normalizing testosterone levels during oral contraception. Ferti Steril 2012; 98(3, Suppl.): S198.
    • (2012) Ferti Steril , vol.98 , Issue.3 SUPPL.
    • Zimmerman, Y.1    Coelingh Bennink, H.J.T.2
  • 37
    • 0025605846 scopus 로고
    • Gonadotropin and estradiol secretion during the week of placebo therapy in oral contraceptive pill users
    • van der Spuy ZM, Sohnius U, Pienaar CA, Schall R. Gonadotropin and estradiol secretion during the week of placebo therapy in oral contraceptive pill users. Contraception 1990; 42: 597-609.
    • (1990) Contraception , vol.42 , pp. 597-609
    • Van Der Spuy, Z.M.1    Sohnius, U.2    Pienaar, C.A.3    Schall, R.4
  • 38
    • 33750049989 scopus 로고    scopus 로고
    • DHEA in elderly women and DHEA or testosterone in elderly men
    • Nair KS, Rizza RA, O'Brien P, et al. DHEA in elderly women and DHEA or testosterone in elderly men. N Engl J Med 2006; 355: 1647-59.
    • (2006) N Engl J Med , vol.355 , pp. 1647-1659
    • Nair, K.S.1    Rizza, R.A.2    O'Brien, P.3
  • 39
    • 65549143117 scopus 로고    scopus 로고
    • Dehydroepiandros-terone replacement therapy in older adults: 1-and 2-y effects on bone
    • Weiss EP, Shah K, Fontana L, et al. Dehydroepiandros-terone replacement therapy in older adults: 1-and 2-y effects on bone. Am J Clin Nutr 2009; 89: 1459-67.
    • (2009) Am J Clin Nutr , vol.89 , pp. 1459-1467
    • Weiss, E.P.1    Shah, K.2    Fontana, L.3
  • 40
    • 70349921326 scopus 로고    scopus 로고
    • A systematic review and meta-analysis of randomized placebo-controlled trials of DHEA treatment effects on quality of life in women with adrenal insufficiency
    • Alkatib AA, Cosma M, Elamin MB, et al. A systematic review and meta-analysis of randomized placebo-controlled trials of DHEA treatment effects on quality of life in women with adrenal insufficiency. J Clin Endocrinol Metab 2009; 94: 3676-81.
    • (2009) J Clin Endocrinol Metab , vol.94 , pp. 3676-3681
    • Alkatib, A.A.1    Cosma, M.2    Elamin, M.B.3


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