Multiple KRAS mutations in pancreatic adenocarcinoma: Molecular features of neoplastic clones indicate the selection of divergent populations of tumor cells

International Journal of Surgical Pathology

Volumn 21, Issue 6, 2013, Pages 546-552

  Visani, Michela ^a   De Biase, Dario ^a   Baccarini, Paola ^a   Fabbri, Carlo ^b   Polifemo, Anna Maria ^b   Zanini, Nicola ^c   Pession, Annalisa ^a   Tallini, Giovanni ^a  

^a UNIVERSITY OF BOLOGNA   (Italy)

^b BELLARIA HOSPITAL   (Italy)

^c MAGGIORE HOSPITAL   (Italy)

Author keywords

EUS FNA; KRAS mutation; multiple mutations; next generation sequencing; pancreatic adenocarcinoma

Indexed keywords

DNA; K RAS PROTEIN; NUCLEIC ACID; ONCOPROTEIN;

AGED; ALLELE; ARTICLE; CANCER PALLIATIVE THERAPY; CASE REPORT; CLONE; COMPUTER ASSISTED TOMOGRAPHY; DEATH; DNA REPAIR; ENDOSCOPE; ENDOSCOPIC ECHOGRAPHY; ENDOSCOPIC RETROGRADE CHOLANGIOPANCREATOGRAPHY; FEMALE; FINE BIOPSY NEEDLE; FINE NEEDLE ASPIRATION BIOPSY; GENE MUTATION; GENE SEQUENCE; GERIATRIC PATIENT; HUMAN; MISMATCH REPAIR; MULTIPLE MUTATION; NEXT GENERATION SEQUENCING; NUCLEIC ACID ANALYSIS; ONCOGENE K RAS; PANCREAS ADENOCARCINOMA; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; TUMOR CELL; ULTRASOUND;

EUS-FNA; KRAS MUTATION; MULTIPLE MUTATIONS; NEXT-GENERATION SEQUENCING; PANCREATIC ADENOCARCINOMA;

ADENOCARCINOMA; AGED, 80 AND OVER; CLONE CELLS; DNA MUTATIONAL ANALYSIS; FEMALE; HUMANS; MUTATION; PANCREATIC NEOPLASMS; PROTO-ONCOGENE PROTEINS; RAS PROTEINS;

EID: 84887900833     PISSN: 10668969     EISSN: 19402465     Source Type: Journal    
DOI: 10.1177/1066896912475073     Document Type: Article

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