Role of hippocampal neurogenesis in mnemonic segregation: Implications for human mood disorders

World Journal of Biological Psychiatry

Volumn 14, Issue 8, 2013, Pages 602-610

  Perera, Tarique D ^a   Thirumangalakudi, Lakshmi ^a   Glennon, Erin ^a   Park, Sungshic ^a   Insanally, Michele ^a   Persky, Michael ^a   Fonseka, Janaki ^a   Dwork, Andrew J ^a,b   Sackeim, Harold A ^a   Coplan, Jeremy D ^a,c   Fenton, André A ^c,d  

^a NEW YORK STATE PSYCHIATRIC INSTITUTE   (United States)

^b NY ^*  (United States)

^c SUNY DOWNSTATE MEDICAL CENTER   (United States)

^d NEW YORK UNIVERSITY   (United States)

Author keywords

Cognition; Depression; Hippocampus; Neurogenesis; Rats

Indexed keywords

FLUOXETINE; PLACEBO; VENLAFAXINE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AVOIDANCE BEHAVIOR; COGNITION; CONTROLLED STUDY; DEPRESSION; HIPPOCAMPUS; LEARNING; LEARNING DISORDER; MALE; MEMORY; MOOD; MOOD DISORDER; NERVE CELL; NERVOUS SYSTEM DEVELOPMENT; NONHUMAN; RAT; STRESS; SYNAPTIC POTENTIAL;

ANIMALS; ANTIDEPRESSIVE AGENTS, SECOND-GENERATION; BEHAVIOR, ANIMAL; CYCLOHEXANOLS; HIPPOCAMPUS; MALE; MEMORY; MOOD DISORDERS; NEUROGENESIS; NEURONS; PLACEBOS; PSYCHOMOTOR PERFORMANCE; RATS; RATS, LONG-EVANS; STRESS, PSYCHOLOGICAL;

EID: 84887867466     PISSN: 15622975     EISSN: 18141412     Source Type: Journal    
DOI: 10.3109/15622975.2013.768356     Document Type: Article

References (43)

1. Abdel Baki S., Kao H, Kelemen E., Fenton A, Bergold P. 2009. A hierarchy of neurobehavioral tasks discriminates between mild and moderate brain injury in rats. Brain Res 1280: 98-106.
2. Airan RD, Meltzer LA, Roy M, Gong Y., Chen H, Deisseroth K. 2007. High-speed imaging reveals neurophysiological links to behavior in an animal model of depression. Science 317(5839): 819-23. (Pubitemid 47257922)
3. Brown JP, Couillard-Despres S, Cooper-Kuhn CM, Winkler J, Aigner L., Kuhn HG. 2003. Transient expression of doublecortin during adult neurogenesis. J Comp Neurol 467(1): 1-10. (Pubitemid 37339753)
4. Burghardt NS, Park EH, Hen R, Fenton AA. 2012. Adult-born hippocampal neurons promote cognitive flexibility in mice. H ippocampus. 9: 1795-808.
5. Cimadevilla JM, Fenton AA, Bures J. 2000. Functional inactivation of dorsal hippocampus impairs active place avoidance in rats. Neurosci Lett 285: 53-56. (Pubitemid 30224622)
6. Cimadevilla JM, Wesierska M, Fenton A.A., Bures J. 2001. Inactivating one hippocampus impairs avoidance of a stable room-defined place during dissociation of arena cues from room cues by rotation of the arena. Proc Natl Acad Sci USA 98: 3531-3536. (Pubitemid 32220879)
7. Clelland CD, Choi M, Romberg C., Clemenson GD Jr, Fragniere A, Tyers P, et al. 2009. A functional role for adult hippocampal neurogenesis in spatial pattern separation. Science 325: 210-213.
8. Deng W, Aimone JB, Gage FH. 2010. New neurons and new memories: how does adult hippocampal neurogenesis affect learning and memory? Nature 11: 339-350.
9. Duman RS, Malberg J, Thome J. 1999. Neural plasticity to stress and antidepressant treatment. Biol Psychiatry 46: 1181-1191. (Pubitemid 30114436)
10. Gould E, Reeves AJ, Fallah M, Tanapat P., Gross CG, Fuchs E. 1999. Hippocampal neurogenesis in adult Old World primates. Proc Natl Acad Sci USA 96: 5263-5267. (Pubitemid 29214571)
11. Herdegen T, Kovar y K, Buhl A, Bravo R., Zimmermann M, Grass P. 1995. Basal expression of the inducible transcription factors c-Jun, JunB, JunD, c-Fos and Krox-24 in the adult rat brain. J Comp Neurol 354: 39-56.
12. Holick KA, Lee DC, Hen R, Dulawa SC. 2008. Behavioral effects of chronic fluoxetine in BALB/cJ mice do not require adult hippocampal neurogenesis or the serotonin 1A receptor. Neuropsychopharmacology 33(2): 406-417. (Pubitemid 350243341)
13. Kelemen E, Fenton AA. 2008. What do place cells tell us about learning to associate and learning to segregate? In: Mizumori S, editor. Hippocampal place fields: Relevance to learning and memory. New York: Oxford University Press. p. 127-137.
14. Kelemen E, Fenton AA. 2010. Dynamic grouping of hippocampal neural activity during cognitive control of two spatial frames. PLoS Biol 8(6): e1000403.
15. Kubik S, Fenton AA. 2005. Behavioral evidence that segregation and representation are dissociable hippocampal functions. J Neurosci 25(40): 9205-9212. (Pubitemid 41500829)
16. Lacefield CO, Itskov V, Reardon T., Hen R, Gordon JA. 2010. Effects of adult-generated granule cells on coordinated network activity in the dentate gyrus. Hippocampus: n/a-n/a.
17. Leuner B, Mendolia-Loffredo S, Shors TJ. 2004. Males and females respond differently to controllability and antidepressant treatment. Biol Psychiatry 56: 964-970. (Pubitemid 39643055)
18. Leutgeb JK, Leutgeb S, Moser M.B., Moser EI. 2007. Pattern separation in the dentate gyrus and CA3 of the hippocampus. Science 315(5814): 961-966. (Pubitemid 46281178)
19. Ling DS, Benardo LS, Serrano P.A., Blace N., Kelly MT, Crary JF, Sacktor TC. 2002. Protein kinase Mzeta is necessary and sufficient for LTP maintenance. Nat Neurosci 5: 295-296. (Pubitemid 34279806)
20. Marr D. 1971. Simple memory: a theory for archicortex. Phil Trans R Soc London B Biol Sci 262: 23-81.
21. McHugh TJ, Jones MW, Quinn J.J., Balthasar N., Coppari R, Elmquist JK, et al. 2007. Dentate gyrus NMDA receptors mediate rapid pattern separation in the hippocampal network. Science 317: 94-99. (Pubitemid 47056461)
22. Meshi D, Drew MR, Saxe M, Ansorge M.S., David D., Santarelli L, et al. 2006. Hippocampal neurogenesis is not required for behavioral effects of environmental enrichment. Nat Neurosci 9(6): 729-731.
23. Miller MW, Nowakowski RS. 1988. Use of bromodeoxyuridine- immunohistochemistry to examine the proliferation, migration and time of origin of cells in the central nervous system. Brain Res 457(1): 44-52.
24. Morinobu S, Nibuya M, Duman RS. 1995. Chronic antidepressant treatment down-regulates induction of c-fos mRNA in response to acute stress in rat frontal cortex. Neuropsychopharmacolog y 12: 221-228.
25. Ngwenya LB, Peters A, Rosene DL. 2006. Maturational sequence of newly generated neurons in the dentate gyrus of the young adult rhesus monkey. J Comp Neurol 498: 204-216. (Pubitemid 44182461)
26. Nikiforuk A, Popik P. 2011. Long-lasting cognitive deficit induced by stress is alleviated by acute administration of antidepressants. Psychoneuroendocrinology 36: 28-39.
27. Olypher A.V., Klement D, Fenton AA. 2006. Cognitive disorganization in hippocampus: a physiological model of the disorganization in psychosis. J Neurosci 26(1): 158-168. (Pubitemid 43089528)
28. Perera TD, Coplan JD, Lisanby S.H., Lipira CM, Arif M, Carpio C, et al. 2007. Antidepressant-induced neurogenesis in the hippocampus of adult nonhuman primates. J Neurosci 27(18): 4894-4901. (Pubitemid 46699055)
29. Perera TD, Park S, Nemirovskaya Y. 2008. Cognitive role of neurogenesis in depression and antidepressant treatment. Neuroscientist 14(4): 326-338. (Pubitemid 352010067)
30. Perera TD, Dwork AJ, Keegan K.A., Thirumangalakudi L., Lipira CM, Joyce N, et al. 2011a. Necessity of hippocampal neurogenesis for the therapeutic action of antidepressants in adult nonhuman primates. PLoS One 6(4): e17600.
31. Perera TD, Lu D, Thirumangalakudi L., Smith EL, Yaretskiy A, Rosenblum LA, et al. 2011b. Correlations between hippocampal neurogenesis and metabolic indices in adult nonhuman primates. Neural Plast. 2011: 1-6.
32. Roche M, Harkin A, Kelly JP. 2007. Chronic fluoxetine treatment attenuates stressor-induced changes in temperature, heart rate, and neuronal activation in the olfactory bulbectomized rat. Neuropsychopharmacology 32: 1312-1320. (Pubitemid 46788856)
33. Sahay A, Scobie KN, Hill A.S., O'Carroll CM, Kheirbek MA, Burghardt N.S., et al. 2011. Increasing adult hippocampal neurogenesis is sufficient to improve pattern separation. Nature 472: 466-70.
34. Santarelli L, Saxe M, Gross C., Surget A, Battaglia F, Dulawa S., et al. 2003. Requirement of hippocampal neurogenesis for the behavioral effects of antidepressants. Science 301(5634): 805-809. (Pubitemid 36962615)
35. Saxe M, Malleret G, Vronskaya S., Mendez I, Garcia AD, Sofroniew M.V., et al. 2007. Paradoxical influence of hippocampal neurogenesis on working memory. Proc Natl Acad Sci USA 104: 4642-4646. (Pubitemid 47186278)
36. Shors TJ, Miesegaes G, Beylin A., Zhao M, Rydel T, Gould E. 2001. Neurogenesis in the adult is involved in the formation of trace memories. Nature 410(6826): 372-376. (Pubitemid 32246054)
37. Shors TJ, Mathew J, Sisti H.M., Edgecomb C., Beckoff S, Dalla C. 2007. Neurogenesis and helplessness are mediated by controllability in males but not in females. Biol Psychiatry 62(5): 487-495. (Pubitemid 47284029)
38. Snyder JS, Hong NS, McDonald R.J., Wojtowicz JM. 2005. A role for adult neurogenesis in spatial long-term memory. Neuroscience 130(4): 843-852. (Pubitemid 40094618)
39. Tashiro A, Makino H, Gage FH. 2007. Experience-specific functional modification of the dentate gyrus through adult neurogenesis: a critical period during an immature stage. J Neurosci 27(12): 3252-3259. (Pubitemid 46474131)
40. Wang JW, David DJ, Monckton J.E., Battaglia F., Hen R. 2008. Chronic fluoxetine stimulates maturation and synaptic plasticity of adultborn hippocampal granule cells. J Neurosci 28: 1374-1384. (Pubitemid 351231535)
41. Winocur G, Wojtowicz JM, Sekeres M, Snyder J.S., Wang S. 2006. Inhibition of neurogenesis interferes with hippocampus-dependent memory function. Hippocampus 16(3): 296-304.
42. Wiskott L, Rasch MJ, Kempermann G. 2006. A functional hypothesis for adult hippocampal neurogenesis: avoidance of catastrophic interference in the dentate gyrus. Hippocampus 16(3): 329-343.
43. Xu H, Chen Z, He J., Haimanot S, Li X, Dyck L., Li XM. 2006. Synergetic effects of quetiapine and venlafaxine in preventing the chronic restraint stress-induced decrease in cell proliferation and BDNF expression in rat hippocampus. Hippocampus 16(6): 551-559. (Pubitemid 43942103)