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Volumn 134, Issue 3, 2014, Pages 563-574

T cells in the human metastatic melanoma microenvironment express site-specific homing receptors and retention integrins

Author keywords

cancer immunology; chemokine receptor; integrin; metastatic melanoma; tumor microenvironment

Indexed keywords

CHEMOKINE RECEPTOR CCR4; CHEMOKINE RECEPTOR CCR5; CHEMOKINE RECEPTOR CCR9; CHEMOKINE RECEPTOR CXCR3; ENDOTHELIAL LEUKOCYTE ADHESION MOLECULE 1; HOMING RECEPTOR; INTEGRIN; INTEGRIN ALPHA2BETA2; INTEGRIN ALPHA4BETA7; INTEGRIN ALPHAEBETA7; LYMPHOCYTE ANTIGEN; UNCLASSIFIED DRUG; VERY LATE ACTIVATION ANTIGEN 1; VERY LATE ACTIVATION ANTIGEN 2; VERY LATE ACTIVATION ANTIGEN 4;

EID: 84887865311     PISSN: 00207136     EISSN: 10970215     Source Type: Journal    
DOI: 10.1002/ijc.28391     Document Type: Article
Times cited : (38)

References (49)
  • 1
    • 0030052833 scopus 로고    scopus 로고
    • Tumor infiltrating lymphocytes in lymph node melanoma metastases: A histopathologic prognostic indicator and an expression of local immune response
    • Mihm MC, Jr, Clemente CG, Cascinelli N,. Tumor infiltrating lymphocytes in lymph node melanoma metastases: a histopathologic prognostic indicator and an expression of local immune response. Lab Invest 1996; 74: 43-7.
    • (1996) Lab Invest , vol.74 , pp. 43-47
    • Mihm, Jr.M.C.1    Clemente, C.G.2    Cascinelli, N.3
  • 2
    • 73949140415 scopus 로고    scopus 로고
    • Immune profile and mitotic index of metastatic melanoma lesions enhance clinical staging in predicting patient survival
    • Bogunovic D, O'Neill DW, Belitskaya-Levy I, et al. Immune profile and mitotic index of metastatic melanoma lesions enhance clinical staging in predicting patient survival. Proc Natl Acad Sci USA 2009; 106: 20429-34.
    • (2009) Proc Natl Acad Sci USA , vol.106 , pp. 20429-20434
    • Bogunovic, D.1    O'Neill, D.W.2    Belitskaya-Levy, I.3
  • 3
    • 84857746620 scopus 로고    scopus 로고
    • Immunotype and immunohistologic characteristics of tumor-infiltrating immune cells are associated with clinical outcome in metastatic melanoma
    • Erdag G, Schaefer JT, Smolkin ME, et al. Immunotype and immunohistologic characteristics of tumor-infiltrating immune cells are associated with clinical outcome in metastatic melanoma. Cancer Res 2012; 72: 1070-80.
    • (2012) Cancer Res , vol.72 , pp. 1070-1080
    • Erdag, G.1    Schaefer, J.T.2    Smolkin, M.E.3
  • 4
    • 66749147292 scopus 로고    scopus 로고
    • Integrin function in T-Cell homing to lymphoid and nonlymphoid sites: Getting there and staying there
    • DeNucci CC, Mitchell JS, Shimizu Y,. Integrin function in T-Cell homing to lymphoid and nonlymphoid sites: getting there and staying there. Crit Rev Immunol 2009; 29: 87-109.
    • (2009) Crit Rev Immunol , vol.29 , pp. 87-109
    • Denucci, C.C.1    Mitchell, J.S.2    Shimizu, Y.3
  • 5
    • 80054771138 scopus 로고    scopus 로고
    • Overview of integrin signaling in the immune system
    • Kinashi T,. Overview of integrin signaling in the immune system. Meth Mol Biol 2012; 757: 261-78.
    • (2012) Meth Mol Biol , vol.757 , pp. 261-278
    • Kinashi, T.1
  • 6
    • 34447314985 scopus 로고    scopus 로고
    • Integrin modulation and signaling in leukocyte adhesion and migration
    • Rose DM, Alon R, Ginsberg MH,. Integrin modulation and signaling in leukocyte adhesion and migration. Immunol Rev 2007; 218: 126-34.
    • (2007) Immunol Rev , vol.218 , pp. 126-134
    • Rose, D.M.1    Alon, R.2    Ginsberg, M.H.3
  • 7
    • 33846504106 scopus 로고    scopus 로고
    • Dendritic cell immunization route determines integrin expression and lymphoid and nonlymphoid tissue distribution of CD8 T cells
    • Sheasley-O'Neill SL, Brinkman CC, Ferguson AR, et al. Dendritic cell immunization route determines integrin expression and lymphoid and nonlymphoid tissue distribution of CD8 T cells. J Immunol 2007; 178: 1512-22.
    • (2007) J Immunol , vol.178 , pp. 1512-1522
    • Sheasley-O'Neill, S.L.1    Brinkman, C.C.2    Ferguson, A.R.3
  • 8
    • 77952777105 scopus 로고    scopus 로고
    • CD8 T cells activated in distinct lymphoid organs differentially express adhesion proteins and coexpress multiple chemokine receptors
    • Ferguson AR, Engelhard VH,. CD8 T cells activated in distinct lymphoid organs differentially express adhesion proteins and coexpress multiple chemokine receptors. J Immunol 2010; 184: 4079-86.
    • (2010) J Immunol , vol.184 , pp. 4079-4086
    • Ferguson, A.R.1    Engelhard, V.H.2
  • 9
    • 66149156276 scopus 로고    scopus 로고
    • Chemokine expression in melanoma metastases associated with CD8+ T-cell recruitment
    • Harlin H, Meng Y, Peterson AC, et al. Chemokine expression in melanoma metastases associated with CD8+ T-cell recruitment. Cancer Res 2009; 69: 3077-85.
    • (2009) Cancer Res , vol.69 , pp. 3077-3085
    • Harlin, H.1    Meng, Y.2    Peterson, A.C.3
  • 10
    • 34447132205 scopus 로고    scopus 로고
    • Preferential expression of very late antigen-4 on type 1 CTL cells plays a critical role in trafficking into central nervous system tumors
    • Sasaki K, Zhu X, Vasquez C, et al. Preferential expression of very late antigen-4 on type 1 CTL cells plays a critical role in trafficking into central nervous system tumors. Cancer Res 2007; 67: 6451-8.
    • (2007) Cancer Res , vol.67 , pp. 6451-6458
    • Sasaki, K.1    Zhu, X.2    Vasquez, C.3
  • 11
    • 84868488012 scopus 로고    scopus 로고
    • Tissue-specific homing of immune cells in malignant skin tumors
    • Jokai H, Marschalko M, Csomor J, et al. Tissue-specific homing of immune cells in malignant skin tumors. Pathol Oncol Res 2012; 18: 749-59.
    • (2012) Pathol Oncol Res , vol.18 , pp. 749-759
    • Jokai, H.1    Marschalko, M.2    Csomor, J.3
  • 12
    • 77956527209 scopus 로고    scopus 로고
    • Dynamic changes in cellular infiltrates with repeated cutaneous vaccination: A histologic and immunophenotypic analysis
    • Schaefer JT, Patterson JW, Deacon DH, et al. Dynamic changes in cellular infiltrates with repeated cutaneous vaccination: a histologic and immunophenotypic analysis. J Transl Med 2010; 8: 79-91.
    • (2010) J Transl Med , vol.8 , pp. 79-91
    • Schaefer, J.T.1    Patterson, J.W.2    Deacon, D.H.3
  • 13
    • 2142730100 scopus 로고    scopus 로고
    • Central memory and effector memory T cell subsets: Function, generation, and maintenance
    • Sallusto F, Geginat J, Lanzavecchia A,. Central memory and effector memory T cell subsets: function, generation, and maintenance. Annu Rev Immunol 2004; 22: 745-63.
    • (2004) Annu Rev Immunol , vol.22 , pp. 745-763
    • Sallusto, F.1    Geginat, J.2    Lanzavecchia, A.3
  • 14
    • 0021185599 scopus 로고
    • Lymphocyte activation antigens. I. A monoclonal antibody, anti-Act I, defines a new late lymphocyte activation antigen
    • Lazarovits AI, Moscicki RA, Kurnick JT, et al. Lymphocyte activation antigens. I. A monoclonal antibody, anti-Act I, defines a new late lymphocyte activation antigen. J Immunol 1984; 133: 1857-62.
    • (1984) J Immunol , vol.133 , pp. 1857-1862
    • Lazarovits, A.I.1    Moscicki, R.A.2    Kurnick, J.T.3
  • 15
    • 33749319703 scopus 로고    scopus 로고
    • Type, density, and location of immune cells within human colorectal tumors predict clinical outcome
    • Galon J, Costes A, Sanchez-Cabo F, et al. Type, density, and location of immune cells within human colorectal tumors predict clinical outcome. Science 2006; 313: 1960-4.
    • (2006) Science , vol.313 , pp. 1960-1964
    • Galon, J.1    Costes, A.2    Sanchez-Cabo, F.3
  • 16
    • 77958012775 scopus 로고    scopus 로고
    • Gene signature in melanoma associated with clinical activity: A potential clue to unlock cancer immunotherapy
    • Gajewski TF, Louahed J, Brichard VG,. Gene signature in melanoma associated with clinical activity: a potential clue to unlock cancer immunotherapy. Cancer J 2010; 16: 399-403.
    • (2010) Cancer J , vol.16 , pp. 399-403
    • Gajewski, T.F.1    Louahed, J.2    Brichard, V.G.3
  • 17
    • 77954801902 scopus 로고    scopus 로고
    • Immune signatures predict prognosis in localized cancer
    • Hsu DS, Kim MK, Balakumaran BS, et al. Immune signatures predict prognosis in localized cancer. Cancer Invest 2010; 28: 765-73.
    • (2010) Cancer Invest , vol.28 , pp. 765-773
    • Hsu, D.S.1    Kim, M.K.2    Balakumaran, B.S.3
  • 18
    • 82555205468 scopus 로고    scopus 로고
    • Molecular insights on the peripheral and intratumoral effects of systemic high-dose rIL-2 (aldesleukin) administration for the treatment of metastatic melanoma
    • Weiss GR, Grosh WW, Chianese-Bullock KA, et al. Molecular insights on the peripheral and intratumoral effects of systemic high-dose rIL-2 (aldesleukin) administration for the treatment of metastatic melanoma. Clin Cancer Res 2011; 17: 7440-50.
    • (2011) Clin Cancer Res , vol.17 , pp. 7440-7450
    • Weiss, G.R.1    Grosh, W.W.2    Chianese-Bullock, K.A.3
  • 19
    • 77949780426 scopus 로고    scopus 로고
    • Biomolecular network reconstruction identifies T-cell homing factors associated with survival in colorectal cancer
    • Mlecnik B, Tosolini M, Charoentong P, et al. Biomolecular network reconstruction identifies T-cell homing factors associated with survival in colorectal cancer. Gastroenterology 2010; 138: 1429-40.
    • (2010) Gastroenterology , vol.138 , pp. 1429-1440
    • Mlecnik, B.1    Tosolini, M.2    Charoentong, P.3
  • 20
    • 68049143325 scopus 로고    scopus 로고
    • Intratumoral induction of CD103 triggers tumor-specific CTL function and CCR5-dependent T-cell retention
    • Franciszkiewicz K, Le Floc'h A, Jalil A, et al. Intratumoral induction of CD103 triggers tumor-specific CTL function and CCR5-dependent T-cell retention. Cancer Res 2009; 69: 6249-55.
    • (2009) Cancer Res , vol.69 , pp. 6249-6255
    • Franciszkiewicz, K.1    Le Floc'H, A.2    Jalil, A.3
  • 21
    • 50049106591 scopus 로고    scopus 로고
    • Environmental cues, dendritic cells and the programming of tissue-selective lymphocyte trafficking
    • Sigmundsdottir H, Butcher EC,. Environmental cues, dendritic cells and the programming of tissue-selective lymphocyte trafficking. Nat Immunol 2008; 9: 981-7.
    • (2008) Nat Immunol , vol.9 , pp. 981-987
    • Sigmundsdottir, H.1    Butcher, E.C.2
  • 22
    • 34249105628 scopus 로고    scopus 로고
    • T-cell distribution and adhesion receptor expression in metastatic melanoma
    • Weishaupt C, Munoz KN, Buzney E, et al. T-cell distribution and adhesion receptor expression in metastatic melanoma. Clin Cancer Res 2007; 13: 2549-56.
    • (2007) Clin Cancer Res , vol.13 , pp. 2549-2556
    • Weishaupt, C.1    Munoz, K.N.2    Buzney, E.3
  • 23
    • 53349153303 scopus 로고    scopus 로고
    • Human squamous cell carcinomas evade the immune response by down-regulation of vascular E-selectin and recruitment of regulatory T cells
    • Clark RA, Huang SJ, Murphy GF, et al. Human squamous cell carcinomas evade the immune response by down-regulation of vascular E-selectin and recruitment of regulatory T cells. J Exp Med 2008; 205: 2221-34.
    • (2008) J Exp Med , vol.205 , pp. 2221-2234
    • Clark, R.A.1    Huang, S.J.2    Murphy, G.F.3
  • 24
    • 0028924988 scopus 로고
    • Endothelial vascular cell adhesion molecule 1 expression is suppressed by melanoma and carcinoma
    • Piali L, Fichtel A, Terpe HJ, et al. Endothelial vascular cell adhesion molecule 1 expression is suppressed by melanoma and carcinoma. J Exp Med 1995; 181: 811-6.
    • (1995) J Exp Med , vol.181 , pp. 811-816
    • Piali, L.1    Fichtel, A.2    Terpe, H.J.3
  • 25
    • 0035892915 scopus 로고    scopus 로고
    • CXCR3 internalization following T cell-endothelial cell contact: Preferential role of IFN-inducible T cell alpha chemoattractant (CXCL11)
    • Sauty A, Colvin RA, Wagner L, et al. CXCR3 internalization following T cell-endothelial cell contact: preferential role of IFN-inducible T cell alpha chemoattractant (CXCL11). J Immunol 2001; 167: 7084-93.
    • (2001) J Immunol , vol.167 , pp. 7084-7093
    • Sauty, A.1    Colvin, R.A.2    Wagner, L.3
  • 26
    • 45549098590 scopus 로고    scopus 로고
    • The chemokine receptor CXCR3 is degraded following internalization and is replenished at the cell surface by de novo synthesis of receptor
    • Meiser A, Mueller A, Wise EL, et al. The chemokine receptor CXCR3 is degraded following internalization and is replenished at the cell surface by de novo synthesis of receptor. J Immunol 2008; 180: 6713-24.
    • (2008) J Immunol , vol.180 , pp. 6713-6724
    • Meiser, A.1    Mueller, A.2    Wise, E.L.3
  • 27
    • 77950370339 scopus 로고    scopus 로고
    • Phase II trial of imiquimod and HPV therapeutic vaccination in patients with vulval intraepithelial neoplasia
    • Daayana S, Elkord E, Winters U, et al. Phase II trial of imiquimod and HPV therapeutic vaccination in patients with vulval intraepithelial neoplasia. Br J Cancer 2010; 102: 1129-36.
    • (2010) Br J Cancer , vol.102 , pp. 1129-1136
    • Daayana, S.1    Elkord, E.2    Winters, U.3
  • 28
    • 75649110039 scopus 로고    scopus 로고
    • Molecular pathways mediating differential responses to lipopolysaccharide between human and baboon arterial endothelial cells
    • Shi Q, Cox LA, Glenn J, et al. Molecular pathways mediating differential responses to lipopolysaccharide between human and baboon arterial endothelial cells. Clin Exp Pharmacol P 2010; 37: 178-84.
    • (2010) Clin Exp Pharmacol P , vol.37 , pp. 178-184
    • Shi, Q.1    Cox, L.A.2    Glenn, J.3
  • 29
    • 33845497259 scopus 로고    scopus 로고
    • Interferon-beta and adhesion molecules (E-selectin and s-intracellular adhesion motecule-1) are detected in sera from patients with retinal vasculitis and are induced in retinal vascular endothelial cells by Toll-like receptor 3 signalling
    • Lee MT, Hooper LC, Kump L, et al. Interferon-beta and adhesion molecules (E-selectin and s-intracellular adhesion motecule-1) are detected in sera from patients with retinal vasculitis and are induced in retinal vascular endothelial cells by Toll-like receptor 3 signalling. Clin Exp Immunol 2007; 147: 71-80.
    • (2007) Clin Exp Immunol , vol.147 , pp. 71-80
    • Lee, M.T.1    Hooper, L.C.2    Kump, L.3
  • 30
    • 78149280468 scopus 로고    scopus 로고
    • Interferons induce CXCR3-cognate chemokine production by human metastatic melanoma
    • Dengel LT, Norrod AG, Gregory BL, et al. Interferons induce CXCR3-cognate chemokine production by human metastatic melanoma. J Immunother 2010; 33: 965-74.
    • (2010) J Immunother , vol.33 , pp. 965-974
    • Dengel, L.T.1    Norrod, A.G.2    Gregory, B.L.3
  • 31
    • 79959712939 scopus 로고    scopus 로고
    • CD103 is a hallmark of tumor-infiltrating regulatory T cells
    • Anz D, Mueller W, Golic M, et al. CD103 is a hallmark of tumor-infiltrating regulatory T cells. Int J Cancer 2011; 129: 2417-26.
    • (2011) Int J Cancer , vol.129 , pp. 2417-2426
    • Anz, D.1    Mueller, W.2    Golic, M.3
  • 32
    • 0031572578 scopus 로고    scopus 로고
    • The epithelial cell-specific integrin, CD103 (alpha e integrin), defines a novel subset of alloreactive CD8+ CTL
    • Hadley GA, Bartlett ST, Via CS, et al. The epithelial cell-specific integrin, CD103 (alpha E integrin), defines a novel subset of alloreactive CD8+ CTL. J Immunol 1997; 159: 3748-56.
    • (1997) J Immunol , vol.159 , pp. 3748-3756
    • Hadley, G.A.1    Bartlett, S.T.2    Via, C.S.3
  • 33
    • 80052555420 scopus 로고    scopus 로고
    • Different patterns of peripheral migration by memory CD4+ and CD8+ T cells
    • Gebhardt T, Whitney PG, Zaid A, et al. Different patterns of peripheral migration by memory CD4+ and CD8+ T cells. Nature 2011; 477: 216-9.
    • (2011) Nature , vol.477 , pp. 216-219
    • Gebhardt, T.1    Whitney, P.G.2    Zaid, A.3
  • 34
    • 77951648712 scopus 로고    scopus 로고
    • Identification of a unique population of tissue-memory CD4+ T cells in the airways after influenza infection that is dependent on the integrin VLA-1
    • Chapman TJ, Topham DJ,. Identification of a unique population of tissue-memory CD4+ T cells in the airways after influenza infection that is dependent on the integrin VLA-1. J Immunol 2010; 184: 3841-9.
    • (2010) J Immunol , vol.184 , pp. 3841-3849
    • Chapman, T.J.1    Topham, D.J.2
  • 35
    • 35748943821 scopus 로고    scopus 로고
    • The effect of blockade of tumor necrosis factor alpha on VLA-1+ T-cells in rheumatoid arthritis patients
    • Ben-Horin S, Goldstein I, Koltakov A, et al. The effect of blockade of tumor necrosis factor alpha on VLA-1+ T-cells in rheumatoid arthritis patients. J Clin Immunol 2007; 27: 580-8.
    • (2007) J Clin Immunol , vol.27 , pp. 580-588
    • Ben-Horin, S.1    Goldstein, I.2    Koltakov, A.3
  • 36
    • 34447124969 scopus 로고    scopus 로고
    • Alpha1beta1 integrin is crucial for accumulation of epidermal T cells and the development of psoriasis
    • Conrad C, Boyman O, Tonel G, et al. Alpha1beta1 integrin is crucial for accumulation of epidermal T cells and the development of psoriasis. Nat Med 2007; 13: 836-42.
    • (2007) Nat Med , vol.13 , pp. 836-842
    • Conrad, C.1    Boyman, O.2    Tonel, G.3
  • 37
    • 33847220404 scopus 로고    scopus 로고
    • Modulation of experimental autoimmune encephalomyelitis by VLA-2 blockade
    • Tsunoda I, Terry EJ, Marble BJ, et al. Modulation of experimental autoimmune encephalomyelitis by VLA-2 blockade. Brain Pathol 2007; 17: 45-55.
    • (2007) Brain Pathol , vol.17 , pp. 45-55
    • Tsunoda, I.1    Terry, E.J.2    Marble, B.J.3
  • 38
    • 0036109159 scopus 로고    scopus 로고
    • Memory CD8+ T cells vary in differentiation phenotype in different persistent virus infections
    • Appay V, Dunbar PR, Callan M, et al. Memory CD8+ T cells vary in differentiation phenotype in different persistent virus infections. Nat Med 2002; 8: 379-85.
    • (2002) Nat Med , vol.8 , pp. 379-385
    • Appay, V.1    Dunbar, P.R.2    Callan, M.3
  • 39
    • 33748967590 scopus 로고    scopus 로고
    • Ex-vivo analysis of CD8+ T cells infiltrating colorectal tumors identifies a major effector-memory subset with low perforin content
    • Ye SW, Wang Y, Valmori D, et al. Ex-vivo analysis of CD8+ T cells infiltrating colorectal tumors identifies a major effector-memory subset with low perforin content. J Clin Immunol 2006; 26: 447-56.
    • (2006) J Clin Immunol , vol.26 , pp. 447-456
    • Ye, S.W.1    Wang, Y.2    Valmori, D.3
  • 40
    • 78049500522 scopus 로고    scopus 로고
    • Recruitment of CCR6-Expressing Th17 Cells by CCL 20 Secreted from IL-1 beta-, TNF-alpha-, and IL-17A-Stimulated Endometriotic Stromal Cells
    • Hirata T, Osuga Y, Takamura M, et al. Recruitment of CCR6-Expressing Th17 Cells by CCL 20 Secreted from IL-1 beta-, TNF-alpha-, and IL-17A-Stimulated Endometriotic Stromal Cells. Endocrinology 2010; 151: 5468-76.
    • (2010) Endocrinology , vol.151 , pp. 5468-5476
    • Hirata, T.1    Osuga, Y.2    Takamura, M.3
  • 41
    • 33750530395 scopus 로고    scopus 로고
    • CCR5-dependent homing of naturally occurring CD4(+) regulatory T cells to sites of Leishmania major infection favors pathogen persistence
    • Yurchenko E, Tritt M, Hay V, et al. CCR5-dependent homing of naturally occurring CD4(+) regulatory T cells to sites of Leishmania major infection favors pathogen persistence. J Exp Med 2006; 203: 2451-60.
    • (2006) J Exp Med , vol.203 , pp. 2451-2460
    • Yurchenko, E.1    Tritt, M.2    Hay, V.3
  • 42
    • 84856733781 scopus 로고    scopus 로고
    • Extended co-expression of inhibitory receptors by human CD8 T-cells depending on differentiation, antigen-specificity and anatomical localization
    • Baitsch L, Legat A, Barba L, et al. Extended co-expression of inhibitory receptors by human CD8 T-cells depending on differentiation, antigen-specificity and anatomical localization. PLoS One 2012; 7: e30852.
    • (2012) PLoS One , vol.7
    • Baitsch, L.1    Legat, A.2    Barba, L.3
  • 43
    • 84863393290 scopus 로고    scopus 로고
    • CD8(+) T cells specific for tumor antigens can be rendered dysfunctional by the tumor microenvironment through upregulation of the inhibitory receptors BTLA and PD-1
    • Fourcade J, Sun Z, Pagliano O, et al. CD8(+) T cells specific for tumor antigens can be rendered dysfunctional by the tumor microenvironment through upregulation of the inhibitory receptors BTLA and PD-1. Cancer Res 2012; 72: 887-96.
    • (2012) Cancer Res , vol.72 , pp. 887-896
    • Fourcade, J.1    Sun, Z.2    Pagliano, O.3
  • 44
    • 66949111877 scopus 로고    scopus 로고
    • PD-1 is a regulator of NY-ESO-1-specific CD8+ T cell expansion in melanoma patients
    • Fourcade J, Kudela P, Sun Z, et al. PD-1 is a regulator of NY-ESO-1-specific CD8+ T cell expansion in melanoma patients. J Immunol 2009; 182: 5240-9.
    • (2009) J Immunol , vol.182 , pp. 5240-5249
    • Fourcade, J.1    Kudela, P.2    Sun, Z.3
  • 45
    • 66949111877 scopus 로고    scopus 로고
    • PD-1 Is a Regulator of NY-ESO-1-Specific CD8(+) T Cell Expansion in Melanoma Patients
    • Fourcade J, Kudela P, Sun ZJ, et al. PD-1 Is a Regulator of NY-ESO-1-Specific CD8(+) T Cell Expansion in Melanoma Patients. J Immunol 2009; 182: 5240-9.
    • (2009) J Immunol , vol.182 , pp. 5240-5249
    • Fourcade, J.1    Kudela, P.2    Sun, Z.J.3
  • 46
    • 77954373338 scopus 로고    scopus 로고
    • Selective BRAFV600E inhibition enhances T-cell recognition of melanoma without affecting lymphocyte function
    • Boni A, Cogdill AP, Dang P, et al. Selective BRAFV600E inhibition enhances T-cell recognition of melanoma without affecting lymphocyte function. Cancer Res 2010; 70: 5213-9.
    • (2010) Cancer Res , vol.70 , pp. 5213-5219
    • Boni, A.1    Cogdill, A.P.2    Dang, P.3
  • 47
    • 84863393623 scopus 로고    scopus 로고
    • Selective BRAF inhibitors induce marked T-cell infiltration into human metastatic melanoma
    • Wilmott JS, Long GV, Howle JR, et al. Selective BRAF inhibitors induce marked T-cell infiltration into human metastatic melanoma. Clin Cancer Res 2012; 18: 1386-94.
    • (2012) Clin Cancer Res , vol.18 , pp. 1386-1394
    • Wilmott, J.S.1    Long, G.V.2    Howle, J.R.3
  • 48
    • 58949102534 scopus 로고    scopus 로고
    • Intratumoral immune cell infiltrates, FoxP3, and indoleamine 2,3-dioxygenase in patients with melanoma undergoing CTLA4 blockade
    • Ribas A, Comin-Anduix B, Economou JS, et al. Intratumoral immune cell infiltrates, FoxP3, and indoleamine 2,3-dioxygenase in patients with melanoma undergoing CTLA4 blockade. Clin Cancer Res 2009; 15: 390-9.
    • (2009) Clin Cancer Res , vol.15 , pp. 390-399
    • Ribas, A.1    Comin-Anduix, B.2    Economou, J.S.3
  • 49
    • 84867544962 scopus 로고    scopus 로고
    • PD-1 blockade enhances T-cell migration to tumors by elevating IFN-gamma inducible chemokines
    • Peng W, Liu C, Xu C, et al. PD-1 blockade enhances T-cell migration to tumors by elevating IFN-gamma inducible chemokines. Cancer Res 2012; 72: 5209-18.
    • (2012) Cancer Res , vol.72 , pp. 5209-5218
    • Peng, W.1    Liu, C.2    Xu, C.3


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