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Volumn 35, Issue 6, 2013, Pages 649-652

Potential for novel MUC1 glycopeptide-specific antibody in passive cancer immunotherapy

Author keywords

ADCC; Antibody; Immunotherapy; MUC1; NK cell

Indexed keywords

ALPHA INTERFERON; EPITOPE; GLYCOPEPTIDE; INTERLEUKIN 2; MONOCLONAL ANTIBODY; MONOCLONAL ANTIBODY 5E5; MUCIN 1; PANKOMAB; UNCLASSIFIED DRUG;

EID: 84887864047     PISSN: 08923973     EISSN: 15322513     Source Type: Journal    
DOI: 10.3109/08923973.2013.837060     Document Type: Review
Times cited : (9)

References (57)
  • 1
    • 70450247207 scopus 로고    scopus 로고
    • Mucins in cancer: Function, prognosis and therapy
    • Kufe DW. Mucins in cancer: function, prognosis and therapy. Nat Rev Cancer 2009;9:874-885.
    • (2009) Nat Rev Cancer , vol.9 , pp. 874-885
    • Kufe, D.W.1
  • 3
    • 40749160803 scopus 로고    scopus 로고
    • Mucin-type O-glycosylation and its potential use in drug and vaccine development
    • DOI 10.1016/j.bbagen.2007.09.010, PII S0304416507002164
    • Tarp MA, Clausen H. Mucin-type O-glycosylation and its potential use in drug and vaccine development. Biochim Biophys Acta 2008; 1780:546-563. (Pubitemid 351381249)
    • (2008) Biochimica et Biophysica Acta - General Subjects , vol.1780 , Issue.3 , pp. 546-563
    • Tarp, M.A.1    Clausen, H.2
  • 4
    • 0347123435 scopus 로고    scopus 로고
    • Mucins in cancer: Protection and control of the cell surface
    • Hollingsworth MA, Swanson BJ. Mucins in cancer: protection and control of the cell surface. Nat Rev Cancer 2004;4:45-60. (Pubitemid 38082153)
    • (2004) Nature Reviews Cancer , vol.4 , Issue.1 , pp. 45-60
    • Hollingsworth, M.A.1    Swanson, B.J.2
  • 5
    • 0035077832 scopus 로고    scopus 로고
    • O-glycosylation of the mucin type
    • Hanisch FG. O-glycosylation of the mucin type. Biol Chem 2001; 382:143-149.
    • (2001) Biol Chem , vol.382 , pp. 143-149
    • Hanisch, F.G.1
  • 7
    • 77953161781 scopus 로고    scopus 로고
    • Regulation of O-glycosylation through Golgi-to-ER relocation of initiation enzymes
    • Gill DJ, Chia J, Senewiratne J, Bard F. Regulation of O-glycosylation through Golgi-to-ER relocation of initiation enzymes. J Cell Biol 2010;189:843-858.
    • (2010) J Cell Biol , vol.189 , pp. 843-858
    • Gill, D.J.1    Chia, J.2    Senewiratne, J.3    Bard, F.4
  • 9
    • 34247474805 scopus 로고    scopus 로고
    • Decreased intraperitoneal disease recurrence in epithelial ovarian cancer patients receiving intraperitoneal consolidation treatment with yttrium-90-labeled murine HMFG1 without improvement in overall survival
    • DOI 10.1002/ijc.22663
    • Oei AL, Verheijen RH, Seiden MV, et al. Decreased intraperitoneal disease recurrence in epithelial ovarian cancer patients receiving intraperitoneal consolidation treatment with yttrium-90-labeled murine HMFG1 without improvement in overall survival. Int J Cancer 2007;120:2710-2714. (Pubitemid 46651295)
    • (2007) International Journal of Cancer , vol.120 , Issue.12 , pp. 2710-2714
    • Oei, A.L.1    Verheijen, R.H.2    Seiden, M.V.3    Benigno, B.B.4    Lopes, A.5    Soper, J.T.6    Epenetos, A.A.7    Massuger, L.F.8
  • 10
    • 51949104317 scopus 로고    scopus 로고
    • Induction of IgG antibodies to MUC1 and survival in patients with epithelial ovarian cancer
    • Oei AL, Moreno M, Verheijen RH, et al. Induction of IgG antibodies to MUC1 and survival in patients with epithelial ovarian cancer. Int J Cancer 2008;123:1848-1853.
    • (2008) Int J Cancer , vol.123 , pp. 1848-1853
    • Oei, A.L.1    Moreno, M.2    Verheijen, R.H.3
  • 11
    • 57349181743 scopus 로고    scopus 로고
    • Effect of the antibody immunotherapy by the anti-MUC1 monoclonal antibody to the oral squamous cell carcinoma in vitro
    • Shimizu M, Imai M. Effect of the antibody immunotherapy by the anti-MUC1 monoclonal antibody to the oral squamous cell carcinoma in vitro. Biol Pharm Bull 2008;31:2288-2293.
    • (2008) Biol Pharm Bull , vol.31 , pp. 2288-2293
    • Shimizu, M.1    Imai, M.2
  • 12
    • 80455144484 scopus 로고    scopus 로고
    • Randomized phase II trial of letrozole plus anti-MUC1 antibody AS1402 in hormone receptor-positive locally advanced or metastatic breast cancer
    • Ibrahim NK, Yariz KO, Bondarenko I, et al. Randomized phase II trial of letrozole plus anti-MUC1 antibody AS1402 in hormone receptor-positive locally advanced or metastatic breast cancer. Clin Cancer Res 2011;17:6822-6830.
    • (2011) Clin Cancer Res , vol.17 , pp. 6822-6830
    • Ibrahim, N.K.1    Yariz, K.O.2    Bondarenko, I.3
  • 13
    • 77449106552 scopus 로고    scopus 로고
    • Phase i dose escalation pharmacokinetic assessment of intravenous humanized anti-MUC1 antibody AS1402 in patients with advanced breast cancer
    • 1-8
    • Pegram MD, Borges VF, Ibrahim N, et al. Phase I dose escalation pharmacokinetic assessment of intravenous humanized anti-MUC1 antibody AS1402 in patients with advanced breast cancer. Breast Cancer Res 2009;11:R73 (1-8).
    • (2009) Breast Cancer Res , vol.11
    • Pegram, M.D.1    Borges, V.F.2    Ibrahim, N.3
  • 15
    • 0034947607 scopus 로고    scopus 로고
    • Induction of CA125-specific B and T cell responses in patients injected with MAb-B43.13 - Evidence for antibody-mediated antigen-processing and presentation of CA125 in vivo
    • Noujaim AA, Schultes BC, Baum RP, Madiyalakan R. Induction of CA125-specific B and T cell responses in patients injected with MAb-B43.13 - evidence for antibody-mediated antigen-processing and presentation of CA125 in vivo. Cancer Biother Radiopharm 2001;16:187-203. (Pubitemid 32641217)
    • (2001) Cancer Biotherapy and Radiopharmaceuticals , vol.16 , Issue.3 , pp. 187-203
    • Noujaim, A.A.1    Schultes, B.C.2    Baum, R.P.3    Madiyalakan, R.4
  • 17
    • 80052573203 scopus 로고    scopus 로고
    • Anti-MUC1 monoclonal antibody (C595) and docetaxel markedly reduce tumor burden and ascites, and prolong survival in an in vivo ovarian cancer model
    • Wang L, Chen H, Pourgholami MH, et al. Anti-MUC1 monoclonal antibody (C595) and docetaxel markedly reduce tumor burden and ascites, and prolong survival in an in vivo ovarian cancer model. PLoS One 2011;6:e24405.
    • (2011) PLoS One , vol.6
    • Wang, L.1    Chen, H.2    Pourgholami, M.H.3
  • 18
    • 78649632254 scopus 로고    scopus 로고
    • Monoclonal antibody targeting MUC1 and increasing sensitivity to docetaxel as a novel strategy in treating human epithelial ovarian cancer
    • Wang L, Chen H, Liu F, et al. Monoclonal antibody targeting MUC1 and increasing sensitivity to docetaxel as a novel strategy in treating human epithelial ovarian cancer. Cancer Lett 2011;300: 122-133.
    • (2011) Cancer Lett , vol.300 , pp. 122-133
    • Wang, L.1    Chen, H.2    Liu, F.3
  • 20
    • 33645013588 scopus 로고    scopus 로고
    • Cytotoxicity of PAI2, C595 and Herceptin vectors labeled with the alpha-emitting radioisotope Bismuth-213 for ovarian cancer cell monolayers and clusters
    • Song YJ, Qu CF, Rizvi SM, et al. Cytotoxicity of PAI2, C595 and Herceptin vectors labeled with the alpha-emitting radioisotope Bismuth-213 for ovarian cancer cell monolayers and clusters. Cancer Lett 2006;234:176-183.
    • (2006) Cancer Lett , vol.234 , pp. 176-183
    • Song, Y.J.1    Qu, C.F.2    Rizvi, S.M.3
  • 22
    • 3142670929 scopus 로고    scopus 로고
    • CA125- and tumor-specific T-cell responses correlate with prolonged survival in oregovomab-treated recurrent ovarian cancer patients
    • DOI 10.1016/j.ygyno.2004.04.024, PII S0090825804002781
    • Gordon AN, Schultes BC, Gallion H, et al. CA125-and tumorspecific T-cell responses correlate with prolonged survival in oregovomab-treated recurrent ovarian cancer patients. Gynecol Oncol 2004;94:340-351. (Pubitemid 39024536)
    • (2004) Gynecologic Oncology , vol.94 , Issue.2 , pp. 340-351
    • Gordon, A.N.1    Schultes, B.C.2    Gallion, H.3    Edwards, R.4    Whiteside, T.L.5    Cermak, J.M.6    Nicodemus, C.F.7
  • 23
    • 65549085361 scopus 로고    scopus 로고
    • The Immune adjuvant properties of front-line carboplatin-paclitaxel: A randomized phase 2 study of alternative schedules of intravenous oregovomab chemoimmunotherapy in advanced ovarian cancer
    • Braly P, Nicodemus CF, Chu C, et al. The Immune adjuvant properties of front-line carboplatin-paclitaxel: A randomized phase 2 study of alternative schedules of intravenous oregovomab chemoimmunotherapy in advanced ovarian cancer. J Immunother 2009;32:54-65.
    • (2009) J Immunother , vol.32 , pp. 54-65
    • Braly, P.1    Nicodemus, C.F.2    Chu, C.3
  • 26
    • 34648820280 scopus 로고    scopus 로고
    • High level of MUC1 in serum of ovarian and breast cancer patients inhibits huHMFG-1 dependent cell-mediated cytotoxicity (ADCC)
    • DOI 10.1016/j.canlet.2007.06.016, PII S0304383507002935
    • Moreno M, Bontkes HJ, Scheper RJ, et al. High level of MUC1 in serum of ovarian and breast cancer patients inhibits huHMFG-1 dependent cell-mediated cytotoxicity (ADCC). Cancer Lett 2007; 257:47-55. (Pubitemid 47464696)
    • (2007) Cancer Letters , vol.257 , Issue.1 , pp. 47-55
    • Moreno, M.1    Bontkes, H.J.2    Scheper, R.J.3    Kenemans, P.4    Verheijen, R.H.M.5    Von Mensdorff-Pouilly, S.6
  • 27
    • 84863570663 scopus 로고    scopus 로고
    • Antibody targeting of cellbound MUC1 SEA domain kills tumor cells
    • Pichinuk E, Benhar I, Jacobi O, et al. Antibody targeting of cellbound MUC1 SEA domain kills tumor cells. Cancer Res 2012;72: 3324-3336.
    • (2012) Cancer Res , vol.72 , pp. 3324-3336
    • Pichinuk, E.1    Benhar, I.2    Jacobi, O.3
  • 28
    • 80051704693 scopus 로고    scopus 로고
    • Preparation and biological evaluation of (177)Lu conjugated PR81 for radioimmunotherapy of breast cancer
    • Salouti M, Babaei MH, Rajabi H, Rasaee M. Preparation and biological evaluation of (177)Lu conjugated PR81 for radioimmunotherapy of breast cancer. Nucl Med Biol 2011;38:849-855.
    • (2011) Nucl Med Biol , vol.38 , pp. 849-855
    • Salouti, M.1    Babaei, M.H.2    Rajabi, H.3    Rasaee, M.4
  • 29
    • 77953691469 scopus 로고    scopus 로고
    • Radioimmunotherapy of MCF7 breast cancer cell line with 131IPR81 monoclonal antibody against MUC1: Comparison of direct and indirect radioiodination methods
    • Mohammadnejad J, Rasaee MJ, Babaei MH, et al. Radioimmunotherapy of MCF7 breast cancer cell line with 131IPR81 monoclonal antibody against MUC1: comparison of direct and indirect radioiodination methods. Hum Antibodies 2010;19:15-25.
    • (2010) Hum Antibodies , vol.19 , pp. 15-25
    • Mohammadnejad, J.1    Rasaee, M.J.2    Babaei, M.H.3
  • 31
    • 84871005809 scopus 로고    scopus 로고
    • Intratumoral delivery of CpG-conjugated anti-MUC1 antibody enhances NK cell anti-tumor activity
    • Schettini J, Kidiyoor A, Besmer DM, et al. Intratumoral delivery of CpG-conjugated anti-MUC1 antibody enhances NK cell anti-tumor activity. Cancer Immunol Immunother 2012;61:2055-2065.
    • (2012) Cancer Immunol Immunother , vol.61 , pp. 2055-2065
    • Schettini, J.1    Kidiyoor, A.2    Besmer, D.M.3
  • 32
    • 34548237408 scopus 로고    scopus 로고
    • Epitope mapping of PR81 anti-MUC1 monoclonal antibody following PEPSCAN and phage display techniques
    • Mohammadi M, Rasaee MJ, Rajabibazl M, et al. Epitope mapping of PR81 anti-MUC1 monoclonal antibody following PEPSCAN and phage display techniques. Hybridoma (Larchmt) 2007;26: 223-230.
    • (2007) Hybridoma (Larchmt) , vol.26 , pp. 223-230
    • Mohammadi, M.1    Rasaee, M.J.2    Rajabibazl, M.3
  • 33
    • 76749087478 scopus 로고    scopus 로고
    • Cancer biomarkers defined by autoantibody signatures to aberrant o-glycopeptide epitopes
    • Wandall HH, Blixt O, Tarp MA, et al. Cancer biomarkers defined by autoantibody signatures to aberrant o-glycopeptide epitopes. Cancer Res 2010;70:1306-1313.
    • (2010) Cancer Res , vol.70 , pp. 1306-1313
    • Wandall, H.H.1    Blixt, O.2    Tarp, M.A.3
  • 34
    • 33644506102 scopus 로고    scopus 로고
    • Multiple hepatic receptors cooperate to eliminate secretory mucins aberrantly entering the bloodstream: Are circulating cancer mucins the ''tip of the iceberg''
    • Wahrenbrock MG, Varki A. Multiple hepatic receptors cooperate to eliminate secretory mucins aberrantly entering the bloodstream: Are circulating cancer mucins the ''tip of the iceberg'' Cancer Res 2006;66:2433-2441.
    • (2006) Cancer Res , vol.66 , pp. 2433-2441
    • Wahrenbrock, M.G.1    Varki, A.2
  • 35
    • 84865740810 scopus 로고    scopus 로고
    • Lectins identify glycan biomarkers on glioblastoma-derived cancer stem cells
    • Tucker-Burden C, Chappa P, Krishnamoorthy M, et al. Lectins identify glycan biomarkers on glioblastoma-derived cancer stem cells. Stem Cells Dev 2012;21:2374-2386.
    • (2012) Stem Cells Dev , vol.21 , pp. 2374-2386
    • Tucker-Burden, C.1    Chappa, P.2    Krishnamoorthy, M.3
  • 36
    • 84878314550 scopus 로고    scopus 로고
    • The use of a novel MUC1 antibody to identify cancer stem cells and circulating MUC1 in mice and patients with pancreatic cancer
    • Curry JM, Thompson KJ, Rao SG, et al. The use of a novel MUC1 antibody to identify cancer stem cells and circulating MUC1 in mice and patients with pancreatic cancer. J Surg Oncol 2013;107:713-722.
    • (2013) J Surg Oncol , vol.107 , pp. 713-722
    • Curry, J.M.1    Thompson, K.J.2    Rao, S.G.3
  • 39
    • 0029145928 scopus 로고
    • Monoclonal antibody BW835 defines a site-specific Thomsen-Friedenreich disaccharide linked to threonine within the VTSA motif of MUC1 tandem repeats
    • Hanisch FG, Stadie T, Bosslet K. Monoclonal antibody BW835 defines a site-specific Thomsen-Friedenreich disaccharide linked to threonine within the VTSA motif of MUC1 tandem repeats. Cancer Res 1995;55:4036-4040.
    • (1995) Cancer Res , vol.55 , pp. 4036-4040
    • Hanisch, F.G.1    Stadie, T.2    Bosslet, K.3
  • 40
    • 84861498499 scopus 로고    scopus 로고
    • Determination of MUC1 in sera of ovarian cancer patients and in sera of patients with benign changes of the ovaries with CA15-3, CA27.29, and PankoMab
    • Jeschke U, Wiest I, Schumacher AL, et al. Determination of MUC1 in sera of ovarian cancer patients and in sera of patients with benign changes of the ovaries with CA15-3, CA27.29, and PankoMab. Anticancer Res 2012;32:2185-2189.
    • (2012) Anticancer Res , vol.32 , pp. 2185-2189
    • Jeschke, U.1    Wiest, I.2    Schumacher, A.L.3
  • 41
    • 77954349368 scopus 로고    scopus 로고
    • Reactivity of a humanized antibody (hPankoMab) towards a tumor-related MUC1 epitope (TA-MUC1) with various human carcinomas
    • Fan XN, Karsten U, Goletz S, Cao Y. Reactivity of a humanized antibody (hPankoMab) towards a tumor-related MUC1 epitope (TA-MUC1) with various human carcinomas. Pathol Res Pract 2010;206:585-589.
    • (2010) Pathol Res Pract , vol.206 , pp. 585-589
    • Fan, X.N.1    Karsten, U.2    Goletz, S.3    Cao, Y.4
  • 42
    • 67549118583 scopus 로고    scopus 로고
    • Evaluation of a novel anti-mucin 1 (MUC1) antibody (PankoMab) as a potential diagnostic tool in human ductal breast cancer; Comparison with two established antibodies
    • Dian D, Janni W, Kuhn C, et al. Evaluation of a novel anti-mucin 1 (MUC1) antibody (PankoMab) as a potential diagnostic tool in human ductal breast cancer; comparison with two established antibodies. Onkologie 2009;32:238-244.
    • (2009) Onkologie , vol.32 , pp. 238-244
    • Dian, D.1    Janni, W.2    Kuhn, C.3
  • 43
    • 79951974583 scopus 로고    scopus 로고
    • Seromic profiling of colorectal cancer patients with novel glycopeptide microarray
    • Pedersen JW, Blixt O, Bennett EP, et al. Seromic profiling of colorectal cancer patients with novel glycopeptide microarray. Int J Cancer 2010;128:1860-1871.
    • (2010) Int J Cancer , vol.128 , pp. 1860-1871
    • Pedersen, J.W.1    Blixt, O.2    Bennett, E.P.3
  • 46
    • 78650450703 scopus 로고    scopus 로고
    • Expression of aberrantly glycosylated Mucin-1 in ovarian cancer
    • Van Elssen CH, Frings PW, Bot FJ, et al. Expression of aberrantly glycosylated Mucin-1 in ovarian cancer. Histopathology 2010;57: 597-606.
    • (2010) Histopathology , vol.57 , pp. 597-606
    • Van Elssen, C.H.1    Frings, P.W.2    Bot, F.J.3
  • 47
    • 84876473766 scopus 로고    scopus 로고
    • Aberrantly glycosylated MUC1 is expressed on the surface of breast cancer cells and a target for antibody-dependent cell-mediated cytotoxicity
    • Lavrsen K, Madsen CB, Rasch MG, et al. Aberrantly glycosylated MUC1 is expressed on the surface of breast cancer cells and a target for antibody-dependent cell-mediated cytotoxicity. Glycoconj J 2012;30:227-236.
    • (2012) Glycoconj J , vol.30 , pp. 227-236
    • Lavrsen, K.1    Madsen, C.B.2    RasMcCabe, C.H.G.3
  • 49
    • 0020084343 scopus 로고
    • Effect of human recombinant interferon on cytotoxic activity of natural killer (NK) cells and monocytes
    • Herberman RB, Ortaldo JR, Mantovani A, et al. Effect of human recombinant interferon on cytotoxic activity of natural killer (NK) cells and monocytes. Cell Immunol 1982;67:160-167. (Pubitemid 12189638)
    • (1982) Cellular Immunology , vol.67 , Issue.1 , pp. 160-167
    • Herberman, R.B.1    Ortaldo, J.R.2    Mantovani, A.3
  • 51
    • 35948961556 scopus 로고    scopus 로고
    • The activation of natural killer cell effector functions by cetuximab-coated, epidermal growth factor receptor - Positive tumor cells is enhanced by cytokines
    • DOI 10.1158/1078-0432.CCR-07-0865
    • Roda JM, Joshi T, Butchar JP, et al. The activation of natural killer cell effector functions by cetuximab-coated, epidermal growth factor receptor positive tumor cells is enhanced by cytokines. Clin Cancer Res 2007;13:6419-6428. (Pubitemid 350075032)
    • (2007) Clinical Cancer Research , vol.13 , Issue.21 , pp. 6419-6428
    • Roda, J.M.1    Joshi, T.2    Butchar, J.P.3    McAlees, J.W.4    Lehman, A.5    Tridandapani, S.6    Carson III, W.E.7
  • 52
    • 33846194189 scopus 로고    scopus 로고
    • MUC1-specific immune therapy generates a strong anti-tumor response in a MUC1-tolerant colon cancer model
    • DOI 10.1016/j.vaccine.2006.11.007, PII S0264410X06012035
    • Mukherjee P, Pathangey LB, Bradley JB, et al. MUC1-specific immune therapy generates a strong anti-tumor response in a MUC1-tolerant colon cancer model. Vaccine 2007;25: 1607-1618. (Pubitemid 46108207)
    • (2007) Vaccine , vol.25 , Issue.9 , pp. 1607-1618
    • Mukherjee, P.1    Pathangey, L.B.2    Bradley, J.B.3    Tinder, T.L.4    Basu, G.D.5    Akporiaye, E.T.6    Gendler, S.J.7
  • 53
    • 51549099068 scopus 로고    scopus 로고
    • MUC1 enhances tumor progression and contributes toward immunosuppression in a mouse model of spontaneous pancreatic adenocarcinoma
    • Tinder TL, Subramani DB, Basu GD, et al. MUC1 enhances tumor progression and contributes toward immunosuppression in a mouse model of spontaneous pancreatic adenocarcinoma. J Immunol 2008;181:3116-3125.
    • (2008) J Immunol , vol.181 , pp. 3116-3125
    • Tinder, T.L.1    Subramani, D.B.2    Basu, G.D.3
  • 54
    • 84873990263 scopus 로고    scopus 로고
    • Targeted imaging of breast tumor progression and therapeutic response in a human uMUC-1 expressing transgenic mouse model
    • Ghosh SK, Uchida M, Yoo B, et al. Targeted imaging of breast tumor progression and therapeutic response in a human uMUC-1 expressing transgenic mouse model. Int J Cancer 2013;132: 1860-1867.
    • (2013) Int J Cancer , vol.132 , pp. 1860-1867
    • Ghosh, S.K.1    Uchida, M.2    Yoo, B.3
  • 55
    • 0141955228 scopus 로고    scopus 로고
    • An anti-MUC1-antibody - Interleukin-2 fusion protein that activates resting NK cells to lysis of MUC1-positive tumour cells
    • DOI 10.1038/sj.bjc.6601267
    • Heuser C, Ganser M, Hombach A, et al. An anti-MUC1-antibody-interleukin-2 fusion protein that activates resting NK cells to lysis of MUC1-positive tumour cells. Br J Cancer 2003; 89:1130-1139. (Pubitemid 37243025)
    • (2003) British Journal of Cancer , vol.89 , Issue.6 , pp. 1130-1139
    • Heuser, C.1    Ganser, M.2    Hombach, A.3    Brand, H.4    Denton, G.5    Hanisch, F.-G.6    Abken, H.7
  • 56
    • 0037306396 scopus 로고    scopus 로고
    • Interferon-gamma upregulates MUC1 expression in haematopoietic and epithelial cancer cell lines, an effect associated with MUC1 mRNA induction
    • DOI 10.1016/S0959-8049(02)00700-1, PII S0959804902007001
    • Reddy PK, Gold DV, Cardillo TM, et al. Interferon-gamma upregulates MUC1 expression in haematopoietic and epithelial cancer cell lines, an effect associated with MUC1 mRNA induction. Eur J Cancer 2003;39:397-404. (Pubitemid 36140059)
    • (2003) European Journal of Cancer , vol.39 , Issue.3 , pp. 397-404
    • Reddy, P.K.1    Gold, D.V.2    Cardillo, T.M.3    Goldenberg, D.M.4    Li, H.5    Burton, J.D.6


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