Effects of gender, ejection fraction and weight on cardiac force development in patients undergoing cardiac surgery - an experimental examination

Journal of Cardiothoracic Surgery

Volumn 8, Issue 1, 2013, Pages

  Bening, Constanze ^a   Weiler, Helge ^a   Vahl, Christian Friedrich ^a  

^a UNIVERSITY MEDICAL CENTER MAINZ   (Germany)

Author keywords

Calcium sensitivity; Force relationship; pCa; Skinned fibers

Indexed keywords

CALCIUM;

ADULT; AGED; AORTA VALVE; ARTICLE; BIOLOGICAL MODEL; BODY WEIGHT; CORONARY ARTERY BYPASS GRAFT; FEMALE; HEART; HEART FUNCTION TEST; HEART STROKE VOLUME; HUMAN; MALE; METABOLISM; MIDDLE AGED; PHYSIOLOGY; SEX DIFFERENCE; VERY ELDERLY;

ADULT; AGED; AGED, 80 AND OVER; AORTIC VALVE; BODY WEIGHT; CALCIUM; CORONARY ARTERY BYPASS; FEMALE; HEART; HEART FUNCTION TESTS; HUMANS; MALE; MIDDLE AGED; MODELS, CARDIOVASCULAR; SEX FACTORS; STROKE VOLUME;

EID: 84887640622     PISSN: None     EISSN: 17498090     Source Type: Journal    
DOI: 10.1186/1749-8090-8-214     Document Type: Article

References (34)

1. Bhupathy P, Haines C, Leinwand LA. Influence of sex hormones and phytoestrogens on heart disease in men and women. Womens Health 2010, 6(1):77-95.
2. Konhilas JP. What we know and do not know about sex and cardiac disease. J Biomed Biotechnol Exp Physiol 2010, 2010:562051. Exp Physiol 2009;94(5): 541-52.
3. Bhatia RS, Tu JV, Lee DS, et al. Outcome of heart failure with preserved ejection fraction in a population-based study. N Eng J 2006, 355(3):260-269.
4. Owan TE, Hodge DO, Herges RM, Jacobsen SJ, Roger VL, Redfield MM. Trends in prevalence and outcome of heart failure with preserved ejection fraction. N Eng J 2006, 355(3):251-259.
5. Hsich P, Piña IL. Heart Failure in women. A need for preospective data. J Am Coll Cardiol 2009, 54(6):491-498. 10.1016/j.jacc.2009.02.066, 19643307.
6. Leblanc N, Chartier D, Gosselin H, Rouleau JL. Age and gender differences in excitation-contraction coupling of the rat ventricle. J Physiol 1998, 511(Pt 2):533-548. 2231134, 9706029.
7. Howlett SE. Age-associated changes in excitation-contraction coupling are more prominent in ventricular myocytes from male rats than in myocytes from female rats. Am J Physiol Heart Circ Physiol 2010, 298(2):H659-H670. 10.1152/ajpheart.00214.2009, 19966062.
8. Look C, Morrano I, Lamounier-Zepter V. Human adipocyte-derived factors directly inhibit cardiac contraction. J Muscle Res Cell Motil 2008, 29:181-184. 10.1007/s10974-009-9172-2, 19247583.
9. Grandy SA, Howeltt SE. Cardiac excitation-contraction coupling is altered in myocytes from aged male mice but not in cells from aged female mice. Am J Physiol Heart Circ Physiol 2006, 291(5):H2362-H2370. 10.1152/ajpheart.00070.2006, 16731653.
10. Gorza L, Vettore S, Tessaro A, Sorrentino V, Vitadello M. Regional and age-related differences in mRNA composition of intracellular Ca(2+)-release channels of rat cardiac myocytes. J Mol Cell Cardiol 1997, 29(3):1023-1026. 10.1006/jmcc.1996.0346, 9152863.
11. Cordeiro JM, Malone JE, Diego JM, Scornik FS, Aistruo GL, Antzelevitch C, Wasserstrom JA. Cellular and subcellular alternans in the canine left ventricle. Am J Physiol Heart Circ Physiol 2007, 293(6):H3506-H3516. 10.1152/ajpheart.00757.2007, 2366895, 17906109.
12. Ashikaga H, Criscione JC, Omens JH, Covell JW, Ingels NB. Transmural lefr ventricular mechanics underlying torsional recoil during relaxation. Am J Physiol Heart Circ Physiol 2004, 286(2):H640-H647. 10.1152/ajpheart.00575.2003, 2954110, 14551052.
13. Schwertz DW, Beck JM, Kowalski JM, Ross JD. Sex differences in the response of rat heart ventricle to calcium. Biol Res Nurs 2004, 5(4):286-298. 10.1177/1099800403262615, 15068658.
14. Wang SN, Wyeth RP, Kennedy RH. Effects of gender on the sensitivity of rat cardiac muscle to extracellular Ca2+. Eur J Pharmacol 1998, 361(1):73-77. 10.1016/S0014-2999(98)00736-5, 9851543.
15. Curl CL, Delbridge LMD, Wendt IR. Sex differences in cardiac muscle responsiveness to Ca2+ and L-type Ca2+ channel modulation. Eur J Pharmacol 2008, 586(1-3):288-292.
16. Palmer BM, Wang Y, Teekakirikul P, et al. Myofilament mechanical performance is enhanced by R403Q myosin in mouse myocardium independent of sex. Am J Physiol 2008, 294(4):H1939-H1947.
17. Thawornkaiwong A, Pantharanontaga J, Wattanapermpool J. Hypersensitivity of myofilament response to Ca2+ in association with maladaptation of estrogen-deficient heart under diabetes complication. Am J Physiol 2007, 292(2):R844-R851.
18. Wattanapermpool J, Reiser PJ. Differential effects of ovariectomy on calcium activation of cardiac and soleus myofilaments. Am J Physiol 1999, 277(2):H467-H473.
19. Wattanapermpool J. Increase in calcium responsiveness of cardiac myofilament activation in ovariectomized rats. Life Sci 1998, 63(11):955-964. 10.1016/S0024-3205(98)00353-1, 9747896.
20. Curl CL, Delbridge LMD, Canny BJ, Wendt IR. Testosterone modulates cardiomyocyte Ca2+ handling and contractile function. Physiol Res 2009, 58(2):293-297.
21. Morano I, Arndt H, Gartner C, Ruegg JC. Skinned fibres of human atrium and ventricle: myosin isoenzymes and contractility. Circ Res 1988, 62:632-639. 10.1161/01.RES.62.3.632, 3342480.
22. Vasan RS, Larson MG, Levy D, Evans JC, Benjamin EJ. Distribution and categorization of echocardiographic measurements in relation to reference limits: the Framingham Heart Study: formulation of a height- and sex-specific classification and its prospective validation. Circulation 1997, 96(6):1863-1873. 10.1161/01.CIR.96.6.1863, 9323074.
23. Weber HH, Portzehl H. The transference of the muscle energy in the contraction cycle. Prog Biophys Mol Biol 1954, 4:60111.
24. Vahl CF, Lange R, Bauernschmitt R, Herold U, Tischmeyer K, Hagl S. Analyzing contractile responses in demembranized pig papillary muscle fibers: the influence of calcium, resting force and temperature. Thorac Cardiovasc Surgeon 1991, 39:329-337.
25. Di Bello V, Santini F, Di Cori A, Pucci A, Palagi C, Delle Donne MG, Fierabracci P, MArsili A, Talini E, Gianetti M, Biadi O, Balbarini A, Mariani M, Pinchera A. Obesity cardiomyopathy: is it reality? An ultrasonic tissue characterization study. J Am Soc Echocardiogr 2006, 19(8):1063-1071. 10.1016/j.echo.2006.03.033, 16880104.
26. Yamaguchi T, Kitamori K, Ichihara G, Suzuki Y, Ochiai M, Yamada Y, Tada-Oikawa S, Tsuchikura S, Yamori Y, Ichihara S. Serial changes in adipocytokines and cardiac dunction in a rat model of metabolic syndrome. Clin Exp Pharmacol Physiol 2013, 40(7):443-448. 10.1111/1440-1681.12107, 23659633.
27. Fares E, Howlett SE. Effect of age on cardiac excitstion-contraction coupling. Clin Exp Pharmacol Physiol 2010, 37(1):1-7. 10.1111/j.1440-1681.2009.05276.x, 19671063.
28. Look C, Morano I, Ehrhar-Bornstein M, Bornstein SR, Lamounier-Zepter V. Adipocyte-derived factors suppress heart contraction. Int J Obes (Lond) 2011, 35(1):84-90. 10.1038/ijo.2010.121, 20567241.
29. Strait J, Lakatta E. Aging-associated cardiovascular changes and their relationship to heart failure. Heart Fail Clin 2012, 8(1):143-164. 10.1016/j.hfc.2011.08.011, 3223374, 22108734.
30. Aurigemma GP, Gaasch WH. Gender differences in older patients with pressure-overload hypertrophy of the left ventricle. Cardiol 1995, 86(4):310-317.
31. Weinberg EO, Thienelt CD, Katz SE, BArtunek J, Tajima M, Rohrbach S, Douglas PS, Lorell Gender differences in molecular remodeling in pressure overload hypetrophy. J Am Coll Cardiol 1999, 34(1):264-273. 10.1016/S0735-1097(99)00165-5, 10400020, Lorell.
32. Montalvo C, Villar A, Merino D, Garcia R, Ares M, llano M, Cobo M, Nistal J, Hurlé Androgend contribute to sex differences in myocardial remodeling under pressure overload by mechanism involving TGF-ß. PLoS One 2012, 7(4):e35635. 10.1371/journal.pone.0035635, 3338422, 22558184, Hurlé.
33. Fang L, Gao XM, Moore XL, Kiriazis H, Su Y, Ming Z, Lim YL, Dart AM, Du XJ. Differences in inflammation, MMP activation and collagen damage account for gender difference in murine cardiac rupture following myocardial infarction. J Mol Cell Cardiol 2007, 43(5):535-544. 10.1016/j.yjmcc.2007.06.011, 17689559.
34. Lam C, Donal E, Kraigher-Krainer E, Vasan R. Epidemiology and clinical course of heart failure with preserved ejection fraction. Eur J Heart Fail 2011, 13(1):18-28. 10.1093/eurjhf/hfq121, 3003453, 20685685.