Quantification of cerebellar hemispheric purkinje cell linear density: 32 ET cases versus 16 controls

Movement Disorders

Volumn 28, Issue 13, 2013, Pages 1854-1859

  Louis, Elan D ^a,b,c   Babij, Rachel ^a   Lee, Michelle ^a   Cortés, Etty ^d   Vonsattel, Jean Paul G ^b,d  

^a Vagelos College of Physicians and Surgeons   (United States)

^b College of Physicians and Surgeons Columbia University ^*  (United States)

^c Department of Medicine   (United States)

^d NewYork Presbyterian Hospital   (United States)

Author keywords

Brain; Cerebellum; Essential tremor; Neurodegenerative; Pathology; Pathophysiology; Purkinje cell

Indexed keywords

POLYCLONAL ANTIBODY;

ADULT; AGED; ARTICLE; AUTOPSY; CELL DENSITY; CEREBELLUM; CLINICAL ARTICLE; CONTROLLED STUDY; ESSENTIAL TREMOR; FEMALE; HEMISPHERE; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; MALE; NERVE FIBER; NEUROLOGIST; NEUROPATHOLOGY; PATHOGENESIS; PRIORITY JOURNAL; PURKINJE CELL;

BRAIN; CEREBELLUM; ESSENTIAL TREMOR; NEURODEGENERATIVE; PATHOLOGY; PATHOPHYSIOLOGY; PURKINJE CELL;

AGED; AGED, 80 AND OVER; CALBINDIN 1; CELL COUNT; CEREBELLUM; ESSENTIAL TREMOR; FEMALE; FUNCTIONAL LATERALITY; HUMANS; MALE; PURKINJE CELLS; STATISTICS, NONPARAMETRIC;

EID: 84887628694     PISSN: 08853185     EISSN: 15318257     Source Type: Journal    
DOI: 10.1002/mds.25629     Document Type: Article

References (28)

1. Benito-Leon J, Bermejo-Pareja F, Morales JM, Vega S, Molina JA. Prevalence of essential tremor in three elderly populations of central Spain. Mov Disord. 2003;18:389-394.
2. Louis ED, Ferreira JJ. How common is the most common adult movement disorder? Update on the worldwide prevalence of essential tremor. Mov Disord. 2010;25:534-541.
3. Dogu O, Sevim S, Camdeviren H, et al. Prevalence of essential tremor: door-to-door neurologic exams in Mersin Province, Turkey. Neurology. 2003;61:1804-1806.
4. Benito-Leon J. Essential tremor: one of the most common neurodegenerative diseases? Neuroepidemiology. 2011;36:77-78.
5. Louis ED, Frucht SJ, Rios E. Intention tremor in essential tremor: Prevalence and association with disease duration. Mov Disord. 2009;24:626-627.
6. Louis ED, Shungu DC, Chan S, Mao X, Jurewicz EC, Watner D. Metabolic abnormality in the cerebellum in patients with essential tremor: a proton magnetic resonance spectroscopic imaging study. Neurosci Lett. 2002;333:17-20.
7. Kronenbuerger M, Konczak J, Ziegler W, et al. Balance and motor speech impairment in essential tremor. Cerebellum. 2009;8:389-398.
8. Cerasa A, Messina D, Nicoletti G, et al. Cerebellar atrophy in essential tremor using an automated segmentation method. Am J Neuroradiol. 2009;30:1240-1243.
9. Avanzino L, Bove M, Tacchino A, et al. Cerebellar involvement in timing accuracy of rhythmic finger movements in essential tremor. Eur J Neurosci. 2009;30:1971-1979.
10. Quattrone A, Cerasa A, Messina D, et al. Essential head tremor is associated with cerebellar vermis atrophy: a volumetric and voxel-based morphometry MR imaging study. Am J Neuroradiol. 2008;29:1692-1697.
11. Louis ED. Essential tremor: evolving clinicopathological concepts in an era of intensive post-mortem enquiry. Lancet Neurol. 2010;9:613-622.
12. Louis ED, Faust PL, Vonsattel JP, et al. Neuropathological changes in essential tremor: 33 cases compared with 21 controls. Brain. 2007;130:3297-3307.
13. Louis ED, Faust PL, Ma KJ, Yu M, Cortes E, Vonsattel JP. Torpedoes in the cerebellar vermis in essential tremor cases vs. controls. Cerebellum. 2011;10:812-819.
14. Yu M, Ma K, Faust PL, et al. Increased number of Purkinje cell dendritic swellings in essential tremor. Eur J Neurol. 2012;19:625-630.
15. Kuo SH, Erickson-Davis C, Gillman A, Faust PL, Vonsattel JP, Louis ED. Increased number of heterotopic Purkinje cells in essential tremor. J Neurol Neurosurg Psychiatry. 2011;82:1038-1040.
16. Erickson-Davis CR, Faust PL, Vonsattel JP, Gupta S, Honig LS, Louis ED. "Hairy baskets" associated with degenerative Purkinje cell changes in essential tremor. J Neuropathol Exp Neurol. 2010;69:262-271.
17. Louis ED, Vonsattel JP, Honig LS, et al. Essential tremor associated with pathologic changes in the cerebellum. Arch Neurol. 2006;63:1189-1193.
18. Axelrad JE, Louis ED, Honig LS, et al. Reduced purkinje cell number in essential tremor: a postmortem study. Arch Neurol. 2008;65:101-107.
19. Rajput AH, Robinson CA, Rajput ML, Robinson SL, Rajput A. Essential tremor is not dependent upon cerebellar Purkinje cell loss. Parkinsonism Relat Disord. 2012;18:626-628.
20. Louis ED, Faust PL, Vonsattel JP. Purkinje cell loss is a characteristic of essential tremor: Towards a more mature understanding of pathogenesis. Parkinsonism Relat Disord. 2012;18:1003-1004.
21. Louis ED, Borden S, Moskowitz CB. Essential tremor centralized brain repository: diagnostic validity and clinical characteristics of a highly selected group of essential tremor cases. Mov Disord. 2005;20:1361-1365.
22. Harasymiw JW, Bean P. Identification of heavy drinkers by using the early detection of alcohol consumption score. Alcohol Clin Exp Res. 2001;25:228-235.
23. Louis ED, Zheng W, Applegate L, Shi L, Factor-Litvak P. Blood harmane concentrations and dietary protein consumption in essential tremor. Neurology. 2005;65:391-396.
24. Braak H, Braak E. Diagnostic criteria for neuropathologic assessment of Alzheimer's disease. Neurobiol Aging. 1997;18(4 Suppl):S85-S88.
25. Braak H, Alafuzoff I, Arzberger T, Kretzschmar H, Del Tredici K. Staging of Alzheimer disease-associated neurofibrillary pathology using paraffin sections and immunocytochemistry. Acta Neuropathol. 2006;112:389-404.
26. Braak H, Del Tredici K, Rub U, de Vos RA, Jansen Steur EN, Braak E. Staging of brain pathology related to sporadic Parkinson's disease. Neurobiol Aging. 2003;24:197-211.
27. Mirra SS. The CERAD neuropathology protocol and consensus recommendations for the postmortem diagnosis of Alzheimer's disease: a commentary. Neurobiol Aging. 1997;18(4 Suppl):S91-S94.
28. Louis ED, Vonsattel JP, Honig LS, Ross GW, Lyons KE, Pahwa R. Neuropathologic findings in essential tremor. Neurology. 2006;66:1756-1759.