Association of dietary intake of folate, vitamin B6 and B12 and MTHFR genotype with breast cancer risk

Asian Pacific Journal of Cancer Prevention

Volumn 14, Issue 9, 2013, Pages 5189-5192

  Liu, Ying ^a   Zhou, Long Shu ^a   Xu, Xiao Ming ^a   Deng, Liang Qing ^a   Xiao, Qian Kun ^a  

^a GUANGZHOU MEDICAL UNIVERSITY   (China)

Author keywords

Breast cancer; Folate; MTHFR; Polymorphism; Vitamin

Indexed keywords

CYANOCOBALAMIN; FOLIC ACID; METHYLENETETRAHYDROFOLATE REDUCTASE (NADPH2); MTHFR PROTEIN, HUMAN; PYRIDOXINE;

ADULT; ASIAN CONTINENTAL ANCESTRY GROUP; BREAST NEOPLASMS; CASE CONTROL STUDY; CHINA; DIET; EATING; EPIDEMIOLOGY; FEMALE; GENETIC PREDISPOSITION; GENETICS; GENOTYPE; GENOTYPE ENVIRONMENT INTERACTION; HUMAN; MIDDLE AGED; PROTECTION; STATISTICS AND NUMERICAL DATA;

ADULT; ASIAN CONTINENTAL ANCESTRY GROUP; BREAST NEOPLASMS; CASE-CONTROL STUDIES; CHINA; DIET; EATING; FEMALE; FOLIC ACID; GENE-ENVIRONMENT INTERACTION; GENETIC PREDISPOSITION TO DISEASE; GENOTYPE; HUMANS; METHYLENETETRAHYDROFOLATE REDUCTASE (NADPH2); MIDDLE AGED; PROTECTIVE FACTORS; VITAMIN B 12; VITAMIN B 6;

EID: 84887574834     PISSN: 15137368     EISSN: 2476762X     Source Type: Journal    
DOI: 10.7314/APJCP.2013.14.9.5189     Document Type: Article

References (30)

1. Alshatwi AA (2010). Breast cancer risk, dietary intake, and methylenetetrahydrofolate reductase (MTHFR) single nucleotide polymorphisms. Food Chem Toxicol, 48, 1881-1885.
2. Akram M, Malik FA, Kayani MA (2012). Mutational analysis of the MTHFR gene in breast cancer patients of Pakistani population. Asian Pac J Cancer Prev, 13, 1599-1603.
3. de Cássia Carvalho Barbosa R, da Costa DM, Cordeiro DE, Vieira AP, Rabenhorst SH(2012). Interaction of MTHFR C677T and A1298C, and MTR A2756G gene polymorphisms in breast cancer risk in a population in Northeast Brazil. Anticancer Res, 32, 4805-11.
4. Chen J, Gammon MD, Chan W, Palomeque C, et al (2005). One-carbon metabolism, MTHFR polymorphisms, and risk of breast cancer. Cancer Res, 65, 1606-14.
5. Cho E, Holmes M, Hankinson SE, Willett WC (2007). Nutrients involved in one-carbon metabolism and risk of breast cancer among premenopausal women. Cancer Epidemiol Biomarkers Prev, 16, 2787-90.
6. Ergul E, Sazci A, Utkan Z, Canturk NZ (2003). Polymorphisms in the MTHFR gene are associated with breast cancer. Tumor Biol, 24, 286-290.
7. Gao CM, Kazuo T, Tang JH, et al (2009). MTHFR polymorphisms, dietary folate intake and risks to breast cancer. Zhonghua Yu Fang Yi Xue Za Zhi, 43, 576-80.
8. Gershoni-Baruch R, Dagan E, Israeli D, et al (2000). Association of the C677T polymorphism in the MTHFR gene with breast and/or ovarian cancer risk in Jewish women. Eur J Cancer, 36, 2313-6.
9. Hosseini M, Houshmand M, Ebrahimi A (2011). MTHFR polymorphisms and breast cancer risk. Arch Med Sci, 7, 134-7.
10. Islam T, Ito H, Sueta A, et al (2013). Alcohol and dietary folate intake and the risk of breast cancer: a case-control study in Japan. Eur J Cancer Prev, 22, 358-66.
11. Jiao Z, Li D (2013). Lack of association between MHTFR Glu429Ala polymorphism and breast cancer susceptibility: a systematic review and meta-analysis of 29 research studies. Tumour Biol, 34, 1225-33.
12. Kim YI (2006). Does a high folate intake increase the risk of breast cancer? Nutr Rev, 64, 468-75.
13. Larsson SC, Giovannucci E, Wolk A (2007). Folate and risk of breast cancer: a meta-analysis. J Natl Cancer Inst, 99, 64-76.
14. Lajin B, Alhaj Sakur A, Ghabreau L, Alachkar A (2012). Association of polymorphisms in one-carbon metabolizing genes with breast cancer risk in Syrian women. Tumour Biol, 33, 1133-9.
15. Lin J, Lee IM, Cook NR, et al (2008). Plasma folate, vitamin B-6, vitamin B-12, and risk of breast cancer in women. Am J Clin Nutr, 87, 734-43.
16. Matsubara K, Komatsu S, Oka T, Kato N (2003). Vitamin B6-mediated suppression of colon tumorigenesis, cell proliferation, and angiogenesis. J Nutr Biochem, 14, 246-50.
17. Maruti SS, Ulrich CM, Jupe ER, White E (2009). MTHFR C677T and postmenopausal breast cancer risk by intakes of one-carbon metabolism nutrients: a nested case-control study. Breast Cancer Res, 11, R91.
18. International Agency for Research on Cancer (2008). Globocan 2008, China. http://globocan.iarc.fr/factsheet.asp, IARC.
19. Qiu LX, Zhang J, Li WH, et al (2011). Lack of association between methylenetetrahydrofolate reductase gene A1298C polymorphism and breast cancer susceptibility. Mol Biol Rep, 38, 2295-9.
20. Szakacs G, Paterson JK, Booth-Genthe C, Gottesman MM (2006). Targeting multidrug resistance in cancer. Nat. Rev. Drug Discov, 5, 219-34.
21. Roberti A, La Sala D, Cinti C (2006). Multiple genetic and epigenetic interacting mechanisms contribute to clonally therapeutic prospective. J. Cell Physiol, 207, 571-81.
22. Rossi E, Hung J, Beilby JP, Knuiman MW, et al (2006). Folate levels and cancer morbidity and mortality: prospective cohort study from Busselton, Western Australia. Ann. Epidemiol, 16, 206-12.
23. Selhub J (2002). Folate, vitamin B12 and vitamin B6 and one-carbon metabolism. J Nutr Health Aging, 6, 39-42.
24. Semenza JC, Delfino RJ, Ziogas A, Anton-Culver H (2003). Breast cancer risk and methylenetetrahydrofolate reductase polymorphism. Breast Cancer Res. Treat, 77, 217-23.
25. Ulrich CM (2005). Nutrigenetics in cancer research-folate metabolism and colorectal cancer. J. Nutr, 135, 2698-702.
26. Xu X, Gammon MD, Wetmur JG, Bradshaw PT, et al (2008). B-vitamin intake, one-carbon metabolism, and survival in a population-based study of women with breast cancer. Cancer Epidemiol Biomarkers Prev, 17, 2109-16.
27. Yang D, Baumgartner RN, Slattery ML, et al (2013). Dietary intake of folate, B-vitamins and methionine and breast cancer risk among Hispanic and non-Hispanic white women. PLoS One, 8, e54495.
28. Yu L, Chen J (2012). Association of MTHFR Ala222Val (rs1801133) polymorphism and breast cancer susceptibility: An update meta-analysis based on 51 research studies. Diagn Pathol, 7, 171.
29. Vainer AS, Boiarskikh UA, Voronina EN, Selezneva IA, et al (2010). Polymorphic variants of folate metabolizing genes (C677T and A1298C MTHFR, C1420T SHMT1 and G1958A MTHFD) are not associated with the risk of breast cancer in West Siberian Region of Russia. Mol Biol (Mosk), 44, 816-23.
30. Wu XY, Ni J, Xu WJ, et al (2012). Interactions between MTHFR C677T-A1298C variants and folic acid deficiency affect breast cancer risk in a Chinese population. Asian Pac J Cancer Prev, 13, 2199-06.