Changes in physical performance in older women according to presence and treatment of diabetes mellitus

Journal of the American Geriatrics Society

Volumn 61, Issue 11, 2013, Pages 1872-1878

  Lee, Christine G ^a,b,c   Schwartz, Ann V ^d   Yaffe, Kristine ^d   Hillier, Teresa A ^c   Leblanc, Erin S ^c   Cawthon, Peggy M ^e  

^a PORTLAND VA MEDICAL CENTER   (United States)

^b OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

^c CENTER FOR HEALTH RESEARCH   (United States)

^d UNIVERSITY OF CALIFORNIA   (United States)

^e CALIFORNIA PACIFIC MEDICAL CENTER   (United States)

Author keywords

diabetes mellitus; elderly; insulin sensitizer; physical performance; walk speed

Indexed keywords

GLITAZONE DERIVATIVE; INSULIN SENSITIZING AGENT; METFORMIN;

AGED; ARTICLE; COMMUNITY LIVING; DIABETES MELLITUS; DIABETIC PATIENT; ELDERLY CARE; FEMALE; GRIP STRENGTH; HUMAN; LONGITUDINAL STUDY; MAJOR CLINICAL STUDY; PHYSICAL PERFORMANCE; PRESCRIPTION; UNITED STATES; WALKING SPEED;

DIABETES MELLITUS; ELDERLY; INSULIN SENSITIZER; PHYSICAL PERFORMANCE; WALK SPEED;

AGED; COHORT STUDIES; DIABETES MELLITUS; FEMALE; HAND STRENGTH; HUMANS; PROSPECTIVE STUDIES; WALKING;

EID: 84887509152     PISSN: 00028614     EISSN: 15325415     Source Type: Journal    
DOI: 10.1111/jgs.12502     Document Type: Article

References (37)

1. Cowie CC, Rust KF, Ford ES, et al. Full accounting of diabetes and pre-diabetes in the U.S. population in 1988-1994 and 2005-2006. Diabetes Care 2009; 32: 287-294.
2. Gregg EW, Mangione CM, Cauley JA, et al. Diabetes and incidence of functional disability in older women. Diabetes Care 2002; 25: 61-67.
3. Schwartz AV, Hillier TA, Sellmeyer DE, et al. Older women with diabetes have a higher risk of falls: A prospective study. Diabetes Care 2002; 25: 1749-1754.
4. Kirkman MS, Briscoe VJ, Clark N, et al. Diabetes in older adults. Diabetes Care 2012; 35: 2650-2664.
5. Park SW, Goodpaster BH, Strotmeyer ES, et al. Accelerated loss of skeletal muscle strength in older adults with type 2 diabetes: The Health, Aging, and Body Composition Study. Diabetes Care 2007; 30: 1507-1512.
6. Park SW, Goodpaster BH, Lee JS, et al. Excessive loss of skeletal muscle mass in older adults with type 2 diabetes. Diabetes Care 2009; 32: 1993-1997.
7. Barzilay JI, Cotsonis GA, Walston J, et al. Insulin resistance is associated with decreased quadriceps muscle strength in nondiabetic adults aged >or=70 years. Diabetes Care 2009; 32: 736-738.
8. Kuo CK, Lin LY, Yu YH, et al. Inverse association between insulin resistance and gait speed in nondiabetic older men: Results from the U.S. National Health and Nutrition Examination Survey (NHANES) 1999-2002. BMC Geriatr 2009; 9: 49.
9. Widen EI, Eriksson JG, Groop LC,. Metformin normalizes nonoxidative glucose metabolism in insulin-resistant normoglycemic first-degree relatives of patients with NIDDM. Diabetes 1992; 41: 354-358.
10. Maggs DG, Buchanan TA, Burant CF, et al. Metabolic effects of troglitazone monotherapy in type 2 diabetes mellitus. A randomized, double-blind, placebo-controlled trial. Ann Intern Med 1998; 128: 176-185.
11. Narkar VA, Downes M, Yu RT, et al. AMPK and PPARdelta agonists are exercise mimetics. Cell 2008; 134: 405-415.
12. Cummings SR, Black DM, Nevitt MC, et al. Appendicular bone density and age predict hip fracture in women. The Study of Osteoporotic Fractures Research Group. JAMA 1990; 263: 665-668.
13. Pahor M, Chrischilles EA, Guralnik JM, et al. Drug data coding and analysis in epidemiologic studies. Eur J Epidemiol 1994; 10: 405-411.
14. Gregg EW, Yaffe K, Cauley JA, et al. Is diabetes associated with cognitive impairment and cognitive decline among older women? Study of Osteoporotic Fractures Research Group. Arch Intern Med 2000; 160: 174-180.
15. Yaffe K, Blackwell T, Kanaya AM, et al. Diabetes, impaired fasting glucose, and development of cognitive impairment in older women. Neurology 2004; 63: 658-663.
16. Strotmeyer ES, de Rekeneire N, Schwartz AV, et al. The relationship of reduced peripheral nerve function and diabetes with physical performance in older white and black adults: The Health, Aging, and Body Composition (health ABC) Study. Diabetes Care 2008; 31: 1767-1772.
17. Onder G, Penninx BW, Ferrucci L, et al. Measures of physical performance and risk for progressive and catastrophic disability: Results from the Women's Health and Aging Study. J Gerontol A Biol Sci Med Sci 2005; 60A: 74-79.
18. Dube JJ, Amati F, Stefanovic-Racic M, et al. Exercise-induced alterations in intramyocellular lipids and insulin resistance: The athlete's paradox revisited. Am J Physiol Endocrinol Metab 2008; 294: E882-E888.
19. Donner T, Munoz M,. Update on insulin therapy for type 2 diabetes. J Clin Endocrinol Metab 2012; 97: 1405-1413.
20. Fleegler FM, Rogers KD, Drash A, et al. Age, sex, and season of onset of juvenile diabetes in different geographic areas. Pediatrics 1979; 63: 374-379.
21. Lee CG, Boyko EJ, Barrett-Connor E, et al. Insulin sensitizers may attenuate lean mass loss in older men with diabetes. Diabetes Care 2011; 34: 2381-2386.
22. Inzucchi SE, Maggs DG, Spollett GR, et al. Efficacy and metabolic effects of metformin and troglitazone in type II diabetes mellitus. N Engl J Med 1998; 338: 867-872.
23. Craft S,. Insulin resistance and Alzheimer's disease pathogenesis: Potential mechanisms and implications for treatment. Curr Alzheimer Res 2007; 4: 147-152.
24. Clerk LH, Vincent MA, Jahn LA, et al. Obesity blunts insulin-mediated microvascular recruitment in human forearm muscle. Diabetes 2006; 55: 1436-1442.
25. Bruehl H, Sweat V, Hassenstab J, et al. Cognitive impairment in nondiabetic middle-aged and older adults is associated with insulin resistance. J Clin Exp Neuropsychol 2010; 32: 487-493.
26. Abbatecola AM, Lattanzio F, Molinari AM, et al. Rosiglitazone and cognitive stability in older individuals with type 2 diabetes and mild cognitive impairment. Diabetes Care 2010; 33: 1706-1711.
27. Holman RR, Paul SK, Bethel MA, et al. Ten-year follow-up of intensive glucose control in type 2 diabetes. N Engl J Med 2008; 359: 1577-1589.
28. Coggan AR, Spina RJ, King DS, et al. Skeletal muscle adaptations to endurance training in 60- to 70-yr-old men and women. J Appl Physiol 1992; 72: 1780-1786.
29. Musi N, Hirshman MF, Nygren J, et al. Metformin increases AMP-activated protein kinase activity in skeletal muscle of subjects with type 2 diabetes. Diabetes 2002; 51: 2074-2081.
30. Suwa M, Egashira T, Nakano H, et al. Metformin increases the PGC-1 alpha protein and oxidative enzyme activities possibly via AMPK phosphorylation in skeletal muscle in vivo. J Appl Physiol 2006; 101: 1685-1692.
31. Smith AC, Bruce CR, Dyck DJ,. AMP kinase activation with AICAR simultaneously increases fatty acid and glucose oxidation in resting rat soleus muscle. J Physiol 2005; 565 (Pt 2): 537-546.
32. Suwa M, Nakano H, Kumagai S,. Effects of chronic AICAR treatment on fiber composition, enzyme activity, UCP3, and PGC-1 in rat muscles. J Appl Physiol 2003; 95: 960-968.
33. Harris MI, Flegal KM, Cowie CC, et al. Prevalence of diabetes, impaired fasting glucose, and impaired glucose tolerance in U.S. adults. The Third National Health and Nutrition Examination Survey, 1988-1994. Diabetes Care 1998; 21: 518-524.
34. Charlson ME, Pompei P, Ales KL, et al. A new method of classifying prognostic comorbidity in longitudinal studies: Development and validation. J Chronic Dis 1987; 40: 373-383.
35. Volpato S, Maraldi C, Fellin R,. Type 2 diabetes and risk for functional decline and disability in older persons. Curr Diabetes Rev 2010; 6: 134-143.
36. Chiu CJ, Wray LA,. Physical disability trajectories in older Americans with and without diabetes: The role of age, gender, race or ethnicity, and education. Gerontologist 2011; 51: 51-63.
37. Lu FP, Lin KP, Kuo HK,. Diabetes and the risk of multi-system aging phenotypes: A systematic review and meta-analysis. PLoS ONE 2009; 4: e4144.