Kidney and Bladder Outcomes in Children with Hemorrhagic Cystitis and BK Virus Infection after Allogeneic Hematopoietic Stem Cell Transplantation

Biology of Blood and Marrow Transplantation

Volumn 19, Issue 12, 2013, Pages 1702-1707

  Oshrine, Benjamin ^a   Bunin, Nancy ^a   Li, Yimei ^a   Furth, Susan ^a,b   Laskin, Benjamin L ^a  

^a CHILDREN S HOSPITAL OF PHILADELPHIA   (United States)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

BK virus; Hemorrhagic cystitis; Pediatrics; Transplantation

Indexed keywords

ACICLOVIR; ALEMTUZUMAB; AMOXICILLIN; BUSULFAN; CALCINEURIN INHIBITOR; CIDOFOVIR; CORTICOSTEROID; CYCLOPHOSPHAMIDE; CYCLOSPORIN; FLUCONAZOLE; FLUDARABINE; FOSCARNET; GENTAMICIN; IMMUNOGLOBULIN; MELPHALAN; METHOTREXATE; MYCOPHENOLIC ACID 2 MORPHOLINOETHYL ESTER; TACROLIMUS; THIOTEPA; THYMOCYTE ANTIBODY;

ALLOGENEIC HEMATOPOIETIC STEM CELL TRANSPLANTATION; ARTICLE; BK VIRUS INFECTION; BLADDER CATHETERIZATION; BLADDER INJURY; BLOODSTREAM INFECTION; CHEMOPROPHYLAXIS; CHILD; CHILD DEATH; CHILDHOOD DISEASE; CHILDHOOD MORTALITY; CREATININE BLOOD LEVEL; CYTOMEGALOVIRUS INFECTION; DISEASE ASSOCIATION; FEMALE; GLOMERULUS FILTRATION RATE; GRAFT RECIPIENT; GRAFT VERSUS HOST REACTION; HEMATOLOGIC MALIGNANCY; HEMORRHAGIC CYSTITIS; HERPES SIMPLEX; HERPES ZOSTER; HUMAN; INFECTION PREVENTION; KIDNEY INJURY; LOW DRUG DOSE; MAJOR CLINICAL STUDY; MALE; MULTIMODALITY CANCER THERAPY; MYELOABLATIVE CONDITIONING; OUTCOME ASSESSMENT; PEDIATRIC SURGERY; POLYMERASE CHAIN REACTION; POSTOPERATIVE COMPLICATION; REDUCED INTENSITY CONDITIONING; RENAL REPLACEMENT THERAPY; RETROSPECTIVE STUDY; RISK FACTOR; SCHOOL CHILD; T CELL DEPLETION; URINARY TRACT INFECTION; VIREMIA; WHOLE BODY RADIATION;

BK VIRUS; HEMORRHAGIC CYSTITIS; PEDIATRICS; TRANSPLANTATION;

ADOLESCENT; BK VIRUS; CHILD; CHILD, PRESCHOOL; CYSTITIS; FEMALE; HEMATOPOIETIC STEM CELL TRANSPLANTATION; HUMANS; KIDNEY DISEASES; MALE; TRANSPLANTATION CONDITIONING; TRANSPLANTATION, AUTOLOGOUS; TREATMENT OUTCOME; URINARY BLADDER DISEASES; VIRAL LOAD;

EID: 84887508022     PISSN: 10838791     EISSN: 15236536     Source Type: Journal    
DOI: 10.1016/j.bbmt.2013.09.007     Document Type: Article

References (28)

1. Knowles W.A., Pipkin P., Andrews N., et al. Population-based study of antibody to the human polyomaviruses BKV and JCV and the simian polyomavirus SV40. JMed Virol 2003, 71:115-123.
2. Ramos E., Drachenberg C.B., Wali R., Hirsch H.H. The decade of polyomavirus BK-associated nephropathy: state of affairs. Transplantation 2009, 87:621-630.
3. Dropulic L.K., Jones R.J. Polyomavirus BK infection in blood and marrow transplant recipients. Bone Marrow Transplant 2008, 41:11-18.
4. Hirsch H.H., Knowles W., Dickenmann M., et al. Prospective study of polyomavirus type BK replication and nephropathy in renal-transplant recipients. NEngl J Med 2002, 347:488-496.
5. Arthur R.R., Shah K.V., Baust S.J., et al. Association of BK viruria with hemorrhagic cystitis in recipients of bone marrow transplants. NEngl J Med 1986, 315:230-234.
6. Apperley J.F., Rice S.J., Bishop J.A., et al. Late-onset hemorrhagic cystitis associated with urinary excretion of polyomaviruses after bone marrow transplantation. Transplantation 1987, 43:108-112.
7. Gaziev J., Paba P., Miano R., et al. Late-onset hemorrhagic cystitis in children after hematopoietic stem cell transplantation for thalassemia and sickle cell anemia: a prospective evaluation of polyoma (BK) virus infection and treatment with cidofovir. Biol Blood Marrow Transplant 2010, 16:662-671.
8. Gorczynska E., Turkiewicz D., Rybka K., et al. Incidence, clinical outcome, and management of virus-induced hemorrhagic cystitis in children and adolescents after allogeneic hematopoietic cell transplantation. Biol Blood Marrow Transplant 2005, 11:797-804.
9. Cesaro S., Facchin C., Tridello G., et al. Aprospective study of BK-virus-associated haemorrhagic cystitis in paediatric patients undergoing allogeneic haematopoietic stem cell transplantation. Bone Marrow Transplant 2008, 41:363-370.
10. Hingorani S. Chronic kidney disease in long-term survivors of hematopoietic cell transplantation: epidemiology, pathogenesis, and treatment. JAm Soc Nephrol 2006, 17:1995-2005.
11. Raval M., Gulbis A., Bollard C., et al. Evaluation and management ofBKvirus-associated nephropathy following allogeneic hematopoietic cell transplantation. Biol Blood Marrow Transplant 2011, 17:1589-1593.
12. Verghese P.S., Finn L.S., Englund J.A., et al. BK nephropathy in pediatric hematopoietic stem cell transplant recipients. Pediatr Transplant 2009, 13:913-918.
13. Lekakis L.J., Macrinici V., Baraboutis I.G., et al. BK virus nephropathy after allogeneic stem cell transplantation: a case report and literature review. Am J Hematol 2009, 84:243-246.
14. Limaye A.P., Smith K.D., Cook L., et al. Polyomavirus nephropathy in native kidneys of non-renal transplant recipients. Am J Transplant 2005, 5:614-620.
15. O'Donnell P.H., Swanson K., Josephson M.A., et al. BK virus infection is associated with hematuria and renal impairment in recipients of allogeneic hematopoetic stem cell transplants. Biol Blood Marrow Transplant 2009, 15:1038-1048.
16. Haines H.L., Laskin B.L., Goebel J., et al. Blood, and not urine, BK viral load predicts renal outcome in children with hemorrhagic cystitis following hematopoietic stem cell transplantation. Biol Blood Marrow Transplant 2011, 17:1512-1519.
17. Lee Y.J., Chung D., Xiao K., et al. Adenovirus viremia and disease: comparison of T cell-depleted and conventional hematopoietic stem cell transplantation recipients from a single institution. Biol Blood Marrow Transplant 2013, 19:387-392.
18. Schwartz G.J., Munoz A., Schneider M.F., et al. New equations to estimate GFR in children with CKD. JAm Soc Nephrol 2009, 20:629-637.
19. Bedi A., Miller C.B., Hanson J.L., et al. Association of BK virus with failure of prophylaxis against hemorrhagic cystitis following bone marrow transplantation. JClin Oncol 1995, 13:1103-1109.
20. Droller M.J., Saral R., Santos G. Prevention of cyclophosphamide-induced hemorrhagic cystitis. Urology 1982, 20:256-258.
21. Lamoth F., Pascual M., Erard V., et al. Low-dose cidofovir for the treatment of polyomavirus-associated nephropathy: two case reports and review of the literature. Antivir Ther 2008, 13:1001-1009.
22. Mori Y., Miyamoto T., Kato K., et al. Different risk factors related to adenovirus- or BK virus-associated hemorrhagic cystitis following allogeneic stem cell transplantation. Biol Blood Marrow Transplant 2012, 18:458-465.
23. Ferrara J.L., Levine J.E., Reddy P., Holler E. Graft-versus-host disease. Lancet 2009, 373:1550-1561.
24. Laskin B.L., Denburg M., Furth S., et al. BK viremia precedes hemorrhagic cystitis in children undergoing allogeneic hematopoietic stem cell transplantation. Biol Blood Marrow Transplant 2013, 19:1175-1182.
25. Erard V., Kim H.W., Corey L., et al. BK DNA viral load in plasma: evidence for an association with hemorrhagic cystitis in allogeneic hematopoietic cell transplant recipients. Blood 2005, 106:1130-1132.
26. Laskin B.L., Nehus E., Goebel J., et al. Cystatin C-estimated glomerular filtration rate in pediatric autologous hematopoietic stem cell transplantation. Biol Blood Marrow Transplant 2012, 18:1745-1752.
27. Inker L.A., Schmid C.H., Tighiouart H., et al. Estimating glomerular filtration rate from serum creatinine and cystatin C. NEngl J Med 2012, 367:20-29.
28. Bia M., Adey D.B., Bloom R.D., et al. KDOQI US commentary on the 2009 KDIGO clinical practice guideline for the care of kidney transplant recipients. Am J Kidney Dis 2010, 56:189-218.