The liver X receptor pathway is highly upregulated in rheumatoid arthritis synovial Macrophages and potentiates TLR-driven cytokine release

Annals of the Rheumatic Diseases

Volumn 72, Issue 12, 2013, Pages 2024-2031

  Asquith, Darren Lee ^a   Ballantine, Lucy E ^b   Nijjar, Jagtar Singh ^a   Makdasy, Manhal Khuder ^a   Patel, Sabina ^c   Wright, Pamela B ^a   Reilly, James H ^a   Kerr, Shauna ^a   Kurowska Stolarska, Mariola ^a   Gracie, J Alastair ^a   McInnes, Iain B ^a  

^a UNIVERSITY OF GLASGOW   (United Kingdom)

^b UNIVERSITY OF LIVERPOOL   (United Kingdom)

^c GLAXOSMITHKLINE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CHOLESTEROL; CYTOKINE; LIVER X RECEPTOR; LIVER X RECEPTOR ALPHA; TOLL LIKE RECEPTOR; TRANSCRIPTOME; TUMOR NECROSIS FACTOR ALPHA;

ARTICLE; CELL DIFFERENTIATION; CLINICAL ARTICLE; COMPUTER MODEL; CONTROLLED STUDY; CYTOKINE RELEASE; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOFLUORESCENCE; MACROPHAGE; MICROARRAY ANALYSIS; MONOCYTE; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; RHEUMATOID ARTHRITIS; SYNOVIAL FLUID; SYNOVIUM; UPREGULATION;

CYTOKINES; INFLAMMATION; RHEUMATOID ARTHRITIS; SYNOVIAL FLUID;

AGED; ARTHRITIS, RHEUMATOID; CELL DIFFERENTIATION; CYTOKINES; FEMALE; GENE EXPRESSION PROFILING; HUMANS; MACROPHAGES; MALE; MIDDLE AGED; MONOCYTES; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; ORPHAN NUCLEAR RECEPTORS; SIGNAL TRANSDUCTION; SYNOVIAL FLUID; SYNOVITIS; TOLL-LIKE RECEPTORS; TUMOR NECROSIS FACTOR-ALPHA; UP-REGULATION;

EID: 84887451261     PISSN: 00034967     EISSN: 14682060     Source Type: Journal    
DOI: 10.1136/annrheumdis-2012-202872     Document Type: Article

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