Preventive inositol hexaphosphate extracted from rice bran inhibits colorectal cancer through involvement of Wnt/β -catenin and COX-2 pathways

BioMed Research International

Volumn 2013, Issue , 2013, Pages

  Shafie, Nurul Husna ^a   Mohd Esa, Norhaizan ^a   Ithnin, Hairuszah ^a   Md Akim, Abdah ^a   Saad, Norazalina ^a   Pandurangan, Ashok Kumar ^a  

^a UNIVERSITY PUTRA MALAYSIA   (Malaysia)

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; AZOXYMETHANE; BETA CATENIN; CYCLOOXYGENASE 2; PHYTIC ACID; WNT PROTEIN; PTGS2 PROTEIN, RAT; TUMOR PROTEIN;

ABERRANT CRYPT FOCUS; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BODY WEIGHT; CARCINOGENESIS; COLON ADENOCARCINOMA; COLON ADENOMA; COLON CARCINOGENESIS; COLORECTAL CANCER; CONTROLLED STUDY; INVASIVE CARCINOMA; MALE; NONHUMAN; POLYP; PROTEIN EXPRESSION; RAT; REAL TIME POLYMERASE CHAIN REACTION; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; RICE BRAN; TREATMENT DURATION; WESTERN BLOTTING; WNT SIGNALING PATHWAY; ANIMAL; CHEMICALLY INDUCED DISORDER; CHEMISTRY; COLORECTAL TUMOR; DIETARY FIBER; DRUG ANTAGONISM; DRUG EFFECT; EXPERIMENTAL NEOPLASM; ISOLATION AND PURIFICATION; METABOLISM; PATHOLOGY; RICE; SPRAGUE DAWLEY RAT;

ANIMALS; ANTINEOPLASTIC AGENTS; BETA CATENIN; COLORECTAL NEOPLASMS; CYCLOOXYGENASE 2; DIETARY FIBER; MALE; NEOPLASM PROTEINS; NEOPLASMS, EXPERIMENTAL; ORYZA SATIVA; PHYTIC ACID; RATS; RATS, SPRAGUE-DAWLEY; WNT SIGNALING PATHWAY;

EID: 84887444153     PISSN: 23146133     EISSN: 23146141     Source Type: Journal    
DOI: 10.1155/2013/681027     Document Type: Article

References (50)

1. 6: a novel anti-cancer agent. Life Sciences 1997 61 4 343 354 2-s2.0-0030612467 10.1016/S0024-3205(97)00092-1 (Pubitemid 27305571)
2. Schlemmer U., Frølich W., Prieto R. M., Grases F., Phytate in foods and significance for humans: food sources, intake, processing, bioavailability, protective role and analysis. Molecular Nutrition and Food Research 2009 53 2 330 375 2-s2.0-70349987101 10.1002/mnfr.200900099
3. 6 and inositol. Nutrition and Cancer 2006 55 2 109 125 2-s2.0-33750846875 10.1207/s15327914nc5502-1 (Pubitemid 44719624)
4. Norhaizan M. E., Ng S. K., Norashareena M. S., Abdah M. A., Antioxidant and cytotoxicity effect of rice bran phytic acid as an anticancer agent on ovarian, breast and liver cancer cell lines. Malaysian Journal of Nutrition 2011 17 3 367 375
5. Jariwalla R. J., Rice-bran products: phytonutrients with potential applications in preventive and clinical medicine. Drugs under Experimental and Clinical Research 2001 27 1 17 26 2-s2.0-0035102946 (Pubitemid 32215892)
6. 6 in cancer therapy: past, present and future. Current Cancer Therapy Reviews 2010 6 1 1 12 2-s2.0-77949883130 10.2174/157339410790596443
7. Singh R. P., Sharma G., Mailikarjuna G. U., Dhanalakshmi S., Agarwal C., Agarwal R., In vivo suppression of hormone-refractory prostate cancer growth by inositol hexaphosphate: induction of insulin-like growth factor binding protein-3 and inhibition of vascular endothelial growth factor. Clinical Cancer Research 2004 10 1 I 244 250 2-s2.0-1642453720 10.1158/1078-0432.CCR-1080-3 (Pubitemid 38114186)
8. Singh R. P., Agarwal R., Prostate cancer and inositol hexaphosphate: efficacy and mechanisms. Anticancer Research 2005 25 4 2891 2904 2-s2.0-22944459874 (Pubitemid 41044678)
9. Norazalina S., Norhaizan M. E., Hairuszah I., Norashareena M. S., Anticarcinogenic efficacy of phytic acid extracted from rice bran on azoxymethane-induced colon carcinogenesis in rats. Experimental and Toxicologic Pathology 2010 62 3 259 268 2-s2.0-77952890136 10.1016/j.etp.2009.04.002
10. Jemal A., Bray F., Center M. M., Ferlay J., Ward E., Forman D., Global cancer statistics. CA Cancer Journal for Clinicians 2011 61 2 69 90 2-s2.0-79952232216 10.3322/caac.20107
11. Fearon E. R., Vogelstein B., A genetic model for colorectal tumorigenesis. Cell 1990 61 5 759 767 2-s2.0-0025312728 10.1016/0092-8674(90) 90186-I (Pubitemid 20185636)
12. Krzystyniak K. L., Current strategies for anticancer chemoprevention and chemoprotection. Acta Poloniae Pharmaceutica 2002 59 6 473 478 2-s2.0-0036870839 (Pubitemid 36322600)
13. Rajamanickam S., Agarwal R., Natural products and colon cancer: current status and future prospects. Drug Development Research 2008 69 7 460 471 2-s2.0-58149240953 10.1002/ddr.20276
14. Spychalski M., Dziki L., Dziki A., Chemoprevention of colorectal cancer: a new target needed? Colorectal Disease 2007 9 5 397 401 2-s2.0-34248641697 10.1111/j.1463-1318.2006.01166.x (Pubitemid 46773627)
15. Luu H. H., Zhang R., Haydon R. C., Rayburn E., Kang Q., Si W., Park J. K., Wang H., Peng Y., Jiang W., He T. C., Wnt/ β -catenin signaling pathway as novel cancer drug targets. Current Cancer Drug Targets 2004 4 8 653 671 2-s2.0-19944403876 10.2174/1568009043332709 (Pubitemid 40013572)
16. Kargman S. L., O'Neill G. P., Vickers P. J., Evans J. F., Mancini J. A., Jothy S., Expression of prostaglandin G/H synthase-1 and -2 protein in human colon cancer. Cancer Research 1995 55 12 2556 2559 2-s2.0-0029008617
17. Sano H., Kawahito Y., Wilder R. L., Hashiramoto A., Mukai S., Asai K., Kimura S., Kato H., Kondo M., Hla T., Expression of cyclooxygenase-1 and -2 in human colorectal cancer. Cancer Research 1995 55 17 3785 3789 2-s2.0-0029117472
18. Reddy B. S., Hirose Y., Cohen L. A., Simi B., Cooma I., Rao C. V., Preventive potential of wheat bran fractions against experimental colon carcinogenesis: implications for human colon cancer prevention. Cancer Research 2000 60 17 4792 4797 2-s2.0-0034282791
19. Lala G., Malik M., Zhao C., He J., Kwon Y., Giusti M. M., Magnuson B. A., Anthocyanin-rich extracts inhibit multiple biomarkers of colon cancer in rats. Nutrition and Cancer 2006 54 1 84 93 2-s2.0-33746544149 10.1207/s15327914nc5401- 10 (Pubitemid 44141339)
20. Bakhle Y. S., Cox-2 and cancer: a new approach to an old problem. British Journal of Pharmacology 2001 134 6 1137 1150 2-s2.0-0035185156 (Pubitemid 33097242)
21. Ramezanzadeh F. M., Rao R. M., Prinyawiwatkul W., Marshall W. E., Windhauser M., Effects of microwave heat, packaging, and storage temperature on fatty acid and proximate compositions in rice bran. Journal of Agricultural and Food Chemistry 2000 48 2 464 467 2-s2.0-0034005007 10.1021/jf9909609 (Pubitemid 30120383)
22. Zullaikah S., Melwita E., Ju Y. H., Isolation of oryzanol from crude rice bran oil. Bioresource Technology 2009 100 1 299 302 2-s2.0-51349145080 10.1016/j.biortech.2008.06.008
23. Norazalina S., Norhaizan M. E., Hairuszah I., Nurul Husna S., Optimization of optimum condition for phytic acid extraction from rice bran. African Journal of Plant Sciences 2011 5 168 175
24. Camire A. L., Clydesdale F. M., Analysis of phytic acid in foods by HPLC. Journal of Food Sciences 1982 47 575 578
25. Bird R. P., Hanaucek M., Walaszek Z., Aberrant crypt foci to study cancer preventive agents in the colon. Tumor Marker Protocol 1998 New Jersey, NJ, USA Human Press 465 474
26. Singh R. P., Sharma G., Mailikarjuna G. U., Dhanalakshmi S., Agarwal C., Agarwal R., In vivo suppression of hormone-refractory prostate cancer growth by inositol hexaphosphate: induction of insulin-like growth factor binding protein-3 and inhibition of vascular endothelial growth factor. Clinical Cancer Research 2004 10 1 I 244 250 2-s2.0-1642453720 10.1158/1078-0432.CCR-1080-3 (Pubitemid 38114186)
27. Cappell M. S., From colonic polyps to colon cancer: pathophysiology, clinical presentation, screening and colonoscopic therapy. Minerva Gastroenterologica e Dietologica 2007 53 4 351 373 2-s2.0-38649123979 (Pubitemid 351169829)
28. Jen J., Powell S. M., Papadopoulos N., Smith K. J., Hamilton S. R., Vogelstein B., Kinzler K. W., Molecular determinations on aberrant crypt foci from human colons. Cancer Research 1994 54 5527 5530
29. Alfin-Slater R. B., Kritchevsky D., Cancer and Nutrition New York, NY, USA Plenum Press
30. Ullah A., Shamsuddin A. M., Dose-dependent inhibition of large intestinal cancer by inositol hexaphosphate in F344 rats. Carcinogenesis 1990 11 12 2219 2222 2-s2.0-0025612325
31. Pretlow T. P., O'Riordan M. A., Pretlow T. G., Stellato T. A., Aberrant crypts in human colonic mucosa: putative preneoplastic lesions. Journal of Cellular Biochemistry Supplement 1992 16 55 62 2-s2.0-0027023015
32. 6) induces growth inhibition, cell cycle arrest and apoptosis on human colorectal adenocarcinoma cells. Journal of Medicinal Plant Research 2010 4 21 2283 2289 2-s2.0-78650529785
33. Norazalina S., Norhaizan M. E., Hairuszah I., Sabariah A. R., Husna S. N., Norsharina I., Antiproliferation and apoptosis induction of phytic acid in hepatocellular carcinoma (HEPG2) cell lines. African Journal of Biotechnology 2011 10 73 16646 16653 2-s2.0-81855218977 10.5897/AJB11.699
34. Powell S. M., Zilz N., Beazer-Barclay Y., Bryan T. M., Hamilton S. R., Thibodeau S. N., Vogelstein B., Kinzler K. W., APC mutations occur early during colorectal tumorigenesis. Nature 1992 359 6392 235 237 2-s2.0-0026630266 10.1038/359235a0
35. Polakis P., The adenomatous polyposis coil (APC) tumor suppressor. Biochimica et Biophysica Acta 1997 1332 3 F127 F147 2-s2.0-0031557898 10.1016/S0304-419X(97)00008-5 (Pubitemid 27272621)
36. Takahashi M., Fukuda K., Sugimura T., Wakabayashi K., β -catenin is frequently mutated and demonstrates altered cellular location in azoxymethane-induced rat colon tumors. Cancer Research 1998 58 1 42 46 2-s2.0-0031984227 (Pubitemid 28027714)
37. Aberle H., Bauer A., Stappert J., Kispert A., Kemler R., β -catenin is a target for the ubiquitin-proteasome pathway. EMBO Journal 1997 16 13 3797 3804 2-s2.0-0030978351 10.1093/emboj/16.13.3797 (Pubitemid 27280995)
38. Morin P. J., Sparks A. B., Korinek V., Barker N., Clevers H., Vogelstein B., Kinzler K. W., Activation of β -catenin-Tcf signaling in colon cancer by mutations in β -catenin or APC. Science 1997 275 5307 1787 1790 2-s2.0-0030949463 10.1126/science.275.5307.1787 (Pubitemid 27136715)
39. Molenaar M., van de Wetering M., Oosterwegel M., Peterson-Maduro J., Godsave S., Korinek V., Roose J., Destrée O., Clevers H., XTcf-3 transcription factor mediates β -catenin-induced axis formation in xenopus embryos. Cell 1996 86 3 391 399 2-s2.0-0001003110 10.1016/S0092-8674(00)80112-9 (Pubitemid 26272079)
40. Behrens J., Von Kries J. P., Kühl M., Bruhn L., Wedlich D., Grosschedl R., Birchmeier W., Functional interaction of β -catenin with the transcription factor LEF-1. Nature 1996 382 6592 638 642 2-s2.0-0029781509 10.1038/382638a0 (Pubitemid 26268958)
41. He T. C., Sparks A. B., Rago C., Hermeking H., Zawel L., Da Costa L. T., Morin P. J., Vogelstein B., Kinzler K. W., Identification of c-MYC as a target of the APC pathway. Science 1998 281 5382 1509 1512 2-s2.0-0032483439 10.1126/science.281.5382.1509 (Pubitemid 28425575)
42. Tetsu O., McCormick F., β -catenin regulates expression of cyclin D1 in colon carcinoma cells. Nature 1999 398 6726 422 426 2-s2.0-0033119801 10.1038/18884 (Pubitemid 29180374)
43. Ashokkumar P., Sudhandiran G., Luteolin inhibits cell proliferation during Azoxymethane-induced experimental colon carcinogenesis via Wnt/ β -catenin pathway. Investigational New Drugs 2011 29 2 273 284 2-s2.0-79957473480 10.1007/s10637-009-9359-9
44. Pandurangan A. K., Dharmalingam P., Ananda Sadagopan S. K., Luteolin induces growth arrest in colon cancer cells through involvement of Wnt/ β -catenin/GSK-3 β Journal of Environmental Pathology, Toxicology and Oncology 2013 32 2 131 139 10.1615/JEnvironPatholToxicolOncol.2013006793
45. Kumar A., Pandurangan A. K., Lu F., Fyrst H., Zhang M., Byun H. S., Bittman R., Saba J. D., Chemopreventive sphingadienes downregulate wnt signaling via a PP2A/Akt/GSK3 β pathway in colon cancer. Carcinogenesis 2012 33 9 1726 1735 10.1093/carcin/bgs174
46. Norazalina S., Norhaizan M. E., Hairuszah I., Suppression of β -catenin and cyclooxygenase-2 expression and cell proliferation in azoxymethane-induced colonic cancer in rats by rice bran phytic acid (PA). Asian Pacific Journal of Cancer Prevention 2013 14 3093 3099 10.7314/APJCP.2013.14.5. 3093
47. Gao Y., Wang H. Y., Inositol pentakisphosphate mediates Wnt/ β -catenin signaling. Journal of Biological Chemistry 2007 282 36 26490 26502 2-s2.0-34548859800 10.1074/jbc.M702106200 (Pubitemid 47443818)
48. Araki Y., Okamura S., Hussain S. P., Nagashima M., He P., Shiseki M., Miura K., Harris C. C., Regulation of cyclooxygenase-2 expression by the WNT and ras pathways. Cancer Research 2003 63 3 728 734 2-s2.0-0037310126 (Pubitemid 36158154)
49. Dimberg J., Hugander A., Sirsjö A., Söderkvist P., Enhanced expression of cyclooxygenase-2 and nuclear β -catenin are related to mutations in the APC gene in human colorectal cancer. Anticancer Research 2001 21 2 A 911 916 2-s2.0-0035000492 (Pubitemid 32494189)
50. Kim S. J., Im D. S., Kim S. H., Ryu J. H., Hwang S. G., Seong J. K., Chun C. H., Chun J. S., β -Catenin regulates expression of cyclooxygenase-2 in articular chondrocytes. Biochemical and Biophysical Research Communications 2002 296 1 221 226 2-s2.0-0036041108 10.1016/S0006-291X(02)00824-0 (Pubitemid 35002082)