Binding of complement inhibitor C4b-binding protein to a highly virulent streptococcus pyogenes M1 strain is mediated by protein H and enhances adhesion to and invasion of endothelial cells

Journal of Biological Chemistry

Volumn 288, Issue 45, 2013, Pages 32172-32183

  Ermert, David ^a   Weckel, Antonin ^a   Agarwal, Vaibhav ^a   Frick, Inga Maria ^a   Björck, Lars ^a   Blom, Anna M ^a  

^a LUND UNIVERSITY   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL SURFACES; BINDING PROTEINS; COFACTOR ACTIVITY; IMMOBILIZED PROTEINS; N-TERMINAL DOMAINS; POSITIVELY CHARGED; STREPTOCOCCUS PYOGENES; STRONG CORRELATION;

ADHESION; AMINO ACIDS; PEPTIDES;

ENDOTHELIAL CELLS;

BACTERIAL PROTEIN; COMPLEMENT COMPONENT C3B; COMPLEMENT COMPONENT C4; COMPLEMENT COMPONENT C4B; COMPLEMENT COMPONENT C4B BINDING PROTEIN; COMPLEMENT COMPONENT C4C; COMPLEMENT COMPONENT C4D; COMPLEMENT CONTROL PROTEIN 1; COMPLEMENT CONTROL PROTEIN 2; IODINE 125; PROTEIN H; RECOMBINANT PROTEIN; REGULATOR PROTEIN; UNCLASSIFIED DRUG;

AMINO ACID COMPOSITION; AMINO TERMINAL SEQUENCE; ARTICLE; BACTERIAL STRAIN; BACTERIAL VIRULENCE; BACTERIUM ADHERENCE; CELL INVASION; COMPLEMENT DEPOSITION; CONTROLLED STUDY; CORRELATION ANALYSIS; ENDOTHELIUM CELL; GENE MUTATION; HUMAN; HUMAN CELL; INHIBITION KINETICS; MICROARRAY ANALYSIS; NONHUMAN; OPSONIZATION; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DEGRADATION; PROTEIN DOMAIN; PROTEIN INTERACTION; PROTEIN PROCESSING; STREPTOCOCCUS PYOGENES; SURFACE PLASMON RESONANCE;

COMPLEMENT; HOST-PATHOGEN INTERACTIONS; PEPTIDE ARRAYS; PROTEIN-PROTEIN INTERACTIONS; STREPTOCOCCUS PYOGENES; VIRULENCE FACTORS;

BACTERIAL ADHESION; BINDING SITES; CELLS, CULTURED; COMPLEMENT C4B; COMPLEMENT C4B-BINDING PROTEIN; FEMALE; HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS; HUMANS; MALE; MUTATION; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; RECOMBINANT PROTEINS; STREPTOCOCCUS PYOGENES; SURFACE PLASMON RESONANCE; VIRULENCE FACTORS;

EID: 84887432633     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M113.502955     Document Type: Article

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