Fosphenytoin for seizure prevention in childhood coma in Africa: A randomized clinical trial

Journal of Critical Care

Volumn 28, Issue 6, 2013, Pages 1086-1092

  Gwer, Samson A ^a,b   Idro, Richard I ^c,d   Fegan, Gregory ^d,e   Chengo, Eddie M ^d   Mpoya, Ayub ^d   Kivaya, Esther ^d   Crawley, Jane ^f   Muchohi, Simon N ^d   Kihara, Michael N ^d,g   Ogutu, Bernhards R ^h,i   Kirkham, Fenella J ^j,k   Newton, Charles R ^d,f,k,l  

^a KENYATTA UNIVERSITY   (Kenya)

^b AFYA RESEARCH AFRICA   (Kenya)

^c MAKERERE UNIVERSITY COLLEGE OF HEALTH SCIENCES   (Uganda)

^d KENYA MEDICAL RESEARCH INSTITUTE   (Kenya)

^e LONDON SCHOOL OF HYGIENE AND TROPICAL MEDICINE   (United Kingdom)

^f UNIVERSITY OF OXFORD   (United Kingdom)

^g ALLIANT INTERNATIONAL UNIVERSITY   (United States)

^h Kondele Children's Hospital   (Kenya)

ⁱ KENYA MEDICAL RESEARCH INSTITUTE   (Kenya)

^j UNIVERSITY HOSPITAL SOUTHAMPTON NHS FOUNDATION TRUST   (United Kingdom)

^k UNIVERSITY COLLEGE LONDON   (United Kingdom)

^l UNIVERSITY OF OXFORD   (United Kingdom)

more..

Author keywords

Anticonvulsants; Child; Coma; Prophylaxis; Seizure

Indexed keywords

ANTIINFECTIVE AGENT; ANTIMALARIAL AGENT; DIAZEPAM; FOSPHENYTOIN SODIUM; MIDAZOLAM; PARALDEHYDE; PHENOBARBITAL; PHENYTOIN; PLACEBO; THIOPENTAL; VALPROIC ACID;

ACUTE DISEASE; ADOLESCENT; AFRICA; ARTICLE; BACTERIAL MENINGITIS; BRAIN DISEASE; BRAIN MALARIA; CHILD; CHILD DEATH; CHILDHOOD COMA; CHILDHOOD DISEASE; COGNITIVE DEFECT; COMA; CONTROLLED STUDY; DOUBLE BLIND PROCEDURE; DRUG BLOOD LEVEL; FEMALE; HOSPITAL DISCHARGE; HUMAN; HYPOTENSION; INJECTION SITE INDURATION; INJECTION SITE REACTION; INJECTION SITE SWELLING; KENYA; MAJOR CLINICAL STUDY; MALARIA; MALE; MORBIDITY; NEUROLOGIC DISEASE; PEDIATRIC HOSPITAL; PREVALENCE; RANDOMIZED CONTROLLED TRIAL; RESPIRATION DEPRESSION; SEIZURE; SINGLE DRUG DOSE;

ANTICONVULSANTS; CHILD; COMA; PROPHYLAXIS; SEIZURE;

ADOLESCENT; ANTICONVULSANTS; CHILD; CHILD, PRESCHOOL; COMA; DOUBLE-BLIND METHOD; ELECTROENCEPHALOGRAPHY; FEMALE; HUMANS; INFANT; INJECTIONS, INTRAMUSCULAR; KENYA; MALE; PHENYTOIN; PLACEBOS; SEIZURES; TREATMENT OUTCOME;

EID: 84887412105     PISSN: 08839441     EISSN: 15578615     Source Type: Journal    
DOI: 10.1016/j.jcrc.2013.09.001     Document Type: Article

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