Conformational change of a unique sequence in a fungal galectin from Agrocybe cylindracea controls glycan ligand-binding specificity

FEBS Letters

Volumn 587, Issue 22, 2013, Pages 3620-3625

  Kuwabara, Naoyuki ^a   Hu, Dan ^b   Tateno, Hiroaki ^b   Makyio, Hisayoshi ^a   Hirabayashi, Jun ^b   Kato, Ryuichi ^a  

^a INSTITUTE OF MATERIALS STRUCTURE SCIENCE   (Japan)

^b NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY AIST   (Japan)

Author keywords

ACG; Galectin; Glycan; Protein engineering; Saccharide; X ray crystallography

Indexed keywords

ALANINE; ASPARAGINE; CARBOHYDRATE; GALECTIN; GLYCAN; LACTOSE; PROLINE; THREONINE;

AGROCYBE CYLINDRACEA; AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ARTICLE; BINDING SITE; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; CRYSTAL STRUCTURE; GENE INSERTION SEQUENCE; LIGAND BINDING; MOLECULAR RECOGNITION; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; SEQUENCE ALIGNMENT; WILD TYPE; X RAY CRYSTALLOGRAPHY;

A-TETRA; ACG; AGROCYBE CYLINDRACEA GALECTIN; CARBOHYDRATE RECOGNITION DOMAIN; CRD; GALECTIN; GALNACΑ1-3(FUCΑ1-2)GALΒ1-4GLCNAC; GLYCAN; PEG; POLYETHYLENE GLYCOL; PROTEIN ENGINEERING; RMSD; ROOT-MEAN-SQUARE DEVIATION; SACCHARIDE; X-RAY CRYSTALLOGRAPHY;

AGROCYBE; AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; CRYSTALLOGRAPHY, X-RAY; FUNGAL PROTEINS; GALECTINS; HYDROGEN BONDING; LACTOSE; LIGANDS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; PROTEIN BINDING; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY;

AGROCYBE CYLINDRACEA;

EID: 84887402119     PISSN: 00145793     EISSN: 18733468     Source Type: Journal    
DOI: 10.1016/j.febslet.2013.08.046     Document Type: Article

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