-
1
-
-
84872091789
-
Heart disease and stroke statistics-2013 update a report from the american heart association
-
Go AS, Mozaffarian D, Roger VL et al. Heart disease and stroke statistics-2013 update a report from the American Heart Association. Circulation 127(1), e6-e245 (2012
-
(2012)
Circulation
, vol.127
, Issue.1
-
-
Go, A.S.1
Mozaffarian, D.2
Roger, V.L.3
-
2
-
-
84875720372
-
Use of clopidogrel with or without aspirin in patients taking oral anticoagulant therapy and undergoing percutaneous coronary intervention: An open-label, randomised, controlled trial
-
Dewilde WJ, Oirbans T, Verheugt FW et al. Use of clopidogrel with or without aspirin in patients taking oral anticoagulant therapy and undergoing percutaneous coronary intervention: An open-label, randomised, controlled trial. Lancet 381(9872), 1107-1115 (2013
-
(2013)
Lancet
, vol.381
, Issue.9872
, pp. 1107-1115
-
-
Dewilde, W.J.1
Oirbans, T.2
Verheugt, F.W.3
-
3
-
-
0035899289
-
Effects of clopidogrel in addition to aspirin in patients with acute coronary syndromes without ST-segment elevation
-
Yusuf S, Zhao F, Mehta SR, Chrolavicius S, Tognoni G, Fox KK. Effects of clopidogrel in addition to aspirin in patients with acute coronary syndromes without ST-segment elevation. N. Engl. J. Med. 345(7), 494-502 (2001
-
(2001)
N. Engl. J. Med
, vol.345
, Issue.7
, pp. 494-502
-
-
Yusuf, S.1
Zhao, F.2
Mehta, S.R.3
Chrolavicius, S.4
Tognoni, G.5
Fox, K.K.6
-
4
-
-
58749094444
-
Cytochrome p-450 polymorphisms and response to clopidogrel
-
Mega JL, Close SL, Wiviott SD et al. Cytochrome p-450 polymorphisms and response to clopidogrel. N. Engl. J. Med. 360(4), 354-362 (2009
-
(2009)
N. Engl. J. Med
, vol.360
, Issue.4
, pp. 354-362
-
-
Mega, J.L.1
Close, S.L.2
Wiviott, S.D.3
-
5
-
-
36148983750
-
Prasugrel versus clopidogrel in patients with acute coronary syndromes
-
Wiviott SD, Braunwald E, McCabe CH et al. Prasugrel versus clopidogrel in patients with acute coronary syndromes. N. Engl. J. Med. 357(20), 2001-2015 (2007
-
(2007)
N. Engl. J. Med
, vol.357
, Issue.20
, pp. 2001-2015
-
-
Wiviott, S.D.1
Braunwald, E.2
McCabe, C.H.3
-
6
-
-
70149101223
-
Ticagrelor versus clopidogrel in patients with acute coronary syndromes
-
Wallentin L, Becker RC, Budaj A et al. Ticagrelor versus clopidogrel in patients with acute coronary syndromes. N. Engl. J. Med. 361(11), 1045-1057 (2009
-
(2009)
N. Engl. J. Med
, vol.361
, Issue.11
, pp. 1045-1057
-
-
Wallentin, L.1
Becker, R.C.2
Budaj, A.3
-
7
-
-
84866368808
-
2012 accf/aha focused update of the guideline for the management of patients with unstable angina/non-st-elevation myocardial infarction (updating the 2007 guideline and replacing the2011 focused update): A report of the american college of cardiology foundation/american heart association task force on practice guidelines
-
Jneid H, Anderson JL, Wright RS et al. 2012 ACCF/AHA focused update of the guideline for the management of patients with unstable angina/non-ST- elevation myocardial infarction (updating the 2007 guideline and replacing the2011 focused update): A report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines. J. Am. Coll. Cardiol. 60(7), 645-681 (2012
-
(2012)
J. Am. Coll. Cardiol
, vol.60
, Issue.7
, pp. 645-681
-
-
Jneid, H.1
Anderson, J.L.2
Wright, R.S.3
-
8
-
-
84866732231
-
ESC Guidelines for the management of acute myocardial infarction in patients presenting with ST-segment elevation
-
Steg PG, James SK, Atar D et al. ESC Guidelines for the management of acute myocardial infarction in patients presenting with ST-segment elevation. Eur. Heart J. 33(20), 2569-2619 (2012
-
(2012)
Eur. Heart J.
, vol.33
, Issue.20
, pp. 2569-2619
-
-
Steg, P.G.1
James, S.K.2
Atar, D.3
-
9
-
-
84856794168
-
Primary and secondary prevention of cardiovascular disease: Antithrombotic therapy and prevention of thrombosis
-
9th ed: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines Suppl
-
Vandvik PO, Lincoff AM, Gore JM et al. Primary and secondary prevention of cardiovascular disease: Antithrombotic Therapy and Prevention of Thrombosis, 9th ed: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines. Chest 141(2 Suppl.), e637S-668S (2012
-
(2012)
Chest
, vol.141
, Issue.2
-
-
Vandvik, P.O.1
Lincoff, A.M.2
Gore, J.M.3
-
10
-
-
79960836902
-
Platelet aggregation pathway
-
Sangkuhl K, Shuldiner AR, Klein TE, Altman RB. Platelet aggregation pathway. Pharmacogenet. Genomics 21(8), 516-521 (2011
-
(2011)
Pharmacogenet. Genomics
, vol.21
, Issue.8
, pp. 516-521
-
-
Sangkuhl, K.1
Shuldiner, A.R.2
Klein, T.E.3
Altman, R.B.4
-
11
-
-
70449484408
-
Ticagrelor: The first reversibly binding oral P2Y12 receptor antagonist
-
Husted S, van Giezen JJ. Ticagrelor: The first reversibly binding oral P2Y12 receptor antagonist. Cardiovasc. Ther. 27(4), 259-274 (2009
-
(2009)
Cardiovasc. Ther
, vol.27
, Issue.4
, pp. 259-274
-
-
Husted, S.1
Van Giezen, J.J.2
-
12
-
-
18044388905
-
Preclinical and clinical studies with selective reversible direct P2Y12 antagonists
-
van Giezen JJ, Humphries RG. Preclinical and clinical studies with selective reversible direct P2Y12 antagonists. Semin. Thromb. Hemost. 31(2), 195-204 (2005
-
(2005)
Semin. Thromb. Hemost
, vol.31
, Issue.2
, pp. 195-204
-
-
Van Giezen, J.J.1
Humphries, R.G.2
-
13
-
-
23044461331
-
Single-dose pharmacokinetics and pharmacodynamics of azd6140-An ora reversible adp receptor antagonist
-
Peters G RG. Single-dose pharmacokinetics and pharmacodynamics of AZD6140-An ora reversible ADP receptor antagonist. Haematoligica 989, 14-15 (2004
-
(2004)
Haematoligica
, vol.989
, pp. 14-15
-
-
Peters, G.R.G.1
-
14
-
-
70349865565
-
Multiple-dose pharmacokinetics (pk) and pharmacodynamics (pd) of the oral reversible, orally active adp receptor antagonist azd6140
-
Peters GR BK, Winter HR. Multiple-dose pharmacokinetics (PK) and pharmacodynamics (PD) of the oral reversible, orally active ADP receptor antagonist AZD6140. Eur. Heart J. 27(P4556) (2006
-
(2006)
Eur. Heart J.
, vol.27
-
-
Peters, G.R.B.K.1
Winter, H.R.2
-
15
-
-
77955832864
-
AZD6140, the first reversible oral platelet P2Y12 receptor antagonist, exhibits linear pharmacokinetics following multiple doses in healthy subjects, with greater and less variable inhibition of platelet aggregation compared with clopidogrel
-
Abstract 562
-
Butler K TR. AZD6140, the first reversible oral platelet P2Y12 receptor antagonist, exhibits linear pharmacokinetics following multiple doses in healthy subjects, with greater and less variable inhibition of platelet aggregation compared with clopidogrel. Eur. Heart J. 15, e684-e685, Abstract 562 (2008
-
(2008)
Eur. Heart J.
, vol.15
-
-
Butler, K.T.R.1
-
16
-
-
33646261670
-
Pharmacodynamics, pharmacokinetics, and safety of the oral reversible P2Y12 antagonist AZD6140 with aspirin in patients with atherosclerosis: A double-blind comparison to clopidogrel with aspirin
-
Husted S, Emanuelsson H, Heptinstall S, Sandset PM, Wickens M, Peters G. Pharmacodynamics, pharmacokinetics, and safety of the oral reversible P2Y12 antagonist AZD6140 with aspirin in patients with atherosclerosis: A double-blind comparison to clopidogrel with aspirin. Eur. Heart J. 27(9), 1038-1047 (2006
-
(2006)
Eur. Heart J.
, vol.27
, Issue.9
, pp. 1038-1047
-
-
Husted, S.1
Emanuelsson, H.2
Heptinstall, S.3
Sandset, P.M.4
Wickens, M.5
Peters, G.6
-
17
-
-
35548995394
-
Safety, tolerability, and initial efficacy of azd6140, the first reversible oral adenosine diphosphate receptor antagonist, compared with clopidogrel, in patients with non-st-segment elevation acute coronary syndrome: Primary results of the disperse-2 trial
-
Cannon CP, Husted S, Harrington RA et al. Safety, tolerability, and initial efficacy of AZD6140, the first reversible oral adenosine diphosphate receptor antagonist, compared with clopidogrel, in patients with non-ST-segment elevation acute coronary syndrome: Primary results of the DISPERSE-2 trial. J. Am. Coll. Cardiol. 50(19), 1844-1851 (2007
-
(2007)
J. Am. Coll. Cardiol
, vol.50
, Issue.19
, pp. 1844-1851
-
-
Cannon, C.P.1
Husted, S.2
Harrington, R.A.3
-
18
-
-
35548933800
-
Inhibition of platelet aggregation by azd6140, a reversible oral p2y12 receptor antagonist, compared with clopidogrel in patients with acute coronary syndromes
-
Storey RF, Husted S, Harrington RA et al. Inhibition of platelet aggregation by AZD6140, a reversible oral P2Y12 receptor antagonist, compared with clopidogrel in patients with acute coronary syndromes. J. Am. Coll. Cardiol. 50(19), 1852-1856 (2007
-
(2007)
J. Am. Coll. Cardiol
, vol.50
, Issue.19
, pp. 1852-1856
-
-
Storey, R.F.1
Husted, S.2
Harrington, R.A.3
-
19
-
-
73949112820
-
Randomized double-blind assessment of the onset and offset of the antiplatelet effects of ticagrelor versus clopidogrel in patients with stable coronary artery disease: The onset/offset study
-
Gurbel PA, Bliden KP, Butler K et al. Randomized double-blind assessment of the ONSET and OFFSET of the antiplatelet effects of ticagrelor versus clopidogrel in patients with stable coronary artery disease: The ONSET/OFFSET study. Circulation 120(25), 2577-2585 (2009
-
(2009)
Circulation
, vol.120
, Issue.25
, pp. 2577-2585
-
-
Gurbel, P.A.1
Bliden, K.P.2
Butler, K.3
-
20
-
-
77950508416
-
Response to ticagrelor in clopidogrel nonresponders and responders and effect of switching therapies: The respond study
-
Gurbel PA, Bliden KP, Butler K et al. Response to ticagrelor in clopidogrel nonresponders and responders and effect of switching therapies: The RESPOND study. Circulation 121(10), 1188-1199 (2010
-
(2010)
Circulation
, vol.121
, Issue.10
, pp. 1188-1199
-
-
Gurbel, P.A.1
Bliden, K.P.2
Butler, K.3
-
21
-
-
84860463430
-
Pharmacokinetics and pharmacodynamics of ticagrelor in patients with stable coronary artery disease: Results from the onset-offset and respond studies
-
Husted SE, Storey RF, Bliden K et al. Pharmacokinetics and pharmacodynamics of ticagrelor in patients with stable coronary artery disease: Results from the ONSET-OFFSET and RESPOND studies. Clin. Pharmacokinet. 51(6), 397-409 (2012
-
(2012)
Clin. Pharmacokinet
, vol.51
, Issue.6
, pp. 397-409
-
-
Husted, S.E.1
Storey, R.F.2
Bliden, K.3
-
22
-
-
84863989810
-
Ticagrelor in clopidogrel-resistant patients undergoing maintenance hemodialysis
-
Alexopoulos D, Xanthopoulou I, Plakomyti TE, Goudas P, Koutroulia E, Goumenos D. Ticagrelor in clopidogrel-resistant patients undergoing maintenance hemodialysis. Am. J. Kidney Dis. 60(2), 332-333 (2012
-
(2012)
Am. J. Kidney Dis
, vol.60
, Issue.2
, pp. 332-333
-
-
Alexopoulos, D.1
Xanthopoulou, I.2
Plakomyti, T.E.3
Goudas, P.4
Koutroulia, E.5
Goumenos, D.6
-
23
-
-
82955187874
-
Bleeding complications with the p2y12 receptor antagonists clopidogrel and ticagrelor in the platelet inhibition and patient outcomes (plato) trial
-
Becker RC, Bassand JP, Budaj A et al. Bleeding complications with the P2Y12 receptor antagonists clopidogrel and ticagrelor in the PLATelet inhibition and patient Outcomes (PLATO) trial. Eur. Heart J. 32(23), 2933-2944 (2011
-
(2011)
Eur. Heart J.
, vol.32
, Issue.23
, pp. 2933-2944
-
-
Becker, R.C.1
Bassand, J.P.2
Budaj, A.3
-
24
-
-
80052904190
-
Implications of variability in definition and reporting of major bleeding in randomized trials of oral P2Y12 inhibitors for acute coronary syndromes
-
Quinlan DJ, Eikelboom JW, Goodman SG et al. Implications of variability in definition and reporting of major bleeding in randomized trials of oral P2Y12 inhibitors for acute coronary syndromes. Eur. Heart J. 32(18), 2256-2265 (2011
-
(2011)
Eur. Heart J.
, vol.32
, Issue.18
, pp. 2256-2265
-
-
Quinlan, D.J.1
Eikelboom, J.W.2
Goodman, S.G.3
-
25
-
-
84873987243
-
Reduction in first and recurrent cardiovascular events with ticagrelor compared with clopidogrel in the plato study
-
Kohli P, Wallentin L, Reyes E et al. Reduction in first and recurrent cardiovascular events with ticagrelor compared with clopidogrel in the PLATO study. Circulation 127(6), 673-680 (2013
-
(2013)
Circulation
, vol.127
, Issue.6
, pp. 673-680
-
-
Kohli, P.1
Wallentin, L.2
Reyes, E.3
-
26
-
-
74649085430
-
Comparison of ticagrelor with clopidogrel in patients with a planned invasive strategy for acute coronary syndromes (plato): A randomised double-blind study
-
Cannon CP, Harrington RA, James S et al. Comparison of ticagrelor with clopidogrel in patients with a planned invasive strategy for acute coronary syndromes (PLATO): A randomised double-blind study. Lancet 375(9711), 283-293 (2010
-
(2010)
Lancet
, vol.375
, Issue.9711
, pp. 283-293
-
-
Cannon, C.P.1
Harrington, R.A.2
James, S.3
-
27
-
-
82255188048
-
Ticagrelor versus clopidogrel in patients with acute coronary syndromes intended for non-invasive management: Substudy from prospective randomised platelet inhibition and patient outcomes (plato) trial
-
James SK, Roe MT, Cannon CP et al. Ticagrelor versus clopidogrel in patients with acute coronary syndromes intended for non-invasive management: Substudy from prospective randomised PLATelet inhibition and patient Outcomes (PLATO) trial. BMJ 342, d3527 (2011
-
(2011)
BMJ
, vol.342
-
-
James, S.K.1
Roe, M.T.2
Cannon, C.P.3
-
28
-
-
78650174722
-
Ticagrelor versus clopidogrel in patients with st-elevation acute coronary syndromes intended for reperfusion with primary percutaneous coronary intervention: A platelet inhibition and patient outcomes (plato) trial subgroup analysis
-
Steg PG, James S, Harrington RA et al. Ticagrelor versus clopidogrel in patients with ST-elevation acute coronary syndromes intended for reperfusion with primary percutaneous coronary intervention: A Platelet Inhibition and Patient Outcomes (PLATO) trial subgroup analysis. Circulation 122(21), 2131-2141 (2010
-
(2010)
Circulation
, vol.122
, Issue.21
, pp. 2131-2141
-
-
Steg, P.G.1
James, S.2
Harrington, R.A.3
-
29
-
-
79551563636
-
Ticagrelor versus clopidogrel in patients with acute coronary syndromes undergoing coronary artery bypass surgery: Results from the plato (platelet inhibition and patient outcomes) trial
-
Held C, Asenblad N, Bassand JP et al. Ticagrelor versus clopidogrel in patients with acute coronary syndromes undergoing coronary artery bypass surgery: Results from the PLATO (Platelet Inhibition and Patient Outcomes) trial. J. Am. Coll. Cardiol. 57(6), 672-684 (2011
-
(2011)
J. Am. Coll. Cardiol
, vol.57
, Issue.6
, pp. 672-684
-
-
Held, C.1
Asenblad, N.2
Bassand, J.P.3
-
30
-
-
84867582405
-
Factors contributing to the lower mortality with ticagrelor compared with clopidogrel in patients undergoing coronary artery bypass surgery
-
Varenhorst C, Alstrom U, Scirica BM et al. Factors contributing to the lower mortality with ticagrelor compared with clopidogrel in patients undergoing coronary artery bypass surgery. J. Am. Coll. Cardiol. 60(17), 1623-1630 (2012
-
(2012)
J. Am. Coll. Cardiol
, vol.60
, Issue.17
, pp. 1623-1630
-
-
Varenhorst, C.1
Alstrom, U.2
Scirica, B.M.3
-
31
-
-
84862146372
-
Ticagrelor versus clopidogrel in patients with acute coronary syndromes and a history of stroke or transient ischemic attack
-
James SK, Storey RF, Khurmi NS et al. Ticagrelor versus clopidogrel in patients with acute coronary syndromes and a history of stroke or transient ischemic attack. Circulation 125(23), 2914-2921 (2012
-
(2012)
Circulation
, vol.125
, Issue.23
, pp. 2914-2921
-
-
James, S.K.1
Storey, R.F.2
Khurmi, N.S.3
-
32
-
-
84887325372
-
Cardiovascular events in acute coronary syndrome patients with peripheral arterial disease treated with ticagrelor compared to clopidogrel: Data from the plato trial
-
Patel MR, Becker RC, Wojdyla DM et al. cardiovascular events in acute coronary syndrome patients with peripheral arterial disease treated with ticagrelor compared to clopidogrel: Data from the PLATO trial. Circulation 124, A14299 (2011
-
(2011)
Circulation
, vol.124
-
-
Patel, M.R.1
Becker, R.C.2
Wojdyla, D.M.3
-
33
-
-
77957270303
-
Ticagrelor versus clopidogrel in acute coronary syndromes in relation to renal function: Results from the platelet inhibition and patient outcomes (plato) trial
-
James S, Budaj A, Aylward P et al. Ticagrelor versus clopidogrel in acute coronary syndromes in relation to renal function: Results from the Platelet Inhibition and Patient Outcomes (PLATO) trial. Circulation 122(11), 1056-1067 (2010
-
(2010)
Circulation
, vol.122
, Issue.11
, pp. 1056-1067
-
-
James, S.1
Budaj, A.2
Aylward, P.3
-
34
-
-
78650368771
-
Ticagrelor vs clopidogrel in patients with acute coronary syndromes and diabetes: A substudy from the platelet inhibition and patient outcomes (plato) trial
-
James S, Angiolillo DJ, Cornel JH et al. Ticagrelor vs. clopidogrel in patients with acute coronary syndromes and diabetes: A substudy from the PLATelet inhibition and patient Outcomes (PLATO) trial. Eur. Heart J. 31(24), 3006-3016 (2010
-
(2010)
Eur. Heart J.
, vol.31
, Issue.24
, pp. 3006-3016
-
-
James, S.1
Angiolillo, D.J.2
Cornel, J.H.3
-
35
-
-
84868648318
-
Ticagrelor versus clopidogrel in elderly patients with acute coronary syndromes: A substudy from the prospective randomized platelet inhibition and patient outcomes (plato) trial
-
Husted S, James S, Becker RC et al. Ticagrelor versus clopidogrel in elderly patients with acute coronary syndromes: A substudy from the prospective randomized PLATelet inhibition and patient Outcomes (PLATO) trial. Circ. Cardiovasc. Qual. Outcomes 5(5), 680-688 (2012
-
(2012)
Circ. Cardiovasc. Qual. Outcomes
, vol.5
, Issue.5
, pp. 680-688
-
-
Husted, S.1
James, S.2
Becker, R.C.3
-
36
-
-
84866325657
-
Prior smoking status, clinical outcomes, and the comparison of ticagrelor with clopidogrel in acute coronary syndromes-insights from the platelet inhibition and patient outcomes (plato) trial
-
e331
-
Cornel JH, Becker RC, Goodman SG et al. Prior smoking status, clinical outcomes, and the comparison of ticagrelor with clopidogrel in acute coronary syndromes-insights from the PLATelet inhibition and patient Outcomes (PLATO) trial. Am. Heart J. 164(3), 334-342 e331 (2012
-
(2012)
Am. Heart J.
, vol.164
, Issue.3
, pp. 334-342
-
-
Cornel, J.H.1
Becker, R.C.2
Goodman, S.G.3
-
37
-
-
77958003916
-
Inhibitory effects of ticagrelor compared with clopidogrel on platelet function in patients with acute coronary syndromes: The plato (platelet inhibition and patient outcomes) platelet substudy
-
Storey RF, Angiolillo DJ, Patil SB et al. Inhibitory effects of ticagrelor compared with clopidogrel on platelet function in patients with acute coronary syndromes: The PLATO (PLATelet inhibition and patient Outcomes) PLATELET substudy. J. Am. Coll. Cardiol. 56(18), 1456-1462 (2010
-
(2010)
J. Am. Coll. Cardiol
, vol.56
, Issue.18
, pp. 1456-1462
-
-
Storey, R.F.1
Angiolillo, D.J.2
Patil, S.B.3
-
38
-
-
82955201646
-
Characterization of dyspnoea in plato study patients treated with ticagrelor or clopidogrel and its association with clinical outcomes
-
Storey RF, Becker RC, Harrington RA et al. Characterization of dyspnoea in PLATO study patients treated with ticagrelor or clopidogrel and its association with clinical outcomes. Eur. Heart J. 32(23), 2945-2953 (2011
-
(2011)
Eur. Heart J.
, vol.32
, Issue.23
, pp. 2945-2953
-
-
Storey, R.F.1
Becker, R.C.2
Harrington, R.A.3
-
39
-
-
84873712137
-
Ticagrelor enhances adenosine-induced coronary vasodilatory responses in humans
-
Wittfeldt A, Emanuelsson H, Brandrup-Wognsen G et al. Ticagrelor enhances adenosine-induced coronary vasodilatory responses in humans. J. Am. Coll. Cardiol. 61(7), 723-727 (2013
-
(2013)
J. Am. Coll. Cardiol
, vol.61
, Issue.7
, pp. 723-727
-
-
Wittfeldt, A.1
Emanuelsson, H.2
Brandrup-Wognsen, G.3
-
40
-
-
79955590021
-
The incidence of bradyarrhythmias and clinical bradyarrhythmic events in patients with acute coronary syndromes treated with ticagrelor or clopidogrel in the plato (platelet inhibition and patient outcomes) trial: Results of the continuous electrocardiographic assessment substudy
-
Scirica BM, Cannon CP, Emanuelsson H et al. The incidence of bradyarrhythmias and clinical bradyarrhythmic events in patients with acute coronary syndromes treated with ticagrelor or clopidogrel in the PLATO (Platelet Inhibition and Patient Outcomes) trial: Results of the continuous electrocardiographic assessment substudy. J. Am. Coll. Cardiol. 57(19), 1908-1916 (2011
-
(2011)
J. Am. Coll. Cardiol
, vol.57
, Issue.19
, pp. 1908-1916
-
-
Scirica, B.M.1
Cannon, C.P.2
Emanuelsson, H.3
-
41
-
-
84866479608
-
Ticagrelor inhibits adenosine uptake in vitro and enhances adenosine-mediated hyperemia responses in a canine model
-
van Giezen JJ, Sidaway J, Glaves P, Kirk I, Bjorkman JA. Ticagrelor inhibits adenosine uptake in vitro and enhances adenosine-mediated hyperemia responses in a canine model. J. Cardiovasc. Pharmacol. Ther. 17(2), 164-172 (2012
-
(2012)
J. Cardiovasc. Pharmacol. Ther
, vol.17
, Issue.2
, pp. 164-172
-
-
Van Giezen, J.J.1
Sidaway, J.2
Glaves, P.3
Kirk, I.4
Bjorkman, J.A.5
-
42
-
-
84887356178
-
Reduction in pulmonary adverse events and associated sepsis and mortality in acute coronary syndrome patients treated with ticagrelor compared to clopidogrel: A post hoc analysis of the plato study
-
Storey RF, Steg PG, James SK, Husted S, Cannon CP, Becker R, Ycas J, Asenblad N, Kilhamn J, Wallentin L. Reduction in pulmonary adverse events and associated sepsis and mortality in acute coronary syndrome patients treated with ticagrelor compared to clopidogrel: A post hoc analysis of the PLATO Study. J. Am. Coll. Cardiol. 59(13), E482 (2012
-
(2012)
J. Am. Coll. Cardiol
, vol.59
, Issue.13
-
-
Storey, R.F.1
Steg, P.G.2
James, S.K.3
Husted, S.4
Cannon, C.P.5
Becker, R.6
Ycas, J.7
Asenblad, N.8
Kilhamn, J.9
Wallentin, L.10
-
43
-
-
84873530056
-
Randomized assessment of ticagrelor versus prasugrel antiplatelet effects in patients with ST-segment-elevation myocardial infarction
-
Alexopoulos D, Xanthopoulou I, Gkizas V et al. Randomized assessment of ticagrelor versus prasugrel antiplatelet effects in patients with ST-segment-elevation myocardial infarction. Circ. Cardiovasc. Interv. 5(6), 797-804 (2012
-
(2012)
Circ. Cardiovasc. Interv
, vol.5
, Issue.6
, pp. 797-804
-
-
Alexopoulos, D.1
Xanthopoulou, I.2
Gkizas, V.3
-
44
-
-
84875997213
-
Comparison of prasugrel and ticagrelor loading doses in st-segment elevation myocardial infarction patients: Rapid (rapid activity of platelet inhibitor drugs) primary pci study
-
Parodi G, Valenti R, Bellandi B et al. Comparison of prasugrel and ticagrelor loading doses in ST-segment elevation myocardial infarction patients: RAPID (Rapid Activity of Platelet Inhibitor Drugs) primary PCI study. J. Am. Coll. Cardiol. 61(15), 1601-1606 (2013
-
(2013)
J. Am. Coll. Cardiol
, vol.61
, Issue.15
, pp. 1601-1606
-
-
Parodi, G.1
Valenti, R.2
Bellandi, B.3
-
45
-
-
84875779761
-
Effect of platelet inhibition with cangrelor during pci on ischemic events
-
Bhatt DL, Stone GW, Mahaffey KW et al. Effect of platelet inhibition with cangrelor during PCI on ischemic events. N. Engl J. Med. 368(14), 1303-1313 (2013
-
(2013)
N. Engl J. Med
, vol.368
, Issue.14
, pp. 1303-1313
-
-
Bhatt, D.L.1
Stone, G.W.2
Mahaffey, K.W.3
-
46
-
-
80051550924
-
Ticagrelor compared with clopidogrel by geographic region in the platelet inhibition and patient outcomes (plato) trial
-
Mahaffey KW, Wojdyla DM, Carroll K et al. Ticagrelor compared with clopidogrel by geographic region in the Platelet Inhibition and Patient Outcomes (PLATO) trial. Circulation 124(5), 544-554 (2011
-
(2011)
Circulation
, vol.124
, Issue.5
, pp. 544-554
-
-
Mahaffey, K.W.1
Wojdyla, D.M.2
Carroll, K.3
-
47
-
-
84871101391
-
Discharge aspirin dose and clinical outcomes in patients with acs: An analysis from the triton-Timi 38 study
-
Kohli P UJ, Murphy SA, Antman EA, Braunwald E, Wiviott SD. Discharge aspirin dose and clinical outcomes in patients with ACS: An analysis from the TRITON-TIMI 38 study. J. Am. Coll. Cardiol. 59(13s1), E342 (2012
-
(2012)
J. Am. Coll. Cardiol
, vol.59
, Issue.13 S1
-
-
Kohli P, U.J.1
Murphy, S.A.2
Antman, E.A.3
Braunwald, E.4
Wiviott, S.D.5
-
48
-
-
84872552570
-
Cost-effectiveness of treating acute coronary syndrome patients with ticagrelor for 12 months: Results from the plato study
-
Nikolic E, Janzon M, Hauch O, Wallentin L, Henriksson M. Cost-effectiveness of treating acute coronary syndrome patients with ticagrelor for 12 months: Results from the PLATO study. Eur. Heart J. 34(3), 220-228 (2013
-
(2013)
Eur. Heart J.
, vol.34
, Issue.3
, pp. 220-228
-
-
Nikolic, E.1
Janzon, M.2
Hauch, O.3
Wallentin, L.4
Henriksson, M.5
-
49
-
-
81855211733
-
Dosing clopidogrel based on cyp2c19 genotype and the effect on platelet reactivity in patients with stable cardiovascular disease
-
Mega JL, Hochholzer W, Frelinger AL, III et al. Dosing clopidogrel based on CYP2C19 genotype and the effect on platelet reactivity in patients with stable cardiovascular disease. JAMA 306(20), 2221-2228 (2011
-
(2011)
JAMA
, vol.306
, Issue.20
, pp. 2221-2228
-
-
Mega, J.L.1
Hochholzer, W.2
Frelinger III, A.L.3
-
50
-
-
84862907587
-
Rivaroxaban in patients with a recent acute coronary syndrome
-
Mega JL, Braunwald E, Wiviott SD et al. Rivaroxaban in patients with a recent acute coronary syndrome. N. Engl. J. Med. 366(1), 9-19 (2012
-
(2012)
N. Engl. J. Med
, vol.366
, Issue.1
, pp. 9-19
-
-
Mega, J.L.1
Braunwald, E.2
Wiviott, S.D.3
-
51
-
-
84859555815
-
Vorapaxar in the secondary prevention of atherothrombotic events
-
Morrow DA, Braunwald E, Bonaca MP et al. Vorapaxar in the secondary prevention of atherothrombotic events. N. Engl. J. Med. 366(15), 1404-1413 (2012
-
(2012)
N. Engl. J. Med
, vol.366
, Issue.15
, pp. 1404-1413
-
-
Morrow, D.A.1
Braunwald, E.2
Bonaca, M.P.3
-
52
-
-
83655177669
-
Thrombin-receptor antagonist vorapaxar in acute coronary syndromes
-
Tricoci P, Huang Z, Held C et al. Thrombin-receptor antagonist vorapaxar in acute coronary syndromes. N. Engl. J. Med. 366(1), 20-33 (2012
-
(2012)
N. Engl. J. Med
, vol.366
, Issue.1
, pp. 20-33
-
-
Tricoci, P.1
Huang, Z.2
Held, C.3
-
53
-
-
33747874088
-
A randomized comparison of high clopidogrel loading doses in patients with non-st-segment elevation acute coronary syndromes: The albion (assessment of the best loading dose of clopidogrel to blunt platelet activation, inflammation and ongoing necrosis) trial
-
Montalescot G, Sideris G, Meuleman C et al. A randomized comparison of high clopidogrel loading doses in patients with non-ST-segment elevation acute coronary syndromes: The ALBION (Assessment of the Best Loading Dose of Clopidogrel to Blunt Platelet Activation, Inflammation and Ongoing Necrosis) trial. J. Am. Coll. Cardiol. 48(5), 931-938 (2006
-
(2006)
J. Am. Coll. Cardiol
, vol.48
, Issue.5
, pp. 931-938
-
-
Montalescot, G.1
Sideris, G.2
Meuleman, C.3
-
54
-
-
33845451677
-
A comparison of prasugrel and clopidogrel loading doses on platelet function: Magnitude of platelet inhibition is related to active metabolite formation
-
e69-16
-
Brandt JT, Payne CD, Wiviott SD et al. A comparison of prasugrel and clopidogrel loading doses on platelet function: Magnitude of platelet inhibition is related to active metabolite formation. Am. Heart J. 153(1), 66 e69-16 (2007
-
(2007)
Am. Heart J.
, vol.153
, Issue.1
, pp. 66
-
-
Brandt, J.T.1
Payne, C.D.2
Wiviott, S.D.3
-
55
-
-
72749128296
-
Pharmacokinetics and pharmacodynamics of a bolus and infusion of cangrelor: A direct, parenteral P2Y12 receptor antagonist
-
Akers WS, Oh JJ, Oestreich JH, Ferraris S, Wethington M, Steinhubl SR. Pharmacokinetics and pharmacodynamics of a bolus and infusion of cangrelor: A direct, parenteral P2Y12 receptor antagonist. J. Clin. Pharmacol. 50(1), 27-35 (2010
-
(2010)
J. Clin. Pharmacol
, vol.50
, Issue.1
, pp. 27-35
-
-
Akers, W.S.1
Oh, J.J.2
Oestreich, J.H.3
Ferraris, S.4
Wethington, M.5
Steinhubl, S.R.6
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