Chronic antidepressant desipramine treatment increases open field-induced brain expression and spleen production of interleukin 10 in rats

Brain Research Bulletin

Volumn 99, Issue , 2013, Pages 117-131

  Wrona, Danuta ^a   Listowska, Magdalena ^a   Kubera, Marta ^b   Majkutewicz, Irena ^a   Glac, Wojciech ^a   Wojtyła Kuchta, Bogumiła ^a   Plucińska, Karolina ^a   Grembecka, Beata ^a   Podlacha, Magdalena ^a  

^a UNIVERSITY OF GDA SK   (Poland)

^b INSTITUTE OF PHARMACOLOGY   (Poland)

Author keywords

Desipramine; Interleukin 10; Natural killer cells; Open field; Response to novelty; Social position

Indexed keywords

ANTINEOPLASTIC AGENT; CORTICOSTERONE; DESIPRAMINE; GAMMA INTERFERON; INTERLEUKIN 10; PROTEIN FOS;

AMYGDALOID NUCLEUS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; ARTICLE; BRAIN; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; CORTICOSTERONE BLOOD LEVEL; CYTOKINE PRODUCTION; CYTOKINE RESPONSE; DENTATE GYRUS; ENZYME LINKED IMMUNOSORBENT ASSAY; HIPPOCAMPUS; IMMUNOHISTOCHEMISTRY; LOCOMOTION; MALE; NATURAL KILLER CELL; NONHUMAN; OPEN FIELD TEST; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SPLEEN; SPLEEN CELL; TREATMENT DURATION;

DESIPRAMINE; INTERLEUKIN 10; NATURAL KILLER CELLS; OPEN FIELD; RESPONSE TO NOVELTY; SOCIAL POSITION;

ANIMALS; ANTIDEPRESSIVE AGENTS, TRICYCLIC; BRAIN; CORTICOSTERONE; DESIPRAMINE; EXPLORATORY BEHAVIOR; INTERFERON-GAMMA; INTERLEUKIN-10; INTERPERSONAL RELATIONS; KILLER CELLS, NATURAL; LEUKOCYTES, MONONUCLEAR; MALE; PROTO-ONCOGENE PROTEINS C-FOS; RATS; RATS, WISTAR; SPLEEN; STATISTICS, NONPARAMETRIC; TIME FACTORS;

EID: 84887322754     PISSN: 03619230     EISSN: 18732747     Source Type: Journal    
DOI: 10.1016/j.brainresbull.2013.10.002     Document Type: Article

References (54)

1. Albonetti M.E., Farabollini F. Social stress by repeated defeat: effects on social behavior and emotionality. Behav. Brain Res. 1994, 62:187-193.
2. Azpiroz A., Fano E., Garmendia L., Arregi A., Cacho R., Beitia G., Brain P.F. Effects of chronic mild stress (CMS) and imipramine administration, on spleen mononuclear cell proliferative response, serum corticosterone level and brain norepinephrine content in male mice. Psychoneuroendocrinology 1999, 24:345-361.
3. Badowska-Szalewska E., Klejbor I., Cecot T., Spodnik J.H., Moryś J. Changes in NGF/c-Fos double staining in the structures of the limbic system in juvenile and aged rats exposed to forced swim test. Acta Neurobiol. Exp. 2009, 69:448-458.
4. Basso A.M., Depiante-Depaoli M., Molina V.A. Chronic variable stress facilitates tumoral growth reversal by imipramine administration. Life Sci. 1992, 50:1789-1796.
5. Blanchard D.C., Sakai R.R., McEwen B., Weiss S.M., Blanchard R.J. Subordination stress: behavioral, brain, and neuroendocrine correlates. Behav. Brain Res. 1993, 58:113-121.
6. Broderick P.A. Interleukin 1α alters hippocampal serotonin and norepinephrine release during open-field behavior in Sprague-Dawley animals: differences from the Fawn-Hooded animal model of depression. Prog. Neuro-Psychoph. 2002, 26:1355-1372.
7. Campeau S., Hayward M.D., Hope B.T., Rosen J.B., Nestler E.J., Davis M. Induction of the c-fos proto-oncogene in rat amygdala during unconditioned and conditioned fear. Brain Res. 1991, 565:349-352.
8. Chan R.K., Brown E.R., Ericsson A., Kovacs K.J., Sawchenko P.E. A comparison of two immediate-early genes, c-fos and NGF1-B, as markers for functional activation in stress-related neuroendocrine circuitry. J. Neurosci. 1993, 13:5126-5138.
9. Clamage D.M., Sanford C.S., Vander A.J., Mouw D.R. Effects of psychosocial stimuli on plasma renin in rats. Am. J. Physiol. 1976, 231:1290-1294.
10. Connor T.J., Kelly J.P., Leonard B.E. Forced swim test-induced endocrine and immune changes in the rat: effect of subacute desipramine treatment. Pharmacol. Biochem. Behav. 1998, 59:171-177.
11. Dhabhar F.S., McEwen B.S. Enhancing versus suppressive effects of stress hormones on skin immune function. Proc. Natl. Acad. Sci. U.S.A. 1999, 96:1059-1064.
12. Eisen J., Irwin J., Quay J., Livnat S. The effect of antidepressants on immune function in mice. Biol. Psychiatry 1989, 26:805-817.
13. Flandreau E.I., Ressler K.J., Owens M.J., Nemeroff C.B. Chronic overexpression of corticotrophin-releasing factor from the central amygdala produced HPA axis hyperactivity and behavioural anxiety associated with gene-expression changes in the hippocampus and paraventricular nucleus of the hypothalamus. Psychoneuroendocrinology 2012, 37:27-38.
14. Harris E.F., Fehl L.M., Shahkolahi A. Activity of murine killer cells during behavioural despair conditioning with and without imipramine treatment. J. Neuroimmunol. 1987, 16:71.
15. Holsen L.M., Lancaster K., Klibanski A., Whitfield-Gabrieli S., Cherkerzian S., Buka S., Goldstein J.M. HPA-axis hormone modulation of stress response circuitry activity in women with remitted major depression. Neuroscience 2013, 250:733-742.
16. Jama A., Cecchi M., Calvo N., Watson S.J., Akil H. Inter-individual differences in novelty-seeking behavior in rats predict differential responses to desipramine in the forced swim test. Psychopharmacology (Berl) 2008, 198:333-340.
17. Kabbaj M., Akil H. Individual differences in novelty-seeking behavior in rats: a c-fos study. Neuroscience 2001, 106:535-545.
18. Kenis G., Maes M. Effects of antidepressants on the production of cytokines. Int. J. Neuropsychopharmacol. 2002, 5:401-412.
19. Koldzic-Zivanovic N., Tu H., Juelich T.L., Rady P.L., Tyring S.K., Hudnall S.D., Smith E.M., Huges T.K. Regulation of adrenal glucocorticoid synthesis by interleukin-10: a preponderance of IL-10 receptor in the adrenal zona fasciculata. Brain Behav. Immun. 2006, 20:460-468.
20. Kubera M., Holan V., Mathison R., Maes M. The effect of repeated amitriptyline and desipramine administration on cytokine release in C57BL/6 mice. Psychoneuroendocrinology 2000, 25:785-797.
21. Kubera M., Lin A.H., Kenis G., Bosmans D., van Bock-Staele D., Maes M. Anti-inflammatory effects of antidepressants through suppression of the interferon-γ/interleukin-10 production ratio. J. Clin. Psychopharmacol. 2001, 21:199-206.
22. Kubera M., Maes M., Holan V., Basta-Kaim A., Roman A., Shani J. Prolonged desipramine treatment increases the production of interleukin-10, an anti-inflammatory cytokine, in C57BL/6 mice subjected to the chronic mild stress model of depression. J. Affect. Disord. 2001, 63:171-178.
23. Kubera M., Grygier B., Arteta B., Urbańska K., Basta-Kaim A., Budziszewska B., Leśkiewicz M., Kołaczkowska E., Maes M., Szczepanik M., Majewska M., Lasoń W. Age-dependent stimulatory effect of desipramine and fluoxetine pretreatment on metastasis formation by B16F10 melanoma in male C57BL/6 mice. Pharmacol. Rep. 2009, 61:1113-1126.
24. Kubera M., Grygier B., Wrona D., Rogóz Z., Roman A., Basta-Kaim A., Budziszewska B., Leskiewicz M., Jantas D., Nowak W., Maes M., Lasoń W. Stimulatory effect of antidepressant drug pretreatment on progression of B16F10 melanoma in high-active male and female C57BL/6J mice. J. Neuroimmunol. 2011, 240-241:34-44.
25. Ledeboer A., Breve J.P., Wierinckx A., van der Jagt S., Bristow A.F., Leysen J.E., Tilders F.J., Van Dam A.M. Expression and regulation of interleukin-10 and interleukin-10 receptor in rat astroglial and microglial cells. Eur. J. Neurosci. 2002, 16:1175-1185.
26. Leonard B.E., Myint A. The psychoneuroimmunology of depression. Hum. Psychopharmacol. Clin. Exp. 2009, 24:165-175.
27. + T lymphocytes to increase IL-10 production. J. Immunol. 2001, 167:2060-2067.
28. Majkutewicz I., Myślińska D., Jerzemowska G., Plucińska K., Listowska M., Grembecka B., Podlacha M., Wrona D. Stress-induced differences in the limbic system Fos expression are more pronounced in rats differing in responsiveness to novelty than social position. Brain Res. Bull. 2012, 89:31-40.
29. Malkin C.J., Pugh P.J., Jones R.D., Kapoor D., Channer K.S., Jones T.H. The effects of testosterone replacement on endogenous inflammatory cytokines and lipid profiles in hypogonadal men. J. Clin. Endocrinol. Metab. 2004, 89:3313-3318.
30. Marques F., Sousa J.C., Coppola G., Falcao A.M., Rodrigues A.J., Geschwind D.H., Sousa N., Correia-Neves M., Palh J.A. Kinetic profile of the transcriptome changes induced in the choroid plexus by peripheral inflammation. J. Cereb. Blood Flow Metab. 2009, 29:921-932.
31. Menolascino M.P., Paige S.R., Wengel S.P., Johnson D.R., Frank M.A., Hendricks E.E. Immunoprotective effect of nefazodone and paroxetine in swim stress. Psychoneuroimmunol. Res. Soc. Abstr. 1996, B.50.
32. Mineka S., Watson D., Clark L.A. Comorbidity of anxiety and unipolar mood disorders. Ann. Rev. Psychol. 1998, 49:377-412.
33. Misslin R., Cigrang M. Does neophobia necessarily imply fear or anxiety?. Behav. Processes 1986, 12:45-50.
34. Moore K.W., de Waal Malefyt R., Coffman R.L., O'Garra A. Interleukin-10 and the interleukin-10 receptor. Ann. Rev. Immunol. 2001, 19:683-765.
35. Muigg P., Hoelzl U., Palfrader K., Neumann I., Wigger A., Landgraf R., Singewald N. Altered brain activation pattern associated with drug-induced attenuation of enhanced depression-like behavior in rats bred for high anxiety. Biol. Psychiatry 2007, 61:782-796.
36. Nestler E.J., Barrot M., DiLeone R.J., Eisch A.J., Gold S.J., Monteggia L.M. Neurobiology of depression. Neuron 2002, 34:13-25.
37. Pariante C.M., Miller A.H. Natural killer cell activity in major depression: a prospective study of the in vivo effects of desmethylimipramine treatment. Eur. Neuropsychopharmacol. Suppl. 1995, 83-88.
38. Paxinos G., Watson C. The Rat Brain in Stereotaxic Coordinates 1998, Academic Press, San Diego.
39. Piazza P.V., Deminiere J.M., Le Moal M., Simon H. Factors that predict individual vulnerability to amphetamine self-administration. Science 1989, 245:1511-1513.
40. Piazza P.V., Le Moal M. Glucocorticoids as a biological substrate of reward: physiological and pathophysiological implications. Brain Res. Rev. 1997, 25:359-372.
41. Prut L., Belzung C. The open field as a paradigm to measure the effects of drugs on anxiety-like behaviors: a review. Eur. J. Pharmacol. 2003, 463:3-33.
42. Ramos A., Mormede P. Stress and emotionality: a multidimensional and genetic approach. Neurosci. Biobehav. Rev. 1998, 22:33-57.
43. Raone A., Cassanelli A., Scheggi S., Rauggi R., Danielli B., De Montis M.G. Hypothalamus-pituitary-adrenal modifications consequent to chronic stress exposure in an experimental model of depression in rats. Neuroscience 2007, 146:1734-1742.
44. Roque S., Correia-Neves M., Mesquita A.R., Palha J.A., Sousa N. Interleukin-10: a key cytokine in depression. Cardiovasc. Psych. Neurol. 2009, 10.1155/2009/187894.
45. Rogóz Z., Budziszewska B., Kubera M., Basta-Kaim A., Jaworska-Feil L., Skuza G., Lasoń W. Effects of combined treatment with imipramine and metyrapone on the immobility time, the activity of hypothalamo-pituitary-adrenocortical axis and immunological parameters in the forced swimming test in the rat. J. Physiol. Pharmacol. 2005, 56:49-61.
46. Sheng M., Dougan S.T., McFadden G., Greenberg M.E. Calcium and growth factor pathways of c-fos transcriptional activation require distinct upstream regulatory sequences. Mol. Cell. Biol. 1988, 8:2787-2796.
47. Steingart A.B., Cotterchio M. Do antidepressants cause, promote, or inhibit cancers?. J. Clin. Epidemiol. 1995, 48:1407-1412.
48. Stone E.A., Lehmann M.L., Lin Y., Quartermain D. Reduced evoked fos expression in activity-related brain regions in animal models of behavioral depression. Prog. Neuro-Psychoph. 2007, 31:1196-1207.
49. Vitkovic I., Maeda S., Sternberg E. Anti-inflammatory cytokines: expression and action in the brain. Neuroimmunomodulation 2001, 9:295-312.
50. Walsh R.N., Cummins R.A. The open field test: a critical review. Psychol. Bull. 1976, 83:481-504.
51. Wrona D., Jurkowski M.K., Luszawska D., Tokarski J., Trojniar W. The effects of lateral hypothalamic lesions on peripheral blood natural killer cell cytotoxicity in rats hyper- and hyporesponsive to novelty. Brain Behav. Immun. 2003, 17:453-461.
52. Wrona D., Jurkowski M.K., Tokarski J. Blood and spleen natural killer cell cytotoxicity after exposure to open field stress in rats: the effect of spontaneous locomotor activity. J. Neuroimmunol. 2004, 150:88-97.
53. Wrona D., Sukiennik L., Jurkowski M.K., Jurkowlaniec E., Glac W., Tokarski J. Effects of amphetamine on NK-related cytotoxicity in rats differing in locomotor reactivity and social position. Brain Behav. Immun. 2005, 19:69-77.
54. You Z., Luo C., Zhang W., Chen Y., He J., Zhao Q., Zuo R., Wu Y. Pro- and anti-inflammatory cytokines expression in rat's brain and spleen exposed to chronic mild stress: involvement in depression. Behav. Brain Res. 2011, 225:135-141.