Ligand-mediated endocytosis of nanoparticles in neural stem cells: Implications for cellular magnetic resonance imaging

Biotechnology Letters

Volumn 35, Issue 12, 2013, Pages 1997-2004

  Zhang, Yesen ^a   Guo, Yongkun ^a   Wu, Bingshan ^b   Zhang, Hongtian ^b   Liu, Chunying ^b   Ma, Jianhua ^b   Dai, Yiwu ^b   Xu, Ruxiang ^b   Yang, Zhijun ^b  

^a ANHUI MEDICAL UNIVERSITY   (China)

^b CHINESE PLA GENERAL HOSPITAL   (China)

Author keywords

Magnetic resonance imaging (MRI); Nanoparticles; Neural stem cells; Reporter gene; Stem cells; Transferrin receptor; Ultra small super paramagnetic iron oxide nanoparticle

Indexed keywords

IRON OXIDE NANOPARTICLE; NEURAL STEM CELL; NEUROLOGICAL DISORDERS; NONINVASIVE METHODS; REPORTER GENE; STEM CELL TRANSPLANTATION; TRANSFERRIN RECEPTORS; WESTERN-BLOT ANALYSIS;

MAGNETIC RESONANCE IMAGING; METAL NANOPARTICLES; NANOPARTICLES; NONINVASIVE MEDICAL PROCEDURES; PARAMAGNETISM; STEM CELLS;

MOLECULAR BIOLOGY;

LENTIVIRUS;

MAGNETITE NANOPARTICLE; TRANSFERRIN; TRANSFERRIN RECEPTOR;

ANIMAL; ARTICLE; CELL CULTURE; CELL SURVIVAL; CHEMISTRY; CYTOLOGY; DRUG EFFECT; ENDOCYTOSIS; GENETIC TRANSFECTION; GENETICS; METABOLISM; METHODOLOGY; MOUSE; NEURAL STEM CELL; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PHYSIOLOGY;

ANIMALS; CELL SURVIVAL; CELLS, CULTURED; ENDOCYTOSIS; MAGNETIC RESONANCE SPECTROSCOPY; MAGNETITE NANOPARTICLES; MICE; NEURAL STEM CELLS; RECEPTORS, TRANSFERRIN; TRANSFECTION; TRANSFERRIN;

EID: 84887318327     PISSN: 01415492     EISSN: 15736776     Source Type: Journal    
DOI: 10.1007/s10529-013-1304-5     Document Type: Article

References (21)

1. Alenzi F, Bahkali A (2011) Stem cells: biology and clinical potential. Afr J Biotechnol 10: 19929-19940.
2. Bakhru SH, Altiok E, Highley C, Delubac D, Suhan J, Hitchens TK, Ho C, Zappe S (2012) Enhanced cellular uptake and long-term retention of chitosan-modified iron-oxide nanoparticles for MRI-based cell tracking. Int J Nanomed 7: 4613-4623.
3. Baum C, von Kalle C, Staal FJ, Li Z, Fehse B, Schmidt M, Weerkamp F, Karlsson S, Wagemaker G, Williams DA (2004) Chance or necessity? Insertional mutagenesis in gene therapy and its consequences. Mol Ther 9: 5-13.
4. Bourrinet P, Bengele HH, Bonnemain B, Dencausse A, Idee JM, Jacobs PM, Lewis JM (2006) Preclinical safety and pharmacokinetic profile of ferumoxtran-10, an ultra-small super-paramagnetic iron oxide magnetic resonance contrast agent. Invest Radiol 41: 313-324.
5. Habashy HO, Powe DG, Staka CM, Rakha EA, Ball G, Green AR, Aleskandarany M, Paish EC, Douglas Macmillan R, Nicholson RI, Ellis IO, Gee JM (2010) Transferrin receptor (cd71) is a marker of poor prognosis in breast cancer and can predict response to tamoxifen. Breast Cancer Res Treat 119: 283-293.
6. Hu FQ, Wei L, Gao MY et al (2006) Preparation of biocompatible magnetite nanocrystals for in vivo magnetic resonance detection of cancer. Adv Mater 18: 2553-2556.
7. MacKlis JD, Magavi SS, Leavitt BR (2000) Induction of neurogenesis in the neocortex of adult mice. Nature 405: 951-955.
8. Moore A, Basilion JP, Chiocca EA, Weissleder R (1998) Measuring transferrin receptor gene expression by NMR imaging. Biochim Biophys Acta 1402: 239-249.
9. Moos T, Rosengren Nielsen T, Skjørringe T, Morgan EH (2007) Iron trafficking inside the brain. J Neurochem 103: 1730-1740.
10. Pitek AS, Mahon E, Monopoli MP et al (2012) Transferrin coated nanoparticles: study of the bionano interface in human plasma. PLoS ONE 7: e40685.
11. Prutki M, Poljak-Blazi M, Jakopovic M, Tomas D, Stipancic I, Zarkovic N (2006) Altered iron metabolism, transferrin receptor 1 and ferritin in patients with colon cancer. Cancer Lett 238: 188-196.
12. Qian ZM, Li H, Sun H, Ho K (2002) Targeted drug delivery via the transferrin receptor-mediated endocytosis pathway. Pharmacol Rev 54: 561-587.
13. Qiao R, Jia Q, Hüwel S, Xia R, Liu T, Gao F, Galla HJ, Gao M (2012) Receptor-mediated delivery of magnetic nanoparticles across the blood-brain barrier. ACS Nano 6: 3304-3310.
14. Ratajczak J, Zuba-Surma E, Paczkowska K, Kucia M, Nowacki P, Ratajczak MZ (2011) Stem cells for neural regeneration-a potential application of very small embryonic-like stem cells. J Physiol Pharmacol 62: 3-12.
15. Recht L, Torres CO, Smith TW, Raso V, Griffin TW (1990) Transferrin receptor in normal and neoplastic brain tissue: implications for brain-tumor immunotherapy. J Neurosurg 72: 941-945.
16. Reynolds BA, Weiss S (1992) Generation of neurons and astrocytes from isolated cells of the adult mammalian central nervous system. Science 255: 1707-1710.
17. Ryschich E, Huszty G, Knaebel HP, Hartel M, Buchler MW, Schmidt J (2004) Transferrin receptor is a marker of malignant phenotype in human pancreatic cancer and in neuroendocrine carcinoma of the pancreas. Eur J Cancer 40: 1418-1422.
18. Sun N, Lee A, Wu JC (2009) Long term non-invasive imaging of embryonic stem cells using reporter genes. Nat Protoc 4: 1192-1201.
19. Tachibanaa Y, Enmib J, Maharaa A, Iidab H, Yamaoka T (2010) Design and characterization of a polymeric MRI contrast agent based on PVA for in vivo living-cell tracking. Contrast Media Mol Imaging 5: 309-317.
20. Wang K, Wang K, Shen B, Huang T, Sun X, Li W, Jin G, Li L, Bu L, Li R, Wang D, Chen X (2010) MR reporter gene imaging of endostatin expression and therapy. Mol Imaging Biol 12: 520-529.
21. Xie H, Zhu Y, Jiang W, Zhou Q, Yang H, Gu N, Xu H, Xu H, Yang X (2011) Lactoferrin-conjugated super-paramagnetic iron oxide nanoparticles as a specific MRI contrast agent for detection of brain glioma in vivo. Biomaterials 32: 495-502.