The Structure of Classical Swine Fever Virus Npro: A Novel Cysteine Autoprotease and Zinc-Binding Protein Involved in Subversion of Type I Interferon Induction

PLoS Pathogens

Volumn 9, Issue 10, 2013, Pages

  Gottipati, Keerthi ^a   Ruggli, Nicolas ^b   Gerber, Markus ^b   Tratschin, Jon Duri ^b   Benning, Matthew ^c   Bellamy, Henry ^d   Choi, Kyung H ^a  

^a University of Texas Medical Branch School of Medicine   (United States)

^b INSTITUTE OF VIROLOGY AND IMMUNOLOGY   (Switzerland)

^c BRUKER AXS INC   (United States)

^d LOUISIANA STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA1 INTERFERON; CYSTEINE PROTEINASE; DISULFIDE; INTERFERON; INTERFERON REGULATORY FACTOR 3; N TERMINAL PROTEASE; UBIQUITIN PROTEIN LIGASE E3; UNCLASSIFIED DRUG; ZINC BINDING PROTEIN;

ARTICLE; CONSENSUS SEQUENCE; CRYSTAL STRUCTURE; CRYSTALLIZATION; DISULFIDE BOND; ENZYME ACTIVE SITE; ENZYME SPECIFICITY; GENE MUTATION; GEOMETRY; HYDROGEN BOND; IMMUNE RESPONSE; INTERFERON INDUCTION; NONHUMAN; NUCLEOTIDE SEQUENCE; PESTIVIRUS; POLYMERASE CHAIN REACTION; PROTEIN CONFORMATION; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN PURIFICATION; PROTEIN STRUCTURE; SEQUENCE ALIGNMENT; UBIQUITINATION; X RAY CRYSTALLOGRAPHY;

ANIMALS; CATALYSIS; CATALYTIC DOMAIN; CLASSICAL SWINE FEVER VIRUS; CRYSTALLOGRAPHY, X-RAY; CYSTEINE PROTEASES; INTERFERON TYPE I; PROTEIN FOLDING; STRUCTURE-ACTIVITY RELATIONSHIP; SWINE;

EID: 84887304158     PISSN: 15537366     EISSN: 15537374     Source Type: Journal    
DOI: 10.1371/journal.ppat.1003704     Document Type: Article

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