β-Glucan antigenemia anticipates diagnosis of blood culture-negative intraabdominal candidiasis: Necessity is the mother of invention

American Journal of Respiratory and Critical Care Medicine

Volumn 188, Issue 9, 2013, Pages 1048-1049

  Jansoniene, Orinta ^a   White, Mary ^a  

^a ROYAL BROMPTON HOSPITAL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIFUNGAL AGENT; BETA GLUCAN;

ABDOMINAL INFECTION; ABDOMINAL SURGERY; ANTIMICROBIAL THERAPY; BLOOD CULTURE; CANDIDA; CARBOHYDRATE ANALYSIS; DIAGNOSTIC ACCURACY; DIAGNOSTIC TEST; DIAGNOSTIC VALUE; EDITORIAL; FUNGUS CULTURE; HUMAN; INVASIVE CANDIDIASIS; POSTOPERATIVE INFECTION; PREDICTIVE VALUE; PRIORITY JOURNAL; SENSITIVITY AND SPECIFICITY;

BETA-GLUCANS; CANDIDIASIS; FEMALE; HUMANS; INTRAABDOMINAL INFECTIONS; MALE;

EID: 84887269959     PISSN: 1073449X     EISSN: 15354970     Source Type: Journal    
DOI: 10.1164/rccm.201309-1612ED     Document Type: Editorial

References (14)

1. Vincent JL, Rello J, Marshall J, Silva E, Anzueto A, Martin CD, Moreno R, Lipman J, Gomersall C, Sakr Y, et al.; EPIC II Group of Investigators. International study of the prevalence and outcomes of infection in intensive care units. JAMA 2009;302:2323-2329.
2. Martin GS, Mannino DM, Eaton S, Moss M. The epidemiology of sepsis in the United States from 1979 through 2000. N Engl J Med 2003;348:1546-1554.
3. Zilberberg MD, Shorr AF, Kollef MH. Secular trends in candidemiarelated hospitalization in the United States, 2000-2005. Infect Control Hosp Epidemiol 2008;29:978-980.
4. Tortorano AM, Kibbler C, Peman J, Bernhardt H, Klingspor L, Grillot R. Candidaemia in Europe: epidemiology and resistance. Int J Antimicrob Agents 2006;27:359-366.
5. Arendrup MC, Bruun B, Christensen JJ, Fuursted K, Johansen HK, Kjaeldgaard P, Knudsen JD, Kristensen L, Møller J, Nielsen L, et al. National surveillance of fungemia in Denmark (2004 to 2009). J Clin Microbiol 2011;49:325-334.
6. Garey KW, RegeM, PaiMP, Mingo DE, Suda KJ, Turpin RS, Bearden DT. Time to initiation of fluconazole therapy impacts mortality in patients with candidemia: a multi-institutional study. Clin Infect Dis 2006;43:25-31.
7. Cuenca-EstrellaM, Verweij PE, ArendrupMC, Arikan-Akdagli S, Bille J, Donnelly JP, Jensen HE, Lass-Flörl C, Richardson MD, Akova M, et al.; ESCMID Fungal Infection Study Group. ESCMID guideline for the diagnosis and management of Candida diseases 2012: diagnostic procedures. Clin Microbiol Infect 2012;18:9-18.
8. León C, Ruiz-Santana S, Saavedra P, Galván B, Blanco A, Castro C, Balasini C, Utande-Vázquez A, González de Molina FJ, Blasco- Navalproto MA, et al.; Cava Study Group. Usefulness of the "Candida score" for discriminating between Candida colonization and invasive candidiasis in non-neutropenic critically ill patients: a prospective multicenter study. Crit Care Med 2009;37:1624-1633.
9. Prella M, Bille J, Pugnale M, Duvoisin B, Cavassini M, Calandra T, Marchetti O. Early diagnosis of invasive candidiasis with mannan antigenemia and antimannan antibodies. Diagn Microbiol Infect Dis 2005;51:95-101.
10. Khot PD, Fredricks DN. PCR-based diagnosis of human fungal infections. Expert Rev Anti Infect Ther 2009;7:1201-1221.
11. Tissot F, Lamoth F, Hauser PM, Orasch C, Flückiger U, Siegemund M, Zimmerli S, Calandra T, Bille J, Eggimann P, et al.; Fungal Infection Network of Switzerland (FUNGINOS). Beta-glucan antigenemia anticipates diagnosis of blood culture-negative intraabdominal candidiasis. Am J Respir Crit Care Med 2013;188:1100-1109.
12. Douglas CM. Fungal beta(1, 3)-D-glucan synthesis. Med Mycol 2001;39: 55-66.
13. Karageorgopoulos DE, Vouloumanou EK, Ntziora F, Michalopoulos A, Rafailidis PI, FalagasME. b-D-glucan assay for the diagnosis of invasive fungal infections: a meta-analysis. Clin Infect Dis 2011;52:750-770.
14. Bouadma L, Luyt CE, Tubach F, Cracco C, Alvarez A, Schwebel C, Schortgen F, Lasocki S, Veber B, Dehoux M, et al.; PRORATA trial group. Use of procalcitonin to reduce patients' exposure to antibiotics in intensive care units (PRORATA trial): a multicentre randomised controlled trial. Lancet 2010;375:463-474.