High-Throughput Bacterial Mutagenicity Testing: Vitotox™ Assay

High-Throughput Screening Methods in Toxicity Testing

Volumn , Issue , 2013, Pages 213-232

  Verschaeve, Luc ^a  

^a SCIENTIFIC INSTITUTE OF PUBLIC HEALTH   (Belgium)

Author keywords

Genotoxicity; Lux operon; SOS induction; Toxicity; Vitotox test

Indexed keywords

EID: 84887249118     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1002/9781118538203.ch11     Document Type: Chapter

References (49)

1. Eastmond, D.A., Hartwig, A., Anderson, D., Anwar, W.A., Cimino, M.C., Dobrev, I., Douglas, G.R., Nohmi, T., Philips, D.H., Vickers, C. (2009). Mutagenicity testing for chemical risk assessment: update of the WHO/IPCS harmonized scheme. Mutagenesis, 24, 341-349.
2. Rao, K.S., Xu, Y., Shaw, E., Parton, J.W. (2004). Mutagenicity testing applied for regulation of developing products. Current Separations, 20, 141-144.
3. Allen, J., Jeffrey, P., Williams, R., Ratcliffe, A.J. (2010). Approaches to assessing drug safety in the discovery phase. Drugs of the Future, 35, 67-75.
4. Bierkens, J., Brits, E., Verschaeve, L. (2005). Environmental monitoring for genotoxic compounds. In: Environmental Toxicity Testing (Thompson, K.C., Wadhia, K., Loibner, A.P., Eds.). Blackwell Publishing Ltd.: Oxford; pp. 229-256.
5. Biran, A., Pedahzur, R., Buchinger, S., Reifferscheid, G., Belkin, S. (2009). Genetically engineered bacteria for genotoxicity assessment. The Handbook of Environmental Chemistry, 5J, 161-186.
6. Ames, B.N., Lee, F.D., Durston, W.E. (1973). An improved bacterial test system for the detection and classification of mutagens and carcinogens. Proceedings of the National Academy of Sciences USA, 70, 782-786.
7. Mortelmans, K., Zeiger, E. (2000). The Ames Salmonella/microsome mutagenicity assay. Mutation Research, 455, 29-60.
8. Quillardet, P., Hofnung, M. (1985). The SOS Chromotest, a colorimetric bacterial assay for genotoxins: procedures. Mutation Research, 147, 65-78.
9. Quillardet, P., Huisman, O., D'Ari, R., Hofnung, M. (1982). SOS chromotest, a direct assay of induction of an SOS function in Escherichia coli K-12 to measure genotoxicity. Proceedings of the National Academy of Sciences USA, 79, 5971-5975.
10. Quillardet, P., de Bellecombe, C., Hofnung, M. (1985). The SOS Chromotest, a colorimetric bacterial assay for genotoxins: validation study with 83 compounds. Mutation Research, 147, 79-95.
11. Oda, Y., Nakamura,S., Oki, I., Kato, T., Shinagawa, H. (1985). Evaluation of the new system (umu-test) for the detection of environmental mutagens and carcinogens. Mutation Research, 147, 219-229.
12. van der Lelie, D., Regniers, L., Borremans, B., Provoost, A., Verschaeve, L. (1997). The VITOTOX test, a SOS-bioluminescence Salmonella typhimurium test to measure genotoxicity kinetics. Mutation Research, 389, 279-290.
13. Verschaeve, L., Van Gompel, J., Regniers, L., Van Parijs, P., van der Lelie, D. (1999). VITOTOX_R genotoxicity and toxicity test for the rapid screening of chemicals. Environmental and Molecular Mutagenesis, 33, 240-248.
14. Rostas, K., Morton, S.J., Picksley, S.M., Lloyd, R.G. (1987). Nucleotide sequence and LexA regulation of the Escherichia coli recN gene. Nucleic Acids Research, 15, 5041-5049.
15. Muto, S., Baba, H., Uno, Y. (2003). Evaluation of the VitotoxTM test as a high-throughput genotoxicity assay. Environmental Mutagen Research, 25, 69-75.
16. Muto, S., Miyata, K., Tsutsumibata, C., Daigo, H., Ooro, T., Sugiura, K., Baba, H., Uno, Y. (2006). A practical application of the VitotoxTM test for genotoxicity screening of pharmaceuticals. In: Topical Issues in Applied Microbiology and Biotechnology (Verschaeve, L., Ed.). Trivandrum, India: Research Signpost; pp. 1-9, ISBN 81-308-01 37-X.
17. Benfenati, E., Benigni, R., DeMarini, D.M., Helma, C., Kirkland, D., Martin, T.M., Mazzatorta, P., Oúedraogo-Arras, G., Richard, A.M., Schilter, B., Schoonen, W.G.E.J., Snyder, R.D., Yang, C. (2009). Predictive models for carcinogenicity and mutagenicity: frameworks, state-of-the-art, and perspectives. Journal of Environmental Science and Health, Part C, 27, 57-90.
18. Schoonen,W.G.E.J.,Westerink,W. M.A., Horbach, G.J. (2009). High-Throughput screening for analysis of in vitro toxicity. In: Molecular, Clinical and Environmental Toxicology, Volume 1: Molecular Toxicology (Luch, A., Ed.). Birkḧauser Verlag Switserland; pp. 401-452.
19. Westerink,W.M.A., Stevenson, J.C.R., Lauwers, A., Griffioen, G., Horbach, G.J., Schoonen, W.G.E.J. (2009). Evaluation of the VitotoxTM and RadarScreen assays for the rapid assessment of genotoxicity in the early research phase of drug development. Mutation Research, 676, 113-130.
20. Kirkland, D., Kasper, P., M̈uller, L., Corvi, R., Speit, G. (2008). Recommended lists of genotoxic and non-genotoxic chemicals for assessment of the performance of new or improved genotoxicity tests: a follow-up to an ECVAM workshop. Mutation Research, 653, 99-108.
21. Kouvelis, V.N., Wang, C., Skrobek, A., Pappas, K.M., Typas, M.A., Butt, T.M. (2011). Assessing the cytotoxic and mutagenic effects of secondary metabolites produced by several fungal biological control agents with the Ames assay and the Vitotox_C test. Mutation Research, 722, 1-6.
22. Corbisier, P., Hansen, P.-D., Barcelo, D., Eds. (2000). Proceedings of the BIOSET technical workshop on genotoxicity biosensing. VITO report 2001/MIT/P053.
23. Pancrazio, J.J., McFadden, P.N., Belkin, S., Marks, R.S. (2004). EILATox-Oregon biomonitoringworkshop: summary and observations. Journal of Applied Toxicology, 24, 317-321.
24. Meril̈ainen, J., Lampinen, J. (2004). ELAITox-Oregon workshop: blind study evaluation ofVitotox test with genotoxic and cytotoxic sample library. Journal of Applied Toxicology, 24, 327-332.
25. Sekler, M.S., Levi, Y., Polyak, B., Novoa, A., Dunlop, P.S.M., Byrne, J.A., Marks, R.S. (2004). Monitoring genotoxicity during the photocatalytic degradation of p-nitrophenol. Journal of Applied Toxicology, 24, 395-400.
26. Brits, E., Schoeters, G., Verschaeve, L. (2004). Genotoxicity of PM10 and extracted organics collected in an industrial, urban and rural area in Flanders, Belgium. Environmental Research, 96, 109-118.
27. Du Four, V.A., Van Larebeke, N., Janssen, C.R. (2004). Genotoxic and mutagenic activity of environmental air samples in Flanders, Belgium. Mutation Research, 558, 155-167.
28. Du Four,V.A., Janssen, C.R., Brits, E.,Van Larebeke, N. (2005). Genotoxic and mutagenic activity of environmental air samples from different rural, urban and industrial sites in Flanders, Belgium. Mutation Research, 588, 106-117.
29. Verschaeve, L. (2005). The VITOTOX_R genotoxicity test. In: Recent Research Developments in Applied Microbiology and Biotechnology (Pandali, S.G., Ed.). Research Signpost: Trivandrum, India; pp. 33-49, ISBN 81-7736-293-3.
30. Vijayashree, B., Ahuja, Y.R, Regniers, L., Verschaeve, L. (2005). Genotoxicity of the Musi river (Hyderabad, India) investigated with the Vitotox_R test. Folia Biologica, 51, 133-139.
31. Brits, E., Regniers, L., Verschaeve, L. (2006). Bacterial genotoxicity tests; Umu-C and VITOTOX test: a comparison with the Ames assay. In: Topical Issues in Applied Microbiology and Biotechnology (Verschaeve, L., Ed.). Research Signpost: Trivandrum, India; pp. 11-21, ISBN 81-308-0137-X.
32. Sparg, S.G.,Kulkarni, M.G., Light, M.E., van Staden, J. (2005). Improving seedling vigour of indigenous medicinal plants with smoke. Bioresource Technology, 96, 1323-1330.
33. Flematti, G.R., Ghisalberti, E.L., Dixon, K.E., Trengove, R.D. (2004). A compound from smoke that promotes seed germination. Science, 305, 977.
34. van Staden, J., Jager, A.K., Light, M.E., Burger, B.V. (2004). Isolation of the major germination cue from plant-derived smoke. South African Journal of Botany, 70, 654-659.
35. Verschaeve, L., Maes, J., Light, M.E., van Staden, J. (2006). Genetic toxicity testing of 3-methyl-2H-furo[2,3-c]pyran-2-one, an important biologically active compound from plant-derived smoke. Mutation Research, 611, 89-95.
36. Jain, N., Soos, V., Balazs, E., van Staden, J. (2008). Changes in cellular macromolecules (DNA, RNA and protein) during seed germination in tomato, following the use of a butenolide, isolated from plant-derived smoke. Plant Growth Regulation, 54, 105-113.
37. Trinh, C., Gevaert, L., Kohout, L., Van Staden, J., Verschaeve, L. (2010). Genotoxicity evaluation of two kinds of smoke water and 3,7-dimethyl-2H-furo[2,3-c]pyran-2-one. Journal of Applied Toxicology, 30, 596-602.
38. Stewart, M.J., Moar, J.J., Steenkamp, V., Kokot, M. (1999). Findings in fatal cases of poisoning attributed to traditional remedies in South Africa. Forensic Science International, 101, 177-183.
39. Thomson, S.A. (2000). South African Government Genocide and Ethnopiracy. The Gaia Research Institute: South Africa.
40. Arora, S., Brits, E., Kaur, S., Kaur, K., Kumar, S., Verschaeve, L. (2005). Evaluation of genotoxicity of medicinal plant extracts by the comet- and VITOTOX test. Journal of Environmental Pathology, Toxicology and Oncology, 24, 193-200.
41. Verschaeve, L., Van Staden, J. (2008). Mutagenic and antimutagenic properties of South African medicinal plant extracts. Journal of Ethnopharmacology, 119, 575-587.
42. van den Bout-van den Beukel, C., Hamza, O.J.M., Moshi, M.J., Matee, M.O.N., Mokx, F., Burger, D.M., Koopmans, P.P., Verweij, P.E., Schoonen,W.G.E.J., van der Ven, A.J.A.M. (2008). Evaluation of cytotoxic, genotoxic and CYP450 enzymatic competition effects of Tanzanian plant extracts traditionally used for treatment of fungal infections. Basic and Clinical Pharmacology and Toxicology, 102, 515-526.
43. Edziri, H., Mastouri, M., Mahjoub, A., Anthonissen, R., Mertens, B., Cammaerts, S., Gevaert, L., Verschaeve, L. (2011). Toxic and mutagenic properties of extracts from Tunisian traditional medicinal plants investigated by the neutral red uptake-, VITOTOXand alkaline comet assays. South African Journal of Botany, 77, 703-710.
44. Chichioco-Hernandez, C., Wudarski, J., Gevaert, L., Verschaeve, L. (2011). Evaluation of cytotoxicity and genotoxicity of some Phillipine medicinal plants. Pharmacognosy Magazine, 7, 171-175.
45. IARC. (2002). IARC Monographs on the Evaluation of Carcinogenic Risks to Humans. Vol. 80; Non Ionizing Radiation, Part 1: Static and Extremely Low-Frequency (ELF) Electric and Magnetic Fields. IARC Press: Lyon, France.
46. Baan, R., Lauby-Secretan, B., El Ghissassi, F. et al. on behalf of the WHO International Agency for Research on Cancer Monograph Working Group. (2011). Carcinogenicity of radiofrequency electromagnetic fields. Lancet Oncology, 12, 624-626.
47. IARC. (2011). IARC Monographs on the Evaluation of Carcinogenic Risks to Humans. Vol. 102; Non Ionizing Radiation, Part 2: Radiofrequency Electromagnetic Fields [includes mobile telephones]. IARC Press: Lyon, France; in press.
48. Verschaeve, L., Anthonissen, R., Gevaert, L., Maes, A. (2011). Genotoxicity investigation of ELF-magnetic fields in Salmonella typhimurium with the sensitive SOS-based VITOTOX test. Bioelectromagnetics, 32, 580-584.
49. Bergqvist, U., Brix, J., de Gruijl, F., de Seze, R., Hietanen, M., Jeffereys, J.G.R., Lagroye, I., Lotz, G.W., Owen, R.D., Repacholi, M.H., Saunders, R., Tenforde, T.S., Verschaeve, L., Veyret, B. (2003). Reviewof experimental investigations of EMF biological effects (0-100 kHz)-ICNIRP Standing committee II. In: Exposure to Static and Low Frequency Electromagnetic Fields, Biological Effects and Health Consequences (Matthes, R., McKinley, A., Bernhardt, J., Vecchia, P., Veyret, B., Eds.). ICNIRP13/2003, ISBN 3-934994-03-2.