Alzheimer disease: [11C]PBB3 - A new PET ligand that identifies tau pathology in the brains of patients with AD

Nature Reviews Neurology

Volumn 9, Issue 11, 2013, Pages 599-

  Wood, Heather ^a  

^a NONE

Author keywords

[No Author keywords available]

Indexed keywords

[11C]PBB3; DIAGNOSTIC AGENT; TAU PROTEIN; UNCLASSIFIED DRUG;

ALZHEIMER DISEASE; BIOACCUMULATION; CLINICAL EFFECTIVENESS; DISEASE ASSOCIATION; DISEASE COURSE; HUMAN; IMAGE ANALYSIS; IN VIVO STUDY; ISOTOPE LABELING; LASER MICROSCOPY; MOLECULAR DYNAMICS; MOLECULAR PATHOLOGY; NEUROIMAGING; NONHUMAN; NOTE; OUTCOME ASSESSMENT; PATIENT ASSESSMENT; POSITRON EMISSION TOMOGRAPHY; PRIORITY JOURNAL; PROTEIN DETERMINATION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; RADIOACTIVITY; SIGNAL DETECTION; ANIMAL; BRAIN; FEMALE; MALE; METABOLISM; PATHOLOGY; TAUOPATHY;

ALZHEIMER DISEASE; ANIMALS; BRAIN; FEMALE; HUMANS; MALE; TAU PROTEINS; TAUOPATHIES;

EID: 84887246247     PISSN: 17594758     EISSN: 17594766     Source Type: Journal    
DOI: 10.1038/nrneurol.2013.216     Document Type: Note

References (3)

1. Maruyama, M. et al. Imaging of tau pathology in a tauopathy mouse model and in Alzheimer patients compared to normal controls. Neuron 79, 1094-1108 (2013)
2. Zhang, W. et al. A highly selective and specific PET tracer for imaging of tau pathologies. J. Alzheimers Dis. 31, 601-612 (2012
3. Chien, D. T. et al. Early clinical PET imaging results with the novel PHF-tau radioligand [F-18]-T807. J. Alzheimers Dis. 34, 457-468 (2013)