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Volumn 18, Issue 3, 2013, Pages 169-174

In vivo investigation of anti-diabetic properties of ripe onion juice in normal and streptozotocin-induced diabetic rats

Author keywords

Anti diabetic; Endoplasmic Reticulum stress; Hypoglycemic effect; Onion; Streptozotocin

Indexed keywords


EID: 84887217855     PISSN: 22871098     EISSN: 22878602     Source Type: Journal    
DOI: 10.3746/pnf.2013.18.3.169     Document Type: Article
Times cited : (21)

References (29)
  • 1
    • 1842334456 scopus 로고    scopus 로고
    • Report of the expert committee on the diagnosis and classification of diabetes mellitus
    • The Expert Committee on the Diagnosis and Classification of Diabetes Mellitus
    • The Expert Committee on the Diagnosis and Classification of Diabetes Mellitus. 1997. Report of the expert committee on the diagnosis and classification of diabetes mellitus. Diabetes Care 20: 1183-1197.
    • (1997) Diabetes Care , vol.20 , pp. 1183-1197
  • 2
    • 0030724591 scopus 로고    scopus 로고
    • Pathogenesis of type 2 diabetes: Metabolic and molecular implications for identifying diabetes genes
    • DeFronzo RA. 1997. Pathogenesis of type 2 diabetes: metabolic and molecular implications for identifying diabetes genes. Diabetes Rev 5: 177-269.
    • (1997) Diabetes Rev , vol.5 , pp. 177-269
    • Defronzo, R.A.1
  • 3
    • 31344441135 scopus 로고    scopus 로고
    • Plant foods in the management of diabetes mellitus: Spices as beneficial antidiabetic food adjuncts
    • Srinivasan K. 2005. Plant foods in the management of diabetes mellitus: spices as beneficial antidiabetic food adjuncts. Int J Food Sci Nutr 56: 399-414.
    • (2005) Int J Food Sci Nutr , vol.56 , pp. 399-414
    • Srinivasan, K.1
  • 4
    • 0000923643 scopus 로고
    • The isolation of S-methyl- L-cysteine sulphoxide and S-n-propyl-L- cysteine sulphoxide from onion (Allium cepa) and the antibiotic activity of crushed onion
    • Virtanen AL, Matikkala EJ. 1976. The isolation of S-methyl- L-cysteine sulphoxide and S-n-propyl-L-cysteine sulphoxide from onion (Allium cepa) and the antibiotic activity of crushed onion. Acta Chem Scand 13: 1898-1900.
    • (1976) Acta Chem Scand , vol.13 , pp. 1898-1900
    • Virtanen, A.L.1    Matikkala, E.J.2
  • 5
    • 0001704785 scopus 로고
    • The chemistry of garlic and onions
    • Block E. 1985. The chemistry of garlic and onions. Sci Am 252: 94-99.
    • (1985) Sci Am , vol.252 , pp. 94-99
    • Block, E.1
  • 6
    • 0028854478 scopus 로고
    • Distribution of quercetin contents in different rings various coloured onion (Allium cepa L.) cultivars
    • Patil BS, Pike LM. 1995. Distribution of quercetin contents in different rings various coloured onion (Allium cepa L.) cultivars. J Hortic Sci 70: 643-650.
    • (1995) J Hortic Sci , vol.70 , pp. 643-650
    • Patil, B.S.1    Pike, L.M.2
  • 8
    • 0020964874 scopus 로고
    • Onion and garlic oils inhibit tumor promotion
    • Belman S. 1983. Onion and garlic oils inhibit tumor promotion. Carcinogenesis 4: 1063-1065.
    • (1983) Carcinogenesis , vol.4 , pp. 1063-1065
    • Belman, S.1
  • 9
    • 1842478282 scopus 로고    scopus 로고
    • Consumption of foods rich in flavonoids is related to a decreased cardiovascular risk in apparently healthy French women
    • Mennen LI, Sapinho D, de Bree A, Arnault N, Bertrais S, Galan P, Hercberg S. 2004. Consumption of foods rich in flavonoids is related to a decreased cardiovascular risk in apparently healthy French women. J Nutr 134: 923-926.
    • (2004) J Nutr , vol.134 , pp. 923-926
    • Mennen, L.I.1    Sapinho, D.2    De Bree, A.3    Arnault, N.4    Bertrais, S.5    Galan, P.6    Hercberg, S.7
  • 10
    • 2142856174 scopus 로고    scopus 로고
    • Antihypertensive effects of onion on NO synthase inhibitor-induced hypertensive rats and spontaneously hypertensive rats
    • Sakai Y, Murakami T, Yamamoto Y. 2003. Antihypertensive effects of onion on NO synthase inhibitor-induced hypertensive rats and spontaneously hypertensive rats. Biosci Biotechnol Biochem 67: 1305-1311.
    • (2003) Biosci Biotechnol Biochem , vol.67 , pp. 1305-1311
    • Sakai, Y.1    Murakami, T.2    Yamamoto, Y.3
  • 11
    • 33845978046 scopus 로고    scopus 로고
    • Lipid lowering effect of S-methyl cysteine sulfoxide from Allium cepa Linn in high cholesterol diet fed rats
    • Kumari K, Augusti KT. 2007. Lipid lowering effect of S-methyl cysteine sulfoxide from Allium cepa Linn in high cholesterol diet fed rats. J Ethnopharmacol 109: 367-371.
    • (2007) J Ethnopharmacol , vol.109 , pp. 367-371
    • Kumari, K.1    Augusti, K.T.2
  • 12
    • 0030661631 scopus 로고    scopus 로고
    • Influence of dietary capsaicin and onion on the metabolic abnormalities associated with streptozotocin induced diabetes mellitus
    • Babu PS, Srinivasan K. 1997. Influence of dietary capsaicin and onion on the metabolic abnormalities associated with streptozotocin induced diabetes mellitus. Mol Cell Biochem 175: 49-57.
    • (1997) Mol Cell Biochem , vol.175 , pp. 49-57
    • Babu, P.S.1    Srinivasan, K.2
  • 13
    • 0029247886 scopus 로고
    • Antidiabetic and hypolipidemic effects of S-methyl cysteine sulfoxide isolated from Allium cepa Linn
    • Kumari K, Mathew BC, Augusti KT. 1995. Antidiabetic and hypolipidemic effects of S-methyl cysteine sulfoxide isolated from Allium cepa Linn. Indian J Biochem Biophys 32: 49-54.
    • (1995) Indian J Biochem Biophys , vol.32 , pp. 49-54
    • Kumari, K.1    Mathew, B.C.2    Augusti, K.T.3
  • 14
    • 0036727118 scopus 로고    scopus 로고
    • Antidiabetic and antioxidative effects of S-methyl cysteine sulfoxide isolated from onions (Allium cepa Linn) as compared to standard drugs in alloxan diabetic rats
    • Kumari K, Augusti KT. 2002. Antidiabetic and antioxidative effects of S-methyl cysteine sulfoxide isolated from onions (Allium cepa Linn) as compared to standard drugs in alloxan diabetic rats. Indian J Exp Biol 40: 1005-1009.
    • (2002) Indian J Exp Biol , vol.40 , pp. 1005-1009
    • Kumari, K.1    Augusti, K.T.2
  • 15
    • 9644289401 scopus 로고    scopus 로고
    • Biochemical study on the hypoglycemic effects of onion and garlic in alloxan-induced diabetic rats
    • El-Demerdash FM, Yousef MI, El-Naga NI. 2005. Biochemical study on the hypoglycemic effects of onion and garlic in alloxan-induced diabetic rats. Food Chem Toxicol 43: 57-63.
    • (2005) Food Chem Toxicol , vol.43 , pp. 57-63
    • El-Demerdash, F.M.1    Yousef, M.I.2    El-Naga, N.I.3
  • 16
    • 0038045416 scopus 로고    scopus 로고
    • Hypoglycemic and antioxidant effects of onion, Allium cepa: Dietary onion addition, antioxidant activity and hypoglycemic effects on diabetic rats
    • Campos KE, Diniz YS, Cataneo AC, Faine LA, Alves MJ, Novelli EL. 2003. Hypoglycemic and antioxidant effects of onion, Allium cepa: dietary onion addition, antioxidant activity and hypoglycemic effects on diabetic rats. Int J Food Sci Nutr 54: 241-246.
    • (2003) Int J Food Sci Nutr , vol.54 , pp. 241-246
    • Campos, K.E.1    Diniz, Y.S.2    Cataneo, A.C.3    Faine, L.A.4    Alves, M.J.5    Novelli, E.L.6
  • 17
    • 22144446730 scopus 로고    scopus 로고
    • Effect of fenugreek, onion and garlic on blood glucose and histopathology of pancreas of alloxan-induced diabetic rats
    • Jelodar GA, Maleki M, Motadayen MH, Sirus S. 2005. Effect of fenugreek, onion and garlic on blood glucose and histopathology of pancreas of alloxan-induced diabetic rats. Indian J Med Sci 59: 64-69.
    • (2005) Indian J Med Sci , vol.59 , pp. 64-69
    • Jelodar, G.A.1    Maleki, M.2    Motadayen, M.H.3    Sirus, S.4
  • 18
    • 0029081239 scopus 로고
    • Anti-diabetic effects of onion and garlic sulfoxide amino acids in rats
    • Sheela CG, Kumud K, Augusti KT. 1995. Anti-diabetic effects of onion and garlic sulfoxide amino acids in rats. Planta Med 61: 356-357.
    • (1995) Planta Med , vol.61 , pp. 356-357
    • Sheela, C.G.1    Kumud, K.2    Augusti, K.T.3
  • 19
    • 0017179001 scopus 로고
    • Streptozotocin-induced pancreatic insulities: New model of diabetes mellitus
    • Like AA, Rossini AA. 1976. Streptozotocin-induced pancreatic insulities: new model of diabetes mellitus. Science 193: 415-417.
    • (1976) Science , vol.193 , pp. 415-417
    • Like, A.A.1    Rossini, A.A.2
  • 20
    • 0034662490 scopus 로고    scopus 로고
    • Effect of punica granatum L. (flowers) on blood glucose level in normal and alloxan induced diabetic rats
    • Jafari MA, Aslam M, Javad K, Singh S. 2000. Effect of Punica granatum L. (flowers) on blood glucose level in normal and alloxan induced diabetic rats. J Ethnopharmacol 70: 309-314.
    • (2000) J Ethnopharmacol , vol.70 , pp. 309-314
    • Jafari, M.A.1    Aslam, M.2    Javad, K.3    Singh, S.4
  • 22
    • 31344449023 scopus 로고
    • Effect of oral administration of raw onion on glucose tolerance test of diabetics: A comparison with tolbutamide
    • Bhushan S. 1984. Effect of oral administration of raw onion on glucose tolerance test of diabetics: a comparison with tolbutamide. Curr Med Pract 28: 712-715.
    • (1984) Curr Med Pract , vol.28 , pp. 712-715
    • Bhushan, S.1
  • 23
    • 84887220692 scopus 로고    scopus 로고
    • Hypoglycemic activity and regeneration of pancreatic beta-cells produced by Allium cepa in alloxan-induced diabetic rats
    • Eldin IMT, Ahmed EM, Abd Elwahab HM. 2009. Hypoglycemic activity and regeneration of pancreatic beta-cells produced by Allium cepa in alloxan-induced diabetic rats. Omdurman Journal of Pharmaceutical 1: 562-568.
    • (2009) Omdurman Journal of Pharmaceutical , vol.1 , pp. 562-568
    • Eldin, I.M.T.1    Ahmed, E.M.2    Abd Elwahab, H.M.3
  • 24
    • 85073262807 scopus 로고    scopus 로고
    • Preliminary study of the clinical hypoglycemic effects of Allium cepa (red onion) in type 1 and type 2 diabetic patients
    • Taj Eldin IM, Ahmed EM, Elwahab HMA. 2010. Preliminary study of the clinical hypoglycemic effects of Allium cepa (red onion) in type 1 and type 2 diabetic patients. Environ Health Insights 4: 71-77.
    • (2010) Environ Health Insights , vol.4 , pp. 71-77
    • Taj Eldin, I.M.1    Ahmed, E.M.2    Elwahab, H.M.A.3
  • 25
    • 79952197919 scopus 로고    scopus 로고
    • Effects of a multi-herbal extract on type 2 diabetes
    • Yeo J, Kang YM, Cho, SI, Jung MH. 2011. Effects of a multi-herbal extract on type 2 diabetes. Chin Med 6: 10.
    • (2011) Chin Med , vol.6 , pp. 10
    • Yeo, J.1    Kang, Y.M.2    Cho, S.I.3    Jung, M.H.4
  • 26
    • 70449494871 scopus 로고    scopus 로고
    • Endoplasmic reticulum stress in beta-cells and development of diabetes
    • Fonseca SG, Burcin M, Gromada J, Urano F. 2009. Endoplasmic reticulum stress in beta-cells and development of diabetes. Curr Opin Pharmacol 9: 763-770.
    • (2009) Curr Opin Pharmacol , vol.9 , pp. 763-770
    • Fonseca, S.G.1    Burcin, M.2    Gromada, J.3    Urano, F.4
  • 27
    • 0242609973 scopus 로고    scopus 로고
    • Impact of endoplasmic reticulum stress pathway on pancreatic â-cells and diabetes mellitus
    • Araki E, Oyadomari S, Mori M. 2003. Impact of endoplasmic reticulum stress pathway on pancreatic â-cells and diabetes mellitus. Exp Biol Med 228: 1213-1217.
    • (2003) Exp Biol Med , vol.228 , pp. 1213-1217
    • Araki, E.1    Oyadomari, S.2    Mori, M.3
  • 28
    • 77957311822 scopus 로고    scopus 로고
    • The unfolded protein response is required to maintain the integrity of the endoplasmic reticulum, prevent oxidative stress and preserve differentiation in â-cells
    • Kaufman RJ, Back SH, Song B, Han J, Hassler J. 2010. The unfolded protein response is required to maintain the integrity of the endoplasmic reticulum, prevent oxidative stress and preserve differentiation in â-cells. Diabetes Obes Metab 1: 99-107.
    • (2010) Diabetes Obes Metab , vol.1 , pp. 99-107
    • Kaufman, R.J.1    Back, S.H.2    Song, B.3    Han, J.4    Hassler, J.5
  • 29
    • 0033994860 scopus 로고    scopus 로고
    • Garlic and onions: Their effect on eicosanoid metabolism and its clinical relevance
    • Ali M, Thomson M, Afzal M. 2000. Garlic and onions: their effect on eicosanoid metabolism and its clinical relevance. Prostaglandins Leukot Essent Fatty Acids 62: 55-73.
    • (2000) Prostaglandins Leukot Essent Fatty Acids , vol.62 , pp. 55-73
    • Ali, M.1    Thomson, M.2    Afzal, M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.