Liquid chromatographic-mass spectrometric method for simultaneous determination of small organic acids potentially contributing to acidosis in severe malaria

Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences

Volumn 941, Issue , 2013, Pages 116-122

  Sriboonvorakul, Natthida ^a,b   Leepipatpiboon, Natchanun ^a   Dondorp, Arjen M ^b,c   Pouplin, Thomas ^c,d   White, Nicholas J ^b,c   Tarning, Joel ^b,c   Lindegardh, Niklas ^b,c  

^a CHULALONGKORN UNIVERSITY   (Thailand)

^b MAHIDOL UNIVERSITY   (Thailand)

^c UNIVERSITY OF OXFORD   (United Kingdom)

^d OXFORD UNIVERSITY CLINICAL RESEARCH UNIT   (Viet Nam)

Author keywords

Acidosis; Bio analysis; Liquid chromatography; Mass spectrometry; Severe malaria; Unidentified acids

Indexed keywords

DISEASES; HYDROPHILICITY; LACTIC ACID; LIQUIDS; MASS SPECTROMETRY; ORGANIC POLYMERS; PHASE SEPARATION;

ACIDOSIS; BIOANALYSIS; FOOD AND DRUG ADMINISTRATION; HYDROPHILIC INTERACTION LIQUID CHROMATOGRAPHIES; QUALITATIVE AND QUANTITATIVE ASSESSMENTS; RELATIVE STANDARD DEVIATIONS; SEVERE MALARIA; SIMULTANEOUS DETERMINATIONS;

LIQUID CHROMATOGRAPHY;

2 HYDROXYBUTYRATE DEHYDROGENASE; 2 OXOGLUTARIC ACID; 3 HYDROXYBUTYRATE DEHYDROGENASE; 4 HYDROXYPHENYLLACTIC ACID; CARBOXYLIC ACID; ETHYLMALONIC ACID; LACTIC ACID; MALONIC ACID; METHYLMALONIC ACID; UNCLASSIFIED DRUG;

ANION EXCHANGE; ARTICLE; CHEMICAL STRUCTURE; ELUTION; HUMAN; HYDROPHILIC INTERACTION CHROMATOGRAPHY; MALARIA FALCIPARUM; MASS SPECTROMETRY; METABOLIC ACIDOSIS; PRIORITY JOURNAL; SOLID PHASE EXTRACTION; URINALYSIS;

ACIDOSIS; BIO-ANALYSIS; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; SEVERE MALARIA; UNIDENTIFIED ACIDS;

ACIDOSIS; ACIDS; CALIBRATION; CHROMATOGRAPHY, LIQUID; HUMANS; LIMIT OF DETECTION; MALARIA; MASS SPECTROMETRY; ORGANIC CHEMICALS; REFERENCE STANDARDS; REPRODUCIBILITY OF RESULTS;

EID: 84887194249     PISSN: 15700232     EISSN: 1873376X     Source Type: Journal    
DOI: 10.1016/j.jchromb.2013.10.005     Document Type: Article

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