-
1
-
-
0036801150
-
Asymmetric Numb distribution is critical for asymmetric cell division of mouse cerebral cortical stem cells and neuroblasts
-
Shen Q., Zhong W., Jan Y.N., Temple S. Asymmetric Numb distribution is critical for asymmetric cell division of mouse cerebral cortical stem cells and neuroblasts. Development 2002, 129:485-4843.
-
(2002)
Development
, vol.129
, pp. 485-4843
-
-
Shen, Q.1
Zhong, W.2
Jan, Y.N.3
Temple, S.4
-
2
-
-
79956291286
-
Numb modulates intestinal epithelial cells toward goblet cell phenotype by inhibiting the Notch signaling pathway
-
Yang Y., Zhu R., Bai J., Zhang X., Tian Y., Li X., Peng Z., He Y., Chen L., Ji Q., Chen W., Fang D., Wang R. Numb modulates intestinal epithelial cells toward goblet cell phenotype by inhibiting the Notch signaling pathway. Exp. Cell Res. 2011, 317:1640-1648.
-
(2011)
Exp. Cell Res.
, vol.317
, pp. 1640-1648
-
-
Yang, Y.1
Zhu, R.2
Bai, J.3
Zhang, X.4
Tian, Y.5
Li, X.6
Peng, Z.7
He, Y.8
Chen, L.9
Ji, Q.10
Chen, W.11
Fang, D.12
Wang, R.13
-
4
-
-
0032705611
-
Characterization of four mammalian numb protein isoforms. Identification of cytoplasmic and membrane-associated variants of the phosphotyrosine binding domain
-
Dho S.E., French M.B., Woods S.A., McGlade C.J. Characterization of four mammalian numb protein isoforms. Identification of cytoplasmic and membrane-associated variants of the phosphotyrosine binding domain. J. Biol. Chem. 1999, 274:33097-33104.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 33097-33104
-
-
Dho, S.E.1
French, M.B.2
Woods, S.A.3
McGlade, C.J.4
-
5
-
-
0024980213
-
Numb, a gene required in determination of cell fate during sensory organ formation in Drosophila embryos
-
Uemura T., Shepherd S., Ackerman L., Jan L.Y., Jan Y.N. numb, a gene required in determination of cell fate during sensory organ formation in Drosophila embryos. Cell 1989, 58:349-360.
-
(1989)
Cell
, vol.58
, pp. 349-360
-
-
Uemura, T.1
Shepherd, S.2
Ackerman, L.3
Jan, L.Y.4
Jan, Y.N.5
-
6
-
-
33747513134
-
Notch signalling regulates stem cell numbers in vitro and in vivo
-
Androutsellis-Theotokis A., Leker R.R., Soldner F., Hoeppner D.J., Ravin R., Poser S.W., Rueger M.A., Bae S-K., Kittappa R., McKay R.D.G. Notch signalling regulates stem cell numbers in vitro and in vivo. Nature 2006, 442:823-826.
-
(2006)
Nature
, vol.442
, pp. 823-826
-
-
Androutsellis-Theotokis, A.1
Leker, R.R.2
Soldner, F.3
Hoeppner, D.J.4
Ravin, R.5
Poser, S.W.6
Rueger, M.A.7
Bae, S.-K.8
Kittappa, R.9
McKay, R.D.G.10
-
7
-
-
32244436592
-
P53 suppresses the self-renewal of adult neural stem cells
-
Meletis K., Wirta V., Hede S.M., Nister M., Lundeberg J., Frisen J. p53 suppresses the self-renewal of adult neural stem cells. Development 2006, 133:363-369.
-
(2006)
Development
, vol.133
, pp. 363-369
-
-
Meletis, K.1
Wirta, V.2
Hede, S.M.3
Nister, M.4
Lundeberg, J.5
Frisen, J.6
-
8
-
-
57049089995
-
Hedgehog signaling in development and cancer
-
Jiang J., Hui C-c. Hedgehog signaling in development and cancer. Dev. Cell 2008, 15:801-812.
-
(2008)
Dev. Cell
, vol.15
, pp. 801-812
-
-
Jiang, J.1
Hui, C.-C.2
-
9
-
-
78651413366
-
Numb is a negative regulator of HGF dependent cell scattering and Rac1 activation
-
Lau K.M., McGlade C.J. Numb is a negative regulator of HGF dependent cell scattering and Rac1 activation. Exp. Cell Res. 2011, 317:539-551.
-
(2011)
Exp. Cell Res.
, vol.317
, pp. 539-551
-
-
Lau, K.M.1
McGlade, C.J.2
-
10
-
-
33947543233
-
In vitro models of intestinal epithelial cell differentiation
-
Simon-Assmann P., Turck N., Sidhoum-Jenny M., Gradwohl G., Kedinger M. In vitro models of intestinal epithelial cell differentiation. Cell Biol. Toxicol. 2007, 23:241-256.
-
(2007)
Cell Biol. Toxicol.
, vol.23
, pp. 241-256
-
-
Simon-Assmann, P.1
Turck, N.2
Sidhoum-Jenny, M.3
Gradwohl, G.4
Kedinger, M.5
-
11
-
-
79955043762
-
NUMB-ing down cancer by more than just a NOTCH
-
Pece S., Confalonieri S., Romano P.R., Di Fiore P.P. NUMB-ing down cancer by more than just a NOTCH. Biochim. Biophys. Acta 1815, 2011:26-43.
-
(1815)
Biochim. Biophys. Acta
, vol.2011
, pp. 26-43
-
-
Pece, S.1
Confalonieri, S.2
Romano, P.R.3
Di Fiore, P.P.4
-
12
-
-
84873088762
-
Tight junction-related human diseases
-
Sawada N. Tight junction-related human diseases. Pathol. Int. 2013, 63:1-12.
-
(2013)
Pathol. Int.
, vol.63
, pp. 1-12
-
-
Sawada, N.1
-
13
-
-
85120145657
-
Adherens and tight junctions: structure, function and connections to the actin cytoskeleton
-
Hartsock A., Nelson W.J. Adherens and tight junctions: structure, function and connections to the actin cytoskeleton. Biochim. Biophys. Acta 1778, 2008:660-669.
-
(1778)
Biochim. Biophys. Acta
, vol.2008
, pp. 660-669
-
-
Hartsock, A.1
Nelson, W.J.2
-
14
-
-
56749139682
-
The epithelial polarity program: machineries involved and their hijacking by cancer
-
Tanos B., Rodriguez-Boulan E. The epithelial polarity program: machineries involved and their hijacking by cancer. Oncogene 2008, 27:6939-6957.
-
(2008)
Oncogene
, vol.27
, pp. 6939-6957
-
-
Tanos, B.1
Rodriguez-Boulan, E.2
-
15
-
-
85028094075
-
Cell polarity-determining proteins Par-3 and PP-1 are involved in epithelial tight junction defects in coeliac disease
-
Schumann M., Günzel D., Buergel N., Richter J.F., Troeger H., May C., Fromm A., Sorgenfrei D., Daum S., Bojarski C., Heyman M., Zeitz M., Fromm M., Schulzke J.D. Cell polarity-determining proteins Par-3 and PP-1 are involved in epithelial tight junction defects in coeliac disease. Gut 2012, 61:220-228.
-
(2012)
Gut
, vol.61
, pp. 220-228
-
-
Schumann, M.1
Günzel, D.2
Buergel, N.3
Richter, J.F.4
Troeger, H.5
May, C.6
Fromm, A.7
Sorgenfrei, D.8
Daum, S.9
Bojarski, C.10
Heyman, M.11
Zeitz, M.12
Fromm, M.13
Schulzke, J.D.14
-
16
-
-
34347359603
-
Numb and Numbl are required for maintenance of cadherin-based adhesion and polarity of neural progenitors
-
Rasin M.R., Gazula V.R., Breunig J.J., Kwan K.Y., Johnson M.B., Liu-Chen S., Li H.S., Jan L.Y., Jan Y.N., Rakic P., Sestan N. Numb and Numbl are required for maintenance of cadherin-based adhesion and polarity of neural progenitors. Nat. Neurosci. 2007, 10:819-827.
-
(2007)
Nat. Neurosci.
, vol.10
, pp. 819-827
-
-
Rasin, M.R.1
Gazula, V.R.2
Breunig, J.J.3
Kwan, K.Y.4
Johnson, M.B.5
Liu-Chen, S.6
Li, H.S.7
Jan, L.Y.8
Jan, Y.N.9
Rakic, P.10
Sestan, N.11
-
17
-
-
34250820373
-
Numb controls integrin endocytosis for directional cell migration with aPKC and PAR-3
-
Nishimura T., Kaibuchi K. Numb controls integrin endocytosis for directional cell migration with aPKC and PAR-3. Dev. Cell 2007, 13:15-28.
-
(2007)
Dev. Cell
, vol.13
, pp. 15-28
-
-
Nishimura, T.1
Kaibuchi, K.2
-
18
-
-
69249209681
-
Numb regulates cell-cell adhesion and polarity in response to tyrosine kinase signaling
-
Wang Z., Sandiford S., Wu C., Li S.S. Numb regulates cell-cell adhesion and polarity in response to tyrosine kinase signaling. EMBO J. 2009, 28:360-2373.
-
(2009)
EMBO J.
, vol.28
, pp. 360-2373
-
-
Wang, Z.1
Sandiford, S.2
Wu, C.3
Li, S.S.4
-
19
-
-
66849083904
-
The E3 ubiquitin ligase LNX1p80 promotes the removal of claudins from tight junctions in MDCK cells
-
Takahashi S., Iwamoto N., Sasaki H., Ohashi M., Oda Y., Tsukita S., Furuse M. The E3 ubiquitin ligase LNX1p80 promotes the removal of claudins from tight junctions in MDCK cells. J. Cell Sci. 2009, 122:985-994.
-
(2009)
J. Cell Sci.
, vol.122
, pp. 985-994
-
-
Takahashi, S.1
Iwamoto, N.2
Sasaki, H.3
Ohashi, M.4
Oda, Y.5
Tsukita, S.6
Furuse, M.7
-
20
-
-
33845999556
-
Expression of the adaptor protein m-Numb in mouse male germ cells
-
Corallini S., Fera S., Grisanti L., Falciatori I., Muciaccia B., Stefanini M., Vicini E. Expression of the adaptor protein m-Numb in mouse male germ cells. Reproduction 2006, 132:887-897.
-
(2006)
Reproduction
, vol.132
, pp. 887-897
-
-
Corallini, S.1
Fera, S.2
Grisanti, L.3
Falciatori, I.4
Muciaccia, B.5
Stefanini, M.6
Vicini, E.7
-
21
-
-
37749020569
-
Prognostic implications of NUMB immunoreactivity in salivary gland carcinomas
-
Maiorano E., Favia G., Pece S., Resta L., Maisonneuve P., Di Fiore P.P., Capodiferro S., Urbani U., Viale G. Prognostic implications of NUMB immunoreactivity in salivary gland carcinomas. Int. J. Immunopathol. Pharmacol. 2007, 20:779-789.
-
(2007)
Int. J. Immunopathol. Pharmacol.
, vol.20
, pp. 779-789
-
-
Maiorano, E.1
Favia, G.2
Pece, S.3
Resta, L.4
Maisonneuve, P.5
Di Fiore, P.P.6
Capodiferro, S.7
Urbani, U.8
Viale, G.9
-
22
-
-
38049046724
-
NUMB controls p53 tumour suppressor activity
-
Colaluca I.N., Tosoni D., Nuciforo P., Senic-Matuglia F., Galimberti V., Viale G., Pece S., Di Fiore P.P. NUMB controls p53 tumour suppressor activity. Nature 2008, 451:76-80.
-
(2008)
Nature
, vol.451
, pp. 76-80
-
-
Colaluca, I.N.1
Tosoni, D.2
Nuciforo, P.3
Senic-Matuglia, F.4
Galimberti, V.5
Viale, G.6
Pece, S.7
Di Fiore, P.P.8
-
23
-
-
77955654410
-
Numb protein expression correlates with a basal-like phenotype and cancer stem cell markers in primary breast cancer
-
Rennstam K., McMichael N., Berglund P., Honeth G., Hegardt C., Ryden L., Luts L., Bendahl P.O., Hedenfalk I. Numb protein expression correlates with a basal-like phenotype and cancer stem cell markers in primary breast cancer. Breast Cancer Res. Treat. 2010, 122:315-324.
-
(2010)
Breast Cancer Res. Treat.
, vol.122
, pp. 315-324
-
-
Rennstam, K.1
McMichael, N.2
Berglund, P.3
Honeth, G.4
Hegardt, C.5
Ryden, L.6
Luts, L.7
Bendahl, P.O.8
Hedenfalk, I.9
-
24
-
-
33749466490
-
IFN-gamma-induced TNFR2 expression is required for TNF-dependent intestinal epithelial barrier dysfunction
-
Wang F., Schwarz B.T., Graham W.V., Wang Y., Su L., Clayburgh D.R., Abraham C., Turner J.R. IFN-gamma-induced TNFR2 expression is required for TNF-dependent intestinal epithelial barrier dysfunction. Gastroenterology 2006, 131:1153-1163.
-
(2006)
Gastroenterology
, vol.131
, pp. 1153-1163
-
-
Wang, F.1
Schwarz, B.T.2
Graham, W.V.3
Wang, Y.4
Su, L.5
Clayburgh, D.R.6
Abraham, C.7
Turner, J.R.8
-
25
-
-
59849102721
-
Helicobacter pylori dysregulation of gastric epithelial tight junctions by urease-mediated myosin II activation
-
Wroblewski L.E., Shen L., Ogden S., Romero-Gallo J., Lapierre L.A., Israel D.A., Turner J.R., Peek R.M. Helicobacter pylori dysregulation of gastric epithelial tight junctions by urease-mediated myosin II activation. Gastroenterology 2009, 136:236-246.
-
(2009)
Gastroenterology
, vol.136
, pp. 236-246
-
-
Wroblewski, L.E.1
Shen, L.2
Ogden, S.3
Romero-Gallo, J.4
Lapierre, L.A.5
Israel, D.A.6
Turner, J.R.7
Peek, R.M.8
-
26
-
-
0035190213
-
Evidence that increased tyrosine phosphorylation causes disassembly of adherens junctions but does not perturb paracellular permeability in Caco-2 cells
-
Morgado-Díaz J.A., de Souza W. Evidence that increased tyrosine phosphorylation causes disassembly of adherens junctions but does not perturb paracellular permeability in Caco-2 cells. Tissue Cell 2001, 33:500-513.
-
(2001)
Tissue Cell
, vol.33
, pp. 500-513
-
-
Morgado-Díaz, J.A.1
de Souza, W.2
-
27
-
-
4143100246
-
L-Glutamine ameliorates acetaldehyde-induced increase in paracellular permeability in Caco-2 cell monolayer
-
Seth A., Basuroy S., Sheth P., Rao R.K. L-Glutamine ameliorates acetaldehyde-induced increase in paracellular permeability in Caco-2 cell monolayer. Am. J. Physiol. Gastrointest. Liver Physiol. 2004, 287:G510-517.
-
(2004)
Am. J. Physiol. Gastrointest. Liver Physiol.
, vol.287
-
-
Seth, A.1
Basuroy, S.2
Sheth, P.3
Rao, R.K.4
-
28
-
-
84870158833
-
Numb is required for the production of terminal asymmetric cell divisions in the developing mouse retina
-
Kechad A., Jolicoeur C., Tufford A., Mattar P., Chow R.W., Harris W.A., Cayouette M. Numb is required for the production of terminal asymmetric cell divisions in the developing mouse retina. J. Neurosci. 2012, 32:17197-17210.
-
(2012)
J. Neurosci.
, vol.32
, pp. 17197-17210
-
-
Kechad, A.1
Jolicoeur, C.2
Tufford, A.3
Mattar, P.4
Chow, R.W.5
Harris, W.A.6
Cayouette, M.7
-
29
-
-
84861209056
-
Interaction of Notch signaling modulator Numb with α-Adaptin regulates endocytosis of Notch pathway components and cell fate determination of neural stem cells
-
Song Y., Lu B. Interaction of Notch signaling modulator Numb with α-Adaptin regulates endocytosis of Notch pathway components and cell fate determination of neural stem cells. J. Biol. Chem. 2012, 287:17716-17728.
-
(2012)
J. Biol. Chem.
, vol.287
, pp. 17716-17728
-
-
Song, Y.1
Lu, B.2
-
30
-
-
12844282801
-
Fractionation of the epithelial apical junctional complex: reassessment of protein distributions in different substructures
-
Vogelmann R., Nelson W.J. Fractionation of the epithelial apical junctional complex: reassessment of protein distributions in different substructures. Mol. Biol. Cell 2005, 16:701-716.
-
(2005)
Mol. Biol. Cell
, vol.16
, pp. 701-716
-
-
Vogelmann, R.1
Nelson, W.J.2
-
31
-
-
13844308129
-
Mechanism of TNF-α modulation of Caco-2 intestinal epithelial tight junction barrier: role of myosin light-chain kinase protein expression
-
Ma T.Y., Boivin M.A., Ye D., Pedram A., Said H.M. Mechanism of TNF-α modulation of Caco-2 intestinal epithelial tight junction barrier: role of myosin light-chain kinase protein expression. Am. J. Physiol. Gastrointest. Liver Physiol. 2005, 288:G422-430.
-
(2005)
Am. J. Physiol. Gastrointest. Liver Physiol.
, vol.288
-
-
Ma, T.Y.1
Boivin, M.A.2
Ye, D.3
Pedram, A.4
Said, H.M.5
-
33
-
-
67249152713
-
Epithelial tight junctions in intestinal inflammation
-
Schulzke J.D., Ploeger S., Amasheh M., Fromm A., Zeissig S., Troeger H., Richter J., Bojarski C., Chumann S.M., Fromm M. Epithelial tight junctions in intestinal inflammation. Ann. N.Y. Acad. Sci. 2009, 1165:294-300.
-
(2009)
Ann. N.Y. Acad. Sci.
, vol.1165
, pp. 294-300
-
-
Schulzke, J.D.1
Ploeger, S.2
Amasheh, M.3
Fromm, A.4
Zeissig, S.5
Troeger, H.6
Richter, J.7
Bojarski, C.8
Chumann, S.M.9
Fromm, M.10
-
34
-
-
70350437248
-
AMP-activated protein kinase mediates the interferon-γ-induced decrease in intestinal epithelial barrier function
-
Scharl M., Paul G., Barrett K.E., McCole D.F. AMP-activated protein kinase mediates the interferon-γ-induced decrease in intestinal epithelial barrier function. J. Biol. Chem. 2009, 284:27952-27963.
-
(2009)
J. Biol. Chem.
, vol.284
, pp. 27952-27963
-
-
Scharl, M.1
Paul, G.2
Barrett, K.E.3
McCole, D.F.4
-
35
-
-
77951903230
-
Tumor necrosis factor alpha increases epithelial barrier permeability by disrupting tight junctions in Caco-2 cells
-
Cui W., Li L.X., Sun C.M., Wen Y., Zhou Y., Dong Y.L., Liu P. Tumor necrosis factor alpha increases epithelial barrier permeability by disrupting tight junctions in Caco-2 cells. Braz. J. Med. Biol. Res. 2010, 43:330-337.
-
(2010)
Braz. J. Med. Biol. Res.
, vol.43
, pp. 330-337
-
-
Cui, W.1
Li, L.X.2
Sun, C.M.3
Wen, Y.4
Zhou, Y.5
Dong, Y.L.6
Liu, P.7
-
36
-
-
80051651480
-
Differential effects of TNF (TNFSF2) and IFN-γ on intestinal epithelial cell morphogenesis and barrier function in three-dimensional culture
-
(e22967)
-
Juuti-Uusitalo K., Klunder L.J., Sjollema K.A., Mackovicova K., Ohgaki R., Hoekstra D., Dekker J., van Ijzendoorn S.C.D. Differential effects of TNF (TNFSF2) and IFN-γ on intestinal epithelial cell morphogenesis and barrier function in three-dimensional culture. PLoS One 2011, 6:1-12. (e22967).
-
(2011)
PLoS One
, vol.6
, pp. 1-12
-
-
Juuti-Uusitalo, K.1
Klunder, L.J.2
Sjollema, K.A.3
Mackovicova, K.4
Ohgaki, R.5
Hoekstra, D.6
Dekker, J.7
van Ijzendoorn, S.C.D.8
-
37
-
-
39449101285
-
Nonmuscle myosin II moves in new directions
-
Conti M.A., Adelstein R.S. Nonmuscle myosin II moves in new directions. J. Cell Sci. 2008, 121:11-18.
-
(2008)
J. Cell Sci.
, vol.121
, pp. 11-18
-
-
Conti, M.A.1
Adelstein, R.S.2
-
38
-
-
19644382735
-
Differential roles for actin polymerization and a myosin II motor in assembly of the epithelial apical junctional complex
-
Ivanov A.I., Hunt D., Utech M., Nusrat A., Parkos C.A. Differential roles for actin polymerization and a myosin II motor in assembly of the epithelial apical junctional complex. Mol. Biol. Cell 2005, 16:2636-2650.
-
(2005)
Mol. Biol. Cell
, vol.16
, pp. 2636-2650
-
-
Ivanov, A.I.1
Hunt, D.2
Utech, M.3
Nusrat, A.4
Parkos, C.A.5
-
39
-
-
33645867973
-
Microtubules regulate disassembly of epithelial apical junctions
-
Ivanov A.I., McCall I.C., Babbin B., Samarin S.N., Nusrat A., Parkos C.A. Microtubules regulate disassembly of epithelial apical junctions. BMC Cell Biol. 2006, 7:12.
-
(2006)
BMC Cell Biol.
, vol.7
, pp. 12
-
-
Ivanov, A.I.1
McCall, I.C.2
Babbin, B.3
Samarin, S.N.4
Nusrat, A.5
Parkos, C.A.6
|