Multimodal exercises simultaneously stimulating cortical and brainstem pathways after unilateral corticospinal lesion

Brain Research

Volumn 1538, Issue , 2013, Pages 17-25

  Harel, Noam Y ^a,b   Yigitkanli, Kazim ^a   Fu, Yiguang ^a   Cafferty, William B J ^a   Strittmatter, Stephen M ^a  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

Corticospinal tract; Exercise rehabilitation; Pyramidotomy; Reticulospinal; Spinal cord injury

Indexed keywords

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN CORTEX; BRAIN STEM; EXERCISE; FEMALE; HAND GRIP; KINEMATICS; LIMB; MOUSE; NERVE SPROUTING; NONHUMAN; OUTCOME ASSESSMENT; PERFORMANCE; PRIORITY JOURNAL; PYRAMIDAL SIGN; SPINAL CORD; STRENGTH; TRAINING; UNILATERAL CORTICOSPINAL LESION;

MUS;

BDA; BIOTINYLATED DEXTRAN AMINE; BRAINSTEM; BS; CORTICOSPINAL TRACT; CRYM; EXERCISE REHABILITATION; FITC; FLUORESCEIN ISOTHIOCYANATE; MOLECULAR WEIGHT; MW; NGR1; NOGO66-RECEPTOR; NON-TRAINED; NT; PBS; PHOSPHATE-BUFFERED SALINE; PKCΓ; PROTEIN KINASE C-GAMMA; PYRAMIDOTOMY; PYX; RETICULOSPINAL; SPINAL CORD INJURY; Μ-CRYSTALLIN;

ANIMALS; BRAIN STEM; CEREBRAL CORTEX; FEMALE; GAIT; MICE; MICE, INBRED C57BL; MOTOR SKILLS; PHYSICAL CONDITIONING, ANIMAL; PYRAMIDAL TRACTS;

EID: 84887156684     PISSN: 00068993     EISSN: 18726240     Source Type: Journal    
DOI: 10.1016/j.brainres.2013.07.012     Document Type: Article

References (37)

1. B. Alstermark, and J. Ogawa In vivo recordings of bulbospinal excitation in adult mouse forelimb motoneurons J. Neurophysiol. 92 2004 1958 1962
2. B. Alstermark, J. Ogawa, and T. Isa Lack of monosynaptic corticomotoneuronal EPSPs in rats: disynaptic EPSPs mediated via reticulospinal neurons and polysynaptic EPSPs via segmental interneurons J. Neurophysiol. 91 2004 1832 1839
3. M. Ballermann, and K. Fouad Spontaneous locomotor recovery in spinal cord injured rats is accompanied by anatomical plasticity of reticulospinal fibers Eur. J. Neurosci. 23 2006 1988 1996
4. M. Brus-Ramer, J.B. Carmel, S. Chakrabarty, and J.H. Martin Electrical stimulation of spared corticospinal axons augments connections with ipsilateral spinal motor circuits after injury J. Neurosci. 27 2007 13793 13801
5. W.B. Cafferty, and S.M. Strittmatter The Nogo-Nogo receptor pathway limits a spectrum of adult CNS axonal growth J. Neurosci. 26 2006 12242 12250
6. G. Courtine, B. Song, R.R. Roy, H. Zhong, J.E. Herrmann, Y. Ao, J. Qi, V.R. Edgerton, and M.V. Sofroniew Recovery of supraspinal control of stepping via indirect propriospinal relay connections after spinal cord injury Nat. Med. 14 2008 69 74
7. G. Courtine, Y. Gerasimenko, R. van den Brand, A. Yew, P. Musienko, H. Zhong, B. Song, Y. Ao, R.M. Ichiyama, and I. Lavrov Transformation of nonfunctional spinal circuits into functional states after the loss of brain input Nat. Neurosci. 12 2009 1333 1342
8. B.H. Dobkin Motor rehabilitation after stroke, traumatic brain, and spinal cord injury: common denominators within recent clinical trials Curr. Opin. Neurol. 22 2009 563 569
9. P. Duffy, A. Schmandke, J. Sigworth, S. Narumiya, W.B. Cafferty, and S.M. Strittmatter Rho-associated kinase II (ROCKII) limits axonal growth after trauma within the adult mouse spinal cord J. Neurosci. 29 2009 15266 15276
10. P. Duffy, X. Wang, C.S. Siegel, N. Tu, M. Henkemeyer, W.B. Cafferty, and S.M. Strittmatter Myelin-derived ephrinB3 restricts axonal regeneration and recovery after adult CNS injury Proc. Natl. Acad. Sci. USA 109 2012 5063 5068
11. G. Garcia-Alias, S. Barkhuysen, M. Buckle, and J.W. Fawcett Chondroitinase ABC treatment opens a window of opportunity for task-specific rehabilitation Nat. Neurosci. 12 2009 1145 1151
12. R. Grasso, Y.P. Ivanenko, M. Zago, M. Molinari, G. Scivoletto, and F. Lacquaniti Recovery of forward stepping in spinal cord injured patients does not transfer to untrained backward stepping Exp. Brain Res. 157 2004 377 382
13. N.Y. Harel, and S.M. Strittmatter Can regenerating axons recapitulate developmental guidance during recovery from spinal cord injury? Nat. Rev. Neurosci. 7 2006 603 616
14. N.Y. Harel, K.H. Song, X. Tang, and S.M. Strittmatter Nogo receptor deletion and multimodal exercise improve distinct aspects of recovery in cervical spinal cord injury J. Neurotrauma 27 2010 2055 2066
15. E. Jankowska, and S.A. Edgley How can corticospinal tract neurons contribute to ipsilateral movements? A question with implications for recovery of motor functions Neuroscientist 12 2006 67 79
16. K. Keizer, and H.G. Kuypers Distribution of corticospinal neurons with collaterals to the lower brain stem reticular formation in monkey (Macaca fascicularis) Exp. Brain Res. 74 1989 311 318
17. C. Kilkenny, W.J. Browne, I.C. Cuthill, M. Emerson, and D.G. Altman Improving bioscience research reporting: the ARRIVE guidelines for reporting animal research PLoS Biol. 8 2010 e1000412
18. L. Krisa, K.L. Frederick, J.C. Canver, S.K. Stackhouse, J.S. Shumsky, and M. Murray Amphetamine-enhanced motor training after cervical contusion injury J. Neurotrauma 29 2012 971 989
19. S.C. Landis, S.G. Amara, K. Asadullah, C.P. Austin, R. Blumenstein, E.W. Bradley, R.G. Crystal, R.B. Darnell, R.J. Ferrante, and H. Fillit A call for transparent reporting to optimize the predictive value of preclinical research Nature 490 2012 187 191
20. D.S. Magnuson, R.R. Smith, E.H. Brown, G. Enzmann, C. Angeli, P.M. Quesada, and D. Burke Swimming as a model of task-specific locomotor retraining after spinal cord injury in the rat Neurorehabilitation Neural Repair 23 2009 535 545
21. J.H. Martin The corticospinal system: from development to motor control Neuroscientist 11 2005 161 173
22. J.H. Martin Systems neurobiology of restorative neurology and future directions for repair of the damaged motor systems Clin. Neurol. Neurosurg. 114 2012 515 523
23. K. Matsuyama, F. Mori, K. Nakajima, T. Drew, M. Aoki, and S. Mori Locomotor role of the corticoreticular-reticulospinal-spinal interneuronal system Prog. Brain Res. 143 2004 239 249
24. G.A. Metz, and I.Q. Whishaw Cortical and subcortical lesions impair skilled walking in the ladder rung walking test: a new task to evaluate fore- and hindlimb stepping, placing, and co-ordination J. Neurosci. Methods 115 2002 169 179
25. O. Raineteau, and M.E. Schwab Plasticity of motor systems after incomplete spinal cord injury Nat. Rev. Neurosci. 2 2001 263 273
26. R. Reitmeir, E. Kilic, B.S. Reinboth, Z. Guo, A. ElAli, A. Zechariah, U. Kilic, and D.M. Hermann Vascular endothelial growth factor induces contralesional corticobulbar plasticity and functional neurological recovery in the ischemic brain Acta Neuropathol. 123 2011 273 284
27. C.N. Riddle, S.A. Edgley, and S.N. Baker Direct and indirect connections with upper limb motoneurons from the primate reticulospinal tract J. Neurosci. 29 2009 4993 4999
28. E.S. Rosenzweig, G. Courtine, D.L. Jindrich, J.H. Brock, A.R. Ferguson, S.C. Strand, Y.S. Nout, R.R. Roy, D.M. Miller, and M.S. Beattie Extensive spontaneous plasticity of corticospinal projections after primate spinal cord injury Nat. Neurosci. 13 2010 1505 1510
29. C.L. Sadowsky, and J.W. McDonald Activity-based restorative therapies: concepts and applications in spinal cord injury-related neurorehabilitation Dev. Disabil. Res. Rev. 15 2009 112 116
30. S. Sasaki, T. Isa, L.G. Pettersson, B. Alstermark, K. Naito, K. Yoshimura, K. Seki, and Y. Ohki Dexterous finger movements in primate without monosynaptic corticomotoneuronal excitation J. Neurophysiol. 92 2004 3142 3147
31. R.R. Smith, D.A. Burke, A.D. Baldini, A. Shum-Siu, R. Baltzley, M. Bunger, and D.S. Magnuson The Louisville Swim Scale: a novel assessment of hindlimb function following spinal cord injury in adult rats J. Neurotrauma 23 2006 1654 1670
32. P.J. Stapley, and T. Drew The pontomedullary reticular formation contributes to the compensatory postural responses observed following removal of the support surface in the standing cat J. Neurophysiol. 101 2009 1334 1350
33. M.L. Starkey, A.W. Barritt, P.K. Yip, M. Davies, F.P. Hamers, S.B. McMahon, and E.J. Bradbury Assessing behavioural function following a pyramidotomy lesion of the corticospinal tract in adult mice Exp. Neurol. 195 2005 524 539
34. M. Thallmair, G.A. Metz, W.J. Z'Graggen, O. Raineteau, G.L. Kartje, and M.E. Schwab Neurite growth inhibitors restrict plasticity and functional recovery following corticospinal tract lesions Nat. Neurosci. 1 1998 124 131
35. R. van den Brand, J. Heutschi, Q. Barraud, J. DiGiovanna, K. Bartholdi, M. Huerlimann, L. Friedli, I. Vollenweider, E.M. Moraud, and S. Duis Restoring voluntary control of locomotion after paralyzing spinal cord injury Science 336 2012 1182 1185
36. X. Wang, P. Duffy, A.W. McGee, O. Hasan, G. Gould, N. Tu, N.Y. Harel, Y. Huang, R.E. Carson, and D. Weinzimmer Recovery from chronic spinal cord contusion after nogo receptor intervention Ann. Neurol. 70 2011 805 821
37. B. Zaaimi, S.A. Edgley, D.S. Soteropoulos, and S.N. Baker Changes in descending motor pathway connectivity after corticospinal tract lesion in macaque monkey Brain 135 2012 2277 2289