Oil-filled lipid nanoparticles containing 2′-(2-bromohexadecanoyl)-docetaxel for the treatment of breast cancer

Advanced Healthcare Materials

Volumn 2, Issue 11, 2013, Pages 1451-1457

  Feng, Lan ^a   Benhabbour, Soumya R ^a   Mumper, Russell J ^a,b  

^a UNC Hamner Institute for Drug Safety Sciences   (United States)

^b UNIVERSITY OF NORTH CAROLINA   (United States)

Author keywords

Docetaxel; Drug delivery; Ester prodrug; Nanoparticle; Oil filled

Indexed keywords

DISEASES; DRUG DELIVERY; ESTERS; MAMMALS; NANOPARTICLES; SYNTHESIS (CHEMICAL); TARGETED DRUG DELIVERY; TUMORS;

BREAST CANCER; BURST RELEASE; DOCETAXEL; ENTRAPMENT EFFICIENCY; ESTER PRODRUG; LIPID NANOPARTICLES; OIL-FILLED; THERAPEUTIC INDEX;

CONTROLLED DRUG DELIVERY;

2' (2 BROMOHEXADECANOYL)DOCETAXEL; ANTINEOPLASTIC AGENT; DOCETAXEL; ESTERASE; NANOPARTICLE; OIL FILLED LIPID NANOPARTICLE; PRODRUG; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; ARTICLE; BREAST CANCER; CANCER SURVIVAL; CONJUGATION; CONTROLLED STUDY; CYTOTOXICITY; DRUG BLOOD LEVEL; DRUG CYTOTOXICITY; DRUG DELIVERY SYSTEM; DRUG EFFICACY; DRUG MEGADOSE; DRUG POTENTIATION; DRUG RELEASE; DRUG RETENTION; DRUG SYNTHESIS; FEMALE; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; LOW DRUG DOSE; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; SURVIVAL RATE;

DOCETAXEL; DRUG DELIVERY; ESTER PRODRUG; NANOPARTICLE; OIL-FILLED;

ANIMALS; ANTINEOPLASTIC AGENTS; BREAST NEOPLASMS; CELL LINE, TUMOR; FEMALE; HUMANS; KAPLAN-MEIER ESTIMATE; MICE; MICE, INBRED BALB C; NANOPARTICLES; OILS; TAXOIDS; TISSUE DISTRIBUTION; TREATMENT OUTCOME;

EID: 84887149072     PISSN: 21922640     EISSN: 21922659     Source Type: Journal    
DOI: 10.1002/adhm.201300017     Document Type: Article

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