Enhanced drug-loading and therapeutic efficacy of hydrotropic oligomer-conjugated glycol chitosan nanoparticles for tumor-targeted paclitaxel delivery

Journal of Controlled Release

Volumn 172, Issue 3, 2013, Pages 823-831

  Koo, Heebeom ^a   Min, Kyung Hyun ^a,b   Lee, Sang Cheon ^b   Park, Jae Hyung ^c   Park, Kinam ^d   Jeong, Seo Young ^b   Choi, Kuiwon ^a   Kwon, Ick Chan ^a,e   Kim, Kwangmeyung ^a  

^a Korea Institute of Science and Technology   (South Korea)

^b Kyung Hee University   (South Korea)

^c Sungkyunkwan University   (South Korea)

^d PURDUE UNIVERSITY   (United States)

^e Korea University   (South Korea)

Author keywords

Cancer therapy; Drug delivery; Glycol chitosan nanoparticles; Hydrotropic oligomer; Paclitaxel; Tumor targeting

Indexed keywords

CANCER THERAPY; DRUG-LOADING EFFICIENCY; FLUORESCENCE IMAGING; GLYCOL CHITOSAN; NANOPARTICLE STRUCTURES; PACLITAXEL; POLYMERIC NANOPARTICLES; TUMOR-TARGETING;

CELL CULTURE; CHITOSAN; CONJUGATED POLYMERS; DRUG DELIVERY; GLYCOLS; IMAGING TECHNIQUES; NANOPARTICLES; OLIGOMERS; POLYMERS; TUMORS;

LOADING;

CREMOPHOR; GLYCOL CHITOSAN NANOPARTICLE; NANOPARTICLE; OLIGOMER; PACLITAXEL; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG ACCUMULATION; DRUG CYTOTOXICITY; DRUG DELIVERY SYSTEM; DRUG EFFICACY; DRUG EXTRAVASATION; DRUG SOLUBILITY; DRUG TISSUE LEVEL; FEMALE; FLUORESCENCE IMAGING; MOLECULARLY TARGETED THERAPY; MOUSE; NANOENCAPSULATION; NONHUMAN; PRIORITY JOURNAL;

CANCER THERAPY; DRUG DELIVERY; GLYCOL CHITOSAN NANOPARTICLES; HYDROTROPIC OLIGOMER; PACLITAXEL; TUMOR-TARGETING;

ANIMALS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; BREAST; BREAST NEOPLASMS; CELL LINE, TUMOR; CHITOSAN; DRUG CARRIERS; DRUG DELIVERY SYSTEMS; FEMALE; HUMANS; MICE; MICE, NUDE; NANOPARTICLES; PACLITAXEL;

EID: 84887132067     PISSN: 01683659     EISSN: 18734995     Source Type: Journal    
DOI: 10.1016/j.jconrel.2013.08.297     Document Type: Article

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