Are thiazide diuretics safe and effective antihypertensive therapy in kidney transplant recipients?

American Journal of Nephrology

Volumn 38, Issue 4, 2013, Pages 285-291

  Taber, David J ^a   Srinivas, Titte M ^a   Pilch, Nicole A ^b   Meadows, Holly B ^b   Fleming, James N ^b   McGillicuddy, John W ^a   Bratton, Charles F ^a   Thomas, Beje ^a   Chavin, Kenneth D ^a   Baliga, Prabhakar K ^a   Egede, Leonard E ^a  

^a MEDICAL UNIVERSITY OF SOUTH CAROLINA   (United States)

^b MEDICAL UNIVERSITY OF SOUTH CAROLINA   (United States)

Author keywords

Graft survival; Hypertension; Kidney transplant; Thiazides

Indexed keywords

ANGIOTENSIN RECEPTOR ANTAGONIST; ANTIHYPERTENSIVE AGENT; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; CALCIUM CHANNEL BLOCKING AGENT; CYCLOSPORIN; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; MYCOPHENOLIC ACID; TACROLIMUS; THIAZIDE DIURETIC AGENT;

ACUTE GRAFT REJECTION; ADULT; ANTIHYPERTENSIVE THERAPY; ARTICLE; COHORT ANALYSIS; DIASTOLIC BLOOD PRESSURE; DRUG EFFICACY; DRUG SAFETY; FEMALE; FOLLOW UP; GLOMERULUS FILTRATION RATE; GRAFT FAILURE; GRAFT RECIPIENT; GRAFT SURVIVAL; HIGH RISK PATIENT; HOSPITAL READMISSION; HUMAN; HYPERKALEMIA; HYPERTENSION; HYPOKALEMIA; HYPOTENSION; KIDNEY TRANSPLANTATION; LONGITUDINAL STUDY; MAJOR CLINICAL STUDY; MALE; MORTALITY; PRIORITY JOURNAL; RETROSPECTIVE STUDY; SYSTOLIC BLOOD PRESSURE; ACUTE KIDNEY FAILURE; CLINICAL EFFECTIVENESS; EDEMA; PATIENT SAFETY;

ADULT; ANTIHYPERTENSIVE AGENTS; BLOOD PRESSURE; DIABETES COMPLICATIONS; DIURETICS; FEMALE; GLOMERULAR FILTRATION RATE; HUMANS; HYPERKALEMIA; HYPERTENSION; KIDNEY TRANSPLANTATION; LONGITUDINAL STUDIES; MALE; MIDDLE AGED; PATIENT READMISSION; POTASSIUM; RENAL INSUFFICIENCY; RETROSPECTIVE STUDIES; RISK; THIAZIDES; TREATMENT OUTCOME;

EID: 84887091378     PISSN: 02508095     EISSN: 14219670     Source Type: Journal    
DOI: 10.1159/000355135     Document Type: Article

References (27)

1. Organ Procurement and Transplantation Network (OPTN) and Scientific Registry of Transplant Recipients (SRTR): OPTN/SRTR 2010 Annual Data Report. Rockville, US Department of Health and Human Services, http://srtr.transplant. hrsa.gov/annualreports/2011/ (accessed April 21, 2013).
2. Howard RJ, Patton PR, Reed AI, Hemming AW, Van der Werf, et al: The changing causes of graft loss and death after kidney transplantation. Transplantation 2002; 73: 1923-1928.
3. El-Zoghby Z, Stegall M, Lager D, Kremers W, Amer H, et al: Identifying specific causes of kidney allograft loss. Am J Transplant 2009; 9: 527-535.
4. Marasà M, Remuzzi G, Cravedi P: Hypertension after kidney transplantation: an important, but still neglected issue. J Hypertens 2011; 29: 2310-2311.
5. Mangray M, Vella JP: Hypertension after kidney transplant. Am J Kidney Dis 2011; 57: 331-341.
6. Kasiske BL, Anjum S, Shah R, Skogen J, Kandaswamy C, et al: Hypertension after kidney transplantation. Am J Kidney Dis 2004; 43: 1071-1081.
7. Kaufeld J, Schiffer M, Chatzikyrkou C: Pathogenesis and management of hypertension after kidney transplantation. Curr Hypertens Rev 2012; 8: 296-301.
8. Taber DJ, Pilch NA, Meadows HB, McGillicuddy JW, Bratton CF, et al: The impact of cardiovascular disease and risk factor treatment on ethnic disparities in kidney transplant. J Cardiovasc Pharmacol Ther 2013; 18: 243-250.
9. Carpenter MA, Weir MR, Adey DB, House AA, Bostom AG, et al: Inadequacy of cardiovascular risk factor management in chronic kidney transplantation - evidence from the FAVORIT study. Clin Transplant 2012; 26: E438-E446.
10. Chobanian AV, Bakris GL, Black HR, et al: The Seventh Report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure: the JNC 7 report. JAMA 2003; 289: 2560-2572.
11. ALLHAT Officers and Coordinators for the ALLHAT Collaborative Research Group: Major outcomes in high-risk hypertensive patients randomized to angiotensin-converting enzyme inhibitor or calcium channel blocker vs diuretic: the Antihypertensive and Lipid- Lowering Treatment to Prevent Heart Attack Trial (ALLHAT). JAMA 2002; 288: 2981-2997.
12. Rahman M, Ford CE, Cutler JA, Davis BR, Piller LB, et al: Long-term renal and cardiovascular outcomes in Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial (ALLHAT) participants by baseline estimated GFR. Clin J Am Soc Nephrol 2012; 7: 989-1002.
13. Karadsheh F, Weir MR: Thiazide and thiazide- like diuretics: an opportunity to reduce blood pressure in patients with advanced kidney disease. Curr Hypertens Rep 2012; 14: 416-420.
14. Agarwal R, Sinha AD: Thiazide diuretics in advanced chronic kidney disease. J Am Soc Hypertens 2012; 6: 299-308.
15. Gaston RS, Kasiske BL, Fieberg AM, Leduc R, Cosio FC, et al: Use of cardioprotective medications in kidney transplant recipients. Am J Transplant 2009; 9: 1811-1815.
16. Lentine KL, Brennan DC, Schnitzler MA: Incidence and predictors of myocardial infarction after kidney transplantation. J Am Soc Nephrol 2005; 16: 496-506.
17. Pilmore HL, Skeans MA, Snyder JJ, Israni AK, Kasiske BL: Cardiovascular disease medications after renal transplantation: results from the patient outcomes in renal transplantation study. Transplantation 2011; 91: 542-551.
18. Liefeldt L, Budde K: Risk factors for cardiovascular disease in renal transplant recipients and strategies to minimize risk. Transplant Int 2010; 23: 1191-1204.
19. Shah S, Khatri I, Freis ED: Mechanism of antihypertensive effect of thiazide diuretics. Am Heart J 1978; 95: 611-618.
20. Duarte JD, Cooper-DeHoff RM: Mechanisms for blood pressure lowering and metabolic effects of thiazide and thiazide-like diuretics. Expert Rev Cardiovasc Ther 2010; 8: 793-802.
21. Acelajado MC, Pisoni R, Dudenbostel T, Dell'Italia LJ, Cartmill F, et al: Refractory hypertension: definition, prevalence, and patient characteristics. J Clin Hypertens 2012; 14: 7-12.
22. Amraoui F, Bos S, Vogt L, van den Born B: Long-term renal outcome in patients with malignant hypertension: a retrospective cohort study. BMC Nephrol 2012; 13: 71.
23. Morales JM, Marcé n R, del Castillo D, Andres A, Gonzalez-Molina M, et al: Risk factors for graft loss and mortality after renal transplantation according to recipient age: a prospective multicentre study. Nephrol Dial Transplant 2012; 27:iv39-iv46.
24. Stankus V, Hemmelgarn B, Campbell NR, Chen G, McAlister FA, et al: Reducing costs and improving hypertension management. Can J Clin Pharmacol 2009; 16:e151-e155.
25. Frishman WH: Importance of medication adherence in cardiovascular disease and the value of once-daily treatment regimens. Cardiol Rev 2007; 15: 257-263.
26. Iskedjian M, Einarson TR, MacKeigan LD, Shear N, Addis A, et al: Relationship between daily dose frequency and adherence to antihypertensive pharmacotherapy: evidence from a meta-analysis. Clin Ther 2002; 24: 302-316.
27. Arthur JM, Shamim S: Interaction of cyclosporine and FK506 with diuretics in transplant recipients. Kidney Int 2000; 58: 325-330.