Gender variance in childhood and sexual orientation in adulthood: A prospective study

Journal of Sexual Medicine

Volumn 10, Issue 11, 2013, Pages 2723-2733

  Steensma, Thomas D ^a   van der Ende, Jan ^b   Verhulst, Frank C ^b   Cohen Kettenis, Peggy T ^a  

^a VU UNIVERSITY MEDICAL CENTER   (Netherlands)

^b SOPHIA CHILDREN S HOSPITAL   (Netherlands)

Author keywords

Childhood; Gender Discomfort; Gender Variance; Homosexuality; Sexual Orientation

Indexed keywords

ADOLESCENT; ADULT; ADULTHOOD; ARTICLE; BISEXUALITY; CHILD; CHILD BEHAVIOR CHECKLIST; CHILDHOOD; CORRELATIONAL STUDY; FANTASY; FEMALE; GENDER; GENDER IDENTITY; GENDER VARIANCE; HOMOSEXUALITY; HUMAN; MAJOR CLINICAL STUDY; MALE; PRESCHOOL CHILD; PRIORITY JOURNAL; PROSPECTIVE STUDY; SCHOOL CHILD; SEXUAL ORIENTATION; UNCERTAINTY; UNHAPPINESS;

CHILDHOOD; GENDER DISCOMFORT; GENDER VARIANCE; HOMOSEXUALITY; SEXUAL ORIENTATION;

ADOLESCENT; ADULT; CHILD; CHILD, PRESCHOOL; FEMALE; GENDER IDENTITY; HUMANS; MALE; PROSPECTIVE STUDIES; SEXUAL BEHAVIOR; YOUNG ADULT;

EID: 84887089922     PISSN: 17436095     EISSN: 17436109     Source Type: Journal    
DOI: 10.1111/j.1743-6109.2012.02701.x     Document Type: Article

References (54)

1. Bailey JM, Zucker KJ. Childhood sex-typed behavior and sexual orientation: A conceptual analysis and quantitative review. Dev Psychol 1995;31:43-55.
2. Zucker KJ, Mitchell JN, Bradley SJ, Tkachuk J, Cantor JM, Allin SM. The recalled childhood gender identity/gender role questionnaire: Psychometric properties. Sex Roles 2006;54:469-83.
3. Blanchard R. Nonhomosexual gender dysphoria. J Sex Res 1988;24:188-93.
4. Freund K, Langevin R, Satterberg J, Steiner B. Extension of the gender identity scale for male. Arch Sex Behav 1977;6:507-19.
5. Green R. Sexual identity conflict in children and adults. New York: Basic Books; 1974.
6. Smith YL, van Goozen SH, Kuiper AJ, Cohen-Kettenis PT. Transsexual subtypes: Clinical and theoretical significance. Psychiatry Res 2005;137:151-60.
7. Drummond KD, Bradley SJ, Peterson-Badali M, Zucker KJ. A follow-up study of girls with gender identity disorder. Dev Psychol 2008;44:34-45.
8. Wallien MS, Cohen-Kettenis PT. Psychosexual outcome of gender-dysphoric children. J Am Acad Child Adolesc Psychiatry 2008;47:1413-23.
9. Zucker KJ, Bradley SJ. Gender identity disorder and psychosexual problems in children and adolescents. New York: Guilford Press; 1995.
10. Cohen-Bendahan CC, van de Beek C, Berenbaum SA. Prenatal sex-hormone effect on child and adult sex-typed behavior: Methods and findings. Neurosci Biobehav Rev 2005;29:353-84.
11. Coolidge FL, Thede LL, Young SE. The heritability of gender identity disorder in a child and adolescent twin sample. Behav Genet 2002;32:251-7.
12. Iervolino AC, Hines M, Golombok SE, Rust J, Plomin R. Genetic and environmental influences on sex-typed behaviour during the preschool years. Child Dev 2005;76:826-40.
13. van Beijsterveldt CE, Hudziak JJ, Boomsma DI. Genetic and environmental influences on cross-gender behavior and relation to behavior problems: A study of Dutch twins at ages 7 and 10 years. Arch Sex Behav 2006;35:647-58.
14. Allen LS, Gorski RA. Sexual orientation and the size of the anterior commissure in the human brain. Proc Natl Acad Sci U S A 1992;89:7199-202.
15. Swaab DF, Zhou JN, Fodor M, Hofman MA. Sexual differentiation of the human hypothalamus: Differences according to sex, sexual orientation, and transsexuality. In: Elbertz L, ed. Sexual orientation: Toward biological understanding. Westport, CT: Publishers/Greenwood Publishing Group, Inc.; 1997:129-50.
16. Garcia-Falgueras A, Swaab DF. A sex difference in the hypothalamic uncinate nucleus: Relationship to gender identity. Brain 2008;131:3132-46.
17. Kruijver FP, Zhou J, Pool C, Hofman MA, Gooren LJ, Swaab DF. Male-to-female transsexuals have female neuron numbers in a limbic nucleus. J Clin Endocrinol Metab 2000;85:2034-41.
18. Luders E, Sánchez FJ, Gaser C, Toga AW, Narr KL, Hamilton LS, Vilain E. Regional gray matter variation in male-to-female transsexualism. Neuroimage 2009;46:904-7.
19. Grimbos T, Dawood K, Burriss RP, Zucker KJ, Puts DA. Sexual orientation and the second to fourth finger length ratio: A meta-analysis in men and women. Behav Neurosci 2010;124:278-87.
20. Kraemer B, Noll T, Delsignore A, Milos G, Schnyder U, Hepp U. Finger length ratio (2D:4D) and dimensions of sexual orientation. Neuropsychobiology 2006;53:210-4.
21. Schneider HJ, Pickel J, Stalla GK. Typical female 2nd-4th finger length (2D:4D) ratios in male-to-female transsexuals-Possible implications for prenatal androgen exposure. Psychoneuroendocrinology 2006;31:265-9.
22. Wallien MS, Zucker KJ, Steensma TD, Cohen-Kettenis PT. 2D:4D finger-length ratios in children and adults with gender identity disorder. Horm Behav 2008;54:450-4.
23. Ross MW. Retrospective distortion in homosexual research. Arch Sex Behav 1980;9:523-31.
24. McIntosh M. The homosexual role. Soc Probl 1968;16:182-92.
25. Cohler BJ, Galatzer-Levy RM. The course of gay and lesbian lives: Social and psychoanalytic perspectives. Chicago: University of Chicago Press; 2000.
26. Gottschalk L. Same-sex sexuality and childhood gender nonconformity: A spurious connection. J Gend Stud 2003;12:35-50.
27. Bartlett NH, Vasey PL, Bukowski WM. Is gender identity disorder in children a mental disorder? Sex Roles 2000;43:753-85.
28. Cardoso FL. Recalled sex-typed behavior in childhood and sports' preferences in adulthood of heterosexual, bisexual, and homosexual men from Brazil, Turkey, and Thailand. Arch Sex Behav 2008;38:726-36.
29. Safir MP, Rosenmann A, Kloner O. Tomboyism, sexual orientation, and adult gender roles among Israeli women. Sex Roles 2003;48:401-10.
30. Whitam FL, Mathy RM. Childhood cross-gender behavior of homosexual females in Brazil, Peru, the Philippines, and the United States. Arch Sex Behav 1991;20:151-70.
31. Zucker KJ. Cross-gender-identified children. In Steiner, BW, ed. Gender dysphoria: Development, research, management. New York: Plenum Press; 1985:75-174.
32. American Psychiatric Association. Diagnostic and statistical manual of mental disorders, DSM-IV-TR. 4th edition, text revision. Washington, DC: American Psychiatric Association; 2000.
33. Verhulst FC, Akkerhuis GW, Althaus M. Mental health in Dutch children: I. A cross-cultural comparison. Acta Psychiatr Scand Suppl 1985;323:1-108.
34. Bongers IL, Koot HM, van der Ende J, Verhulst FC. Developmental trajectories of externalizing behaviors in childhood and adolescence. Child Dev 2004;75:1523-37.
35. Hofstra MB, van der Ende J, Verhulst FC. Continuity and change of psychopathology from childhood into adolescence: A 14-year follow-up study. J Am Acad Child Adolesc Psychiatry 2000;39:850-8.
36. Van Meurs I, Reef J, Verhulst F, van der Ende J. Intergenerational transmission of child problem behaviors: A longitudinal, population-based study. J Am Acad Child Adolesc Psychiatry 2009;48:138-45.
37. Achenbach TM, Edelbrock CS. Manual for the child behavior checklist and revised child behavior profile. Burlington, VT: University of Vermont, Department of Psychiatry; 1983.
38. Verhulst FC, van der Ende J, Koot HM. Handleiding voor de CBCL/4-18 [Manual for the CBCL/4-18]. Erasmus University, Department of Child and Adolescent Psychiatry, Sophia Children's Hospital: Rotterdam, Netherlands; 1996.
39. Cohen-Kettenis PT, Owen A, Kaijser VG, Bradley SJ, Zucker KJ. Demographic characteristics, social competence, and behavior problems in children with gender identity disorder: A cross-national, cross-clinic comparative analysis. J Abnorm Child Psychol 2003;31:41-53.
40. Kinsey AC, Pomeroy WB, Martin CE. Sexual behavior in the human male. Philadelphia: W.B. Saunders; 1948.
41. Green R. The "sissy boy syndrome" and the development of homosexuality. New Haven, CT: Yale University Press; 1987.
42. Kuyper L. Seksualiteit en seksuele gezondheid bij homo- en biseksuelen [Sexuality and sexual health in homo- and bisexuals]. In: Bakker F, Vanwesenbeeck I, eds. Seksuele gezondheid in Nederland 2006 [Sexual health in the Netherlands 2006]. Delft: Eburon; 2006:167-88.
43. Van Zessen G. Sex en levensloop [Sex over the course of life]. In: van Zessen G, Sandfort T, eds. Seksualiteit in Nedeland [Sexuality in the Netherlands]. Amsterdam: Swets & Zeitlinger; 1991:35-57.
44. Witte BS. Homoseksualiteit [Homosexuality]. In: Noordhoff JD, ed. Sex in Nederland [Sexuality in the Netherlands]. Utrecht: Het Spectrum; 1969:127-47.
45. Bradley SJ, Zucker KJ. Gender identity disorder: A review of the past 10 years. J Am Acad Child Adolesc Psychiatry 1979;36:872-80.
46. Johnson LL, Bradley SJ, Birkenfeld-Adams AS, Kuksis Radzins MA, Maing DM, Mitchell JN, Zucker KJ. A parent-report Gender Identity Questionnaire for Children. Arch Sex Behav 2004;33:105-16.
47. Zucker KJ, Bradley SJ, Lowry Sullivan CB, Kuksis M, Birkenfeld-Adams A, Mitchell JN. A gender identity interview for children. J Pers Assess 1993;61:443-56.
48. Wallien MS, Quilty LC, Steensma TD, Singh D, Lambert SL, Leroux A, Owen-Anderson A, Kibblewhite SJ, Bradley SJ, Cohen-Kettenis PT, Zucker KJ. Cross-national replication of the gender identity interview for children. J Pers Assess 2009;91:545-52.
49. Bakker A, van Kesteren PJ, Gooren LJ, Bezemer PD. The prevalence of transsexualism in the Netherlands. Acta Psychiatr Scand 1993;87:237-8.
50. Lev AI. Disordering gender identity: Gender identity disorder in the DSM-IV-TR. J Psychol Human Sex 2005;17:35-69.
51. Bockting WO, Ehrbar RD. Commentary: DSM Classification of Gender Identity Disorder. J Psychol Human Sex 2005;17:125-34.
52. Hill DB, Rozanski C, Carfagnini J, Willoughby B. Gender identity disorders in childhood and adolescence: A critical inquiry. Int J Sex Health 2007;91:57-75.
53. Wilson I, Griffin C, Wren B. The validity of the diagnosis of gender identity disorder (child and adolescent criteria). Clin Child Psychol Psychiatry 2002;7:335-51.
54. de Vries AL, Cohen-Kettenis PT. Clinical management of gender dysphoria in children and adolescents: The Dutch approach. J Homosex (in press).