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Volumn 33, Issue 11, 2013, Pages

Alteplase treatment does not increase brain injury after mechanical middle cerebral artery occlusion in the rat

Author keywords

alteplase; cerebral ischemia; infarct; L arginine; middle cerebral artery occlusion; recombinant tissue plasminogen activator

Indexed keywords

ALTEPLASE; ARGININE; SODIUM CHLORIDE;

EID: 84887088804     PISSN: 0271678X     EISSN: 15597016     Source Type: Journal    
DOI: 10.1038/jcbfm.2013.148     Document Type: Article
Times cited : (19)

References (32)
  • 1
    • 0019501237 scopus 로고
    • Studies on the specific fibrinolytic effect of human extrinsic (tissue-type) plasminogen activator in human blood and in various animal species in vitro
    • Korninger C, Collen D. Studies on the specific fibrinolytic effect of human extrinsic (tissue-type) plasminogen activator in human blood and in various animal species in vitro. Thromb Haemost 1981; 46: 561-565. (Pubitemid 11049531)
    • (1981) Thrombosis and Haemostasis , vol.46 , Issue.2 , pp. 561-565
    • Korninger, C.1    Collen, D.2
  • 2
    • 0028783948 scopus 로고
    • NINDS. Tissue plasminogen activator for acute ischemic stroke. The national institute of neurological disorders and stroke rt-pa stroke study group
    • NINDS. Tissue plasminogen activator for acute ischemic stroke. The national institute of neurological disorders and stroke rt-pa stroke study group. N Engl J Med 1995; 333: 1581-1587.
    • (1995) N Engl J Med , vol.333 , pp. 1581-1587
  • 3
    • 71849095831 scopus 로고    scopus 로고
    • Stroke treatment with alteplase given 3.0-4.5 hours after onset of acute ischaemic stroke (ecass iii): Additional outcomes and subgroup analysis of a randomised controlled trial
    • Bluhmki E, Chamorro A, Davalos A, Machnig T, Sauce C, Wahlgren N et al. Stroke treatment with alteplase given 3.0-4.5 hours after onset of acute ischaemic stroke (ecass iii): Additional outcomes and subgroup analysis of a randomised controlled trial. Lancet Neurol 2009; 8: 1095-1102.
    • (2009) Lancet Neurol , vol.8 , pp. 1095-1102
    • Bluhmki, E.1    Chamorro, A.2    Davalos, A.3    MacHnig, T.4    Sauce, C.5    Wahlgren, N.6
  • 4
    • 1542315556 scopus 로고    scopus 로고
    • Association of outcome with early stroke treatment: Pooled analysis of atlantis, ecass, and ninds rt-pa stroke trials
    • Hacke W, Donnan G, Fieschi C, Kaste M, von Kummer R, Broderick JP et al. Association of outcome with early stroke treatment: pooled analysis of atlantis, ecass, and ninds rt-pa stroke trials. Lancet 2004; 363: 768-774.
    • (2004) Lancet , vol.363 , pp. 768-774
    • Hacke, W.1    Donnan, G.2    Fieschi, C.3    Kaste, M.4    Von Kummer, R.5    Broderick, J.P.6
  • 5
    • 78049461936 scopus 로고    scopus 로고
    • The contribution of L-arginine to the neurotoxicity of recombinant tissue plasminogen activator following cerebral ischemia: A review of rtpa neurotoxicity
    • Harston GW, Sutherland BA, Kennedy J, Buchan AM. The contribution of L-arginine to the neurotoxicity of recombinant tissue plasminogen activator following cerebral ischemia: A review of rtpa neurotoxicity. J Cereb Blood Flow Metab 2010; 30: 1804-1816.
    • (2010) J Cereb Blood Flow Metab , vol.30 , pp. 1804-1816
    • Harston, G.W.1    Sutherland, B.A.2    Kennedy, J.3    Buchan, A.M.4
  • 7
    • 0031951510 scopus 로고    scopus 로고
    • Tissue plasminogen activator (tPA) increases neuronal damage after focal cerebral ischemia in wild-type and tPA-deficient mice
    • DOI 10.1038/nm0298-228
    • Wang YF, Tsirka SE, Strickland S, Stieg PE, Soriano SG, Lipton SA. Tissue plasminogen activator (tpa) increases neuronal damage after focal cerebral ischemia in wild-type and tpa-deficient mice. Nat Med 1998; 4: 228-231. (Pubitemid 28138083)
    • (1998) Nature Medicine , vol.4 , Issue.2 , pp. 228-231
    • Wang, Y.F.1    Tsirka, S.E.2    Strickland, S.3    Stieg, P.E.4    Soriano, S.G.5    Lipton, S.A.6
  • 8
    • 0033594338 scopus 로고    scopus 로고
    • Tissue plasminogen activator does not increase neuronal damage in rat models of global and focal ischemia
    • Klein GM, Li H, Sun P, Buchan AM. Tissue plasminogen activator does not increase neuronal damage in rat models of global and focal ischemia. Neurology 1999; 52: 1381-1384. (Pubitemid 29190527)
    • (1999) Neurology , vol.52 , Issue.7 , pp. 1381-1384
    • Klein, G.M.1    Li, H.2    Sun, P.3    Buchan, A.M.4
  • 10
    • 0027828715 scopus 로고
    • Stability characterization and formulation development of alteplase, a recombinant tissue plasminogen activator
    • Wang YJ, Pearlman R (eds) Plenum Press: New York
    • Nguyen TH, Ward C. Stability characterization and formulation development of alteplase, a recombinant tissue plasminogen activator. In: Wang YJ, Pearlman R (eds). Stability and CharActerization of Protein and Peptide Drugs: Case Histories. Plenum Press: New York, 1993, pp 91-134.
    • (1993) Stability and CharActerization of Protein and Peptide Drugs: Case Histories , pp. 91-134
    • Nguyen, T.H.1    Ward, C.2
  • 11
    • 0024300153 scopus 로고
    • L-arginine is the physiological precursor for the formation of nitric oxide in endothelium-dependent relaxation
    • Palmer RM, Rees DD, Ashton DS, Moncada S. L-arginine is the physiological precursor for the formation of nitric oxide in endothelium-dependent relaxation. Biochem Biophys Res Commun 1988; 153: 1251-1256.
    • (1988) Biochem Biophys Res Commun , vol.153 , pp. 1251-1256
    • Palmer, R.M.1    Rees, D.D.2    Ashton, D.S.3    Moncada, S.4
  • 12
    • 0031020172 scopus 로고    scopus 로고
    • Bright and dark sides of nitric oxide in ischemic brain injury
    • DOI 10.1016/S0166-2236(96)10074-6, PII S0166223696100746
    • Iadecola C. Bright and dark sides of nitric oxide in ischemic brain injury. Trends Neurosci 1997; 20: 132-139. (Pubitemid 27086729)
    • (1997) Trends in Neurosciences , vol.20 , Issue.3 , pp. 132-139
    • Iadecola, C.1
  • 13
    • 78650874284 scopus 로고    scopus 로고
    • Neuroprotection by dimethyloxalylglycine following permanent and transient focal cerebral ischemia in rats
    • Nagel S, Papadakis M, Chen R, Hoyte LC, Brooks KJ, Gallichan D et al. Neuroprotection by dimethyloxalylglycine following permanent and transient focal cerebral ischemia in rats. J Cereb Blood Flow Metab 2011; 31: 132-143.
    • (2011) J Cereb Blood Flow Metab , vol.31 , pp. 132-143
    • Nagel, S.1    Papadakis, M.2    Chen, R.3    Hoyte, L.C.4    Brooks, K.J.5    Gallichan, D.6
  • 14
    • 0028959038 scopus 로고
    • Neurological deficit and extent of neuronal necrosis attributable to middle cerebral artery occlusion in rats Statistical validation
    • discussion 635
    • Garcia JH, Wagner S, Liu KF, Hu XJ. Neurological deficit and extent of neuronal necrosis attributable to middle cerebral artery occlusion in rats. Statistical validation. Stroke 1995; 26: 627-634, discussion 635.
    • (1995) Stroke , vol.26 , pp. 627-634
    • Garcia, J.H.1    Wagner, S.2    Liu, K.F.3    Hu, X.J.4
  • 17
    • 0345802826 scopus 로고    scopus 로고
    • Delayed Secondary Phase of Peri-Infarct Depolarizations after Focal Cerebral Ischemia: Relation to Infarct Growth and Neuroprotection
    • Hartings JA, Rolli ML, Lu XC, Tortella FC. Delayed secondary phase of peri-infarct depolarizations after focal cerebral ischemia: Relation to infarct growth and neuroprotection. J Neurosci 2003; 23: 11602-11610. (Pubitemid 38021287)
    • (2003) Journal of Neuroscience , vol.23 , Issue.37 , pp. 11602-11610
    • Hartings, J.A.1    Rolli, M.L.2    Lu, X.-C.M.3    Tortella, F.C.4
  • 18
    • 84862629039 scopus 로고    scopus 로고
    • Recombinant tissue plasminogen activator for acute ischaemic stroke: An updated systematic review and meta-analysis
    • Wardlaw JM, Murray V, Berge E, del Zoppo G, Sandercock P, Lindley RL et al. Recombinant tissue plasminogen activator for acute ischaemic stroke: an updated systematic review and meta-analysis. Lancet 2012; 379: 2364-2372.
    • (2012) Lancet , vol.379 , pp. 2364-2372
    • Wardlaw, J.M.1    Murray, V.2    Berge, E.3    Del Zoppo, G.4    Sandercock, P.5    Lindley, R.L.6
  • 19
    • 84876695675 scopus 로고    scopus 로고
    • Complications associated with recombinant tissue plasminogen activator therapy for acute ischaemic stroke
    • Balami JS, Sutherland BA, Buchan AM. Complications associated with recombinant tissue plasminogen activator therapy for acute ischaemic stroke. CNS Neurol Disord Drug Targets 2013; 12: 155-169.
    • (2013) CNS Neurol Disord Drug Targets , vol.12 , pp. 155-169
    • Balami, J.S.1    Sutherland, B.A.2    Buchan, A.M.3
  • 21
    • 46749118298 scopus 로고    scopus 로고
    • Activation of pdgfcc by tissue plasminogen activator impairs blood-brain barrier integrity during ischemic stroke
    • Su EJ, Fredriksson L, Geyer M, Folestad E, Cale J, Andrae J et al. Activation of pdgfcc by tissue plasminogen activator impairs blood-brain barrier integrity during ischemic stroke. Nat Med 2008; 14: 731-737.
    • (2008) Nat Med , vol.14 , pp. 731-737
    • Su, E.J.1    Fredriksson, L.2    Geyer, M.3    Folestad, E.4    Cale, J.5    Andrae, J.6
  • 22
    • 63949085383 scopus 로고    scopus 로고
    • Dissociation and protection of the neurovascular unit after thrombolysis and reperfusion in ischemic rat brain
    • Yamashita T, Kamiya T, Deguchi K, Inaba T, Zhang H, Shang J et al. Dissociation and protection of the neurovascular unit after thrombolysis and reperfusion in ischemic rat brain. J Cereb Blood Flow Metab 2009; 29: 715-725.
    • (2009) J Cereb Blood Flow Metab , vol.29 , pp. 715-725
    • Yamashita, T.1    Kamiya, T.2    Deguchi, K.3    Inaba, T.4    Zhang, H.5    Shang, J.6
  • 23
    • 0035164372 scopus 로고    scopus 로고
    • Effects of recombinant tissue plasminogen activator after intraluminal thread occlusion in mice: Role of hemodynamic alterations
    • Kilic E, Bahr M, Hermann DM. Effects of recombinant tissue plasminogen activator after intraluminal thread occlusion in mice: role of hemodynamic alterations. Stroke 2001; 32: 2641-2647. (Pubitemid 33055319)
    • (2001) Stroke , vol.32 , Issue.11 , pp. 2641-2647
    • Kilic, E.1    Bahr, M.2    Hermann, D.M.3
  • 24
    • 12844276482 scopus 로고    scopus 로고
    • Aggravation of focal cerebral ischemia by tissue plasminogen activator is reversed by 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitor but does not depend on endothelial NO synthase
    • DOI 10.1161/01.STR.0000152273.24063.f7
    • Kilic E, Kilic U, Matter CM, Luscher TF, Bassetti CL, Hermann DM. Aggravation of focal cerebral ischemia by tissue plasminogen activator is reversed by 3-hydroxy-3-methylglutaryl coenzyme a reductase inhibitor but does not depend on endothelial no synthase. Stroke 2005; 36: 332-336. (Pubitemid 40170818)
    • (2005) Stroke , vol.36 , Issue.2 , pp. 332-336
    • Kilic, E.1    Kilic, U.2    Matter, C.M.3    Luscher, T.F.4    Bassetti, C.L.5    Hermann, D.M.6
  • 25
    • 0034117546 scopus 로고    scopus 로고
    • Postischemic attenuation of cerebral artery reactivity is increased in the presence of tissue plasminogen activator
    • Cipolla MJ, Lessov N, Clark WM, Haley Jr. EC. Postischemic attenuation of cerebral artery reactivity is increased in the presence of tissue plasminogen activator. Stroke 2000; 31: 940-945. (Pubitemid 30198443)
    • (2000) Stroke , vol.31 , Issue.4 , pp. 940-945
    • Cipolla, M.J.1    Lessov, N.2    Clark, W.M.3
  • 29
    • 61649086903 scopus 로고    scopus 로고
    • Ttc, fluoro-jade b and neun staining confirm evolving phases of infarction induced by middle cerebral artery occlusion
    • Liu F, Schafer DP, McCullough LD. Ttc, fluoro-jade b and neun staining confirm evolving phases of infarction induced by middle cerebral artery occlusion. J Neurosci Methods 2009; 179: 1-8.
    • (2009) J Neurosci Methods , vol.179 , pp. 1-8
    • Liu, F.1    Schafer, D.P.2    McCullough, L.D.3
  • 31
    • 80052228154 scopus 로고    scopus 로고
    • Cerebral blood flow alteration in neuroprotection following cerebral ischaemia
    • Sutherland BA, Papadakis M, Chen RL, Buchan AM. Cerebral blood flow alteration in neuroprotection following cerebral ischaemia. J Physiol 2011; 589: 4105-4114.
    • (2011) J Physiol , vol.589 , pp. 4105-4114
    • Sutherland, B.A.1    Papadakis, M.2    Chen, R.L.3    Buchan, A.M.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.