Mesenchymal stem cells from osteoporotic patients feature impaired signal transduction but sustained osteoinduction in response to BMP-2 stimulation

Biochemical and Biophysical Research Communications

Volumn 440, Issue 4, 2013, Pages 617-622

  Prall, Wolf Christian ^a   Haasters, Florian ^a   Heggebö, Jostein ^a   Polzer, Hans ^a   Schwarz, Christina ^a   Gassner, Christoph ^a   Grote, Stefan ^a   Anz, David ^a   Jäger, Marcus ^b   Mutschler, Wolf ^a   Schieker, Matthias ^a  

^a UNIVERSITY OF MUNICH   (Germany)

^b UNIVERSITY OF DUISBURG ESSEN   (Germany)

Author keywords

BMP 2; Mesenchymal stem cells; Osteogenic differentiation; Osteoporosis; Signal transduction

Indexed keywords

BONE MORPHOGENETIC PROTEIN 2; OSTEOCALCIN; SMAD1 PROTEIN; SMAD5 PROTEIN; SMAD8 PROTEIN; TRANSCRIPTION FACTOR DLX5; TRANSCRIPTION FACTOR RUNX2;

AGED; ARTICLE; BONE DENSITY; BONE MINERAL; CELL DIFFERENTIATION; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; FEMUR HEAD; FRACTURE NONUNION; HUMAN; HUMAN CELL; MESENCHYMAL STEM CELL; OSTEOPOROSIS; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; UPREGULATION;

EID: 84887077910     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2013.09.114     Document Type: Article

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