Anaemia management in patients with inflammatory bowel disease: Routine practice across nine European countries

European Journal of Gastroenterology and Hepatology

Volumn 25, Issue 12, 2013, Pages 1456-1463

  Stein, Jürgen ^a   Bager, Palle ^b   Befrits, Ragnar ^c   Gasche, Christoph ^d   Gudehus, Maja ^e   Lerebours, Eric ^f   Magro, Fernando ^g   Mearin, Fermin ^h   Mitchell, Daniell ^e   Oldenburg, Bas ⁱ   Danese, Silvio ^j  

^a Crohn Colitis Center Rhein Main   (Germany)

^b AARHUS UNIVERSITY HOSPITAL   (Denmark)

^c KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

^d MEDICAL UNIVERSITY OF VIENNA   (Austria)

^e Vifor (International) Inc   (Switzerland)

^f HÔPITAL CHARLES NICOLLE   (France)

^g UNIVERSITY OF PORTO   (Portugal)

^h CENTRO MÉDICO TEKNON   (Spain)

ⁱ UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

^j HUMANITAS CLINICAL AND RESEARCH CENTER   (Italy)

more..

Author keywords

intravenous iron; iron deficiency; iron replacement therapy; iron deficiency anaemia

Indexed keywords

ANTIANEMIC AGENT; FERRITIN; HEMOGLOBIN; IRON; TRANSFERRIN;

ADULT; ANEMIA; ARTICLE; CROSS-SECTIONAL STUDY; DIAGNOSTIC TEST; DISEASE SEVERITY; ENTERITIS; ERYTHROCYTE TRANSFUSION; EUROPE; FEMALE; FERRITIN BLOOD LEVEL; GASTROENTEROLOGIST; HEALTH SURVEY; HUMAN; IRON BLOOD LEVEL; IRON DEFICIENCY; IRON THERAPY; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; TRANSFERRIN BLOOD LEVEL;

ADULT; ANEMIA, IRON-DEFICIENCY; BIOLOGICAL MARKERS; CROSS-SECTIONAL STUDIES; DRUG UTILIZATION; ERYTHROCYTE TRANSFUSION; EUROPE; FEMALE; FERRITINS; GUIDELINE ADHERENCE; HEMATINICS; HEMOGLOBINS; HUMANS; INFLAMMATORY BOWEL DISEASES; IRON; MALE; MIDDLE AGED; PRACTICE GUIDELINES AS TOPIC; PROFESSIONAL PRACTICE; TRANSFERRIN;

EID: 84887051883     PISSN: 0954691X     EISSN: 14735687     Source Type: Journal    
DOI: 10.1097/MEG.0b013e328365ca7f     Document Type: Article

References (25)

1. Gisbert JP, Gomollon F. Common misconceptions in the diagnosis and management of anemia in inflammatory bowel disease. Am J Gastroenterol 2008; 103:1299-1307.
2. Graff LA, Vincent N,Walker JR, Clara I, Carr R, Ediger J, et al. A populationbased study of fatigue and sleep difficulties in inflammatory bowel disease. Inflamm Bowel Dis 2011; 17:1882-1889.
3. Stein J, Hartmann F, Dignass AU. Diagnosis and management of iron deficiency anemia in patients with IBD. Nat Rev Gastroenterol Hepatol 2010; 7:599-610.
4. Gasche C, Berstad A, Befrits R, Beglinger C, Dignass A, Erichsen K, et al. Guidelines on the diagnosis and management of iron deficiency and anemia in inflammatory bowel diseases. Inflamm Bowel Dis 2007; 13:1545-1553.
5. Kulnigg S, Gasche C. Systematic review: managing anaemia in Crohn's disease. Aliment Pharmacol Ther 2006; 24:1507-1523.
6. Semrin G, Fishman DS, Bousvaros A, Zholudev A, Saunders AC, Correia CE, et al. Impaired intestinal iron absorption in Crohn's disease correlates with disease activity and markers of inflammation. Inflamm Bowel Dis 2006; 12:1101-1106.
7. Weiss G, Goodnough LT. Anemia of chronic disease. N Engl J Med 2005; 352:1011-1023.
8. Fillet G, Beguin Y, Baldelli L. Model of reticuloendothelial iron metabolism in humans: abnormal behavior in idiopathic hemochromatosis and in inflammation. Blood 1989; 74:844-851.
9. WHO. Iron deficiency anaemia assessment, prevention, and control. A guide for programme managers. Geneva, Switzerland: WHO 2001; Available at: http://www.who.int/nutrition/publications/en/ida-assessment-prevention-control. pdf. [Accessed 11 September 2013].
10. Van Assche G, Dignass A, Bokemeyer B, Danese S, Gionchetti P, Moser G, et al. Second European evidence-based consensus on the diagnosis and management of ulcerative colitis part 3: special situations. J Crohns Colitis 2013; 7:1-33.
11. Beguin Y. Prediction of response and other improvements on the limitations of recombinant human erythropoietin therapy in anemic cancer patients. Haematologica 2002; 87:1209-1221.
12. Alleyne M, Horne MK, Miller JL. Individualized treatment for iron-deficiency anemia in adults. Am J Med 2008; 121:943-948.
13. Lyseng-Williamson KA, Keating GM. Ferric carboxymaltose: a review of its use in iron-deficiency anaemia. Drugs 2009; 69:739-756.
14. De Silva AD, Tsironi E, Feakins RM, Rampton DS. Efficacy and tolerability of oral iron therapy in inflammatory bowel disease: a prospective, comparative trial. Aliment Pharmacol Ther 2005; 22:1097-1105.
15. Kulnigg S, Stoinov S, Simanenkov V, Dudar LV, Karnafel W, Garcia LC, et al. A novel intravenous iron formulation for treatment of anemia in inflammatory bowel disease: the ferric carboxymaltose (FERINJECT) randomized controlled trial. Am J Gastroenterol 2008; 103:1182-1192.
16. Lindgren S, Wikman O, Befrits R, Blom H, Eriksson A, Granno C, et al. Intravenous iron sucrose is superior to oral iron sulphate for correcting anaemia and restoring iron stores in IBD patients: a randomized, controlled, evaluator-blind, multicentre study. Scand J Gastroenterol 2009; 44:838-845.
17. Schroder O, Mickisch O, Seidler U, de Weerth A, Dignass AU, Herfarth H, et al. Intravenous iron sucrose versus oral iron supplementation for the treatment of iron deficiency anemia in patients with inflammatory bowel disease-a randomized, controlled, open-label, multicenter study. Am J Gastroenterol 2005; 100:2503-2509.
18. National Comprehensive Cancer Network Inc. NCCN practice guidelines in oncology; cancer and chemotherapy-induced anemia-v.1.2013. Fort Washington, PA, USA: National Comprehensive Cancer Network (NCCN);2013.
19. Wish JB. Assessing iron status: beyond serum ferritin and transferrin saturation. Clin J Am Soc Nephrol 2006; 1 (Suppl 1):S4-S8.
20. Mowat C, Cole A,Windsor A, Ahmad T, Arnott I, Driscoll R, et al. Guidelines for the management of inflammatory bowel disease in adults. Gut 2011; 60:571-607.
21. Vavricka SR, Schoepfer AM, Safroneeva E, Rogler G, Schwenkglenks M, Achermann R. A shift from oral to intravenous iron supplementation therapy is observed over time in a large swiss cohort of patients with inflammatory bowel disease. Inflamm Bowel Dis 2013; 19:840-846.
22. Osterborg A. Recombinant human erythropoietin (rHuEPO) therapy in patients with cancer-related anaemia: what have we learned? Med Oncol 1998; 15 (Suppl 1):S47-S49.
23. Spahn DR, Moch H, Hofmann A, Isbister JP. Patient blood management: the pragmatic solution for the problems with blood transfusions. Anesthesiology 2008; 109:951-953.
24. Vamvakas EC, Blajchman MA. Transfusion-related mortality: the ongoing risks of allogeneic blood transfusion and the available strategies for their prevention. Blood 2009; 113:3406-3417.
25. Evstatiev R, Marteau P, Iqbal T, Khalif IL, Stein J, Bokemeyer B, et al. FERGIcor, a randomized controlled trial on ferric carboxymaltose for iron deficiency anemia in inflammatory bowel disease. Gastroenterology 2011; 141:846-853.