Anti-tumor activity of a peptide combining patterns of insect alloferons and mammalian immunoglobulins in naïve and tumor antigen vaccinated mice

International Immunopharmacology

Volumn 17, Issue 4, 2013, Pages 1090-1093

  Chernysh, Sergey ^a   Kozuharova, Irina ^b  

^a ST PETERSBURG STATE UNIVERSITY   (Russian Federation)

^b INSTITUTE OF CYTOLOGY   (Russian Federation)

Author keywords

Alloferons; Allostatine; Cancer immunotherapy; Immunoglobulins; Mouse tumor transplantation model

Indexed keywords

ALLOFERON 1; ALLOSTATINE; ANTINEOPLASTIC AGENT; IMMUNOGLOBULIN; TUMOR ANTIGEN; TUMOR VACCINE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER CELL; CANCER IMMUNIZATION; CANCER IMMUNOTHERAPY; CONTROLLED STUDY; CYTOTOXICITY; DRUG EFFICACY; DRUG STRUCTURE; FEMALE; IMMUNE RESPONSE; MAMMAL; MOUSE; MURINE LEUKEMIA; NATURAL KILLER CELL; NONHUMAN; PRIORITY JOURNAL;

ALLOFERONS; ALLOSTATINE; CANCER IMMUNOTHERAPY; IMMUNOGLOBULINS; MOUSE TUMOR TRANSPLANTATION MODEL;

AMINO ACID SEQUENCE; ANIMALS; ANTIGENS, NEOPLASM; ANTINEOPLASTIC AGENTS; CANCER VACCINES; CELL LINE, TUMOR; FEMALE; HUMANS; IMMUNOGLOBULINS; IMMUNOTHERAPY; INSECTS; MICE; MICE, INBRED DBA; NEOPLASMS; PEPTIDES; SEQUENCE ALIGNMENT; TUMOR BURDEN;

EID: 84887034872     PISSN: 15675769     EISSN: 18781705     Source Type: Journal    
DOI: 10.1016/j.intimp.2013.10.014     Document Type: Article

References (16)

1. I. Mellman, G. Coukos, and Glenn Dranoff Cancer immunotherapy comes of age Nature 480 2011 480 489
2. S.I. Chernysh, S.I. Kim, G. Bekker, V.A. Pleskach, N.A. Filatova, and V.B. Anikin Antiviral and antitumor peptides from insects Proc Natl Acad Sci U S A 99 2002 12628 12632
3. F.I. Ershov, A.A. Kubanova, B.V. Pinegin, A.E. Shulzhenko, G.P. Bekker, and S.I. Chernysh Allokine-α effect on the course of chronic genital herpes relapses Mater Med 40 2003 103 111
4. N. Lee, S. Bae, H. Kim, J.M. Kong, H.-R. Kim, and B.J. Cho Inhibition of lytic reactivation of Kaposi's sarcoma-associated herpesvirus by alloferon Antivir Ther 16 2011 17 26
5. S. Bae, K. Oh, H. Kim, Y. Kim, H.-R. Kim, and Y. Hwang The effect of alloferon on the enhancement of NK cell cytotoxicity against cancer via the up-regulation of perforin/granzyme B secretion Immunobiology 218 2013 1026 1033
6. N.E. Lee, J.S. Kang, J.E. Kim, D.A. Jung, S.K. Lee, and S. Bae Antiviral effect of Alloferon on Kaposi's sarcoma-associated herpesvirus FASEB J 22 2008 859
7. M. Kuczer, K. Dziubasik, A. Midak-Siewirska, R. Zahorska, M. Luczak, and D. Konopinska Studies of insect peptides alloferon, Any-GS and their analogues. Synthesis and antiherpes activity J Pept Sci 16 2010 186 189
8. M. Kuczer, A. Midak-Siewirska, R. Zahorska, M. Luczak, and D. Konopinska Further studies on the antiviral activity of alloferon and its analogues J Pept Sci 17 2011 715 719
9. M.-J. Ryu, V. Anikin, S.-H. Hong, H. Jeon, Y.G. Yu, and M.-H. Yu Activation of NF-kB by alloferon through down-regulation of antioxidant proteins and IkBα Mol Cell Biochem 313 2008 91 102
10. S.K. Lee, J.S. Kang, J.E. Kim, D.J. Jung, S. Bae, and N.E. Lee The anti-inflammatory effect of Alloferon on UVB irradiated human skin keratinocyte cell line, HaCaT via the regulation of pro-inflammatory cytokine production FASEB J 22 2008 1072
11. S. Chernysh, I. Kozuharova, and I. Artsibasheva Anti-tumor activity of immunomodulatory peptide alloferon-1 in mouse tumor transplantation model Int Immunopharmacol 12 2012 312 314
12. N.R. Safronnikova, S.I. Chernysh, and N.B. Serebranaya Modern methods of papilloma virus infection therapy N.R. Safronnikova, Preventive oncogynecology 2008 Costa St. Petersburg 142 159
13. S.I. Chernysh, N.A. Filatova, and N.S. Chernysh Cytotoxic activity of blow fly Calliphora vicina hemocytes J Insect Physiol 50 2004 777 781
14. M.V. Sidorova, A.S. Molokoedov, E.V. Kudrjavtseva, M.I. Baldin, D.A. Frid, and M.V. Ovchinnikov Synthesis of immunomodulatory peptide alloferon, active substance of antiviral preparation allokine-alpha Bioorg Chem 32 2006 151 160
15. S. Izumi, T. Ogawa, M. Michiyo, K. Fujie, M. Okuhara, and M. Kohsaka Antitumor effect of Nocardia rubra cell wall skeleton on syngeneically transplanted P388 tumors Cancer Res 51 1991 4038 4044
16. J.A. Berzofsky Improving immunotherapy: revisiting the immunologist's little secret Sci Transl Med 120 2012 1 3