Versatile immunomagnetic nanocarrier platform for capturing cancer cells

ACS Nano

Volumn 7, Issue 10, 2013, Pages 8816-8823

  Wu, Chun Hsien ^a   Huang, Yu Yen ^a   Chen, Peng ^a   Hoshino, Kazunori ^a   Liu, Huaying ^b   Frenkel, Eugene P ^b   Zhang, John X J ^a   Sokolov, Konstantin V ^a,c  

^a The University of Texas at Austin   (United States)

^b UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^c UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

Author keywords

circulating tumor cells; gold shell magnetic core nanoparticles; immunomagnetic assay; microfluidic chip

Indexed keywords

CIRCULATING TUMOR CELLS; EPITHELIAL CELL ADHESION MOLECULES; EPITHELIAL TO MESENCHYMAL TRANSITIONS; GOLD SHELL; IMMUNOFLUORESCENCE STAINING; IMMUNOMAGNETIC ASSAYS; MICROFLUIDIC CHIP; QUANTITATIVE ASSESSMENTS;

ANTIBODIES; ASSAYS; BIOMARKERS; BLOOD; DISEASES; ENZYME INHIBITION; FLUIDIC DEVICES;

CELLS;

NANOMATERIAL; TUMOR MARKER;

ARTICLE; HUMAN; IMMUNOMAGNETIC SEPARATION; METABOLISM; NEOPLASM; PATHOLOGY; TRANSMISSION ELECTRON MICROSCOPY;

HUMANS; IMMUNOMAGNETIC SEPARATION; MICROSCOPY, ELECTRON, TRANSMISSION; NANOSTRUCTURES; NEOPLASMS; TUMOR MARKERS, BIOLOGICAL;

EID: 84887005212     PISSN: 19360851     EISSN: 1936086X     Source Type: Journal    
DOI: 10.1021/nn403281e     Document Type: Article

References (36)

1. Meng, S.; Tripathy, D.; Shete, S.; Ashfaq, R.; Saboorian, H.; Haley, B.; Frenkel, E.; Euhus, D.; Leitch, M.; Osborne, C. et al. uPAR and HER-2 Gene Status in Individual Breast Cancer Cells from Blood and Tissues Proc. Natl. Acad. Sci. U.S.A. 2006, 103, 17361-17365
2. Zhang, L.; Farrell, J. J.; Zhou, H.; Elashoff, D.; Akin, D.; Park, N. H.; Chia, D.; Wong, D. T. Salivary Transcriptomic Biomarkers for Detection of Resectable Pancreatic Cancer Gastroenterology 2010, 138, 949-957.e7
3. Laxman, B.; Morris, D. S.; Yu, J.; Siddiqui, J.; Cao, J.; Mehra, R.; Lonigro, R. J.; Tsodikov, A.; Wei, J. T.; Tomlins, S. A. et al. A First-Generation Multiplex Biomarker Analysis of Urine for the Early Detection of Prostate Cancer Cancer Res. 2008, 68, 645-649
4. Cristofanilli, M.; Budd, G. T.; Ellis, M. J.; Stopeck, A.; Matera, J.; Miller, M. C.; Reuben, J. M.; Doyle, G. V.; Allard, W. J.; Terstappen, L. W. et al. Circulating Tumor Cells, Disease Progression, and Survival in Metastatic Breast Cancer N. Engl. J. Med. 2004, 351, 781-791
5. Cristofanilli, M.; Hayes, D. F.; Budd, G. T.; Ellis, M. J.; Stopeck, A.; Reuben, J. M.; Doyle, G. V.; Matera, J.; Allard, W. J.; Miller, M. C. et al. Circulating Tumor Cells: A Novel Prognostic Factor for Newly Diagnosed Metastatic Breast Cancer J. Clin. Oncol. 2005, 23, 1420-1430
6. Coumans, F. A.; Doggen, C. J.; Attard, G.; de Bono, J. S.; Terstappen, L. W. All Circulating EpCAM+CK+CD45 Objects Predict Overall Survival in Castration-Resistant Prostate Cancer Ann. Oncol. 2010, 21, 1851-1857
7. Riethdorf, S.; Fritsche, H.; Muller, V.; Rau, T.; Schindlbeck, C.; Rack, B.; Janni, W.; Coith, C.; Beck, K.; Jänicke, F. et al. Detection of Circulating Tumor Cells in Peripheral Blood of Patients with Metastatic Breast Cancer: A Validation Study of the Cellsearch System Clin. Cancer Res. 2007, 13, 920-928
8. Hoshino, K.; Huang, Y. Y.; Lane, N.; Huebschman, M.; Uhr, J. W.; Frenkel, E. P.; Zhang, X. Microchip-Based Immunomagnetic Detection of Circulating Tumor Cells Lab Chip 2011, 11, 3449-3457
9. Nagrath, S.; Sequist, L. V.; Maheswaran, S.; Bell, D. W.; Irimia, D.; Ulkus, L.; Smith, M. R.; Kwak, E. L.; Digumarthy, S.; Muzikansky, A. et al. Isolation of Rare Circulating Tumour Cells in Cancer Patients by Microchip Technology Nature 2007, 450, 1235-1239
10. Aktas, B.; Tewes, M.; Fehm, T.; Hauch, S.; Kimmig, R.; Kasimir-Bauer, S. Stem Cell and Epithelial-Mesenchymal Transition Markers Are Frequently Overexpressed in Circulating Tumor Cells of Metastatic Breast Cancer Patients Breast Cancer Res. 2009, 11, R46
11. Sieuwerts, A. M.; Kraan, J.; Bolt, J.; van der Spoel, P.; Elstrodt, F.; Schutte, M.; Martens, J. W.; Gratama, J. W.; Sleijfer, S.; Foekens, J. A. Anti-epithelial Cell Adhesion Molecule Antibodies and the Detection of Circulating Normal-like Breast Tumor Cells J. Natl. Cancer Inst. 2009, 101, 61-66
12. Mostert, B.; Kraan, J.; Bolt-de Vries, J.; van der Spoel, P.; Sieuwerts, A. M.; Schutte, M.; Timmermans, A. M.; Foekens, R.; Martens, J. W.; Gratama, J. W. et al. Detection of Circulating Tumor Cells in Breast Cancer May Improve through Enrichment with Anti-CD146 Breast Cancer Res. Treat. 2011, 127, 33-41
13. Lee, H.; Lee, E.; Kim, D. K.; Jang, N. K.; Jeong, Y. Y.; Jon, S. Antibiofouling Polymer-Coated Superparamagnetic Iron Oxide Nanoparticles as Potential Magnetic Resonance Contrast Agents for In Vivo Cancer Imaging J. Am. Chem. Soc. 2006, 128, 7383-7389
14. Farokhzad, O. C.; Langer, R. Impact of Nanotechnology on Drug Delivery ACS Nano 2009, 3, 16-20
15. Barcikowski, S.; Compagnini, G. Advanced Nanoparticle Generation and Excitation by Lasers in Liquids Phys. Chem. Chem. Phys. 2013, 15, 3022-3026
16. Bigall, N. C.; Parak, W. J.; Dorfs, D. Fluorescent, Magnetic and Plasmonic-Hybrid Multifunctional Colloidal Nano Objects Nano Today 2012, 7, 282-296
17. Larson, T. A.; Bankson, J.; Aaron, J.; Sokolov, K. Hybrid Plasmonic Magnetic Nanoparticles as Molecular Specific Agents for MRI/Optical Imaging and Photothermal Therapy of Cancer Cells Nanotechnology 2007, 18, 325101
18. Song, H.-M.; Wei, Q.; Ong, Q. K.; Wei, A. Plasmon-Resonant Nanoparticles and Nanostars with Magnetic Cores: Synthesis and Magnetomotive Imaging ACS Nano 2010, 4, 5163-5173
19. Wei, Q.; Song, H.-M.; Leonov, A. P.; Hale, J. A.; Oh, D.; Ong, Q. K.; Ritchie, K.; Wei, A. Gyromagnetic Imaging: Dynamic Optical Contrast Using Gold Nanostars with Magnetic Cores J. Am. Chem. Soc. 2009, 131, 9728-9734
20. Kumar, S.; Aaron, J.; Sokolov, K. V. Directional Conjugation of Antibodies to Nanoparticles for Synthesis of Multiplexed Optical Contrast Agents with Both Delivery and Targeting Moieties Nat. Protoc. 2008, 3, 314-320
21. Kumar, S.; Harrison, N.; Richards-Kortum, R.; Sokolov, K. Plasmonic Nanosensors for Imaging Intracellular Biomarkers in Live Cells Nano Lett. 2007, 7, 1338-1343
22. Huang, K.; Ma, H.; Liu, J.; Huo, S.; Kumar, A.; Wei, T.; Zhang, X.; Jin, S.; Gan, Y.; Wang, P. C. et al. Size-Dependent Localization and Penetration of Ultrasmall Gold Nanoparticles in Cancer Cells, Multicellular Spheroids, and Tumors in Vivo ACS Nano 2012, 6, 4483-4493
23. Anker, J. N.; Hall, W. P.; Lyandres, O.; Shah, N. C.; Zhao, J.; Van Duyne, R. P. Biosensing with Plasmonic Nanosensors Nat. Mater. 2008, 7, 442-453
24. 4@Au Nanoparticles J. Phys. Chem. B 2005, 109, 21593-21601
25. Wang, Y.; Wong, J. F.; Teng, X.; Lin, X. Z.; Yang, H. "Pulling" Nanoparticles into Water: Phase Transfer of Oleic Acid Stabilized Monodisperse Nanoparticles into Aqueous Solutions of α-Cyclodextrin Nano Lett. 2003, 3, 1555-1559
26. Devriese, L. A.; Voest, E. E.; Beijnen, J. H.; Schellens, J. H. Circulating Tumor Cells as Pharmacodynamic Biomarker in Early Clinical Oncological Trials Cancer Treat. Rev. 2011, 37, 579-589
27. Hermanson, G. T. Bioconjugate Techniques, 2 nd ed.; Academic Press: Waltham, MA, 2008; pp 761-764.
28. Bobbitt, J. M. Periodate Oxidation of Carbohydrates Adv. Carbohydr. Chem. 1956, 11, 1-41
29. Rae, J. M.; Scheys, J. O.; Clark, K. M.; Chadwick, R. B.; Kiefer, M. C.; Lippman, M. E. EGFR and EGFRvIII Expression in Primary Breast Cancer and Cell Lines Breast Cancer Res. Treat. 2004, 87, 87-95
30. Aaron, J.; Nitin, N.; Travis, K.; Kumar, S.; Collier, T.; Park, S. Y.; Jose-Yacaman, M.; Coghlan, L.; Follen, M.; Richards-Kortum, R. et al. Plasmon Resonance Coupling of Metal Nanoparticles for Molecular Imaging of Carcinogenesis in Vivo J. Biomed. Opt. 2007, 12, 034007
31. Aaron, J.; Travis, K.; Harrison, N.; Sokolov, K. Dynamic Imaging of Molecular Assemblies in Live Cells Based on Nanoparticle Plasmon Resonance Coupling Nano Lett. 2009, 9, 3612-3618
32. Wang, J.; Boriskina, S. V.; Wang, H.; Reinhard, B. M. Illuminating Epidermal Growth Factor Receptor Densities on Filopodia through Plasmon Coupling ACS Nano 2011, 5, 6619-6628
33. Wang, J.; Yu, X.; Boriskina, S. V.; Reinhard, B. M. Quantification of Differential ErbB1 and ErbB2 Cell Surface Expression and Spatial Nanoclustering through Plasmon Coupling Nano Lett. 2012, 12, 3231-3237
34. Crow, M. J.; Seekell, K.; Ostrander, J. H.; Wax, A. Monitoring of Receptor Dimerization Using Plasmonic Coupling of Gold Nanoparticles ACS Nano 2011, 5, 8532-8540
35. Hoshino, K.; Chen, P.; Huang, Y.-Y.; Zhang, X. Computational Analysis of Microfluidic Immunomagnetic Rare Cell Separation from a Particulate Blood Flow Anal. Chem. 2012, 84, 4292-4299
36. Punnoose, E. A.; Atwal, S. K.; Spoerke, J. M.; Savage, H.; Pandita, A.; Yeh, R. F.; Pirzkall, A.; Fine, B. M.; Amler, L. C.; Chen, D. S. et al. Molecular Biomarker Analyses Using Circulating Tumor Cells PLoS One 2010, 5, e12517