Reduced expression of TRIF in chronic HBV infected Iranian patients

Clinics and Research in Hepatology and Gastroenterology

Volumn 37, Issue 5, 2013, Pages 491-495

  Ayoobi, Fatemeh ^a   Hassanshahi, Gholamhossein ^a   Zainodini, Nahid ^a   Khorramdelazad, Hossein ^a   Arababadi, Mohammad Kazemi ^a   Kennedy, Derek ^b  

^a RAFSANJAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^b GRIFFITH UNIVERSITY   (Australia)

Author keywords

HBV; IRAK1; IRF3; MYD88; NF B; PAMP; PBMC; TLR; TRAF6; TRIF

Indexed keywords

BETA ACTIN; MESSENGER RNA; TOLL LIKE RECEPTOR 3; TOLL LIKE RECEPTOR 4; TOLL LIKE RECEPTOR ADAPTOR MOLECULE 1;

ARTICLE; CHRONIC HEPATITIS; CONTROLLED STUDY; GENE EXPRESSION; HEPATITIS B; HEPATITIS B VIRUS; HOUSEKEEPING GENE; HUMAN; HUMAN CELL; MAJOR CLINICAL STUDY; PERIPHERAL BLOOD MONONUCLEAR CELL; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA ISOLATION;

HBV; HEPATITIS B VIRUS; INTERFERON REGULATORY TRANSCRIPTION FACTOR 3; INTERLEUKIN-1 RECEPTOR ASSOCIATED KINASE-1; IRAK1; IRF3; MYD88; MYELOID DIFFERENTIATION PRIMARY RESPONSE; NF-ΚB; NUCLEAR FACTOR KAPPA-LIGHT-CHAIN-ENHANCER OF ACTIVATED B CELLS; PAMP; PATHOGEN ASSOCIATED MOLECULAR PATTERNS; PBMC; PERIPHERAL BLOOD MONONUCLEAR CELL; TIR-DOMAIN-CONTAINING ADAPTER-INDUCING INTERFERON-Β; TLR; TNF RECEPTOR ASSOCIATED FACTOR; TOLL LIKE RECEPTOR; TRAF6; TRIF;

ADAPTOR PROTEINS, VESICULAR TRANSPORT; ALANINE TRANSAMINASE; ALKALINE PHOSPHATASE; ASPARTATE AMINOTRANSFERASES; BILIRUBIN; CASE-CONTROL STUDIES; DNA, VIRAL; GENOTYPE; HEPATITIS B SURFACE ANTIGENS; HEPATITIS B VIRUS; HEPATITIS B, CHRONIC; HUMANS; IRAN; LEUKOCYTES, MONONUCLEAR; REAL-TIME POLYMERASE CHAIN REACTION; RNA, MESSENGER;

EID: 84886951160     PISSN: 22107401     EISSN: 2210741X     Source Type: Journal    
DOI: 10.1016/j.clinre.2012.11.005     Document Type: Article

References (26)

1. Assar A., Arababadi M.K., Mohit M., Ahmadabadi B.N., Pumpens P., Khorramdelazad H., et al. T helper and B cell escape mutations within the HBc gene in patients with asymptomatic HBV infection: a study from the South-Eastern region of Iran. Clin Lab 2012, 58:53-60.
2. Chan H.L., Jia J. Chronic hepatitis B in Asia-new insights from the past decade. J Gastroenterol Hepatol 2011, 26(Suppl 1):131-137.
3. Mendy M.E., Welzel T., Lesi O.A., Hainaut P., Hall A.J., Kuniholm M.H., et al. Hepatitis B viral load and risk for liver cirrhosis and hepatocellular carcinoma in The Gambia West Africa. J Viral Hepat 2009, 27:27.
4. Michielsen P., Ho E. Viral hepatitis B and hepatocellular carcinoma. Acta Gastroenterol Belg 2011, 74(1):4-8.
5. Ahmadabadi B.N., Hassanshahi G., Arababadi M.K., Leanza C., Kennedy D. The IL-10 promoter polymorphism at position -592 is correlated with susceptibility to occult HBV infection. Inflammation 2012, 35(3):818-821.
6. Arababadi M.K., Pourfathollah A.A., Jafarzadeh A., Hassanshahi G., Rezvani M.E. Association of exon 9 but not intron 8 VDR polymorphisms with occult HBV infection in south-eastern Iranian patients. J Gastroenterol Hepatol 2009, 25(1):90-93.
7. Feitelson M.A. Parallel epigenetic and genetic changes in the pathogenesis of hepatitis virus-associated hepatocellular carcinoma. Cancer Lett 2006, 239(1):10-20.
8. Arababadi M.K., Ahmadabadi B.N., Kennedy D. Current information on the immunological status of occult hepatitis B infection. Transfusion 2012, 52(8):1819-1826.
9. Nguyen-Pham T.N., Lim M.S., Nguyen T.A., Lee Y.K., Jin C.J., Lee H.J., et al. Type I and II interferons enhance dendritic cell maturation and migration capacity by regulating CD38 and CD74 that have synergistic effects with TLR agonists. Cell Mol Immunol 2011, 8(4):341-347.
10. Bae Y.S., Lee J.H., Choi S.H., Kim S., Almazan F., Witztum J.L., et al. Macrophages generate reactive oxygen species in response to minimally oxidized low-density lipoprotein: toll-like receptor 4- and spleen tyrosine kinase-dependent activation of NADPH oxidase 2. Circ Res 2009, 104(2):210-218. 21p following 8.
11. Hirayama T., Tamaki Y., Takakubo Y., Iwazaki K., Sasaki K., Ogino T., et al. Toll-like receptors and their adaptors are regulated in macrophages after phagocytosis of lipopolysaccharide-coated titanium particles. J Orthop Res 2011, 29(7):984-992.
12. Imani Fooladi A.A., Mousavi S.F., Seghatoleslami S., Yazdani S., Nourani M.R. Toll-like receptors: role of inflammation and commensal bacteria. Inflamm Allergy Drug Targets 2011, 10(3):198-207.
13. Jia N., Xie Q., Lin L., Gui H., Wang H., Jiang S., et al. Common variants of the TLR9 gene influence the clinical course of HBV infection. Mol Med Report 2009, 2(2):277-281.
14. Takeda K., Akira S. Toll-like receptors. Curr Protoc Immunol 2007, 2. Chapter 14(14): Unit 14 2.
15. Tili E., Michaille J.J., Cimino A., Costinean S., Dumitru C.D., Adair B., et al. Modulation of miR-155 and miR-125b levels following lipopolysaccharide/TNF-alpha stimulation and their possible roles in regulating the response to endotoxin shock. J Immunol 2007, 179(8):5082-5089.
16. Eftekhari Y., Arababadi M.K., Hakimi H., Zarandi E.R. Common HBV genotype in southeastern Iranian patients. Arch Iran Med 2010, 13(2):147-149.
17. Cheng X.Y., Zhang L.L. The significance of CD14 and TLR4 expressions in severe hepatitis B induced by endotoxin. Zhonghua Gan Zang Bing Za Zhi 2007, 18(6):428-432.
18. Khvalevsky E., Rivkin L., Rachmilewitz J., Galun E., Giladi H. TLR3 signaling in a hepatoma cell line is skewed towards apoptosis. J Cell Biochem 2007, 100(5):1301-1312.
19. Li N., Li Q., Qian Z., Zhang Y., Chen M., Shi G. Impaired TLR3/IFN-beta signaling in monocyte-derived dendritic cells from patients with acute-on-chronic hepatitis B liver failure: relevance to the severity of liver damage. Biochem Biophys Res Commun 2009, 390(3):630-635.
20. An B.Y., Xie Q., Lin L.Y., Shen H.C., Jia N.N., Wang H., et al. Expression of Toll-like receptor 3 on peripheral blood dendritic cells in HBeAg positive patients with chronic hepatitis B. Zhonghua Gan Zang Bing Za Zhi 2007, 15(10):729-733.
21. Chen Z., Cheng Y., Xu Y., Liao J., Zhang X., Hu Y., et al. Expression profiles and function of Toll-like receptors 2 and 4 in peripheral blood mononuclear cells of chronic hepatitis B patients. Clin Immunol 2008, 128(3):400-408.
22. Guo H., Jiang D., Ma D., Chang J., Dougherty A.M., Cuconati A., et al. Activation of pattern recognition receptor-mediated innate immunity inhibits the replication of hepatitis B virus in human hepatocyte-derived cells. J Virol 2009, 83(2):847-858.
23. Tjwa E.T., van Oord G.W., Biesta P.J., Boonstra A., Janssen H.L., Woltman A.M. Restoration of TLR3-activated myeloid dendritic cell activity leads to improved natural killer cell function in chronic hepatitis B. J Virol 2011, 2012:8.
24. Wang K., Liu H., He Y., Chen T., Yang Y., Niu Y., et al. Correlation of TLR1-10 expression in peripheral blood mononuclear cells with chronic hepatitis B and chronic hepatitis B-related liver failure. Hum Immunol 2010, 71(10):950-956.
25. Wei X.Q., Guo Y.W., Liu J.J., Wen Z.F., Yang S.J., Yao J.L. The significance of Toll-like receptor 4 (TLR4) expression in patients with chronic hepatitis B. Clin Invest Med 2008, 31(3):E123-E130.
26. Yu S., Chen J., Wu M., Chen H., Kato N., Yuan Z. Hepatitis B virus polymerase inhibits RIG-I- and Toll-like receptor 3-mediated beta interferon induction in human hepatocytes through interference with interferon regulatory factor 3 activation and dampening of the interaction between TBK1/IKKepsilon and DDX3. J Gen Virol 2011, 91(Pt 8):2080-2090.