Comparison of AAV/IL-7 autocrine (T cell) versus paracrine (DC) gene delivery for enhancing CTL stimulation and function

Cancer Immunology, Immunotherapy

Volumn 59, Issue 5, 2010, Pages 779-787

  You, Chang Xuan ^a,b   Liu, Yong ^a   Shi, Min ^a,b   Cao, Maohua ^a   Luo, Rong Cheng ^b   Hermonat, Paul L ^a  

^a UNIVERSITY OF ARKANSAS FOR MEDICAL SCIENCES   (United States)

^b SOUTHERN MEDICAL UNIVERSITY   (China)

Author keywords

Autocrine; Cytotoxic t lymphocytes dendritic cell; Interleukin 7; Paracrine gene delivery

Indexed keywords

CARCINOEMBRYONIC ANTIGEN; CD69 ANTIGEN; CYTOKINE; INTERLEUKIN 2; INTERLEUKIN 7; PARVOVIRUS VECTOR;

ANTIGEN SPECIFICITY; ARTICLE; AUTOCRINE EFFECT; CANCER CELL CULTURE; CD4 CD8 RATIO; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CELL KILLING; CELL STRAIN HEK293; CONTROLLED STUDY; CYTOTOXIC T LYMPHOCYTE; DENDRITIC CELL; DRUG MECHANISM; GENE EXPRESSION REGULATION; GENETIC TRANSDUCTION; HUMAN; HUMAN CELL; IMMUNOGENETICS; LYMPHOCYTE ACTIVATION; LYMPHOCYTE FUNCTION; LYMPHOCYTE PROLIFERATION; LYMPHOCYTE SUBPOPULATION; PARACRINE SIGNALING; PRIORITY JOURNAL; PROCESS OPTIMIZATION; REGULATORY T LYMPHOCYTE; TH1 CELL; VIRAL GENE DELIVERY SYSTEM; ADENO ASSOCIATED VIRUS; CELL SEPARATION; COMPARATIVE STUDY; FLOW CYTOMETRY; GENE THERAPY; GENE VECTOR; GENETICS; IMMUNOLOGY; IMMUNOTHERAPY; METHODOLOGY; T LYMPHOCYTE; T LYMPHOCYTE SUBPOPULATION;

CARCINOEMBRYONIC ANTIGEN; CELL SEPARATION; DENDRITIC CELLS; DEPENDOVIRUS; FLOW CYTOMETRY; GENE THERAPY; GENETIC VECTORS; HUMANS; IMMUNOTHERAPY; INTERLEUKIN-2; INTERLEUKIN-7; T-LYMPHOCYTE SUBSETS; T-LYMPHOCYTES; T-LYMPHOCYTES, CYTOTOXIC; TRANSDUCTION, GENETIC;

EID: 77950502893     PISSN: 03407004     EISSN: 14320851     Source Type: Journal    
DOI: 10.1007/s00262-009-0798-0     Document Type: Article

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