Toll-like receptor system and endometriosis

Journal of Obstetrics and Gynaecology Research

Volumn 39, Issue 8, 2013, Pages 1281-1292

  Khan, Khaleque Newaz ^a   Kitajima, Michio ^a   Fujishita, Akira ^b   Nakashima, Masahiro ^a   Masuzaki, Hideaki ^a  

^a NAGASAKI UNIVERSITY   (Japan)

^b Nagasakiken Saiseikai Hospital   (Japan)

Author keywords

bacterial endotoxin; endometriosis; endometrium; infertility; innate immunity; Toll like receptors

Indexed keywords

CHAPERONIN 60; CYTOKINE; ENDOTOXIN; FIBRINOGEN; FIBRONECTIN; FLAGELLIN; HEAT SHOCK PROTEIN 70; HEPARAN SULFATE; HYALURONIC ACID; IMIDAZOQUINOLINE DERIVATIVE; LIPOPEPTIDE; LIPOPOLYSACCHARIDE; LIPOTEICHOIC ACID; MYELOID DIFFERENTIATION FACTOR 88; PACLITAXEL; PEPTIDOGLYCAN; PORIN; STEROID HORMONE; TOLL LIKE RECEPTOR; TOLL LIKE RECEPTOR 1; TOLL LIKE RECEPTOR 2; TOLL LIKE RECEPTOR 3; TOLL LIKE RECEPTOR 4; TOLL LIKE RECEPTOR 5; TOLL LIKE RECEPTOR 6; TOLL LIKE RECEPTOR 7; TOLL LIKE RECEPTOR 8; TOLL LIKE RECEPTOR 9; UNINDEXED DRUG; ZYMOSAN;

ARTICLE; BACTERIAL STRAIN; CELL MEMBRANE; CYTOKINE RELEASE; CYTOPLASM; DISEASE ASSOCIATION; ENDOMETRIOSIS; ENDOMETRIUM; ENDOMETRIUM CELL; ESCHERICHIA COLI; FEMALE INFERTILITY; FERTILIZATION IN VITRO; GRAM NEGATIVE AEROBIC RODS AND COCCI; GRAM POSITIVE BACTERIUM; GROWTH REGULATION; HISTOPATHOLOGY; HUMAN; IMMUNOCOMPETENT CELL; INFLAMMATION; INNATE IMMUNITY; INTRACELLULAR SIGNALING; MACROPHAGE; MOLECULAR RECOGNITION; NONHUMAN; OVARY; OXIDATIVE STRESS; PHAGOCYTOSIS; PROTEIN ANALYSIS; PROTEIN FUNCTION; QUALITY OF LIFE; RISK FACTOR; SIGNAL TRANSDUCTION; ANIMAL; BIOLOGICAL MODEL; DENDRITIC CELL; FEMALE; IMMUNOLOGY; INFERTILITY; METABOLISM; REVIEW;

BACTERIAL ENDOTOXIN; ENDOMETRIOSIS; ENDOMETRIUM; INFERTILITY; INNATE IMMUNITY; TOLL-LIKE RECEPTORS;

ANIMALS; DENDRITIC CELLS; ENDOMETRIOSIS; ENDOMETRIUM; FEMALE; HUMANS; IMMUNITY, INNATE; MACROPHAGES; MODELS, BIOLOGICAL; TOLL-LIKE RECEPTORS;

EID: 84886907542     PISSN: 13418076     EISSN: 14470756     Source Type: Journal    
DOI: 10.1111/jog.12117     Document Type: Article

References (70)

1. Janeway CAJ,. Approaching the Asymptote? Evolution and revolution in immunology. Cold Spring Harb Symp Quant Biol 1989; 54: 1-13.
2. Janeway CAJ, Medzhitov R,. Innate immune recognition. Annu Rev Immunol 2002; 20: 197-216.
3. Reichhart JM,. TLR5 takes aim at bacterial propeller. Nat Immunol 2003; 4: 1159-1160.
4. Takeda K, Akira S,. Toll-like receptors in innate immunity. Int Immunol 2005; 17: 1-14.
5. Wira CR, Fahey JV, Sentman CL, Pioli PA, Shen L,. Innate and adaptive immunity in female genital tract: Cellular responses and interactions. Immunol Rev 2005; 206: 306-335.
6. Burney RO, Giudice LC,. Pathogenesis and pathophysiology of endometriosis. Fertil Steril 2012; 98: 511-519.
7. Attar E, Bulun SE,. Aromatase and other steroidogenic genes in endometriosis: Translational aspects. Hum Reprod Update 2006; 12: 49-56.
8. Khan KN, Kitajima M, Hiraki H, et al. Immunopathogenesis of pelvic endometriosis: Role of hepatocyte growth factor, macrophages and ovarian steroids. Am J Reprod Immunol (review) 2008; 60: 383-404.
9. Khan KN, Kitajima M, Hiraki H, et al. Toll-like receptors in innate immunity: Role of bacterial endotoxin and toll-like receptor 4 (TLR4) in endometrium and endometriosis. Gynecol Obstet Invest (review) 2009; 68: 40-52.
10. Khan KN, Kitajima M, Hiraki K, et al. Escherichia coli contamination of menstrual blood and effect of bacterial endotoxin on endometriosis. Fertil Steril 2010; 94 (7): 2860-2863.
11. Fazeli A, Bruce C, Anumba DO,. Characterization of Toll-like receptors in the female reproductive tract in humans. Hum Reprod 2005; 20: 1372-1378.
12. Aflatoonian R, Tuckerman E, Elliot SL, et al. Menstrual cycle-dependent changes of toll-like receptors in endometrium. Hum Reprod 2007; 22: 586-593.
13. Hirata T, Osuga Y, Hamasaki K, et al. Expression of Toll-like receptor 2, 3, 4, and 9 in the human endometrium during the menstrual cycle. J Reprod Immunol 2007; 74: 53-60.
14. Rock FL, Hardiman G, Timans JC, Kastelein RA, Bazan JF,. A family of human receptors structurally related to Drosophila Toll. Proc Natl Acad Sci U S A 1998; 95: 588.
15. Zhang D, Zhang G, Hayden MS, et al. A toll-like receptor that prevents infection by uropathogenic bacteria. Science 2004; 303: 1522-1526.
16. Poltorak A, et al. Defective LPS signaling in C3H/HeJ and C57BL/10ScCr mice: Mutation in Tlr4 gene. Science 1998; 282: 2085-2088.
17. Takeuchi O, Hoshino K, Kawai T, et al. Differential roles of TLR2 and TLR4 in recognition of gram-negative and gram-positive bacterial cell wall components. Immunity 1999; 11: 443-451.
18. Nasu K, Itoh H, Yugae A, Nishida M, Narahara H,. Human oviductal epithelial cells express Toll-like receptor 3 and respond to double-stranded RNA: Fallopian tube-specific mucosal immunity against viral infection. Hum Reprod 2007; 22: 356-361.
19. Kiechl S, Lorenz E, Reindl M, et al. Toll-like receptor 4 polymorphisms and atherogenesis. N Engl J Med 2002; 347: 185-192.
20. Akira S, Takeda K,. Toll-like receptor signaling. Nat Rev Immunol 2004; 4: 499-511.
21. Hoshino K, Takeuchi O, Kawai T, et al. Cutting edge: Toll-like receptor 4 (TLR4)-deficient mice are hyporesponsive to lipopolysaccharide: evidence for TLR4 as the LPS gene product. J Immunol 1999; 162: 3749-3752.
22. Wallin RPA, Lundqvist A, More SH, von Bonin A, Kiessling R, Ljunggren H-G,. Heat-shock proteins as activators of the innate immune system. Trends Immunol 2002; 23: 130-135.
23. McCoy CE, O'Neill LAJ,. The role of toll-like receptors in macrophages. Front Biosci 2008; 13: 62-70.
24. Parker LC, Prince LR, Sabroe I,. Translational mini-review series on toll-like receptors: Networks regulated by toll-like receptors mediate innate and adaptive immunity. Clin Exp Immunol 2007; 147: 199-207.
25. Akira S,. Mammalian Toll-like receptors. Curr Opin Immunol 2003; 15: 5-11.
26. Check W,. Innate immunity depends on Toll-like receptors. ASM News 2004; 70: 317-322.
27. Abrahams VM, Schaefer TM, Fahey JV, et al. Expression and Secretion of antiviral factors by trophoblast cells following stimulation by the TLR-3 agonist, Poly (I:C). Hum Reprod 2006; 21: 2432-2439.
28. Sheldon IM, Noakes DE, Rycroft AN, Pfeiffer DU, Dobson H,. Influence of uterine bacterial contamination after parturition on ovarian dominant follicle selection and follicle growth and function in cattle. Reproduction 2002; 123: 837-845.
29. Larsen S, Galask RP,. Vaginal microbial flora: Practical and theoretic relevance. Obstet Gynecol 1980; 55: 100S-113S.
30. Eriksson M, Measows SK, Basu S, Mselle TF, Wira CR, Sentman CL,. TLRs mediate IFN-γ production by human uterine NK cells in endometrium. J Immunol 2006; 176: 6219-6224.
31. Young SL, Lyddon TD, Jorgenson RL, Misfeldt ML,. Expression of Toll-like receptors in human endometrial epithelial cells and cell lines. Am J Reprod Immunol 2004; 52: 67-73.
32. Hirata T, Osuga Y, Hirota Y, et al. Evidence for the presence of Toll-like receptor 4 system in the human endometrium. J Clin Endocrinol Metab 2005; 90: 548-556.
33. Fazeli A, Bruce C, Anumba DO,. Characterization of Toll-like receptors in the female reproductive tract in humans. Hum Reprod 2005; 20: 1372-1378.
34. Khan KN, Masuzaki H, Fujishita A, Kitajima M, Sekine I, Ishimaru T,. Differential macrophage infiltration in early and advanced endometriosis and adjacent peritoneum. Fertil Steril 2004; 81: 652-661.
35. Khan KN, Kitajima M, Hiraki K, et al. Changes in tissue inflammation, angiogenesis and apoptosis in endometriosis, adenomyosis and uterine myoma after GnRH agonist therapy. Hum Reprod 2010; 25: 642-653.
36. Miura S, Khan KN, Kitajima M, et al. Differential infiltration of macrophages and prostaglandin production by different uterine leiomyomas. Hum Reprod 2006; 21 (10): 2545-2554.
37. Khan KN, Masuzaki H, Fujishita A, et al. Regulation of hepatocyte growth factor by basal and stimulated-macrophages in women with endometriosis. Hum Reprod 2005; 20: 49-60.
38. Khan KN, Kitajima M, Fujishita A, Sekine I, Ishimaru T, Masuzaki H,. Multifunctional role of hepatocyte growth factor (HGF) in the development of pelvic endometriosis. WES e-journal (review) 2008; July: 13-20.
39. Khan KN, Kitajima M, Imamura T, Hiraki K, Fujishita A, Sekine I, Ishimaru T, Masuzaki H,. Toll-like receptor 4 (TLR4)-mediated growth of endometriosis by human heat shock protein 70 (Hsp70). Hum Reprod 2008; 23: 2210-2219.
40. Iba Y, Harada T, Horie S, Deura I, Iwabe T, Terakawa N,. Lipopolysaccharide-promoted proliferation of endometriotic stromal cells via induction of tumor necrosis factor α and interleukin-8 expression. Fertil Steril 2004; 82 (Suppl 3): 1036-1042.
41. Alexander JW, Boyce ST, Babcock GF, et al. The Process of microbial translocation. Ann Surg 1990; 212: 496-511.
42. Khan KN, Kitajima M, Yamaguchi N, et al. Role of prostaglandin E2 in bacterial growth in women with endometriosis. Hum Reprod 2012; 27: 3417-3424.
43. Valore EV, Park CH, Quayle AJ, Wilee KR, McCray Jr. PB, Ganz T,. Human β-defensin-1: An antimicrobial peptide of urogenital tissues. J Clin Invest 1998; 101: 1633-1642.
44. Asea A, Krafft SK, Kurt-Jones EA, et al. HSP70 stimulates cytokine production through a CD14-dependent pathway, demonstrating its dual role as a chaperone and cytokine. Nat Med 2000; 6: 435-442.
45. Asea A, Rehli M, Kabingu E, et al. Novel signal transduction pathway utilized by extracellular HSP70: role of toll-like receptor (TLR) 2 and TLR4. J Biol Chem 2002; 277: 15028-15034.
46. Zugel U, Kaufmann SH,. Immune response against heat-shock proteins in infectious diseases. Immunobiology 1999; 201: 22-35.
47. Matzinger P,. An innate sense of danger. Semin Immunol 1998; 10: 399-415.
48. th World Congress on Endometriosis. 2011; p204.
49. Khan KN, Masuzaki H, Fujishita A, Kitajima M, Sekine I, Ishimaru T,. Higher activity by opaque endometriotic lesions than non-opaque lesions in women with endometriosis. Acta Obstet Gynecol Scand 2004; 83: 375-382.
50. Burney RO, Lathi RB,. Menstrual bleeding from an endometriotic bleeding. Fertil Steril 2009; 91: 1926-1927.
51. Kalmar B, Greensmith L,. Induction of heat shock proteins for protection against oxidative stress. Adv Drug Deliv Rev 2009; 61: 310-318.
52. Kajihara H, Yamada Y, Kanayama S, et al. New insights into the pathophysiology of endometriosis: From chronic inflammation to danger signals. Gynecol Endocrinol 2011; 27 (2): 73-79.
53. Beagley KW, Gockel CM,. Regulation of innate and adaptive immunity by the female sex hormones estradiol annd progesterone. FEMS Immunol Med Microbiol 2003; 38: 13-22.
54. Herath S, Fischer FD, Werling D, et al. Expression and Function of Toll-like receptor 4 in the endometrial cells of the uterus. Endocrinology 2006; 147: 562-570.
55. Khan KN, Masuzaki H, Fujishita A, et al. Estrogen and progesterone receptor expression in macrophages and regulation of hepatocyte growth factor by ovarian steroids in women with endometriosis. Hum Reprod 2005; 20: 2004-2013.
56. Khan KN, Masuzaki H, Fujishita A, et al. Interleukin-6 and tumor necrosis factor α-mediated expression of hepatocte growth factor by stromal cells and its involvement in the growth of endometriosis. Hum Reprod 2005; 20: 2715-2723.
57. th Proceedings of Acta Obstretica et Gynecologica Japonica. 2012; p813.
58. Cakmak H, Guzeloglu-Kayisli O, Kayisli UA, Arici A,. Immune-endocrine interactions in endometriosis. Front Biosci 2009; E1: 429-443.
59. D'Hooghe TM, Debrock S, Hill JA, Meuleman C,. Endometriosis and subfertility: Is the relationship resolved? Sem Reprod Med 2003; 21: 243-254.
60. Tomassetti C, Meuleman C, Pexsters A, et al. Endometriosis, recurrent miscarriage and implantation failure: Is there an immunological link? Reprod BioMed Online 2006; 13: 58-64.
61. Cakmak H, Taylor HS,. Implantation failure: Molecular mechanisms and clinical treatment. Hum Reprod Update 2011; 17: 242-253.
62. Agarwal A, Gupta S, Sharma R,. Oxidative stress and its implications in female infertility-a clinician's perspective (review article). Reprod BioMed Online 2005; 11: 641-650.
63. Gupta S, Agarwal A, Krajcir N, Alvarez JG,. Role of oxidative stress in endometriosis. Reprod BioMed Online 2006; 13: 126-134.
64. Adamson GD, Pasta DJ,. Surgical treatment of endometriosis-associated infertility: Meta-analysis compared with survival analysis. Am J Obstet Gynecol 1994; 171: 1488-1504.
65. Deb K, Chatturvedi MM, Jaiswal YK,. Gram-negative bacterial endotoxin-induced infertility: A bird eye view. Gynecol Obstet Invest 2004; 57: 224-232.
66. Kamiyama S, Teruya Y, Nohara M, Kanzawa K,. Impact of detection of bacterial endotoxin in menstrual effluent on the pregnancy rate in in vitro fertilization and embryo transfer. Fertil Steril 2004; 82: 788-792.
67. Fujita Y, Mihara T, Okazaki T, et al. Toll-like receptors (TLR) 2 and 4 on human sperm recognize bacterial endotoxins and mediate apoptosis. Hum Reprod 2011; 26: 2799-2806.
68. Harada T, Ohata Y, Deura I, Taniguchi F, Iwabe T, Terakawa N,. Serum cytokine levels are elevated in patients with endometriosis. WES E-Journal 2008; July; 5-8.
69. Eley A, Pacey AA, Galdiero M, Galdiero M, Galdiero F,. Can Chlamydia trachomatis directly damage your sperm? Lancet 2005; 5: 53-57.
70. Ota H, Igarashi S, Hatazawa J, Tanaka T,. Endometriosis and free radicals. Gynecol Obstet Invest 1999; 48 (Suppl 1): 29-35.