An investigation of resistance to β-lactam antimicrobials among staphylococci isolated from pigs with exudative epidermitis

BMC Veterinary Research

Volumn 9, Issue , 2013, Pages

  Park, Jeonghwa ^a   Friendship, Robert M ^a   Weese, J S ^a   Poljak, Zvonimir ^a   Dewey, Cate E ^a  

^a UNIVERSITY OF GUELPH   (Canada)

Author keywords

lactam resistance; Exudative epidermitis; mecA gene; mecC (novel mecALGA251); Methicillin resistant Staphylococcus aureus; Methicillin resistant Staphylococcus hyicus; Pigs; SCCmec type V

Indexed keywords

ANIMALIA; METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS; STAPHYLOCOCCUS; STAPHYLOCOCCUS ARLETTAE; STAPHYLOCOCCUS AUREUS; STAPHYLOCOCCUS CHROMOGENES; STAPHYLOCOCCUS COHNII; STAPHYLOCOCCUS HYICUS; STAPHYLOCOCCUS PSEUDINTERMEDIUS; SUIDAE; SUS;

AMPICILLIN; BETA LACTAM; CEFTIOFUR; CEPHALOSPORIN DERIVATIVE; PENICILLIN G;

ANIMAL; ANIMAL DISEASE; ANTIBIOTIC RESISTANCE; ARTICLE; BACTERIUM IDENTIFICATION; DISK DIFFUSION; DRUG EFFECT; EXUDATIVE EPIDERMITIS; GENETICS; MICROBIOLOGY; STAPHYLOCOCCAL SKIN INFECTION; STAPHYLOCOCCUS; STAPHYLOCOCCUS AUREUS; STAPHYLOCOCCUS HYICUS; SWINE;

AMPICILLIN; ANIMALS; BACTERIAL TYPING TECHNIQUES; BETA-LACTAM RESISTANCE; BETA-LACTAMS; CEPHALOSPORINS; DISK DIFFUSION ANTIMICROBIAL TESTS; EPIDERMITIS, EXUDATIVE, OF SWINE; PENICILLIN G; STAPHYLOCOCCAL SKIN INFECTIONS; STAPHYLOCOCCUS; STAPHYLOCOCCUS AUREUS; STAPHYLOCOCCUS HYICUS; SWINE;

EID: 84886900762     PISSN: None     EISSN: 17466148     Source Type: Journal    
DOI: 10.1186/1746-6148-9-211     Document Type: Article

References (25)

1. Wegener HC, Skov-Jensen EW. Exudative epidermitis. Diseases of Swine 2006, 675-679. Ames, Iowa: Blackwell Pub, Straw BE, Zimmerman JJ, D'Allaire S, Taylor DJ, 9.
2. Aarestrup FM, Jensen LB. Trends in antimicrobial susceptibility in relation to antimicrobial usage and presence of resistance genes in Staphylococcus hyicus isolated from exudative epidermitis in pigs. Vet Microbiol 2002, 89(1):83-94. 10.1016/S0378-1135(02)00177-3, 12223165.
3. Aarestrup FM, Oliver Duran C, Burch DG. Antimicrobial resistance in swine production. Anim Health Res Rev 2008, 9(2):135-148. 10.1017/S1466252308001503, 18983723.
4. Werckenthin C, Cardoso M, Martel JL, Schwarz S. Antimicrobial resistance in staphylococci from animals with particular reference to bovine Staphylococcus aureus, porcine Staphylococcus hyicus, and canine Staphylococcus intermedius. Vet Res 2001, 32(3-4):341-362.
5. Park J, Friendship RM, Poljak Z, Weese JS, Dewey CE. An investigation of exudative epidermitis (greasy pig disease) and antimicrobial resistance patterns of Staphylococcus hyicus and Staphylococcus aureus isolated from clinical cases. Can Vet J 2013, 54:139-144. 3552588, 23904636.
6. Anon Analysis of the baseline survey on the prevalence of methicillin-resistant Staphylococcus aureus (MRSA) in holdings with breeding pigs, in the EU, 2008 [1] - Part A: MRSA prevalence estimates. EFSA J 2009, 7(11):1376. Anon.
7. Sergio DM, Koh TH, Hsu LY, Ogden BE, Goh AL, Chow PK. Investigation of meticillin-resistant Staphylococcus aureus in pigs used for research. J Med Microbiol 2007, 56(Pt 8):1107-1109.
8. Smith TC, Male MJ, Harper AL, Kroeger JS, Tinkler GP, Moritz ED, Capuano AW, Herwaldt LA, Diekema DJ. Methicillin-resistant Staphylococcus aureus (MRSA) strain ST398 is present in midwestern U.S. swine and swine workers. PLoS One 2009, 4(1):e4258. 10.1371/journal.pone.0004258, 2626282, 19145257.
9. Khanna T, Friendship R, Dewey C, Weese JS. Methicillin resistant Staphylococcus aureus colonization in pigs and pig farmers. Vet Microbiol 2008, 128(3-4):298-303.
10. Taylor DJ, Taylor DJ. Miscellaneous Bacterial Infections. Diseases of Swine 2006, 817-846. Ames, Iowa: Blackwell Pub, Straw BE, Zimmerman JJ, D'Allaire S, Taylor DJ, 9.
11. Cameron R. Diseases of the skin. Diseases of Swine 2006, 179-198. Ames, Iowa: Blackwell Pub, Straw BE, Zimmerman JJ, D'Allaire S, Taylor DJ, 9.
12. Paterson DL, Bonomo RA. Extended-spectrum beta-lactamases: a clinical update. Clin Microbiol Rev 2005, 18(4):657-686. 10.1128/CMR.18.4.657-686.2005, 1265908, 16223952.
13. Clinical and Laboratory Standards Institute Performance Standards for Antimicrobial Disk and Dilution Susceptibility Tests for Bacteria Isolated from Animals; Approved Standard-Third Edition. CLSI document 2008, 28(8):M31-A3. Clinical and Laboratory Standards Institute.
14. Sasaki T, Tsubakishita S, Tanaka Y, Sakusabe A, Ohtsuka M, Hirotaki S, Kawakami T, Fukata T, Hiramatsu K. Multiplex-PCR method for species identification of coagulase-positive staphylococci. J Clin Microbiol 2010, 48(3):765-769. 10.1128/JCM.01232-09, 2832457, 20053855.
15. Wielders CL, Fluit AC, Brisse S, Verhoef J, Schmitz FJ. mecA gene is widely disseminated in Staphylococcus aureus population. J Clin Microbiol 2002, 40(11):3970-3975. 10.1128/JCM.40.11.3970-3975.2002, 139644, 12409360.
16. Stegger M, Andersen PS, Kearns A, Pichon B, Holmes MA, Edwards G, Laurent F, Teale C, Skov R, Larsen AR. Rapid detection, differentiation and typing of methicillin-resistant Staphylococcus aureus harbouring either mecA or the new mecA homologue mecA(LGA251). Clin Microbiol Infect 2012, 18:395-400. 10.1111/j.1469-0691.2011.03715.x, 22429460.
17. Shopsin B, Gomez M, Montgomery SO, Smith DH, Waddington M, Dodge DE, Bost DA, Riehman M, Naidich S, Kreiswirth BN. Evaluation of protein A gene polymorphic region DNA sequencing for typing of Staphylococcus aureus strains. J Clin Microbiol 1999, 37(11):3556-3563. 85690, 10523551.
18. Zhang K, McClure JA, Elsayed S, Louie T, Conly JM. Novel multiplex PCR assay for characterization and concomitant subtyping of staphylococcal cassette chromosome mec types I to V in methicillin-resistant Staphylococcus aureus. J Clin Microbiol 2005, 43(10):5026-5033. 10.1128/JCM.43.10.5026-5033.2005, 1248471, 16207957.
19. Kondo Y, Ito T, Ma XX, Watanabe S, Kreiswirth BN, Etienne J, Hiramatsu K. Combination of multiplex PCRs for staphylococcal cassette chromosome mec type assignment: rapid identification system for mec, ccr, and major differences in junkyard regions. Antimicrob Agents Chemother 2007, 51(1):264-274. 10.1128/AAC.00165-06, 1797693, 17043114.
20. Garcia-Alvarez L, Holden MTG, Lindsay H, Webb CR, Brown DF, Curran MD, Walpole E, Brooks K, Pickard DJ, Teale C, Parkhill J, Bentley SD, Edwards GF, Girvan EK, Kearns AM, Pichon B, Hill RLR, Larsen AR, Skov RL, Peacock SJ, Holmes MA. Meticillin-resistant Staphylococcus aureus with a novel mecA homologue in human and bovine populations in the UK and Denmark: a descriptive study. Lancet Infect Dis 2011, 11:595-603. 10.1016/S1473-3099(11)70126-8, 21641281.
21. Voss A. Methicillin-resistant Staphylococcus aureus in pig farming. Emerging infectious diseases 2005, 11(12):1965-1966. 10.3201/eid1112.050428, 3367632, 16485492.
22. Tsubakishita S, Kuwahara-Arai K, Sasaki T, Hiramatsu K. Origin and molecular evolution of the determinant of methicillin resistance in staphylococci. Antimicrob Agents Chemother 2010, 54(10):4352-4359. 10.1128/AAC.00356-10, 2944575, 20679504.
23. Friendship RM, Prescott JF. Drug Therapy and Prophylaxis. Diseases of Swine 2006, 1131-1143. Ames, Iowa: Blackwell Pub, Straw BE, Zimmerman JJ, D'Allaire S, Taylor DJ, 9.
24. Vanderhaeghen W, Vandendriessche S, Crombe F, Dispas M, Denis O, Hermans K, Haesebrouck F, Butaye P. Species and staphylococcal cassette chromosome mec (SCCmec) diversity among methicillin-resistant non-Staphylococcus aureus staphylococci isolated from pigs. Vet Microbiol 2012, 158(1-2):123-128.
25. Fluit AC. What to do with MRSA with a novel mec gene?. Lancet Infect Dis 2011, 11(8):580-581. 10.1016/S1473-3099(11)70180-3, 21798457.