메뉴 건너뛰기




Volumn 19, Issue 39, 2013, Pages 6604-6612

Effects of 5-HT2B, 5-HT3 and 5-HT4 receptor antagonists on gastrointestinal motor activity in dogs

Author keywords

5 hydroxytryptamine receptor antagonist; Colonic motility; Irritable bowel syndrome

Indexed keywords

ONDANSETRON; SEROTONIN; SEROTONIN 2 ANTAGONIST; SEROTONIN 3 ANTAGONIST; SEROTONIN 4 ANTAGONIST;

EID: 84886899876     PISSN: 10079327     EISSN: 22192840     Source Type: Journal    
DOI: 10.3748/wjg.v19.i39.6604     Document Type: Article
Times cited : (25)

References (45)
  • 1
    • 10644290207 scopus 로고    scopus 로고
    • Review article: Serotonin receptors and transporters-roles in normal and abnormal gastrointestinal motility
    • [PMID: 15521849]
    • Gershon MD. Review article: serotonin receptors and transporters-roles in normal and abnormal gastrointestinal motility. Aliment Pharmacol Ther 2004; 20 Suppl 7: 3-14 [PMID: 15521849]
    • (2004) Aliment Pharmacol Ther , vol.20 , Issue.SUPPL. 7 , pp. 3-14
    • Gershon, M.D.1
  • 2
    • 33846347644 scopus 로고    scopus 로고
    • The serotonin signaling system: From basic understanding to drug development for functional GI disorders
    • [PMID: 17241888 DOI: 10.1053/j.gastro.2006.11.002]
    • Gershon MD, Tack J. The serotonin signaling system: from basic understanding to drug development for functional GI disorders. Gastroenterology 2007; 132: 397-414 [PMID: 17241888 DOI: 10.1053/j.gastro.2006.11.002]
    • (2007) Gastroenterology , vol.132 , pp. 397-414
    • Gershon, M.D.1    Tack, J.2
  • 3
    • 0000670006 scopus 로고    scopus 로고
    • 5-HT (serotonin) physiology and related drugs
    • [PMID: 17024028 DOI: 10.1097/00001574-200003000-00004]
    • Gershon MD. 5-HT (serotonin) physiology and related drugs. Curr Opin Gastroenterol 2000; 16: 113-120 [PMID: 17024028 DOI: 10.1097/00001574-200003000-00004]
    • (2000) Curr Opin Gastroenterol , vol.16 , pp. 113-120
    • Gershon, M.D.1
  • 4
    • 0028042207 scopus 로고
    • Analysis of the role of 5-HT in the enteric nervous system using anti-idiotopic antibodies to 5-HT receptors
    • [PMID: 8166280]
    • Wade PR, Tamir H, Kirchgessner AL, Gershon MD. Analysis of the role of 5-HT in the enteric nervous system using anti-idiotopic antibodies to 5-HT receptors. Am J Physiol 1994; 266: G403-G416 [PMID: 8166280]
    • (1994) Am J Physiol , vol.266
    • Wade, P.R.1    Tamir, H.2    Kirchgessner, A.L.3    Gershon, M.D.4
  • 5
    • 64849088421 scopus 로고    scopus 로고
    • Role of serotonin in gastrointestinal motility and irritable bowel syndrome
    • [PMID: 19361459 DOI: 10.1016/ j.cca.2009.01.028]
    • Sikander A, Rana SV, Prasad KK. Role of serotonin in gastrointestinal motility and irritable bowel syndrome. Clin Chim Acta 2009; 403: 47-55 [PMID: 19361459 DOI: 10.1016/ j.cca.2009.01.028]
    • (2009) Clin Chim Acta , vol.403 , pp. 47-55
    • Sikander, A.1    Rana, S.V.2    Prasad, K.K.3
  • 6
    • 0034297908 scopus 로고    scopus 로고
    • Serotonin: A mediator of the braingut connection
    • [PMID: 11051338]
    • Kim DY, Camilleri M. Serotonin: a mediator of the braingut connection. Am J Gastroenterol 2000; 95: 2698-2709 [PMID: 11051338]
    • (2000) Am J Gastroenterol , vol.95 , pp. 2698-2709
    • Kim, D.Y.1    Camilleri, M.2
  • 7
    • 0032919084 scopus 로고    scopus 로고
    • Review article: Roles played by 5-hydroxytryptamine in the physiology of the bowel
    • [PMID: 10429737 DOI: 101046/j.1365-2036.1999.00002.x-i2]
    • Gershon MD. Review article: roles played by 5-hydroxytryptamine in the physiology of the bowel. Aliment Pharmacol Ther 1999; 13 Suppl 2: 15-30 [PMID: 10429737 DOI: 10.1046/j.1365-2036.1999.00002.x-i2]
    • (1999) Aliment Pharmacol Ther , vol.13 , Issue.SUPPL. 2 , pp. 15-30
    • Gershon, M.D.1
  • 9
    • 0036946561 scopus 로고    scopus 로고
    • Effects of mosapride citrate, a 5-HT4 receptor agonist, on colonic motility in conscious guinea pigs
    • [PMID: 12501007 DOI: 10.1254/jjp.90.313]
    • Inui A, Yoshikawa T, Nagai R, Yoshida N, Ito T. Effects of mosapride citrate, a 5-HT4 receptor agonist, on colonic motility in conscious guinea pigs. Jpn J Pharmacol 2002; 90: 313-320 [PMID: 12501007 DOI: 10.1254/jjp.90.313]
    • (2002) Jpn J Pharmacol , vol.90 , pp. 313-320
    • Inui, A.1    Yoshikawa, T.2    Nagai, R.3    Yoshida, N.4    Ito, T.5
  • 10
    • 0032909949 scopus 로고    scopus 로고
    • Propulsion in guinea pig colon induced by 5-hydroxytryptamine (HT) via 5-HT4 and 5-HT3 receptors
    • [PMID: 9862758]
    • Jin JG, Foxx-Orenstein AE, Grider JR. Propulsion in guinea pig colon induced by 5-hydroxytryptamine (HT) via 5-HT4 and 5-HT3 receptors. J Pharmacol Exp Ther 1999; 288: 93-97 [PMID: 9862758]
    • (1999) J Pharmacol Exp Ther , vol.288 , pp. 93-97
    • Jin, J.G.1    Foxx-Orenstein, A.E.2    Grider, J.R.3
  • 11
    • 0030981178 scopus 로고    scopus 로고
    • Effect of a selective 5-HT3 receptor agonist on gastric motility in fasted and fed dogs
    • [PMID: 9200559 DOI: 10.1016/S0014-2999(97)89660-4]
    • Nagakura Y, Ito H, Kamato T, Nishida A, Miyata K. Effect of a selective 5-HT3 receptor agonist on gastric motility in fasted and fed dogs. Eur J Pharmacol 1997; 327: 189-193 [PMID: 9200559 DOI: 10.1016/S0014-2999(97)89660-4]
    • (1997) Eur J Pharmacol , vol.327 , pp. 189-193
    • Nagakura, Y.1    Ito, H.2    Kamato, T.3    Nishida, A.4    Miyata, K.5
  • 12
    • 0033709510 scopus 로고    scopus 로고
    • 5-HT(4) receptors on cholinergic nerves involved in contractility of canine and human large intestine longitudinal muscle
    • [PMID: 11053213 DOI: 10.1038/sj.bjp.0703615]
    • Prins NH, Akkermans LM, Lefebvre RA, Schuurkes JA. 5-HT(4) receptors on cholinergic nerves involved in contractility of canine and human large intestine longitudinal muscle. Br J Pharmacol 2000; 131: 927-932 [PMID: 11053213 DOI: 10.1038/sj.bjp.0703615]
    • (2000) Br J Pharmacol , vol.131 , pp. 927-932
    • Prins, N.H.1    Akkermans, L.M.2    Lefebvre, R.A.3    Schuurkes, J.A.4
  • 13
    • 79952305589 scopus 로고    scopus 로고
    • The role of stress on physiologic responses and clinical symptoms in irritable bowel syndrome
    • [PMID: 21256129 DOI: 10.1053/ j.gastro.2011.01.032]
    • Chang L. The role of stress on physiologic responses and clinical symptoms in irritable bowel syndrome. Gastroenterology 2011; 140: 761-765 [PMID: 21256129 DOI: 10.1053/ j.gastro.2011.01.032]
    • (2011) Gastroenterology , vol.140 , pp. 761-765
    • Chang, L.1
  • 14
    • 42249111897 scopus 로고    scopus 로고
    • Effects of serotonin 5-HT3 receptor antagonists on stress-induced colonic hyperalgesia and diarrhoea in rats: A comparative study with opioid receptor agonists, a muscarinic receptor antagonist and a synthetic polymer
    • [PMID: 18221252 DOI: 10.1111/j.1365-2982.2007.01069.x]
    • Hirata T, Keto Y, Nakata M, Takeuchi A, Funatsu T, Akuzawa S, Sasamata M, Miyata K. Effects of serotonin 5-HT3 receptor antagonists on stress-induced colonic hyperalgesia and diarrhoea in rats: a comparative study with opioid receptor agonists, a muscarinic receptor antagonist and a synthetic polymer. Neurogastroenterol Motil 2008; 20: 557-565 [PMID: 18221252 DOI: 10.1111/j.1365-2982.2007.01069.x]
    • (2008) Neurogastroenterol Motil , vol.20 , pp. 557-565
    • Hirata, T.1    Keto, Y.2    Nakata, M.3    Takeuchi, A.4    Funatsu, T.5    Akuzawa, S.6    Sasamata, M.7    Miyata, K.8
  • 15
    • 34147129583 scopus 로고    scopus 로고
    • Restraint stress stimulates colonic motility via central corticotropinreleasing factor and peripheral 5-HT3 receptors in conscious rats
    • [PMID: 17158256 DOI: 10.1152/ajpgi. 00419.2006]
    • Nakade Y, Fukuda H, Iwa M, Tsukamoto K, Yanagi H, Yamamura T, Mantyh C, Pappas TN, Takahashi T. Restraint stress stimulates colonic motility via central corticotropinreleasing factor and peripheral 5-HT3 receptors in conscious rats. Am J Physiol Gastrointest Liver Physiol 2007; 292: G1037-G1044 [PMID: 17158256 DOI: 10.1152/ajpgi. 00419.2006]
    • (2007) Am J Physiol Gastrointest Liver Physiol , vol.292
    • Nakade, Y.1    Fukuda, H.2    Iwa, M.3    Tsukamoto, K.4    Yanagi, H.5    Yamamura, T.6    Mantyh, C.7    Pappas, T.N.8    Takahashi, T.9
  • 16
    • 0032061274 scopus 로고    scopus 로고
    • Involvement of the 5-HT3 receptor in CRH-induce defecation in rats
    • [PMID: 9612262]
    • Miyata K, Ito H, Fukudo S. Involvement of the 5-HT3 receptor in CRH-induce defecation in rats. Am J Physiol 1998; 274: G827-G831 [PMID: 9612262]
    • (1998) Am J Physiol , vol.274
    • Miyata, K.1    Ito, H.2    Fukudo, S.3
  • 17
    • 0026060943 scopus 로고
    • Effects of 5-hydroxytryptamine 3 receptor antagonists on gastrointestinal motor activity in conscious dogs
    • [PMID: 1846418]
    • Yoshida N, Mizumoto A, Iwanaga Y, Itoh Z. Effects of 5-hydroxytryptamine 3 receptor antagonists on gastrointestinal motor activity in conscious dogs. J Pharmacol Exp Ther 1991; 256: 272-278 [PMID: 1846418]
    • (1991) J Pharmacol Exp Ther , vol.256 , pp. 272-278
    • Yoshida, N.1    Mizumoto, A.2    Iwanaga, Y.3    Itoh, Z.4
  • 18
    • 77952321561 scopus 로고    scopus 로고
    • Intracolonic capsaicin stimulates colonic motility and defecation in conscious dogs
    • [PMID: 20079916 DOI: 10.1016/j.surg.2009.11.019]
    • Hayashi K, Shibata C, Nagao M, Sato M, Kakyo M, Kinouchi M, Saijo F, Miura K, Ogawa H, Sasaki I. Intracolonic capsaicin stimulates colonic motility and defecation in conscious dogs. Surgery 2010; 147: 789-797 [PMID: 20079916 DOI: 10.1016/j.surg.2009.11.019]
    • (2010) Surgery , vol.147 , pp. 789-797
    • Hayashi, K.1    Shibata, C.2    Nagao, M.3    Sato, M.4    Kakyo, M.5    Kinouchi, M.6    Saijo, F.7    Miura, K.8    Ogawa, H.9    Sasaki, I.10
  • 19
    • 0028295092 scopus 로고
    • Serotonergic mediation of postprandial colonic tonic and phasic responses in humans
    • [PMID: 8174993 DOI: 10.1136/gut.35.4.536]
    • von der Ohe MR, Hanson RB, Camilleri M. Serotonergic mediation of postprandial colonic tonic and phasic responses in humans. Gut 1994; 35: 536-541 [PMID: 8174993 DOI: 10.1136/gut.35.4.536]
    • (1994) Gut , vol.35 , pp. 536-541
    • von der Ohe, M.R.1    Hanson, R.B.2    Camilleri, M.3
  • 20
  • 21
    • 0025219706 scopus 로고
    • GR 38032F (ondansetron), a selective 5HT3 receptor antagonist, slows colonic transit in healthy man
    • [PMID: 2138532 DOI: 10.1007/BF01536922]
    • Talley NJ, Phillips SF, Haddad A, Miller LJ, Twomey C, Zinsmeister AR, MacCarty RL, Ciociola A. GR 38032F (ondansetron), a selective 5HT3 receptor antagonist, slows colonic transit in healthy man. Dig Dis Sci 1990; 35: 477-480 [PMID: 2138532 DOI: 10.1007/BF01536922]
    • (1990) Dig Dis Sci , vol.35 , pp. 477-480
    • Talley, N.J.1    Phillips, S.F.2    Haddad, A.3    Miller, L.J.4    Twomey, C.5    Zinsmeister, A.R.6    McCarty, R.L.7    Ciociola, A.8
  • 22
    • 0024474193 scopus 로고
    • Effect of selective 5HT3 antagonist (GR 38032F) on small intestinal transit and release of gastrointestinal peptides
    • [PMID: 2529108 DOI: 10.1007/BF01537102]
    • Talley NJ, Phillips SF, Haddad A, Miller LJ, Twomey C, Zinsmeister AR, Ciociola A. Effect of selective 5HT3 antagonist (GR 38032F) on small intestinal transit and release of gastrointestinal peptides. Dig Dis Sci 1989; 34: 1511-1515 [PMID: 2529108 DOI: 10.1007/BF01537102]
    • (1989) Dig Dis Sci , vol.34 , pp. 1511-1515
    • Talley, N.J.1    Phillips, S.F.2    Haddad, A.3    Miller, L.J.4    Twomey, C.5    Zinsmeister, A.R.6    Ciociola, A.7
  • 23
    • 0024999306 scopus 로고
    • Colonic transit in man is slowed by ondansetron (GR38032F), a selective 5-hydroxytryptamine receptor (type 3) antagonist
    • [PMID: 2151757 DOI: 10.1111/j.1365-2036.1990.tb00458.x]
    • Gore S, Gilmore IT, Haigh CG, Brownless SM, Stockdale H, Morris AI. Colonic transit in man is slowed by ondansetron (GR38032F), a selective 5-hydroxytryptamine receptor (type 3) antagonist. Aliment Pharmacol Ther 1990; 4: 139-144 [PMID: 2151757 DOI: 10.1111/j.1365-2036.1990.tb00458.x]
    • (1990) Aliment Pharmacol Ther , vol.4 , pp. 139-144
    • Gore, S.1    Gilmore, I.T.2    Haigh, C.G.3    Brownless, S.M.4    Stockdale, H.5    Morris, A.I.6
  • 24
    • 0026741853 scopus 로고
    • Selective 5-hydroxytryptamine type 3 receptor antagonism with ondansetron as treatment for diarrhea-predominant irritable bowel syndrome: A pilot study
    • [PMID: 1434911 DOI: 10.1016/ S0025-6196(12)60797-6]
    • Steadman CJ, Talley NJ, Phillips SF, Zinsmeister AR. Selective 5-hydroxytryptamine type 3 receptor antagonism with ondansetron as treatment for diarrhea-predominant irritable bowel syndrome: a pilot study. Mayo Clin Proc 1992; 67: 732-738 [PMID: 1434911 DOI: 10.1016/ S0025-6196(12)60797-6]
    • (1992) Mayo Clin Proc , vol.67 , pp. 732-738
    • Steadman, C.J.1    Talley, N.J.2    Phillips, S.F.3    Zinsmeister, A.R.4
  • 26
    • 74549184061 scopus 로고    scopus 로고
    • A selective, high affinity 5-HT 2B receptor antagonist inhibits visceral hypersensitivity in rats
    • [PMID: 19740115 DOI: 10.1111/j.1365-2982.2009.01395.x]
    • Ohashi-Doi K, Himaki D, Nagao K, Kawai M, Gale JD, Furness JB, Kurebayashi Y. A selective, high affinity 5-HT 2B receptor antagonist inhibits visceral hypersensitivity in rats. Neurogastroenterol Motil 2010; 22: e69-e76 [PMID: 19740115 DOI: 10.1111/j.1365-2982.2009.01395.x]
    • (2010) Neurogastroenterol Motil , vol.22
    • Ohashi-Doi, K.1    Himaki, D.2    Nagao, K.3    Kawai, M.4    Gale, J.D.5    Furness, J.B.6    Kurebayashi, Y.7
  • 27
    • 53449094757 scopus 로고    scopus 로고
    • Serotonin and GI clinical disorders
    • [PMID: 18687345 DOI: 10.1016/ j.neuropharm.2008.07.016]
    • Spiller R. Serotonin and GI clinical disorders. Neuropharmacology 2008; 55: 1072-1080 [PMID: 18687345 DOI: 10.1016/ j.neuropharm.2008.07.016]
    • (2008) Neuropharmacology , vol.55 , pp. 1072-1080
    • Spiller, R.1
  • 28
    • 0035894575 scopus 로고    scopus 로고
    • Serotoninergic neuroenteric modulators
    • [PMID: 11755632 DOI: 10.1016/ S0140-6736(01)07103-3]
    • Talley NJ. Serotoninergic neuroenteric modulators. Lancet 2001; 358: 2061-2068 [PMID: 11755632 DOI: 10.1016/ S0140-6736(01)07103-3]
    • (2001) Lancet , vol.358 , pp. 2061-2068
    • Talley, N.J.1
  • 29
    • 0032772797 scopus 로고    scopus 로고
    • Pharmacological characterization of 5-HT4 receptors mediating relaxation of canine isolated rectum circular smooth muscle
    • [PMID: 10455293 DOI: 10.1038/sj.bjp.0702665]
    • Prins NH, Van Haselen JF, Lefebvre RA, Briejer MR, Akkermans LM, Schuurkes JA. Pharmacological characterization of 5-HT4 receptors mediating relaxation of canine isolated rectum circular smooth muscle. Br J Pharmacol 1999; 127: 1431-1437 [PMID: 10455293 DOI: 10.1038/sj.bjp.0702665]
    • (1999) Br J Pharmacol , vol.127 , pp. 1431-1437
    • Prins, N.H.1    van Haselen, J.F.2    Lefebvre, R.A.3    Briejer, M.R.4    Akkermans, L.M.5    Schuurkes, J.A.6
  • 30
    • 0029058239 scopus 로고
    • A comparative study of functional 5-HT4 receptors in human colon, rat oesophagus and rat ileum
    • [PMID: 7647983 DOI: 10.1111/j.1476-5381.1995.tb16318.x]
    • McLean PG, Coupar IM, Molenaar P. A comparative study of functional 5-HT4 receptors in human colon, rat oesophagus and rat ileum. Br J Pharmacol 1995; 115: 47-56 [PMID: 7647983 DOI: 10.1111/j.1476-5381.1995.tb16318.x]
    • (1995) Br J Pharmacol , vol.115 , pp. 47-56
    • McLean, P.G.1    Coupar, I.M.2    Molenaar, P.3
  • 31
    • 0028989385 scopus 로고
    • Differences in response to 5-HT4 receptor agonists and antagonists of the 5-HT4-like receptor in human colon circular smooth muscle
    • [PMID: 7647972 DOI: 10.1111/j.1476-5381.1995.tb16335.x]
    • Tam FS, Hillier K, Bunce KT, Grossman C. Differences in response to 5-HT4 receptor agonists and antagonists of the 5-HT4-like receptor in human colon circular smooth muscle. Br J Pharmacol 1995; 115: 172-176 [PMID: 7647972 DOI: 10.1111/j.1476-5381.1995.tb16335.x]
    • (1995) Br J Pharmacol , vol.115 , pp. 172-176
    • Tam, F.S.1    Hillier, K.2    Bunce, K.T.3    Grossman, C.4
  • 32
    • 0017764219 scopus 로고
    • An extraluminal force transducer for recording contractile activity of the gastrointestinal smooth muscle in the conscious dogs: Its construction and implantation
    • [PMID: 590700]
    • Itoh Z, Honda R, Takeuchi S, Aizawa I, Takayanagi R. An extraluminal force transducer for recording contractile activity of the gastrointestinal smooth muscle in the conscious dogs: its construction and implantation. Gastroenterol Jpn 1977; 12: 275-283 [PMID: 590700]
    • (1977) Gastroenterol Jpn , vol.12 , pp. 275-283
    • Itoh, Z.1    Honda, R.2    Takeuchi, S.3    Aizawa, I.4    Takayanagi, R.5
  • 34
    • 84970916994 scopus 로고    scopus 로고
    • The novel 5-HT2B receptor antagonist, RQ-00310941, attenuates visceral hypersensitivity and abnormal defecation in rat models
    • S-607, [DOI: 10.1016/S0016-5085(11)62513-4]
    • Takahashi N, Inagaki K, Taniguchi K, Sakaguchi Y, Kawamura K. The novel 5-HT2B receptor antagonist, RQ-00310941, attenuates visceral hypersensitivity and abnormal defecation in rat models. Gastroenterology 2011; 140: S-607 [DOI: 10.1016/S0016-5085(11)62513-4]
    • (2011) Gastroenterology , vol.140
    • Takahashi, N.1    Inagaki, K.2    Taniguchi, K.3    Sakaguchi, Y.4    Kawamura, K.5
  • 35
    • 0018091456 scopus 로고
    • Characteristic motor activity of the gastrointestinal tract in fasted conscious dogs measured by implanted force transducers
    • [PMID: 665611 DOI: 10.1007/ BF01072323]
    • Itoh Z, Takeuchi S, Aizawa I, Takayanagi R. Characteristic motor activity of the gastrointestinal tract in fasted conscious dogs measured by implanted force transducers. Am J Dig Dis 1978; 23: 229-238 [PMID: 665611 DOI: 10.1007/ BF01072323]
    • (1978) Am J Dig Dis , vol.23 , pp. 229-238
    • Itoh, Z.1    Takeuchi, S.2    Aizawa, I.3    Takayanagi, R.4
  • 36
    • 0029993362 scopus 로고    scopus 로고
    • Characterization of 5-hydroxytryptamine (5-HT) receptor subtypes influencing colonic motility in conscious dogs
    • [PMID: 8740141 DOI: 10.1007/BF00169167]
    • Nagakura Y, Kamato T, Nishida A, Ito H, Yamano M, Miyata K. Characterization of 5-hydroxytryptamine (5-HT) receptor subtypes influencing colonic motility in conscious dogs. Naunyn Schmiedebergs Arch Pharmacol 1996; 353: 489-498 [PMID: 8740141 DOI: 10.1007/BF00169167]
    • (1996) Naunyn Schmiedebergs Arch Pharmacol , vol.353 , pp. 489-498
    • Nagakura, Y.1    Kamato, T.2    Nishida, A.3    Ito, H.4    Yamano, M.5    Miyata, K.6
  • 37
    • 34247141035 scopus 로고    scopus 로고
    • Wood creosote prevents CRF-induced motility via 5-HT3 receptors in proximal and 5-HT4 receptors in distal colon in rats
    • [PMID: 17182287 DOI: 10.1016/j.autneu.2006.11.002]
    • Ataka K, Kuge T, Fujino K, Takahashi T, Fujimiya M. Wood creosote prevents CRF-induced motility via 5-HT3 receptors in proximal and 5-HT4 receptors in distal colon in rats. Auton Neurosci 2007; 133: 136-145 [PMID: 17182287 DOI: 10.1016/j.autneu.2006.11.002]
    • (2007) Auton Neurosci , vol.133 , pp. 136-145
    • Ataka, K.1    Kuge, T.2    Fujino, K.3    Takahashi, T.4    Fujimiya, M.5
  • 39
    • 62949247401 scopus 로고    scopus 로고
    • Localized release of serotonin (5-hydroxytryptamine) by a fecal pellet regulates migrating motor complexes in murine colon
    • [PMID: 19138686 DOI: 10.1053/j.gastro.2008.12.010]
    • Heredia DJ, Dickson EJ, Bayguinov PO, Hennig GW, Smith TK. Localized release of serotonin (5-hydroxytryptamine) by a fecal pellet regulates migrating motor complexes in murine colon. Gastroenterology 2009; 136: 1328-1338 [PMID: 19138686 DOI: 10.1053/j.gastro.2008.12.010]
    • (2009) Gastroenterology , vol.136 , pp. 1328-1338
    • Heredia, D.J.1    Dickson, E.J.2    Bayguinov, P.O.3    Hennig, G.W.4    Smith, T.K.5
  • 40
    • 77954370585 scopus 로고    scopus 로고
    • Critical role of 5-HT1A, 5-HT3, and 5-HT7 receptor subtypes in the initiation, generation, and propagation of the murine colonic migrating motor complex
    • [PMID: 20413719 DOI: 10.1152/ajpgi.00496.2009]
    • Dickson EJ, Heredia DJ, Smith TK. Critical role of 5-HT1A, 5-HT3, and 5-HT7 receptor subtypes in the initiation, generation, and propagation of the murine colonic migrating motor complex. Am J Physiol Gastrointest Liver Physiol 2010; 299: G144-G157 [PMID: 20413719 DOI: 10.1152/ajpgi.00496.2009]
    • (2010) Am J Physiol Gastrointest Liver Physiol , vol.299
    • Dickson, E.J.1    Heredia, D.J.2    Smith, T.K.3
  • 41
    • 0033755876 scopus 로고    scopus 로고
    • Effects of a serotonin 5-HT(4) receptor antagonist SB-207266 on gastrointestinal motor and sensory function in humans
    • [PMID: 11034583 DOI: 10.1136/gut.47.5.667]
    • Bharucha AE, Camilleri M, Haydock S, Ferber I, Burton D, Cooper S, Tompson D, Fitzpatrick K, Higgins R, Zinsmeister AR. Effects of a serotonin 5-HT(4) receptor antagonist SB-207266 on gastrointestinal motor and sensory function in humans. Gut 2000; 47: 667-674 [PMID: 11034583 DOI: 10.1136/gut.47.5.667]
    • (2000) Gut , vol.47 , pp. 667-674
    • Bharucha, A.E.1    Camilleri, M.2    Haydock, S.3    Ferber, I.4    Burton, D.5    Cooper, S.6    Tompson, D.7    Fitzpatrick, K.8    Higgins, R.9    Zinsmeister, A.R.10
  • 42
    • 77953988261 scopus 로고    scopus 로고
    • Colonoscopy as an adjunctive method for the diagnosis of irritable bowel syndrome: Focus on pain perception
    • [PMID: 20594249 DOI: 10.1111/j.1440-1746.2010.06338.x]
    • Kim ES, Cheon JH, Park JJ, Moon CM, Hong SP, Kim TI, Kim WH. Colonoscopy as an adjunctive method for the diagnosis of irritable bowel syndrome: focus on pain perception. J Gastroenterol Hepatol 2010; 25: 1232-1238 [PMID: 20594249 DOI: 10.1111/j.1440-1746.2010.06338.x]
    • (2010) J Gastroenterol Hepatol , vol.25 , pp. 1232-1238
    • Kim, E.S.1    Cheon, J.H.2    Park, J.J.3    Moon, C.M.4    Hong, S.P.5    Kim, T.I.6    Kim, W.H.7
  • 43
    • 69249230884 scopus 로고    scopus 로고
    • Inhibition of colonic motility and defecation by RS-127445 suggests an involvement of the 5-HT2B receptor in rodent large bowel physiology
    • [PMID: 19371340 DOI: 10.1111/ j.1476-5381.2009.00155.x]
    • Bassil AK, Taylor CM, Bolton VJ, Gray KM, Brown JD, Cutler L, Summerfield SG, Bruton G, Winchester WJ, Lee K, Sanger GJ. Inhibition of colonic motility and defecation by RS-127445 suggests an involvement of the 5-HT2B receptor in rodent large bowel physiology. Br J Pharmacol 2009; 158: 252-258 [PMID: 19371340 DOI: 10.1111/ j.1476-5381.2009.00155.x]
    • (2009) Br J Pharmacol , vol.158 , pp. 252-258
    • Bassil, A.K.1    Taylor, C.M.2    Bolton, V.J.3    Gray, K.M.4    Brown, J.D.5    Cutler, L.6    Summerfield, S.G.7    Bruton, G.8    Winchester, W.J.9    Lee, K.10    Sanger, G.J.11
  • 44
    • 0034768022 scopus 로고    scopus 로고
    • Effects of the enterokinetic prucalopride (R093877) on colonic motility in fasted dogs
    • [PMID: 11696108 DOI: 10.1046/j.1365-2982.2001.00280.x]
    • Briejer MR, Prins NH, Schuurkes JA. Effects of the enterokinetic prucalopride (R093877) on colonic motility in fasted dogs. Neurogastroenterol Motil 2001; 13: 465-472 [PMID: 11696108 DOI: 10.1046/j.1365-2982.2001.00280.x]
    • (2001) Neurogastroenterol Motil , vol.13 , pp. 465-472
    • Briejer, M.R.1    Prins, N.H.2    Schuurkes, J.A.3
  • 45
    • 0025223666 scopus 로고
    • Differences in control of descending inhibition in the proximal and distal regions of rat colon
    • [PMID: 2085703 DOI: 10.1111/j.1476-5381.1990. tb14198.x]
    • Hata F, Kataoka T, Takeuchi T, Yagasaki O, Yamano N. Differences in control of descending inhibition in the proximal and distal regions of rat colon. Br J Pharmacol 1990; 101: 1011-1015 [PMID: 2085703 DOI: 10.1111/j.1476-5381.1990. tb14198.x]
    • (1990) Br J Pharmacol , vol.101 , pp. 1011-1015
    • Hata, F.1    Kataoka, T.2    Takeuchi, T.3    Yagasaki, O.4    Yamano, N.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.