Intranasal ketamine for analgesia in the emergency department: A prospective observational series

Academic Emergency Medicine

Volumn 20, Issue 10, 2013, Pages 1050-1054

  Andolfatto, Gary ^a,b   Willman, Elaine ^a   Joo, Daniel ^a,b   Miller, Philip ^a,b   Wong, Wai Ben ^a,b   Koehn, Martha ^a,b   Dobson, Raea ^a   Angus, Eric ^a,b   Moadebi, Susanne ^a,b  

^a UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^b LIONS GATE HOSPITAL   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

KETAMINE; OPIATE;

ADOLESCENT; ADULT; AGED; ANALGESIA; ARTICLE; CHILD; CLINICAL ARTICLE; DIZZINESS; DRUG EFFICACY; DRUG INDUCED HEADACHE; DRUG SAFETY; EMERGENCY CARE; EMERGENCY WARD; FATIGUE; FEMALE; HALLUCINATION; HEARING; HUMAN; MALE; MOOD CHANGE; NAUSEA; OBSERVATIONAL STUDY; PRIORITY JOURNAL; PROSPECTIVE STUDY; SIDE EFFECT; VISUAL ANALOG SCALE; VITAL SIGN;

ADMINISTRATION, INTRANASAL; ADOLESCENT; ADULT; AGED; ANALGESIA; ANALGESICS; CHILD; EMERGENCY SERVICE, HOSPITAL; FEMALE; HUMANS; KETAMINE; MALE; MIDDLE AGED; PAIN MANAGEMENT; PAIN MEASUREMENT; PROSPECTIVE STUDIES; TREATMENT OUTCOME; YOUNG ADULT;

EID: 84886894460     PISSN: 10696563     EISSN: 15532712     Source Type: Journal    
DOI: 10.1111/acem.12229     Document Type: Article

References (10)

1. Woolf CJ, Thompson SW,. The induction and maintenance of central sensitization is dependent on N-methyl-n-aspartic acid receptor activation: implications for the treatment of post-injury pain hypersensitivity states. Pain. 1991; 44: 293-9.
2. Yanagihara Y, Ohtani M, Kariya S, et al. Plasma concentration profiles of ketamine and norketamine after administration of various ketamine preparations to healthy Japanese volunteers. Biopharm Drug Dispos. 2003; 24: 37-43.
3. Punkett A, Turabi A, Wilkinson I,. Battlefield analgesia: current trends and concepts in pain treatment in US military casualties. Pain Manage. 2012; 2: 231-8.
4. Todd KH, Funk KG, Funk JP, Bonacci R,. Clinical significance of reported changes in pain severity. Ann Emerg Med. 1996; 27: 485-9.
5. Christenson K, Rogers E, Green GA, et al. Safety and efficacy of intranasal ketamine for acute postoperative pain. Acute Pain. 2007; 9: 183-92.
6. Eide PK, Jorum E, Stubhaug A, Bremnes J, Breivik H,. Relief of post-herpetic neuralgia with the N-methyl-D-aspartic acid receptor antagonist ketamine: a double-blind, cross-over comparison with morphine and placebo. Pain. 1994; 58: 347-54.
7. Holdgate A, Cao A, Lo KM,. The implementation of intranasal fentanyl for children in a mixed adult and pediatric emergency department reduces time to analgesic administration. Acad Emerg Med. 2010; 17: 214-7.
8. Carr DB, Goudas LC, Denman WT, et al. Safety and efficacy of intranasal ketamine for the treatment of breakthrough pain in patients with chronic pain: a randomized, double-blind, placebo-controlled, crossover study. Pain. 2004; 108: 17-27.
9. Huge V, Lauchart M, Mageri W, et al. Effects of low-dose intranasal (S)-ketamine in patients with neuropathic pain. Eur J Pain. 2010; 14: 387-94.
10. Ngai B, Ducharme J,. Documented use of analgesics in the emergency department and upon release of patients with extremity fractures. Acad Emerg Med. 1997; 4: 1176-8.