메뉴 건너뛰기




Volumn 40, Issue 5, 2013, Pages 549-553

Clinical translation in multiple myeloma: From bench to bedside

Author keywords

[No Author keywords available]

Indexed keywords

BORTEZOMIB; CARMUSTINE; CASPASE 8; CYCLOPHOSPHAMIDE; DEXAMETHASONE; DOXORUBICIN; LENALIDOMIDE; MELPHALAN; PREDNISONE; THALIDOMIDE; VASCULOTROPIN; VINCRISTINE;

EID: 84886879230     PISSN: 00937754     EISSN: None     Source Type: Journal    
DOI: 10.1053/j.seminoncol.2013.07.009     Document Type: Article
Times cited : (7)

References (57)
  • 1
    • 41949130070 scopus 로고    scopus 로고
    • Improved survival in multiple myeloma and the impact of novel therapies
    • S.K. Kumar, S.V. Rajkumar, and A. Dispenzieri Improved survival in multiple myeloma and the impact of novel therapies Blood 111 5 2008 2516 2520
    • (2008) Blood , vol.111 , Issue.5 , pp. 2516-2520
    • Kumar, S.K.1    Rajkumar, S.V.2    Dispenzieri, A.3
  • 2
    • 78651313678 scopus 로고    scopus 로고
    • Novel agents improve survival of transplant patients with multiple myeloma including those with high-risk disease defined by early relapse (<12 months)
    • C.P. Venner, J.M. Connors, and H.J. Sutherland Novel agents improve survival of transplant patients with multiple myeloma including those with high-risk disease defined by early relapse (<12 months) Leuk Lymphoma 52 1 2011 34 41
    • (2011) Leuk Lymphoma , vol.52 , Issue.1 , pp. 34-41
    • Venner, C.P.1    Connors, J.M.2    Sutherland, H.J.3
  • 3
    • 84858852342 scopus 로고
    • A case of multiple myeloma
    • J.H. Wright A case of multiple myeloma J Boston Soc Med Sci 4 8 1900 195 204
    • (1900) J Boston Soc Med Sci , vol.4 , Issue.8 , pp. 195-204
    • Wright, J.H.1
  • 4
    • 0006238221 scopus 로고
    • Electrophoretic patterns of normal and pathological human blood serum and plasma
    • L.G. Longsworth, T. Shedlovsky, and D.A. Macinnes Electrophoretic patterns of normal and pathological human blood serum and plasma J Exp Med 70 4 1939 399 413
    • (1939) J Exp Med , vol.70 , Issue.4 , pp. 399-413
    • Longsworth, L.G.1    Shedlovsky, T.2    Macinnes, D.A.3
  • 6
    • 31344444514 scopus 로고
    • Evaluation of new chemotherapeutic agents in the treatment of multiple myeloma. IV. L-Phenylalanine mustard (NSC-8806)
    • D.E. Bergsagel, C.C. Sprague, C. Austin, and K.M. Griffith Evaluation of new chemotherapeutic agents in the treatment of multiple myeloma. IV. L-Phenylalanine mustard (NSC-8806) Cancer Chemother Rep 21 1962 87 99
    • (1962) Cancer Chemother Rep , vol.21 , pp. 87-99
    • Bergsagel, D.E.1    Sprague, C.C.2    Austin, C.3    Griffith, K.M.4
  • 7
    • 0014104626 scopus 로고
    • Melphalan in multiple myeloma
    • B. Hoogstraten, P.R. Sheehe, and J. Cuttner Melphalan in multiple myeloma Blood 30 1 1967 74 83
    • (1967) Blood , vol.30 , Issue.1 , pp. 74-83
    • Hoogstraten, B.1    Sheehe, P.R.2    Cuttner, J.3
  • 8
    • 0001653947 scopus 로고
    • Multiple myeloma. II. Analysis of cyclophosphamide therapy in 165 patients
    • D.R. Korst, G.O. Clifford, W.M. Fowler, J. Louis, J. Will, and H.E. Wilson Multiple myeloma. II. Analysis of cyclophosphamide therapy in 165 patients JAMA 189 1964 758 762
    • (1964) JAMA , vol.189 , pp. 758-762
    • Korst, D.R.1    Clifford, G.O.2    Fowler, W.M.3    Louis, J.4    Will, J.5    Wilson, H.E.6
  • 9
    • 77954086740 scopus 로고
    • Prolonged remission of myeloma with cyclophosphamide
    • C.R. Tourtellotte, and M.K. Call Prolonged remission of myeloma with cyclophosphamide Arch Intern Med 113 1964 758 763
    • (1964) Arch Intern Med , vol.113 , pp. 758-763
    • Tourtellotte, C.R.1    Call, M.K.2
  • 10
    • 0014098383 scopus 로고
    • Intermittent high-dose prednisone (NSC-10023) therapy for multiple myeloma
    • S.E. Salmon, R.K. Shadduck, and A. Shilling Intermittent high-dose prednisone (NSC-10023) therapy for multiple myeloma Cancer Chemother Rep 51 1967 179 187
    • (1967) Cancer Chemother Rep , vol.51 , pp. 179-187
    • Salmon, S.E.1    Shadduck, R.K.2    Shilling, A.3
  • 11
    • 12644304424 scopus 로고
    • A comparison of the effect of prednisone and a placebo in the treartment of multiple myeloma
    • R.E. Maas A comparison of the effect of prednisone and a placebo in the treartment of multiple myeloma Cancer Chemother Rep 16 1962 257 259
    • (1962) Cancer Chemother Rep , vol.16 , pp. 257-259
    • Maas, R.E.1
  • 13
    • 0014661330 scopus 로고
    • Treatment for multiple myeloma. Combination chemotherapy with different melphalan dose regimens
    • R. Alexanian, A. Haut, and A.U. Khan Treatment for multiple myeloma. Combination chemotherapy with different melphalan dose regimens JAMA 208 9 1969 1680 1685
    • (1969) JAMA , vol.208 , Issue.9 , pp. 1680-1685
    • Alexanian, R.1    Haut, A.2    Khan, A.U.3
  • 14
    • 0016153826 scopus 로고
    • Proceedings: Combination chemotherapy of multiple myeloma with alkeran, cytoxan, vincristine, prednisone, and BCNU
    • B.J. Lee, G. Sahakian, B.D. Clarkson, and I.H. Krakhoff Proceedings: combination chemotherapy of multiple myeloma with alkeran, cytoxan, vincristine, prednisone, and BCNU Cancer 1974 33 1974 533 538
    • (1974) Cancer , vol.1974 , Issue.33 , pp. 533-538
    • Lee, B.J.1    Sahakian, G.2    Clarkson, B.D.3    Krakhoff, I.H.4
  • 15
    • 0024357763 scopus 로고
    • Infusion of vincristine and doxorubicin with oral dexamethasone as first-line therapy for multiple myeloma
    • D. Samson, E. Gaminara, and A. Newland Infusion of vincristine and doxorubicin with oral dexamethasone as first-line therapy for multiple myeloma Lancet ii 1989 882 885
    • (1989) Lancet , vol.II , pp. 882-885
    • Samson, D.1    Gaminara, E.2    Newland, A.3
  • 16
    • 0344076348 scopus 로고    scopus 로고
    • Combination chemotherapy versus melphalan plus prednisone as treatment for multiple myeloma: An overview of 6,633 patients from 27 randomized trials
    • Myeloma Trialists' Collaborative Group
    • Myeloma Trialists' Collaborative Group Combination chemotherapy versus melphalan plus prednisone as treatment for multiple myeloma: an overview of 6,633 patients from 27 randomized trials J Clin Oncol 16 1998 3832 3842
    • (1998) J Clin Oncol , vol.16 , pp. 3832-3842
  • 17
    • 17944381821 scopus 로고    scopus 로고
    • Increased conventional chemotherapy does not improve survival in multiple myeloma: Long-term results of two PETHEMA trials including 914 patients
    • J. Blade, J. San Miguel, and M. Fontanillas Increased conventional chemotherapy does not improve survival in multiple myeloma: long-term results of two PETHEMA trials including 914 patients Hematol J 2 2001 272 278
    • (2001) Hematol J , vol.2 , pp. 272-278
    • Blade, J.1    San Miguel, J.2    Fontanillas, M.3
  • 18
    • 0028362802 scopus 로고
    • Bone marrow angiogenesis and progression in multiple myeloma
    • A. Vacca, D. Ribatti, and L. Roncali Bone marrow angiogenesis and progression in multiple myeloma Br J Haematol 87 1994 503 508
    • (1994) Br J Haematol , vol.87 , pp. 503-508
    • Vacca, A.1    Ribatti, D.2    Roncali, L.3
  • 19
    • 0029146128 scopus 로고
    • Bone marrow of patients with active multiple myeloma: Angiogenesis and plasma cell adhesion molecules LFA-1, VLA-4, LAM-1, and CD44
    • A. Vacca, M. Di Loreto, and D. Ribatti Bone marrow of patients with active multiple myeloma: angiogenesis and plasma cell adhesion molecules LFA-1, VLA-4, LAM-1, and CD44 Am J Hematol 50 1 1995 9 14
    • (1995) Am J Hematol , vol.50 , Issue.1 , pp. 9-14
    • Vacca, A.1    Di Loreto, M.2    Ribatti, D.3
  • 21
    • 0032889225 scopus 로고    scopus 로고
    • Combination oral antiangiogenic therapy with thalidomide and sulindac inhibits tumour growth in rabbits
    • H.M. Verheul, D. Panigrahy, J. Yuan, and R.J. D'Amato Combination oral antiangiogenic therapy with thalidomide and sulindac inhibits tumour growth in rabbits Br J Cancer 79 1 1999 114 118
    • (1999) Br J Cancer , vol.79 , Issue.1 , pp. 114-118
    • Verheul, H.M.1    Panigrahy, D.2    Yuan, J.3    D'Amato, R.J.4
  • 22
    • 0032748385 scopus 로고    scopus 로고
    • Antitumor activity of thalidomide in refractory multiple myeloma
    • S. Singhal, J. Mehta, and R. Desikan Antitumor activity of thalidomide in refractory multiple myeloma N Engl J Med 341 21 1999 1565 1571
    • (1999) N Engl J Med , vol.341 , Issue.21 , pp. 1565-1571
    • Singhal, S.1    Mehta, J.2    Desikan, R.3
  • 23
    • 0034331194 scopus 로고    scopus 로고
    • Thalidomide and its analogs overcome drug resistance of human multiple myeloma cells to conventional therapy
    • T. Hideshima, D. Chauhan, and Y. Shima Thalidomide and its analogs overcome drug resistance of human multiple myeloma cells to conventional therapy Blood 96 9 2000 2943 2950
    • (2000) Blood , vol.96 , Issue.9 , pp. 2943-2950
    • Hideshima, T.1    Chauhan, D.2    Shima, Y.3
  • 24
    • 33644843725 scopus 로고    scopus 로고
    • Oral melphalan and prednisone chemotherapy plus thalidomide compared with melphalan and prednisone alone in elderly patients with multiple myeloma: Randomised controlled trial
    • A. Palumbo, S. Bringhen, and T. Caravita Oral melphalan and prednisone chemotherapy plus thalidomide compared with melphalan and prednisone alone in elderly patients with multiple myeloma: randomised controlled trial Lancet 367 2006 825 831
    • (2006) Lancet , vol.367 , pp. 825-831
    • Palumbo, A.1    Bringhen, S.2    Caravita, T.3
  • 25
    • 34848833957 scopus 로고    scopus 로고
    • Melphalan and prednisone plus thalidomide versus melphalan and prednisone alone or reduced-intensity autologous stem cell transplantation in elderly patients with multiple myeloma (IFM 99-06): A randomised trial
    • T. Facon, J.Y. Mary, and C. Hulin Melphalan and prednisone plus thalidomide versus melphalan and prednisone alone or reduced-intensity autologous stem cell transplantation in elderly patients with multiple myeloma (IFM 99-06): a randomised trial Lancet 370 2007 1209 1218
    • (2007) Lancet , vol.370 , pp. 1209-1218
    • Facon, T.1    Mary, J.Y.2    Hulin, C.3
  • 26
    • 33644831033 scopus 로고    scopus 로고
    • Phase III clinical trial of thalidomide plus dexamethasone compared with dexamethasone alone in newly diagnosed multiple myeloma: A clinical trial coordinated by the Eastern Cooperative Oncology Group
    • S.V. Rajkumar, E. Blood, D. Vesole, R. Fonseca, and P.R. Greipp Phase III clinical trial of thalidomide plus dexamethasone compared with dexamethasone alone in newly diagnosed multiple myeloma: a clinical trial coordinated by the Eastern Cooperative Oncology Group J Clin Oncol 24 2006 431 436
    • (2006) J Clin Oncol , vol.24 , pp. 431-436
    • Rajkumar, S.V.1    Blood, E.2    Vesole, D.3    Fonseca, R.4    Greipp, P.R.5
  • 27
    • 34547106018 scopus 로고    scopus 로고
    • Understanding multiple myeloma pathogenesis in the bone marrow to identify new therapeutic targets
    • T. Hideshima, C. Mitsiades, G. Tonon, P.G. Richardson, and K.C. Anderson Understanding multiple myeloma pathogenesis in the bone marrow to identify new therapeutic targets Nat Rev Cancer 7 8 2007 585 598
    • (2007) Nat Rev Cancer , vol.7 , Issue.8 , pp. 585-598
    • Hideshima, T.1    Mitsiades, C.2    Tonon, G.3    Richardson, P.G.4    Anderson, K.C.5
  • 28
    • 84866021069 scopus 로고    scopus 로고
    • A small molecule inhibitor of ubiquitin-specific protease-7 induces apoptosis in multiple myeloma cells and overcomes bortezomib resistance
    • D. Chauhan, Z. Tian, and B. Nicholson A small molecule inhibitor of ubiquitin-specific protease-7 induces apoptosis in multiple myeloma cells and overcomes bortezomib resistance Cancer Cell 22 3 2012 345 358
    • (2012) Cancer Cell , vol.22 , Issue.3 , pp. 345-358
    • Chauhan, D.1    Tian, Z.2    Nicholson, B.3
  • 29
    • 31544436323 scopus 로고    scopus 로고
    • Antimyeloma activity of heat shock protein-90 inhibition
    • C.S. Mitsiades, N.S. Mitsiades, and C.J. McMullan Antimyeloma activity of heat shock protein-90 inhibition Blood 107 3 2006 1092 1100
    • (2006) Blood , vol.107 , Issue.3 , pp. 1092-1100
    • Mitsiades, C.S.1    Mitsiades, N.S.2    McMullan, C.J.3
  • 30
    • 20344381988 scopus 로고    scopus 로고
    • A clinically relevant SCID-hu in vivo model of human multiple myeloma
    • P. Tassone, P. Neri, and D.R. Carrasco A clinically relevant SCID-hu in vivo model of human multiple myeloma Blood 106 2 2005 713 716
    • (2005) Blood , vol.106 , Issue.2 , pp. 713-716
    • Tassone, P.1    Neri, P.2    Carrasco, D.R.3
  • 31
    • 84864040412 scopus 로고    scopus 로고
    • Drug response in a genetically engineered mouse model of multiple myeloma is predictive of clinical efficacy
    • M. Chesi, G.M. Matthews, and V.M. Garbitt Drug response in a genetically engineered mouse model of multiple myeloma is predictive of clinical efficacy Blood 120 2 2012 376 385
    • (2012) Blood , vol.120 , Issue.2 , pp. 376-385
    • Chesi, M.1    Matthews, G.M.2    Garbitt, V.M.3
  • 32
    • 80052955256 scopus 로고    scopus 로고
    • BET bromodomain inhibition as a therapeutic strategy to target c-Myc
    • J.E. Delmore, G.C. Issa, and M.E. Lemieux BET bromodomain inhibition as a therapeutic strategy to target c-Myc Cell 146 6 2011 904 917
    • (2011) Cell , vol.146 , Issue.6 , pp. 904-917
    • Delmore, J.E.1    Issa, G.C.2    Lemieux, M.E.3
  • 33
    • 84891851776 scopus 로고    scopus 로고
    • CRM1 inhibition induces tumor cell cytotoxicity and impairs osteoclastogenesis in multiple myeloma: Molecular mechanisms and therapeutic implications
    • Apr 16 [Epub ahead of print]
    • Y.T. Tai, Y. Landesman, and C. Acharya CRM1 inhibition induces tumor cell cytotoxicity and impairs osteoclastogenesis in multiple myeloma: molecular mechanisms and therapeutic implications Leukemia 2013 Apr 16 [Epub ahead of print]
    • (2013) Leukemia
    • Tai, Y.T.1    Landesman, Y.2    Acharya, C.3
  • 34
    • 0031906567 scopus 로고    scopus 로고
    • The proteasome inhibitor lactacystin induces apoptosis and sensitizes chemo- and radioresistant human chronic lymphocytic leukaemia lymphocytes to TNF-alpha-initiated apoptosis
    • J. Delic, P. Masdehors, and S. Omura The proteasome inhibitor lactacystin induces apoptosis and sensitizes chemo- and radioresistant human chronic lymphocytic leukaemia lymphocytes to TNF-alpha-initiated apoptosis Br J Cancer 77 7 1998 1103 1107
    • (1998) Br J Cancer , vol.77 , Issue.7 , pp. 1103-1107
    • Delic, J.1    Masdehors, P.2    Omura, S.3
  • 35
    • 0032402111 scopus 로고    scopus 로고
    • Proteasome inhibitors induce apoptosis in glucocorticoid-resistant chronic lymphocytic leukemic lymphocytes
    • J. Chandra, I. Niemer, and J. Gilbreath Proteasome inhibitors induce apoptosis in glucocorticoid-resistant chronic lymphocytic leukemic lymphocytes Blood 92 11 1998 4220 4229
    • (1998) Blood , vol.92 , Issue.11 , pp. 4220-4229
    • Chandra, J.1    Niemer, I.2    Gilbreath, J.3
  • 36
    • 0037441760 scopus 로고    scopus 로고
    • Molecular mechanisms mediating antimyeloma activity of proteasome inhibitor PS-341
    • T. Hideshima, C. Mitsiades, and M. Akiyama Molecular mechanisms mediating antimyeloma activity of proteasome inhibitor PS-341 Blood 101 2003 1530 1534
    • (2003) Blood , vol.101 , pp. 1530-1534
    • Hideshima, T.1    Mitsiades, C.2    Akiyama, M.3
  • 37
    • 0035300479 scopus 로고    scopus 로고
    • The proteasome inhibitor PS-341 inhibits growth, induces apoptosis, and overcomes drug resistance in human multiple myeloma cells
    • T. Hideshima, P. Richardson, and D. Chauhan The proteasome inhibitor PS-341 inhibits growth, induces apoptosis, and overcomes drug resistance in human multiple myeloma cells Cancer Res 61 7 2001 3071 3076
    • (2001) Cancer Res , vol.61 , Issue.7 , pp. 3071-3076
    • Hideshima, T.1    Richardson, P.2    Chauhan, D.3
  • 38
    • 0037111832 scopus 로고    scopus 로고
    • Phase i trial of the proteasome inhibitor PS-341 in patients with refractory hematologic malignancies
    • R.Z. Orlowski, T.E. Stinchcombe, and B.S. Mitchell Phase I trial of the proteasome inhibitor PS-341 in patients with refractory hematologic malignancies J Clin Oncol 20 22 2002 4420 4427
    • (2002) J Clin Oncol , vol.20 , Issue.22 , pp. 4420-4427
    • Orlowski, R.Z.1    Stinchcombe, T.E.2    Mitchell, B.S.3
  • 39
    • 0037973279 scopus 로고    scopus 로고
    • A phase 2 study of bortezomib in relapsed, refractory myeloma
    • P.G. Richardson, B. Barlogie, and J. Berenson A phase 2 study of bortezomib in relapsed, refractory myeloma N Engl J Med 348 26 2003 2609 2617
    • (2003) N Engl J Med , vol.348 , Issue.26 , pp. 2609-2617
    • Richardson, P.G.1    Barlogie, B.2    Berenson, J.3
  • 40
    • 5644250621 scopus 로고    scopus 로고
    • A phase 2 study of two doses of bortezomib in relapsed or refractory myeloma
    • S. Jagannath, B. Barlogie, and J. Berenson A phase 2 study of two doses of bortezomib in relapsed or refractory myeloma Br J Haematol 127 2 2004 165 172
    • (2004) Br J Haematol , vol.127 , Issue.2 , pp. 165-172
    • Jagannath, S.1    Barlogie, B.2    Berenson, J.3
  • 41
    • 20444433230 scopus 로고    scopus 로고
    • Bortezomib or high-dose dexamethasone for relapsed multiple myeloma
    • P.G. Richardson, P. Sonneveld, and M.W. Schuster Bortezomib or high-dose dexamethasone for relapsed multiple myeloma N Engl J Med 352 24 2005 2487 2498
    • (2005) N Engl J Med , vol.352 , Issue.24 , pp. 2487-2498
    • Richardson, P.G.1    Sonneveld, P.2    Schuster, M.W.3
  • 42
    • 0041524053 scopus 로고    scopus 로고
    • A transcriptional progression model for head and neck cancer
    • P.K. Ha, N.E. Benoit, and R. Yochem A transcriptional progression model for head and neck cancer Clin Cancer Res 9 8 2003 3058 3064
    • (2003) Clin Cancer Res , vol.9 , Issue.8 , pp. 3058-3064
    • Ha, P.K.1    Benoit, N.E.2    Yochem, R.3
  • 43
    • 0037443551 scopus 로고    scopus 로고
    • The proteasome inhibitor PS-341 potentiates sensitivity of multiple myeloma cells to conventional chemotherapeutic agents: Therapeutic applications
    • N. Mitsiades, C.S. Mitsiades, and P.G. Richardson The proteasome inhibitor PS-341 potentiates sensitivity of multiple myeloma cells to conventional chemotherapeutic agents: therapeutic applications Blood 101 6 2003 2377 2380
    • (2003) Blood , vol.101 , Issue.6 , pp. 2377-2380
    • Mitsiades, N.1    Mitsiades, C.S.2    Richardson, P.G.3
  • 44
    • 0242496212 scopus 로고    scopus 로고
    • Molecular sequelae of proteasome inhibition in human multiple myeloma cells
    • N. Mitsiades, C.S. Mitsiades, and V. Poulaki Molecular sequelae of proteasome inhibition in human multiple myeloma cells Proc Natl Acad Sci U S A 99 22 2002 14374 14379
    • (2002) Proc Natl Acad Sci U S A , vol.99 , Issue.22 , pp. 14374-14379
    • Mitsiades, N.1    Mitsiades, C.S.2    Poulaki, V.3
  • 45
    • 78049488759 scopus 로고    scopus 로고
    • Bortezomib plus dexamethasone is superior to vincristine plus doxorubicin plus dexamethasone as induction treatment prior to autologous stem-cell transplantation in newly diagnosed multiple myeloma: Results of the IFM 2005-01 phase III trial
    • J.L. Harousseau, M. Attal, and H. Avet-Loiseau Bortezomib plus dexamethasone is superior to vincristine plus doxorubicin plus dexamethasone as induction treatment prior to autologous stem-cell transplantation in newly diagnosed multiple myeloma: results of the IFM 2005-01 phase III trial J Clin Oncol 28 30 2010 4621 4629
    • (2010) J Clin Oncol , vol.28 , Issue.30 , pp. 4621-4629
    • Harousseau, J.L.1    Attal, M.2    Avet-Loiseau, H.3
  • 46
    • 34548539381 scopus 로고    scopus 로고
    • Randomized phase III study of pegylated liposomal doxorubicin plus bortezomib compared with bortezomib alone in relapsed or refractory multiple myeloma: Combination therapy improves time to progression
    • R.Z. Orlowski, A. Nagler, and P. Sonneveld Randomized phase III study of pegylated liposomal doxorubicin plus bortezomib compared with bortezomib alone in relapsed or refractory multiple myeloma: combination therapy improves time to progression J Clin Oncol 25 25 2007 3892 3901
    • (2007) J Clin Oncol , vol.25 , Issue.25 , pp. 3892-3901
    • Orlowski, R.Z.1    Nagler, A.2    Sonneveld, P.3
  • 47
    • 50449086728 scopus 로고    scopus 로고
    • Bortezomib plus melphalan and prednisone for initial treatment of multiple myeloma
    • J.F. San Miguel, R. Schlag, and N.K. Khuageva Bortezomib plus melphalan and prednisone for initial treatment of multiple myeloma N Engl J Med 359 9 2008 906 917
    • (2008) N Engl J Med , vol.359 , Issue.9 , pp. 906-917
    • San Miguel, J.F.1    Schlag, R.2    Khuageva, N.K.3
  • 48
    • 78650303860 scopus 로고    scopus 로고
    • Bortezomib with thalidomide plus dexamethasone compared with thalidomide plus dexamethasone as induction therapy before, and consolidation therapy after, double autologous stem-cell transplantation in newly diagnosed multiple myeloma: A randomised phase 3 study
    • M. Cavo, P. Tacchetti, and F. Patriarca Bortezomib with thalidomide plus dexamethasone compared with thalidomide plus dexamethasone as induction therapy before, and consolidation therapy after, double autologous stem-cell transplantation in newly diagnosed multiple myeloma: a randomised phase 3 study Lancet 376 9758 2010 2075 2085
    • (2010) Lancet , vol.376 , Issue.9758 , pp. 2075-2085
    • Cavo, M.1    Tacchetti, P.2    Patriarca, F.3
  • 49
    • 84865444078 scopus 로고    scopus 로고
    • Superiority of bortezomib, thalidomide, and dexamethasone (VTD) as induction pretransplantation therapy in multiple myeloma: A randomized phase 3 PETHEMA/GEM study
    • L. Rosinol, A. Oriol, and A.I. Teruel Superiority of bortezomib, thalidomide, and dexamethasone (VTD) as induction pretransplantation therapy in multiple myeloma: a randomized phase 3 PETHEMA/GEM study Blood 120 8 2012 1589 1596
    • (2012) Blood , vol.120 , Issue.8 , pp. 1589-1596
    • Rosinol, L.1    Oriol, A.2    Teruel, A.I.3
  • 50
    • 84865171981 scopus 로고    scopus 로고
    • Bortezomib induction and maintenance treatment in patients with newly diagnosed multiple myeloma: Results of the randomized phase III HOVON-65/ GMMG-HD4 trial
    • P. Sonneveld, I.G. Schmidt-Wolf, and B. van der Holt Bortezomib induction and maintenance treatment in patients with newly diagnosed multiple myeloma: results of the randomized phase III HOVON-65/ GMMG-HD4 trial J Clin Oncol 30 24 2012 2946 2955
    • (2012) J Clin Oncol , vol.30 , Issue.24 , pp. 2946-2955
    • Sonneveld, P.1    Schmidt-Wolf, I.G.2    Van Der Holt, B.3
  • 51
    • 73349115580 scopus 로고    scopus 로고
    • Multicenter, phase I, dose-escalation trial of lenalidomide plus bortezomib for relapsed and relapsed/refractory multiple myeloma
    • P.G. Richardson, E. Weller, and S. Jagannath Multicenter, phase I, dose-escalation trial of lenalidomide plus bortezomib for relapsed and relapsed/refractory multiple myeloma J Clin Oncol 27 34 2009 5713 5719
    • (2009) J Clin Oncol , vol.27 , Issue.34 , pp. 5713-5719
    • Richardson, P.G.1    Weller, E.2    Jagannath, S.3
  • 52
    • 77954618168 scopus 로고    scopus 로고
    • Lenalidomide, bortezomib, and dexamethasone combination therapy in patients with newly diagnosed multiple myeloma
    • P.G. Richardson, E. Weller, and S. Lonial Lenalidomide, bortezomib, and dexamethasone combination therapy in patients with newly diagnosed multiple myeloma Blood 116 5 2010 679 686
    • (2010) Blood , vol.116 , Issue.5 , pp. 679-686
    • Richardson, P.G.1    Weller, E.2    Lonial, S.3
  • 53
    • 54249122860 scopus 로고    scopus 로고
    • Phase I-II trial of bortezomib plus oral cyclophosphamide and prednisone in relapsed and refractory multiple myeloma
    • D.E. Reece, G.P. Rodriguez, and C. Chen Phase I-II trial of bortezomib plus oral cyclophosphamide and prednisone in relapsed and refractory multiple myeloma J Clin Oncol 26 29 2008 4777 4783
    • (2008) J Clin Oncol , vol.26 , Issue.29 , pp. 4777-4783
    • Reece, D.E.1    Rodriguez, G.P.2    Chen, C.3
  • 54
    • 77954660886 scopus 로고    scopus 로고
    • Bortezomib, dexamethasone, cyclophosphamide and lenalidomide combination for newly diagnosed multiple myeloma: Phase 1 results from the multicenter EVOLUTION study
    • S.K. Kumar, I. Flinn, and S.J. Noga Bortezomib, dexamethasone, cyclophosphamide and lenalidomide combination for newly diagnosed multiple myeloma: phase 1 results from the multicenter EVOLUTION study Leukemia 24 7 2010 1350 1356
    • (2010) Leukemia , vol.24 , Issue.7 , pp. 1350-1356
    • Kumar, S.K.1    Flinn, I.2    Noga, S.J.3
  • 56
    • 74049142026 scopus 로고    scopus 로고
    • The use of novel agents in the treatment of relapsed and refractory multiple myeloma
    • J.P. Laubach, A. Mahindra, and C.S. Mitsiades The use of novel agents in the treatment of relapsed and refractory multiple myeloma Leukemia 23 12 2009 2222 2232
    • (2009) Leukemia , vol.23 , Issue.12 , pp. 2222-2232
    • Laubach, J.P.1    Mahindra, A.2    Mitsiades, C.S.3
  • 57
    • 79952720734 scopus 로고    scopus 로고
    • Treatment options for relapsed and refractory multiple myeloma
    • S. Lonial, C.S. Mitsiades, and P.G. Richardson Treatment options for relapsed and refractory multiple myeloma Clin Cancer Res 17 6 2011 1264 1277
    • (2011) Clin Cancer Res , vol.17 , Issue.6 , pp. 1264-1277
    • Lonial, S.1    Mitsiades, C.S.2    Richardson, P.G.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.