Diagnosing oesophagitis in children: How discriminative is histology?

Acta Gastro-Enterologica Belgica

Volumn 76, Issue 3, 2013, Pages 300-305

  Karabulut, Y Y ^a   Savas B ^a   Kansu, A ^a   Kursun N ^a   Ensari, A ^a  

^a ANKARA UNIVERSITY   (Turkey)

Author keywords

Eosinophilic oesophagitis; Histologic features; Reflux oesophagitis

Indexed keywords

ARTICLE; BASAL CELL HYPERPLASIA; CELL HYPERPLASIA; CHILD; CHILDHOOD DISEASE; CONTROLLED STUDY; EOSINOPHIL; EOSINOPHIL COUNT; EOSINOPHILIC ESOPHAGITIS; ESOPHAGUS BIOPSY; FEMALE; HISTOLOGY; HUMAN; LYMPHOCYTE; LYMPHOCYTE COUNT; MAJOR CLINICAL STUDY; MALE; NEUTROPHIL; NEUTROPHIL COUNT; REFLUX ESOPHAGITIS; SCHOOL CHILD;

EID: 84886856624     PISSN: 00015644     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (32)

1. NOFFSINGER A.E. Update on eosophagitis. Controversial and underdiag-nosed causes. Arch. Path. Lab. Med., 2009, 133: 1987-1095.
2. ENSARI A. Eosinophilic oesophagitis versus reflux oesophagitis. Acta Gastro-Enterologica Belgica, Vol. LXXIV, April-June 2011.
3. ALLENDE D.S., YERIAN L.M. Diagnosing gastroesophageal reflux disease. The pathologist's perspective. Adv. Anat. Pathol., 2009, 16: 161-165.
4. DENT J., El-Serag H.B., M. A. WALLANDER, JOHANSSON S. Epidemiology of gastro-oesophageal reflux disease: a systematic review. Gut, 2005, 54 (5): 710-717.
5. VOUTILAINEN M., SIPPONEN P., MECKLIN J.P., JUHOLA M., FARKKILA M. Gastroesophageal reflux disease: prevalence, clinical, endoscopic and histopathologic findings in 1128 consecutive patients referred for endoscopy due to dyspeptic and reflux symptoms. Digestion, 2000, 61 (1): 6-13.
6. nd. Histological consequences of gastroesophageal reflux in man. Gastroenterology, 1970, 58 (2): 163-174.
7. FURUTA G.T., LIACOURAS C.A., COLLINS M.H. et al. Eosinophilic esophagitis in children and adults: a systematic review and consensus recommendations for diagnosis and treatment. Gastroenterology, 2007, 133 (4): 1342-1363.
8. GENEVAY M., Ubbia-Brandt L., ROUGEMONT A.-L. Do Eosinophil Numbers Differentiate Eosinophilic Esophagitis from Gastroesophageal Reflux Disease? Archives of Pathology & Laboratory Medicine, June 2010, Vol. 134, No. 6, pp. 815-825.
9. LIACOURAS C.A., SPERGEL J.M., RUCHELLI E. Eosinophilic esophagitis: a 10-year experience in 381 children. Clin. Gastroenterol. Hepatol., 2005, 3 (12): 1198-1206.
10. TAKUBO K., HONMA N., ARYAL G., SAWABE M., ARAI T., Tanaka Y. et al. Is there a set of histologic changes that are i{dotless}nvariably reflux associated? Arch. Pathol. Lab. Med., 2005, 129: 159-163.
11. ROTHENBERG M.E., MISHRA A., COLLINS M.H., PUTNAM P.E. Pathogenesis and clinical features of eosinophilic oesophagitis. J. Allergy Clin. Immunol., 2001, 108: 891-894.
12. RODRIGO S., ABBOUT G., OH D. High intraepithelial eosinophile counts in oesophageal squamous epithelium are not spesific for eosinophilic oesophagitis for adults. Am. J. Gastroenterol., 2008, 103: 435-442.
13. KIKENDALL JW. Pill-induced eosophagitis. Gastroenterol. Hepatol. (NY), 2007 Apr, 3 (4): 275-276.
14. CHEUNG K.M., OLIVER M.R., CAMERON D.J. Esophageal eosinophilia in children with disphagia. J. Ped. Gastroenterol. Nutr., 2003, 37: 498-503.
15. SHUB M.D., ULSHEN M.H., HARGROVE C.B., SIEGAL G.P., GROBEN P.A., ASKIN F.B. Esophagitis: a frequent consequence of gastro-esophageal reflux in infancy. J. Pediatr., 1985, 107 (6): 881-884.
16. TUMMALA V., BARWICK K.W., SONTAG S.J., VLAHCEVIC R.Z., MCCALLUM R.W. The significance of intraepithelial eosinophils in the histologic diagnosis of gastroesophageal reflux. Am. J. Clin. Pathol., 1987, 87 (1): 43-48.
17. RUCHELLI E., WENNER W., VOYTEK T., BROWN K., LIACOURAS C. Severity of esophageal eosinophilia predicts response to conventional gastroesophageal reflux therapy. Pediatr. Dev. Pathol., 1999, 2 (1): 15-18.
18. CHADWICK L.M., KURINCZUK J. J., HALLAM L.A., BRENNAN B.A., FORBES D. Clinical and endoscopic predictors of histological oesophagitis in infants. J. Paediatr. Child Health, 1997, 33 (5): 388-393.
19. ZENTILIN P., SAVARINO V., MASTRACCI L. Reassessment of the diagnostic value of histology in patients with GERD, using multiple biopsy sites and an appropriate control group. Am. J. Gastroenterol., 2005, 100 (10): 2299-2306.
20. SABRI M.T., HUSSAIN S.Z., SHALABY T.M., ORENSTEIN S.R. Morphometric histology for infant gastroesophageal reflux disease: evaluation of reliability in 497 esophageal biopsies. J. Pediatr. Gastroenterol. Nutr., 2007, 44 (1): 27-34.
21. STEINER S.J., KERNEK K.M., FITZGERALD J.F. Severity of basal cell hyperplasia differs in reflux versus eosinophilic esophagitis. J. Pediatr. Gastroenterol. Nutr., 2006, 42 (5): 506-509.
22. TOBEY N.A., CARSON J.L., ALKIEK R.A., ORLANDO R.C. Dilated intercellular spaces: a morphological feature of acid reflux - damaged human esophageal epithelium. Gastroenterology, 1996, 111 (5): 1200-1205.
23. ORLANDO R.C. Pathogenesis of reflux esophagitis and Barrett's esophagus. Med. Clin. North Am., 2005, 89 (2): 219-241, vii.
24. ANTONIOLI D.A., FURUTA G.T. Allergic eosinophilic esophagitis: a primer for pathologists. Semin. Diagn. Pathol., 2005, 22 (4): 266-272.
25. STEINER S.J., KERK K.M., FITZGERAL J.F. Severity of basal cell hyperplasia differs in reflux versus eosinophilic oesophagitis. JPGN, 2006, 42: 506-509.
26. Ireland-Jenkin K., WU X., HEINE R.G., CAMERON D.J., CATTOSMITH A.G., CHOW C.W. Oesophagitis in children: reflux or allergy? Pathology, 2008, 40 (2): 188-195.
27. MUELLER S., AIGNER T., NEUREITER D., STOLTE M. Eosinophil infiltration and degranulation in oesophageal mucosa from adult patients with eosinophilic oesophagitis: a retrospective and comparative study on pathological biopsy. J. Clin. Pathol., 2006, 59 (11): 1175-1180.
28. ALLENDE D.S., YERIAN L.M. Diagnosing gastroesophageal reflux disease. The pathologist's perspective. Adv. Anat. Pathol., 2009, 129: 159-163.
29. BASSERI B., LEVY M., WANG H.L., SHAYE O.A., PIMENTEL M., SOFFER E.E., CONKLIN J.L. Redefining the role of lymphocytes in gastro-esophageal reflux disease and eosinophilic esophagitis. Diseases of the Esophagus, 2010, 23: 368-376.
30. AMY E., NOFFSINGER M.D. Update on oesophagitis. Arch. Pathol. Lab. Med., 2009, 133: 1087-1095.
31. CHANG F., ANDERSON S. Clinical and pathological features of eosinophilic oesophagitis: a review. Pathology, 2008, 40: 3-8.
32. RAVELLI A.M., TOBANELLI P., VILLANACCI V. et al. Dilated inter-cellular spaces (DIS): a novel morphological approach to gastroesophageal reflux disease (GERD). J. Pediatr. Gastroenterol. Nutr., 2000, 31: 205-209.