X-ray-verified fractures are associated with finite element analysis-derived bone strength and trabecular microstructure in young adult men

Journal of Bone and Mineral Research

Volumn 28, Issue 11, 2013, Pages 2305-2316

  Rudäng, Robert ^a,b   Darelid, Anna ^a,b   Nilsson, Martin ^a,b   Mellström, Dan ^a,b   Ohlsson, Claes ^b   Lorentzon, Mattias ^a,b  

^a UNIVERSITY OF GOTHENBURG   (Sweden)

^b UNIVERSITY OF GOTHENBURG   (Sweden)

Author keywords

FRACTURE; HR pQCT; TRABECULAR MICROSTRUCTURE

Indexed keywords

ADULT; ARTICLE; BONE DENSITY; BONE MASS; BONE RADIOGRAPHY; BONE STRENGTH; BONE STRUCTURE; COMPUTER PROGRAM; CORTICAL THICKNESS (BONE); CROSS-SECTIONAL STUDY; DUAL ENERGY X RAY ABSORPTIOMETRY; FEMALE; FINITE ELEMENT ANALYSIS; HIGH RESOLUTION COMPUTER TOMOGRAPHY; HUMAN; MAJOR CLINICAL STUDY; MALE; POPULATION RESEARCH; POROSITY; PREVALENCE; RADIUS FRACTURE; TIBIA FRACTURE; TRABECULAR BONE;

FRACTURE; HR-PQCT; TRABECULAR MICROSTRUCTURE;

ANTHROPOMETRY; BIOMECHANICAL PHENOMENA; BONE AND BONES; BONE DENSITY; CONFIDENCE INTERVALS; FINITE ELEMENT ANALYSIS; FRACTURES, BONE; HUMANS; MALE; ODDS RATIO; PREVALENCE; REPRODUCIBILITY OF RESULTS; WEIGHT-BEARING; X-RAYS; YOUNG ADULT;

EID: 84886836653     PISSN: 08840431     EISSN: 15234681     Source Type: Journal    
DOI: 10.1002/jbmr.1974     Document Type: Article

References (41)

1. Ferrari SL, Chevalley T, Bonjour JP, Rizzoli R., Childhood fractures are associated with decreased bone mass gain during puberty: an early marker of persistent bone fragility?. J Bone Miner Res. Apr 2006; 21 (4): 501-7.
2. Buttazzoni C, Rosengren EB, Tveit M, Landin L, Nilsson JA, Karlsson KM., Does a childhood fracture predict low bone mass in young adulthood? A 27-year prospective controlled study. J Bone Miner Res. Feb 2013; 28 (2): 351-9.
3. Hernandez CJ, Beaupre GS, Carter DR., A theoretical analysis of the relative influences of peak BMD, age-related bone loss and menopause on the development of osteoporosis. Osteoporos Int. Oct 2003; 14 (10): 843-7.
4. Hui SL, Slemenda CW, Johnston CC Jr., The contribution of bone loss to postmenopausal osteoporosis. Osteoporos Int. Oct 1990; 1 (1): 30-4.
5. Khosla S, Melton LJ 3rd, Dekutoski MB, Achenbach SJ, Oberg AL, Riggs BL., Incidence of childhood distal forearm fractures over 30 years: a population-based study. JAMA. Sep 17 2003; 290 (11): 1479-85.
6. Clark EM, Ness AR, Tobias JH., Bone fragility contributes to the risk of fracture in children, even after moderate and severe trauma. J Bone Miner Res. Feb 2008; 23 (2): 173-9.
7. Clark EM, Tobias JH, Ness AR., Association between bone density and fractures in children: a systematic review and meta-analysis. Pediatrics. Feb 2006; 117 (2): e291-7.
8. Goulding A, Cannan R, Williams SM, Gold EJ, Taylor RW, Lewis-Barned NJ., Bone mineral density in girls with forearm fractures. J Bone Miner Res. Jan 1998; 13 (1): 143-8.
9. Goulding A, Jones IE, Taylor RW, Williams SM, Manning PJ., Bone mineral density and body composition in boys with distal forearm fractures: a dual-energy x-ray absorptiometry study. J Pediatr. Oct 2001; 139 (4): 509-15.
10. Darelid A, Ohlsson C, Rudang R, Kindblom JM, Mellstrom D, Lorentzon M., Trabecular volumetric bone mineral density is associated with previous fracture during childhood and adolescence in males: the GOOD study. J Bone Miner Res. Mar 2010; 25 (3): 537-44.
11. Ohlsson C, Darelid A, Nilsson M, Melin J, Mellstrom D, Lorentzon M., Cortical consolidation due to increased mineralization and endosteal contraction in young adult men: a five-year longitudinal study. J Clin Endocrinol Metab. Jul 2011; 96 (7): 2262-9.
12. Taes Y, Lapauw B, Griet V, De Bacquer D, Goemaere S, Zmierczak H, Kaufman JM., Prevalent fractures are related to cortical bone geometry in young healthy men at age of peak bone mass. J Bone Miner Res. Jun 2010; 25 (6): 1433-40.
13. Chevalley T, Bonjour JP, van Rietbergen B, Ferrari S, Rizzoli R., Fractures during childhood and adolescence in healthy boys: relation with bone mass, microstructure, and strength. J Clin Endocrinol Metab. Oct 2011; 96 (10): 3134-42.
14. Farr JN, Tomas R, Chen Z, Lisse JR, Lohman TG, Going SB., Lower trabecular volumetric BMD at metaphyseal regions of weight-bearing bones is associated with prior fracture in young girls. J Bone Miner Res. Feb 2011; 26 (2): 380-7.
15. Chevalley T, Bonjour JP, van Rietbergen B, Rizzoli R, Ferrari S., Fractures in healthy females followed from childhood to early adulthood are associated with later menarcheal age and with impaired bone microstructure at peak bone mass. J Clin Endocrinol Metab. Nov 2012; 97 (11): 4174-81.
16. Laib A, Hauselmann HJ, Ruegsegger P., In vivo high resolution 3D-QCT of the human forearm. Technol Health Care. Dec 1998; 6 (5-6): 329-37.
17. Majumdar S, Genant HK., Assessment of trabecular structure using high resolution magnetic resonance imaging. Stud Health Technol Inform. 1997; 40: 81-96.
18. Burghardt AJ, Kazakia GJ, Ramachandran S, Link TM, Majumdar S., Age- and gender-related differences in the geometric properties and biomechanical significance of intracortical porosity in the distal radius and tibia. J Bone Miner Res. May 2010; 25 (5): 983-93.
19. Nishiyama KK, Macdonald HM, Buie HR, Hanley DA, Boyd SK., Postmenopausal women with osteopenia have higher cortical porosity and thinner cortices at the distal radius and tibia than women with normal aBMD: an in vivo HR-pQCT study. J Bone Miner Res. Apr 2010; 25 (4): 882-90.
20. Pistoia W, van Rietbergen B, Lochmuller EM, Lill CA, Eckstein F, Ruegsegger P., Estimation of distal radius failure load with micro-finite element analysis models based on three-dimensional peripheral quantitative computed tomography images. Bone. Jun 2002; 30 (6): 842-8.
21. Pistoia W, van Rietbergen B, Lochmuller EM, Lill CA, Eckstein F, Ruegsegger P., Image-based micro-finite-element modeling for improved distal radius strength diagnosis: moving from bench to bedside. J Clin Densitom. Summer. 2004; 7 (2): 153-60.
22. Lorentzon M, Mellstrom D, Ohlsson C., Age of attainment of peak bone mass is site specific in Swedish men-The GOOD study. J Bone Miner Res. Jul 2005; 20 (7): 1223-7.
23. Kemper HC, Bakker I, Twisk JW, van Mechelen W., Validation of a physical activity questionnaire to measure the effect of mechanical strain on bone mass. Bone. May 2002; 30 (5): 799-804.
24. The National Food Administration Food Database (Sweden). National Food Administration, Uppsala, Sweden; 2012. Cited 2012 November 7. Available from: http://www.slv.se/en-gb/Group1/Food-and-Nutrition/The-Food-Database/.
25. Nevitt MC, Cummings SR, Browner WS, Seeley DG, Cauley JA, Vogt TM, Black DM., The accuracy of self-report of fractures in elderly women: evidence from a prospective study. Am J Epidemiol. Mar 1 1992; 135 (5): 490-9.
26. MacNeil JA, Boyd SK., Load distribution and the predictive power of morphological indices in the distal radius and tibia by high resolution peripheral quantitative computed tomography. Bone. Jul 2007; 41 (1): 129-37.
27. Burghardt AJ, Buie HR, Laib A, Majumdar S, Boyd SK., Reproducibility of direct quantitative measures of cortical bone microarchitecture of the distal radius and tibia by HR-pQCT. Bone. Sep 2010; 47 (3): 519-28.
28. van Rietbergen B, Weinans H, Huiskes R, Odgaard A., A new method to determine trabecular bone elastic properties and loading using micromechanical finite-element models. J Biomechan. Jan 1995; 28 (1): 69-81.
29. Chiu J, Robinovitch SN., Prediction of upper extremity impact forces during falls on the outstretched hand. J Biomech. Dec 1998; 31 (12): 1169-76.
30. Wang Q, Wang XF, Iuliano-Burns S, Ghasem-Zadeh A, Zebaze R, Seeman E., Rapid growth produces transient cortical weakness: a risk factor for metaphyseal fractures during puberty. J Bone Miner Res. Jul 2010; 25 (7): 1521-6.
31. Kirmani S, Christen D, van Lenthe GH, Fischer PR, Bouxsein ML, McCready LK, Melton LJ 3rd, Riggs BL, Amin S, Muller R, Khosla S., Bone structure at the distal radius during adolescent growth. J Bone Miner Res. Jun 2009; 24 (6): 1033-42.
32. Pritchett JW., Growth plate activity in the upper extremity. Clin Orthopaed Rel Res. Jul 1991; (268): 235-42.
33. Pritchett JW., Longitudinal growth and growth-plate activity in the lower extremity. Clin Orthopaed Rel Res. Feb 1992; (275): 274-9.
34. Yeni YN, Brown CU, Wang Z, Norman TL., The influence of bone morphology on fracture toughness of the human femur and tibia. Bone. Nov 1997; 21 (5): 453-9.
35. Bailey DA, Wedge JH, McCulloch RG, Martin AD, Bernhardson SC., Epidemiology of fractures of the distal end of the radius in children as associated with growth. J Bone Joint Surg. American volume. Sep 1989; 71 (8): 1225-31.
36. Landin LA., Fracture patterns in children. Analysis of 8,682 fractures with special reference to incidence, etiology and secular changes in a Swedish urban population 1950-1979. Acta Orthop Scand Suppl. 1983; 202: 1-109.
37. Bonjour JP, Theintz G, Law F, Slosman D, Rizzoli R., Peak bone mass. Osteoporos Int. 1994; 4 (Suppl 1): 7-13.
38. Macneil JA, Boyd SK., Bone strength at the distal radius can be estimated from high-resolution peripheral quantitative computed tomography and the finite element method. Bone. Jun 2008; 42 (6): 1203-13.
39. Mueller TL, Christen D, Sandercott S, Boyd SK, van Rietbergen B, Eckstein F, Lochmuller EM, Muller R, van Lenthe GH., Computational finite element bone mechanics accurately predicts mechanical competence in the human radius of an elderly population. Bone. Jun 1 2011; 48 (6): 1232-8.
40. Mackey DC, Lui LY, Cawthon PM, Bauer DC, Nevitt MC, Cauley JA, Hillier TA, Lewis CE, Barrett-Connor E, Cummings SR., High-trauma fractures and low bone mineral density in older women and men. JAMA. Nov 28 2007; 298 (20): 2381-8.
41. Sanders KM, Pasco JA, Ugoni AM, Nicholson GC, Seeman E, Martin TJ, Skoric B, Panahi S, Kotowicz MA., The exclusion of high trauma fractures may underestimate the prevalence of bone fragility fractures in the community: the Geelong Osteoporosis Study. J Bone Miner Res. Aug 1998; 13 (8): 1337-42.