Lower trabecular volumetric BMD at metaphyseal regions of weight-bearing bones is associated with prior fracture in young girls

Journal of Bone and Mineral Research

Volumn 26, Issue 2, 2011, Pages 380-387

  Farr, Joshua N ^a   Tomás, Rita ^a,b   Chen, Zhao ^a   Lisse, Jeffrey R ^c   Lohman, Timothy G ^a   Going, Scott B ^a  

^a UNIVERSITY OF ARIZONA   (United States)

^b HOSPITAL CURRY CABRAL   (Portugal)

^c UNIVERSITY OF ARIZONA COLLEGE OF MEDICINE   (United States)

Author keywords

BONE GEOMETRY; FRACTURE; PERIPHERAL QUANTITATIVE COMPUTED TOMOGRAPHY (PQCT); VOLUMETRIC BONE MINERAL DENSITY (VBMD); YOUTH

Indexed keywords

ADOLESCENT; ARTICLE; BODY MASS; BONE DENSITY; BONE FRAGILITY; BONE MINERAL; CHILD; DIAPHYSIS; DISEASE ASSOCIATION; ETHNICITY; FEMALE; FEMUR; FRACTURE; HUMAN; LEG LENGTH; LONG BONE; LUMBAR SPINE; MAJOR CLINICAL STUDY; METAPHYSIS; PERIOSTEUM; PHYSICAL ACTIVITY; PREVALENCE; TIBIA; TRABECULAR BONE; WEIGHT BEARING;

ABSORPTIOMETRY, PHOTON; ADOLESCENT; ANTHROPOMETRY; BODY COMPOSITION; BONE AND BONES; BONE DENSITY; CHILD; FEMALE; FRACTURES, BONE; HUMANS; MODELS, STATISTICAL; MOTOR ACTIVITY; MUSCULOSKELETAL PHYSIOLOGICAL PHENOMENA; TOMOGRAPHY, X-RAY COMPUTED;

EID: 79251526880     PISSN: 08840431     EISSN: None     Source Type: Journal    
DOI: 10.1002/jbmr.218     Document Type: Article

References (49)

1. Landin LA., Fracture patterns in children: analysis of 8,682 fractures with special reference to incidence, etiology and secular changes in a Swedish urban population 1950- 1979. Acta Orthop Scand Suppl. 1983; 202: 1-109.
2. Bailey DA, Wedge JH, McCulloch RG, Martin AD, Bernhardson SC., Epidemiology of fractures of the distal end of the radius in children as associated with growth. J Bone Joint Surg Am. 1989; 71: 1225-1231.
3. Tiderius CJ, Landin L, Duppe H., Decreasing incidence of fractures in children: an epidemiological analysis of 1673 fractures in Malmo, Sweden, 1993- 1994. Acta Orthop Scand. 1999; 70: 622-626.
4. Cooper C, Dennison EM, Leufkens HG, Bishop N, van Staa TP., Epidemiology of childhood fractures in Britain: a study using the general practice research database. J Bone Miner Res. 2004; 19: 1976-1981.
5. Goulding A, Jones IE, Taylor RW, Manning PJ, Williams SM., More broken bones: a 4-year double cohort study of young girls with and without distal forearm fractures. J Bone Miner Res. 2000; 15: 2011-2018.
6. Goulding A., Risk factors for fractures in normally active children and adolescents. In:, Daly RM, Petit MA, eds. The Role of Physical Activity and Nutrition during Growth. Basel: Karger Publishing, pp 102-120. 2007.
7. Khosla S, Melton LJ 3rd, Dekutoski MB, et al. Incidence of childhood distal forearm fractures over 30 years: a population-based study. JAMA. 2003; 290: 1479-1485.
8. Chan GM, Hess M, Hollis J, Book LS., Bone mineral status in childhood accidental fractures. Am J Dis Child. 1984; 138: 569-570.
9. Goulding A, Cannan R, Williams SM, et al. Bone mineral density in girls with forearm fractures. J Bone Miner Res. 1998; 13: 143-148.
10. Landin LA, Nilsson BE., BMC in children with fractures. Orthop Relat Res. 1983; 178: 292-296.
11. Ma D, Jones G., The association between bone mineral density, metacarpal morphometry, and upper limb fractures in children: a population-based case-control study. J Clin Endocrinol Metab. 2003; 88: 1486-1491.
12. Suuriniemi M, Mahonen A, Kovanen V, Alen M, Cheng S., Relation of PvuII site polymorphism in the COL1A2 gene to the risk of fractures in prepubertal Finnish girls. Physiol Genomics. 2003; 14: 217-224.
13. Ferrari SL, Chevalley T, Bonjour JP, Rizzoli R., Childhood fractures are associated with decreased bone mass gain during puberty: an early marker of persistent bone fragility ? J Bone Miner Res. 2006; 21: 501-507.
14. Clark EM, Tobias JH, Ness AR., Association between bone density and fractures in children: a systematic review and meta-analysis. Pediatrics. 2006; 117: e291-297.
15. Jones IE, Taylor RW, Williams SM, Manning PJ, Goulding A., Four-year gain in bone mineral in girls with and without past forearm fractures: a DXA study. J Bone Miner Res. 2002; 17: 1065-1072.
16. Cheng S, Xu L, Nicholson PH, et al. Low volumetric BMD is linked to upper-limb fracture in pubertal girls and persists into adulthood: a seven-year cohort study. Bone. 2009; 45: 480-486.
17. Wang Q, Cheng S, Alen M, Seeman E., Bones structural diversity in adult females is established before puberty. J Clin Endocrinol Metab. 2009; 94: 1555-1561.
18. Darelid A, Ohlsson C, Rudang R, et al. Trabecular volumetric bone mineral density is associated with previous fracture during childhood and adolescence in males: The GOOD Study. J Bone Miner Res. 2010; 25: 537-544.
19. Parfitt AM., The two faces of growth: benefits and risks to bone integrity. Osteoporos Int. 1994; 4: 382-398.
20. Rauch F, Neu C, Manz F, Schoenau E., The development of metaphyseal cortex-implications for distal radius fractures during growth. J Bone Miner Res. 2001; 16: 1547-1555.
21. Skaggs DL, Loro ML, Pitukcheewanont P, Tolo V, Gilsanz V., Increased body weight and decreased radial cross-sectional dimensions in girls with forearm fractures. J Bone Miner Res. 2001; 16: 1337-1342.
22. Farr JN, Chen Z, Lisse JR, Lohman TG, Going SB., Relationship of total body fat mass to weight-bearing bone volumetric density, geometry, and strength in young girls. Bone. 2010; 46: 977-984.
23. American Academy of Pediatrics. Medical conditions affecting sports participation. Pediatrics. 2001; 107: 1205-1209.
24. Farr JN, Lee VR, Blew RM, Lohman TG, Going SB., Quantifying bone-relevant activity and its relation to bone strength in girls. Med Sci Sports Exerc;. [Epub ahead of print]; 2010; DOI 10.1249/MSS.0b013e3181eeb2f2.
25. Farr JN, Blew RM, Lee VR, Lohman TG, Going SB., Associations of physical activity duration, frequency, and load with volumetric BMD, geometry, and bone strength in young girls. Osteoporosis Int;. [Epub ahead of print]; 2010; DOI: 2010.10.1007/s00198-010-1361-8.
26. Aaron DJ, Kriska AM, Dearwater SR, et al. Reproducibility and validity of an epidemiologic questionnaire to assess past year physical activity in adolescents. Am J Epidemiol. 1995; 142: 191-201.
27. Shedd KM, Hanson KB, Alekel DL, et al. Quantifying leisure physical activity and its relation to bone density and strength. Med Sci Sports Exerc. 2007; 39: 2189-2198.
28. Groothausen J, Siemer H, Kemper G, Twisk J, Welten D., Influence of peak strain on lumbar bone mineral density: an analysis of 15-year physical activity in young males and females. Pediatr Exerc Sci. 1997; 9: 159-173.
29. Lohman TG, Roche AF, Martorell R., Anthropometric Standardization Reference Manual. Human Kinetics, Champaign, IL: pp 3-16. 1988.
30. Morris NM, Udry RJ., Validation of a self-administered instrument to assess stage of adolescent development. J Youth Adolesc. 1980; 9: 271-280.
31. Sherar LB, Baxter-Jones AD, Mirwald RL., Limitations to the use of secondary sex characteristics for gender comparisons. Ann Hum Biol. 2004; 31: 586-593.
32. Mirwald RL, Baxter-Jones AD, Bailey DA, Beunen GP., An assessment of maturity from anthropometric measurements. Med Sci Sports Exerc. 2002; 34: 689-694.
33. Bailey DA, McKay HA, Mirwald RL, Crocker PR, Faulkner RA., A six-year longitudinal study of the relationship of physical activity to bone mineral accrual in growing children: The University of Saskatchewan Bone Mineral Accrual Study. J Bone Miner Res. 1999; 14: 1672-1679.
34. Lee DC, Gilsanz V, Wren TA., Limitations of peripheral quantitative computed tomography metaphyseal bone density measurements. J Clin Endocrinol Metab. 2007; 92: 4248-4253.
35. Stratec Medizintchnik 2004 XCT 3000 manual, software version 6.0 Pforzheim, Germany.
36. Bachrach LK., Osteoporosis in children: still a diagnostic challenge. J Clin Endocrinol Metab. 2007; 92: 2030-2032.
37. Gordon CM, Bachrach LK, Carpenter TO, et al. Dual energy X-ray absorptiometry interpretation and reporting in children and adolescents: the 2007 ISCD Pediatric Official Positions. J Clin Densitom. 2008; 11: 43-58.
38. Gluer CC, Blake G, Lu Y, et al. Accurate assessment of precision errors: how to measure the reproducibility of bone densitometry techniques. Osteoporos Int. 1995; 5: 262-270.
39. Going S, Lohman T, Houtkooper L, et al. Effects of exercise on bone mineral density in calcium-replete postmenopausal women with and without hormone replacement therapy. Osteoporos Int. 2003; 14: 637-643.
40. Prentice A, Parsons TJ, Cole TJ., Uncritical use of bone mineral density in absorptiometry may lead to size-related artifacts in the identification of bone mineral determinants. Am J Clin Nutr. 1994; 60: 837-842.
41. Kuczmarski RJ, Ogden CL, Grummer-Strawn LM, et al. CDC growth charts: United States. Adv Data. 2000; 8: 1-27.
42. Kirmani S, Christen D, van Lenthe GH, et al. Bone structure at the distal radius during adolescent growth. J Bone Miner Res. 2009; 24: 1033-1042.
43. Cook SD, Harding AF, Morgan EL, et al. Association of bone mineral density and pediatric fractures. J Pediatr Orthop. 1987; 7: 424-427.
44. Ma DQ, Jones G., Clinical risk factors but not bone density are associated with prevalent fractures in prepubertal children. J Paediatr Child Health. 2002; 38: 497-500.
45. Goulding A, Rockell JE, Black RE, et al. Children who avoid drinking cows milk are at increased risk for prepubertal bone fractures. J Am Diet Assoc. 2004; 104: 250-253.
46. Taes Y, Lapauw B, Griet V, et al. Prevalent fractures are related to cortical bone geometry in young healthy men at age of peak bone mass. J Bone Miner Res. 2010; 25: 1433-1440.
47. Augat P, Gordon CL, Lang TF, Iida H, Genant HK., Accuracy of cortical and trabecular bone measurements with peripheral quantitative computed tomography (pQCT). Phys Med Biol. 1998; 43: 2873-2883.
48. Melton LJ 3rd, Riggs BL, Keaveny TM, et al. Structural determinants of vertebral fracture risk. J Bone Miner Res. 2007; 22: 1885-1892.
49. Sornay-Rendu E, Boutroy S, Munoz F, Delmas PD., Alterations of cortical and trabecular architecture are associated with fractures in postmenopausal women, partially independent of decreased BMD measured by DXA: the OFELY study. J Bone Miner Res. 2007; 22: 425-433.