-
1
-
-
79952370202
-
The cancer stem cell: premises, promises and challenges
-
Clevers H. The cancer stem cell: premises, promises and challenges. Nat Med 2011; 17: 313-9.
-
(2011)
Nat Med
, vol.17
, pp. 313-319
-
-
Clevers, H.1
-
2
-
-
42549099061
-
The cancer stem cell hypothesis: in search of definitions, markers, and relevance
-
Shipitsin M, Polyak K. The cancer stem cell hypothesis: in search of definitions, markers, and relevance. Lab Invest 2008; 88: 459-63.
-
(2008)
Lab Invest
, vol.88
, pp. 459-463
-
-
Shipitsin, M.1
Polyak, K.2
-
3
-
-
69449096005
-
Heterogeneity in cancer: cancer stem cells versus clonal evolution
-
Shackleton M, Quintana E, Fearon ER, Morrison SJ. Heterogeneity in cancer: cancer stem cells versus clonal evolution. Cell 2009; 138: 822-9.
-
(2009)
Cell
, vol.138
, pp. 822-829
-
-
Shackleton, M.1
Quintana, E.2
Fearon, E.R.3
Morrison, S.J.4
-
4
-
-
0037388204
-
Prospective identification of tumorigenic breast cancer cells
-
Al-Hajj M, Wicha MS, Benito-Hernandez A, Morrison SJ, Clarke MF. Prospective identification of tumorigenic breast cancer cells. Proc Natl Acad Sci U S A 2003; 100: 3983-8.
-
(2003)
Proc Natl Acad Sci U S A
, vol.100
, pp. 3983-3988
-
-
Al-Hajj, M.1
Wicha, M.S.2
Benito-Hernandez, A.3
Morrison, S.J.4
Clarke, M.F.5
-
5
-
-
28244472369
-
Prospective identification of tumorigenic prostate cancer stem cells
-
Collins AT, Berry PA, Hyde C, Stower MJ, Maitland NJ. Prospective identification of tumorigenic prostate cancer stem cells. Cancer Res 2005; 65: 10.
-
(2005)
Cancer Res
, vol.65
, pp. 10
-
-
Collins, A.T.1
Berry, P.A.2
Hyde, C.3
Stower, M.J.4
Maitland, N.J.5
-
6
-
-
33847052127
-
Identification of pancreatic cancer stem cells
-
Li C, Heidt DG, Dalerba P et al. Identification of pancreatic cancer stem cells. Cancer Res 2007; 67: 1030-7.
-
(2007)
Cancer Res
, vol.67
, pp. 1030-1037
-
-
Li, C.1
Heidt, D.G.2
Dalerba, P.3
-
7
-
-
0141842674
-
Identification of a cancer stem cell in human brain tumors
-
Singh SK, Clarke ID, Terasaki M et al. Identification of a cancer stem cell in human brain tumors. Cancer Res 2003; 63: 5821-8.
-
(2003)
Cancer Res
, vol.63
, pp. 5821-5828
-
-
Singh, S.K.1
Clarke, I.D.2
Terasaki, M.3
-
8
-
-
38349165576
-
Identification of cells initiating human melanomas
-
Schatton T, Murphy GF, Frank NY et al. Identification of cells initiating human melanomas. Nature 2008; 451: 345-9.
-
(2008)
Nature
, vol.451
, pp. 345-349
-
-
Schatton, T.1
Murphy, G.F.2
Frank, N.Y.3
-
9
-
-
33846512398
-
Identification of a subpopulation of cells with cancer stem cell properties in head and neck squamous cell carcinoma
-
Prince ME, Sivanandan R, Kaczorowski A et al. Identification of a subpopulation of cells with cancer stem cell properties in head and neck squamous cell carcinoma. Proc Natl Acad Sci U S A 2007; 104: 973-8.
-
(2007)
Proc Natl Acad Sci U S A
, vol.104
, pp. 973-978
-
-
Prince, M.E.1
Sivanandan, R.2
Kaczorowski, A.3
-
10
-
-
33947095683
-
CD133, one of the markers of cancer stem cells in Hep-2 cell line
-
Zhou L, Wei X, Cheng L, Tian J, Jiang JJ. CD133, one of the markers of cancer stem cells in Hep-2 cell line. Laryngoscope 2007; 117: 455-60.
-
(2007)
Laryngoscope
, vol.117
, pp. 455-460
-
-
Zhou, L.1
Wei, X.2
Cheng, L.3
Tian, J.4
Jiang, J.J.5
-
11
-
-
67349209852
-
Aldehyde dehydrogenase 1 is a putative marker for cancer stem cells in head and neck squamous cancer
-
Chen YC, Chen YW, Hsu HS et al. Aldehyde dehydrogenase 1 is a putative marker for cancer stem cells in head and neck squamous cancer. Biochem Biophys Res Commun 2009; 385: 307-13.
-
(2009)
Biochem Biophys Res Commun
, vol.385
, pp. 307-313
-
-
Chen, Y.C.1
Chen, Y.W.2
Hsu, H.S.3
-
12
-
-
45549096553
-
Cancer stem cells in head and neck squamous cell cancer
-
Prince MEP, Ailles LE. Cancer stem cells in head and neck squamous cell cancer. J Clin Oncol 2008; 26: 2871-5.
-
(2008)
J Clin Oncol
, vol.26
, pp. 2871-2875
-
-
Prince, M.E.P.1
Ailles, L.E.2
-
13
-
-
36349006961
-
Development and characterization of gemcitabine-resistant pancreatic tumor cells
-
Shah AN, Summy JM, Zhang J, Park SI, Parikh NU, Gallick GE. Development and characterization of gemcitabine-resistant pancreatic tumor cells. Ann Surg Oncol 2007; 14: 3629-37.
-
(2007)
Ann Surg Oncol
, vol.14
, pp. 3629-3637
-
-
Shah, A.N.1
Summy, J.M.2
Zhang, J.3
Park, S.I.4
Parikh, N.U.5
Gallick, G.E.6
-
14
-
-
36248961179
-
Tumorigenesis of chemotherapeutic drug-resistant cancer stem-like cells in brain glioma
-
Kang MK, Kang SK. Tumorigenesis of chemotherapeutic drug-resistant cancer stem-like cells in brain glioma. Stem Cells Dev 2007; 16: 837-47.
-
(2007)
Stem Cells Dev
, vol.16
, pp. 837-847
-
-
Kang, M.K.1
Kang, S.K.2
-
15
-
-
49149107236
-
Colorectal cancer stem cells are enriched in xenogeneic tumors following chemotherapy
-
Dylla SJ, Beviglia L, Park IK et al. Colorectal cancer stem cells are enriched in xenogeneic tumors following chemotherapy. PLoS ONE 2008; 3: e2428.
-
(2008)
PLoS ONE
, vol.3
-
-
Dylla, S.J.1
Beviglia, L.2
Park, I.K.3
-
16
-
-
79952384705
-
Cancer epigenetics reaches mainstream oncology
-
Rodriguez-Paredes M, Esteller M. Cancer epigenetics reaches mainstream oncology. Nat Med 2011; 17: 330-9.
-
(2011)
Nat Med
, vol.17
, pp. 330-339
-
-
Rodriguez-Paredes, M.1
Esteller, M.2
-
18
-
-
73949128107
-
Histone deacetylase inhibitors in cancer therapy
-
Lane AA, Chabner BA. Histone deacetylase inhibitors in cancer therapy. J Clin Oncol 2009; 27: 5459-68.
-
(2009)
J Clin Oncol
, vol.27
, pp. 5459-5468
-
-
Lane, A.A.1
Chabner, B.A.2
-
19
-
-
67650090545
-
Histone deacetylase inhibitors: potential in cancer therapy
-
Marks PA, Xu WS. Histone deacetylase inhibitors: potential in cancer therapy. J Cell Biochem 2009; 107: 600-8.
-
(2009)
J Cell Biochem
, vol.107
, pp. 600-608
-
-
Marks, P.A.1
Xu, W.S.2
-
20
-
-
0030797585
-
Activation of p53 sequence-specific DNA binding by acetylation of the p53 C-terminal domain
-
Gu W, Roeder RG. Activation of p53 sequence-specific DNA binding by acetylation of the p53 C-terminal domain. Cell 1997; 90: 595-606.
-
(1997)
Cell
, vol.90
, pp. 595-606
-
-
Gu, W.1
Roeder, R.G.2
-
21
-
-
0035979737
-
Duration of nuclear NF-kappaB action regulated by reversible acetylation
-
Chen L-F, Fischle W, Verdin E, Greene WC. Duration of nuclear NF-kappaB action regulated by reversible acetylation. Science 2001; 293: 1653-7.
-
(2001)
Science
, vol.293
, pp. 1653-1657
-
-
Chen, L.-F.1
Fischle, W.2
Verdin, E.3
Greene, W.C.4
-
22
-
-
12244251445
-
Stat3 dimerization regulated by reversible acetylation of a single lysine residue
-
Yuan ZL, Guan YJ, Chatterjee D, Chin YE. Stat3 dimerization regulated by reversible acetylation of a single lysine residue. Science 2005; 307: 269-73.
-
(2005)
Science
, vol.307
, pp. 269-273
-
-
Yuan, Z.L.1
Guan, Y.J.2
Chatterjee, D.3
Chin, Y.E.4
-
23
-
-
67449095320
-
Expansion and characterization of cancer stem-like cells in squamous cell carcinoma of the head and neck
-
Okamoto A, Chikamatsu K, Sakakura K, Hatsushika K, Takahashi G, Masuyama K. Expansion and characterization of cancer stem-like cells in squamous cell carcinoma of the head and neck. Oral Oncol 2009; 45: 633-9.
-
(2009)
Oral Oncol
, vol.45
, pp. 633-639
-
-
Okamoto, A.1
Chikamatsu, K.2
Sakakura, K.3
Hatsushika, K.4
Takahashi, G.5
Masuyama, K.6
-
24
-
-
33846095137
-
Identification and expansion of human colon-cancer-initiating cells
-
Ricci-Vitiani L, Lombardi DG, Pilozzi E et al. Identification and expansion of human colon-cancer-initiating cells. Nature 2007; 445: 111-5.
-
(2007)
Nature
, vol.445
, pp. 111-115
-
-
Ricci-Vitiani, L.1
Lombardi, D.G.2
Pilozzi, E.3
-
25
-
-
33646358694
-
Tumor stem cells derived from glioblastomas cultured in bFGF and EGF more closely mirror the phenotype and genotype of primary tumors than do serum-cultured cell lines
-
Lee J, Kotliarova S, Kotliarov Y et al. Tumor stem cells derived from glioblastomas cultured in bFGF and EGF more closely mirror the phenotype and genotype of primary tumors than do serum-cultured cell lines. Cancer Cell 2006; 9: 391-403.
-
(2006)
Cancer Cell
, vol.9
, pp. 391-403
-
-
Lee, J.1
Kotliarova, S.2
Kotliarov, Y.3
-
26
-
-
84856961715
-
Resistance to apoptosis-inducing stimuli in CD44 + head and neck squamous cell carcinoma cells
-
Chikamatsu K, Ishii H, Takahashi G et al. Resistance to apoptosis-inducing stimuli in CD44 + head and neck squamous cell carcinoma cells. Head Neck 2012; 34: 336-43.
-
(2012)
Head Neck
, vol.34
, pp. 336-343
-
-
Chikamatsu, K.1
Ishii, H.2
Takahashi, G.3
-
27
-
-
70349873330
-
CD44-positive cells are responsible for gemcitabine resistance in pancreatic cancer cells
-
Hong SP, Wen J, Bang S, Park S, Song SY. CD44-positive cells are responsible for gemcitabine resistance in pancreatic cancer cells. Int J Cancer 2009; 125: 2323-31.
-
(2009)
Int J Cancer
, vol.125
, pp. 2323-2331
-
-
Hong, S.P.1
Wen, J.2
Bang, S.3
Park, S.4
Song, S.Y.5
-
28
-
-
3342985741
-
Promotion of neurite and filopodium formation by CD47: roles of integrins, Rac, and Cdc42
-
Miyashita M, Ohnishi H, Okazawa H et al. Promotion of neurite and filopodium formation by CD47: roles of integrins, Rac, and Cdc42. Mol Biol Cell 2004; 15: 3950-63.
-
(2004)
Mol Biol Cell
, vol.15
, pp. 3950-3963
-
-
Miyashita, M.1
Ohnishi, H.2
Okazawa, H.3
-
29
-
-
7244240741
-
Modified fixed-ratio isobologram method for studying in vitro interactions between atovaquone and proguanil or dihydroartemisinin against drug-resistant strains of Plasmodium falciparum
-
Fivelman QL, Adagu IS, Warhurst DC. Modified fixed-ratio isobologram method for studying in vitro interactions between atovaquone and proguanil or dihydroartemisinin against drug-resistant strains of Plasmodium falciparum. Antimicrob Agents Chemother 2004; 48: 4097-102.
-
(2004)
Antimicrob Agents Chemother
, vol.48
, pp. 4097-4102
-
-
Fivelman, Q.L.1
Adagu, I.S.2
Warhurst, D.C.3
-
30
-
-
34547864236
-
Histone deacetylase inhibitors: molecular mechanisms of action
-
Xu WS, Parmigiani RB, Marks PA. Histone deacetylase inhibitors: molecular mechanisms of action. Oncogene 2007; 26: 5541-52.
-
(2007)
Oncogene
, vol.26
, pp. 5541-5552
-
-
Xu, W.S.1
Parmigiani, R.B.2
Marks, P.A.3
-
31
-
-
0042905956
-
Gene expression profiling of multiple histone deacetylase (HDAC) inhibitors: defining a common gene set produced by HDAC inhibition in T24 and MDA carcinoma cell lines
-
Glaser KB, Staver MJ, Waring JF, Stender J, Ulrich RG, Davidsen SK. Gene expression profiling of multiple histone deacetylase (HDAC) inhibitors: defining a common gene set produced by HDAC inhibition in T24 and MDA carcinoma cell lines. Mol Cancer Ther 2003; 2: 151-63.
-
(2003)
Mol Cancer Ther
, vol.2
, pp. 151-163
-
-
Glaser, K.B.1
Staver, M.J.2
Waring, J.F.3
Stender, J.4
Ulrich, R.G.5
Davidsen, S.K.6
-
32
-
-
14844353574
-
Identification and functional significance of genes regulated by structurally different histone deacetylase inhibitors
-
Peart MJ, Smyth GK, van Laar RK et al. Identification and functional significance of genes regulated by structurally different histone deacetylase inhibitors. Proc Natl Acad Sci U S A 2005; 102: 3697-702.
-
(2005)
Proc Natl Acad Sci U S A
, vol.102
, pp. 3697-3702
-
-
Peart, M.J.1
Smyth, G.K.2
van Laar, R.K.3
-
33
-
-
0037589018
-
Molecular sequelae of histone deacetylase inhibition in human malignant B cells
-
Mitsiades N, Mitsiades CS, Richardson PG et al. Molecular sequelae of histone deacetylase inhibition in human malignant B cells. Blood 2003; 101: 4055-62.
-
(2003)
Blood
, vol.101
, pp. 4055-4062
-
-
Mitsiades, N.1
Mitsiades, C.S.2
Richardson, P.G.3
-
34
-
-
0034730127
-
Histone deacetylase inhibitor selectively induces p21WAF1 expression and gene-associated histone acetylation
-
Richon VM, Sandhoff TW, Rifkind RA, Marks PA. Histone deacetylase inhibitor selectively induces p21WAF1 expression and gene-associated histone acetylation. Proc Natl Acad Sci U S A 2000; 97: 10014-9.
-
(2000)
Proc Natl Acad Sci U S A
, vol.97
, pp. 10014-10019
-
-
Richon, V.M.1
Sandhoff, T.W.2
Rifkind, R.A.3
Marks, P.A.4
-
35
-
-
16544366235
-
CD44 in cancer progression: adhesion, migration and growth regulation
-
Marhaba R, Zoller M. CD44 in cancer progression: adhesion, migration and growth regulation. J Mol Histol 2004; 35: 211-31.
-
(2004)
J Mol Histol
, vol.35
, pp. 211-231
-
-
Marhaba, R.1
Zoller, M.2
-
36
-
-
0037277035
-
CD44 and its partners in metastasis
-
Jothy S. CD44 and its partners in metastasis. Clin Exp Metastasis 2003; 20: 195-201.
-
(2003)
Clin Exp Metastasis
, vol.20
, pp. 195-201
-
-
Jothy, S.1
-
37
-
-
47749116454
-
Hyaluronan-CD44 interaction activates stem cell marker Nanog, Stat-3-mediated MDR1 gene expression, and ankyrin-regulated multidrug efflux in breast and ovarian tumor cells
-
Bourguignon LYW, Peyrollier K, Xia W, Gilad E. Hyaluronan-CD44 interaction activates stem cell marker Nanog, Stat-3-mediated MDR1 gene expression, and ankyrin-regulated multidrug efflux in breast and ovarian tumor cells. J Biol Chem 2008; 283: 17.
-
(2008)
J Biol Chem
, vol.283
, pp. 17
-
-
Bourguignon, L.Y.W.1
Peyrollier, K.2
Xia, W.3
Gilad, E.4
-
38
-
-
33750302541
-
SP analysis may be used to identify cancer stem cell populations
-
Hadnagy A, Gaboury L, Beaulieu R, Balicki D. SP analysis may be used to identify cancer stem cell populations. Exp Cell Res 2006; 312: 3701-10.
-
(2006)
Exp Cell Res
, vol.312
, pp. 3701-3710
-
-
Hadnagy, A.1
Gaboury, L.2
Beaulieu, R.3
Balicki, D.4
-
39
-
-
48349133869
-
Side population cells in human cancers
-
Wu C, Alman BA. Side population cells in human cancers. Cancer Lett 2008; 268: 1-9.
-
(2008)
Cancer Lett
, vol.268
, pp. 1-9
-
-
Wu, C.1
Alman, B.A.2
-
40
-
-
40749118502
-
Histone modifications at the ABCG2 promoter following treatment with histone deacetylase inhibitor mirror those in multidrug-resistant cells
-
To KKW, Polgar O, Huff LM, Morisaki K, Bates SE. Histone modifications at the ABCG2 promoter following treatment with histone deacetylase inhibitor mirror those in multidrug-resistant cells. Mol Cancer Res 2008; 6: 151-64.
-
(2008)
Mol Cancer Res
, vol.6
, pp. 151-164
-
-
To, K.K.W.1
Polgar, O.2
Huff, L.M.3
Morisaki, K.4
Bates, S.E.5
-
41
-
-
43049165453
-
The epithelial-mesenchymal transition generates cells with properties of stem cells
-
Mani SA, Guo W, Liao M-J et al. The epithelial-mesenchymal transition generates cells with properties of stem cells. Cell 2008; 133: 704-15.
-
(2008)
Cell
, vol.133
, pp. 704-715
-
-
Mani, S.A.1
Guo, W.2
Liao, M.-J.3
-
42
-
-
51449085561
-
Generation of breast cancer stem cells through epithelial-mesenchymal transition
-
Morel AP, Lievre M, Thomas C, Hinkal G, Ansieau S, Puisieux A. Generation of breast cancer stem cells through epithelial-mesenchymal transition. PLoS ONE 2008; 3: e2888.
-
(2008)
PLoS ONE
, vol.3
-
-
Morel, A.P.1
Lievre, M.2
Thomas, C.3
Hinkal, G.4
Ansieau, S.5
Puisieux, A.6
-
43
-
-
66149131111
-
Immune-induced epithelial to mesenchymal transition in vivo generates breast cancer stem cells
-
Santisteban M, Reiman JM, Asiedu MK et al. Immune-induced epithelial to mesenchymal transition in vivo generates breast cancer stem cells. Cancer Res 2009; 69: 2887-95.
-
(2009)
Cancer Res
, vol.69
, pp. 2887-2895
-
-
Santisteban, M.1
Reiman, J.M.2
Asiedu, M.K.3
-
44
-
-
65649095142
-
Side population of pancreatic cancer cells predominates in TGF-beta-mediated epithelial to mesenchymal transition and invasion
-
Kabashima A, Higuchi H, Takaishi H et al. Side population of pancreatic cancer cells predominates in TGF-beta-mediated epithelial to mesenchymal transition and invasion. Int J Cancer 2009; 124: 2771-9.
-
(2009)
Int J Cancer
, vol.124
, pp. 2771-2779
-
-
Kabashima, A.1
Higuchi, H.2
Takaishi, H.3
-
45
-
-
79551522569
-
Evidence for epithelial-mesenchymal transition in cancer stem cells of head and neck squamous cell carcinoma
-
Chen CC, Wei Y, Hummel M et al. Evidence for epithelial-mesenchymal transition in cancer stem cells of head and neck squamous cell carcinoma. PLoS ONE 2011; 6: e16466.
-
(2011)
PLoS ONE
, vol.6
-
-
Chen, C.C.1
Wei, Y.2
Hummel, M.3
-
46
-
-
79958719758
-
HDAC inhibitor vorinostat enhances the antitumor effect of gefitinib in squamous cell carcinoma of head and neck by modulating ErbB receptor expression and reverting EMT
-
Bruzzese F, Leone A, Rocco M et al. HDAC inhibitor vorinostat enhances the antitumor effect of gefitinib in squamous cell carcinoma of head and neck by modulating ErbB receptor expression and reverting EMT. J Cell Physiol 2011; 226: 2378-90.
-
(2011)
J Cell Physiol
, vol.226
, pp. 2378-2390
-
-
Bruzzese, F.1
Leone, A.2
Rocco, M.3
-
47
-
-
33845976704
-
Inhibition of histone deacetylase activity suppresses epithelial-to-mesenchymal transition induced by TGF-β1 in human renal epithelial cells
-
Yoshikawa M, Hishikawa K, Marumo T, Fujita T. Inhibition of histone deacetylase activity suppresses epithelial-to-mesenchymal transition induced by TGF-β1 in human renal epithelial cells. J Am Soc Nephrol 2007; 18: 58-65.
-
(2007)
J Am Soc Nephrol
, vol.18
, pp. 58-65
-
-
Yoshikawa, M.1
Hishikawa, K.2
Marumo, T.3
Fujita, T.4
-
48
-
-
84866419172
-
Histone deacetylase inhibitors induce epithelial-to-mesenchymal transition in prostate cancer cells
-
Kong D, Ahmad A, Bao B, Li Y, Banerjee S, Sarkar FH. Histone deacetylase inhibitors induce epithelial-to-mesenchymal transition in prostate cancer cells. PLoS ONE 2012; 7: e45045.
-
(2012)
PLoS ONE
, vol.7
-
-
Kong, D.1
Ahmad, A.2
Bao, B.3
Li, Y.4
Banerjee, S.5
Sarkar, F.H.6
-
49
-
-
84856911804
-
Studies using an in vitro model show evidence of involvement of epithelial-mesenchymal transition of human endometrial epithelial cells in human embryo implantation
-
Uchida H, Maruyama T, Nishikawa-Uchida S et al. Studies using an in vitro model show evidence of involvement of epithelial-mesenchymal transition of human endometrial epithelial cells in human embryo implantation. J Biol Chem 2012; 287: 4441-50.
-
(2012)
J Biol Chem
, vol.287
, pp. 4441-4450
-
-
Uchida, H.1
Maruyama, T.2
Nishikawa-Uchida, S.3
-
50
-
-
21244464349
-
Phase I study of an oral histone deacetylase inhibitor, suberoylanilide hydroxamic acid, in patients with advanced cancer
-
Kelly WK, O'Connor OA, Krug ML et al. Phase I study of an oral histone deacetylase inhibitor, suberoylanilide hydroxamic acid, in patients with advanced cancer. J Clin Oncol 2005; 23: 3923-31.
-
(2005)
J Clin Oncol
, vol.23
, pp. 3923-3931
-
-
Kelly, W.K.1
O'Connor, O.A.2
Krug, M.L.3
-
51
-
-
38149140216
-
Phase II trial of the histone deacetylase inhibitor vorinostat (Zolionza™, suberoylanilide hydroxamic acid, SAHA) in patients with recurrent and/or metastatic head and neck cancer
-
Blumenschein GR Jr, Kies MS, Papadimitrakopoulou VA et al. Phase II trial of the histone deacetylase inhibitor vorinostat (Zolionza™, suberoylanilide hydroxamic acid, SAHA) in patients with recurrent and/or metastatic head and neck cancer. Invest New Drugs 2008; 26: 81-7.
-
(2008)
Invest New Drugs
, vol.26
, pp. 81-87
-
-
Blumenschein Jr, G.R.1
Kies, M.S.2
Papadimitrakopoulou, V.A.3
|