Sequencing of modern Lepus VDJ genes shows that the usage of VHn genes has been retained in both Oryctolagus and Lepus that diverged 12 million years ago

Immunogenetics

Volumn 65, Issue 11, 2013, Pages 777-784

  Pinheiro, Ana ^a,b,c   De Mera, Isabel G Fernández ^c,d   Alves, Paulo C ^a,b,e   Gortázar, Christian ^c   De La Fuente, José ^c,f   Esteves, Pedro J ^a,g  

^a CENTRO DE INVESTIGAÇÃO EM BIODIVERSIDADE E RECURSOS GENÉTICOS   (Portugal)

^b UNIVERSITY OF PORTO   (Portugal)

^c INSTITUTO DE INVESTIGACIÓN EN RECURSOS CINEGÉTICOS IREC CSIC UCLM JCCM   (Spain)

^d UNIVERSIDAD COMPLUTENSE DE MADRID   (Spain)

^e UNIVERSITY OF MONTANA   (United States)

^f OKLAHOMA STATE UNIVERSITY   (United States)

^g INSTITUTO DE INVESTIGAÇÃO E FORMAÇÃO AVANÇADA EM CIÊNCIAS E TECNOLOGIAS DA SAÚDE   (Portugal)

Author keywords

Antibody diversification; Evolution; IGHV; Leporids; Vh allotypes

Indexed keywords

ARTICLE; GENE; GENE REARRANGEMENT; GENE SEQUENCE; GENETIC POLYMORPHISM; GENETIC VARIABILITY; HARE; IMMUNE RESPONSE; NONHUMAN; NUCLEOTIDE SEQUENCE; ORYCTOLAGUS; PRIORITY JOURNAL; VDJ EXON; VH GENE;

AMINO ACID SEQUENCE; ANIMALS; EVOLUTION, MOLECULAR; GENES, IMMUNOGLOBULIN; HARES; IMMUNOGLOBULIN HEAVY CHAINS; IMMUNOGLOBULIN VARIABLE REGION; MOLECULAR SEQUENCE DATA; PHYLOGENY; RABBITS; SEQUENCE HOMOLOGY, AMINO ACID; V(D)J RECOMBINATION;

LEPORIDAE; LEPUS; LEPUS EUROPAEUS; MAMMALIA; ORYCTOLAGUS; ORYCTOLAGUS CUNICULUS;

EID: 84886789456     PISSN: 00937711     EISSN: 14321211     Source Type: Journal    
DOI: 10.1007/s00251-013-0728-3     Document Type: Article

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