Allelic Variation at the VHa Locus in Natural Populations of Rabbit (Oryctolagus cuniculus, L.)

Journal of Immunology

Volumn 172, Issue 2, 2004, Pages 1044-1053

  Esteves, Pedro J ^a,b,c   Lanning, Dennis ^d   Ferrand, Nuno ^a,b   Knight, Katherine L ^d   Zhai, Shi Kang ^d   Van Der Loo, Wessel ^a,b,c  

^a CENTRO DE INVESTIGAÇÃO EM BIODIVERSIDADE E RECURSOS GENÉTICOS   (Portugal)

^b UNIVERSITY OF PORTO   (Portugal)

^c VRIJE UNIVERSITEIT BRUSSEL   (Belgium)

^d LOYOLA UNIVERSITY CHICAGO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALLELE; ANIMAL CELL; ARTICLE; CELL POPULATION; CROSS REACTION; GENE CONVERSION; GENE EXPRESSION REGULATION; GENE LOCUS; GENE REARRANGEMENT; GENETIC POLYMORPHISM; IMMUNOGLOBULIN GENE; IMMUNOGLOBULIN VARIABLE REGION; IMMUNOGLOBULIN VH GENE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; RABBIT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; UNINDEXED SEQUENCE; ALLELIC IMBALANCE; AMINO ACID SEQUENCE; ANIMAL; ANTIBODY SPECIFICITY; BIOSYNTHESIS; BLOOD; DNA SEQUENCE; GENETIC MARKER; GENETIC VARIABILITY; GENETICS; IMMUNOLOGY; MOLECULAR GENETICS; MULTIGENE FAMILY; SPECIES DIFFERENCE; WILD ANIMAL;

ORYCTOLAGUS CUNICULUS;

IMMUNOGLOBULIN ALLOTYPE; IMMUNOGLOBULIN HEAVY CHAIN; MITOCHONDRIAL DNA;

ALLELES; ALLELIC IMBALANCE; AMINO ACID SEQUENCE; ANIMALS; ANIMALS, WILD; ANTIBODY DIVERSITY; DNA, MITOCHONDRIAL; GENE CONVERSION; GENE EXPRESSION REGULATION; GENE REARRANGEMENT, B-LYMPHOCYTE, HEAVY CHAIN; GENETIC MARKERS; IMMUNOGLOBULIN ALLOTYPES; IMMUNOGLOBULIN HEAVY CHAINS; IMMUNOGLOBULIN VARIABLE REGION; MOLECULAR SEQUENCE DATA; MULTIGENE FAMILY; RABBITS; SEQUENCE ANALYSIS, DNA; SPECIES SPECIFICITY; VARIATION (GENETICS);

EID: 1642577087     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.172.2.1044     Document Type: Article

References (52)

1. Kim, B. S., and S. Dray. 1972. Identification and genetic control of allotypic specificities on two variable region subgroups of rabbit immunoglobulin heavy chains. Eur. J. Immunol. 2:509.
2. Kim, B. S., and S. Dray. 1973. Expression of the a, x, and y variable region genes of heavy chains among IgG, IgM, and IgA molecules of normal and a locus allotype-suppressed rabbits. J. Immunol. 111:750.
3. Roux, K. H. 1981. A fourth heavy chain variable region subgroup, w, with 2 variants defined by an induced auto-antiserum in the rabbit. J. Immunol. 127:626.
4. Oudin, J. 1960. L'allotypie de certains antigènes proteidiques du sérum. Relation immunochimiques et génétiques entre six des principaux allotypes observés dans le sérum de lapin. CR Acad. Sci. Paris 242:2489.
5. Dray, S. G., O. Young, and A. Nisonoff. 1963. Distribution of allotypic specificities among rabbit immunoglobulin γ-globulin molecules genetically defined at two loci. Nature 199:52.
6. Ha allotypes of the rabbit. Mol. Immunol. 21:1067.
7. Knight, K. L., and R. S. Becker. 1990. Molecular basis of the allelic inheritance of rabbit immunoglobulin VH allotypes: Implications for the generation of antibody diversity. Cell 60:963.
8. Gallarda, J. L., K. S. Gleason, and K. L. Knight. 1985. Organization of rabbit immunoglobulin genes. I. Structure and multiplicity of germ-line VH genes. J. Immunol. 135:4222.
9. Becker, R. S., and K. L. Knight. 1990. Somatic diversification of immunoglobulin heavy chain VDJ genes: Evidence for somatic gene conversion in rabbits. Cell 63:987.
10. Kelus, A. S., and S. Weiss. 1986. Mutation affecting the expression of immunoglobulin variable regions in the rabbit. Proc. Natl. Acad. Sci. USA 83:4883.
11. Di Pietro, L. A., J. A. Short, S. K. Zhai, A. S. Kelus, D. Meier, and K. L. Knight. 1990. Limited number of immunoglobulin VH regions expressed in the mutant rabbit "Alicia". Eur. J. Immunol. 20:1401.
12. Short, J. A., P. Sethupathi, S. K. Zhai, and K. L. Knight. 1991. VDJ genes in VHa2 allotype-suppressed rabbits. Limited germline VH gene usage and accumulation of somatic mutations in D regions. J. Immunol. 147:4014.
13. Kelus, A. S., and P. G. Gell. 1967. Immunoglobulin allotypes of experimental animals. Prog. Allergy 11:141.
14. Smith, G. P. 1976. Evolution of repeated DNA sequences by unequal crossover. Science 191:528.
15. Su, C., and M. Nei. 1999. Fifty-million-year-old polymorphism at an immunoglobulin variable region gene locus in the rabbit evolutionary lineage. Proc. Natl. Acad. Sci. USA 96:9710.
16. + B cells predominate in peripheral tissues of rabbit. J. Immunol. 149:3858.
17. Pospisil, R., and R. G. Mage. 1998. CD5 and other superantigens as 'ticklers' of the B-cell receptor. Immunol. Today 19:106.
18. Mage, R. G., and Pospisil, R. 2000. CD5 and other superantigens may select and maintain rabbit self-renewing B-lymphocytes and human B-CLL cells. Curr. Top. Microbiol. Immunol. 252:87.
19. Lopez-Martinez, N. 1989. Revision sistematica y biostratigrafica de los lagomorphos (Mammalia) del Terciario y Cuaternario de España. Memorias del Museo Paleontologico de la Universidad de Zaragoza, no3. Diputacion General de Aragon.
20. Callou, C. 1995. Modifications de l'aire de répartition du Lapin (Oryctolagus cuniculus) en France et en Espagne, du Pléistocène à l'époque actuelle. État de la question. Anthropozoologica 21:95.
21. Branco, M., N. Ferrand, and M. Monnerot. 2000. Phylogeography of the European rabbit (Oryctolagus cuniculus) in the Iberian Peninsula inferred from RFLP analysis of the cytochrome b gene. Heredity 85:307.
22. Branco, M., M. Monnerot, N. Ferrand, and A. R. Templeton. 2002. Postglacial dispersal of the European rabbit (Oryctolagus cuniculus) on the Iberian Peninsula reconstructed from nested clade and mismatch analyses of mitochondrial DNA genetic variation. Evolution 56:792.
23. Cazenave, P. A., A. Bennamar, J. A. Sogn, and T. J. Kindt. 1987. Immunoglobulin genes in fetal populations. In The Rabbit in Contemporary Immunological Research. S. Dubiski, ed. Longman Scientific & Technical. New York, p. 148.
24. Tonnelle, C., P. A. Cazenave, C. Brezin, D. Moinier, and M. Fougereau. 1983. Structural correlates to the rabbit immunoglobulin heavy chain a100 allotype. Mol. Immunol. 20:753.
25. Hardy C, J. D. Vigne, D. Casane, N. Dennebouy, J. C. Mounoulou, and M. Monnerot. 1994. Origin of European rabbit (Oryctolagus cuniculus) in a Mediterranean island: Zooarchaeology and ancient DNA examination. J. Evol. Biol. 7:217.
26. Monnerot, M., J. D. Vigne, C. Biju-Duval, D. Casane, C. Callou, C. Hardy, F. Mougel, R. Soriguer, N. Dennebouy, and J. C. Mounolou. 1994. Rabbit and man: Genetic and historic approach. Genet. Sel. Evol. 26:167.
27. Asmussen, M. A., and J. Arnold. 1991. The effects of admixture and population subdivision on cytonuclear disequilibria. Theor. Popul. Biol. 39:273.
28. Krug, M. S., and S. L. Berger. 1987. First-strand cDNA synthesis primed with oligo(dT). Methods Enzymol. 152:316.
29. H gene usage in mutant Alicia rabbits. J. Immunol. 163:3313.
30. Thompson, J. D., D. G. Higgins, and T. J. Gibson. 1994. CLUSTAL W: Improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice. Nucleic Acids Res. 22:4673.
31. Xia, X., and Z. Xie. 2001. DAMBE: Software package for data analysis in molecular biology and evolution. J. Hered. 92:371.
32. Nicholas, K. B., H. B. Nicholas, Jr., and D. W. Deerfield, II. 1997. GeneDoc: Analysis and visualization of genetic variation. EMBNEW News 4:14.
33. Kumar, S., K. Tamura, I. B. Jakobsen, and M. Nei. 2001. MEGA2: Molecular evolutionary genetics analysis software. Bioinformatics 17:1244.
34. Nei, M., and S. Kumar. 2000. Molecular Evolution and Phylogenetics. Oxford University Press, Oxford.
35. Saitou, N., and M. Nei. 1987. The neighbor-joining method: A new method for reconstructing phylogenetic trees. Mol. Biol. Evol. 4:406.
36. Felsenstein, J. 1985. Confidence limits on phylogenies: An approach using the bootstrap. Evolution 39:783.
37. Rzhetsky, A., and M. Nei. 1992. Statistical properties of the ordinary least-squares, generalized least-squares, and minimum-evolution methods of phylogenetic inference. J. Mol. Evol. 35:367.
38. Sitnikova, T. 1996. Bootstrap method of interior-branch test for phylogenetic trees. Mol. Biol. Evol. 13:605.
39. Tajima, F. 1993. Simple methods for testing the molecular evolutionary clock hypothesis. Genetics. 135:599.
40. Tutter, A., and R. Riblet. 1989. Evolution of the immunoglobulin heavy chain variable region (Igh-V) locus in the genus Mus. Immunogenetics 30:315.
41. Ota, T., and M. Nei. 1994. Divergent evolution and evolution by the birth-and-death process in the immunoglobulin VH gene family. Mol. Biol. Evol. 11:469.
42. Lefranc, M.-P. 2001. IMGT, the international ImmunoGeneTics database. Nucleic Acids Res. 29:207.
43. Kabat, E. A., T. T. Wu, H. M. Perry, K. S. Gottesman, and C. Foeller. 1991. Sequences of Proteins of Immunologic Interest. U.S. Department of Health and Human Services, Public Health service, National Institutes of Health, Bethesda, MD.
44. Sehgal, D., R. G. Mage, and E. Schiaffella. 1998. VH mutant rabbits lacking the VH1a2 gene develop a2+ B cells in the appendix by gene conversion-like alteration of a rearranged VH4 gene. J. Immunol. 160:1246.
45. Akimenko, M. A., B. Mariame, and F. Rougeon. 1986. Evolution of the immunoglobulin κ light chain locus in the rabbit: Evidence for differential gene conversion events. Proc. Natl. Acad. Sci. USA 83:5180.
46. Lummus, Z., Cebra, J. J., and Mage, R. G. 1967. Correspondence of the relative cellular distribution and serum concentration of allelic allotypic markers in normal and allotype suppressed heterozygous rabbits. J. Immunol. 99:737.
47. Mage, R. G. 1967. Quantitative studies on the regulation of expression of genes for immunoglobulin allotypes in heterozygote rabbits. Cold Spring Harbor Symp. Quant. Biol. 32:203.
48. van der Loo, W., F. Mougel, M. S. Sanchez, C. Bouton, E. Castien, A. Fonseca, N. Ferrand, R. Soriguer, and M. Monnerot. 1999. Cytonuclear disequilibria in wild populations of rabbit (Oryctolagus cuniculus L.) suggest unequal allele turnover rates at the b locus (IGKC1). Immunogenetics 49:629.
49. Cooper, M. D., D. Y. Perey, A. E. Gabrielsen, D. E. Sutherland, M. F. McKneally, and R. A. Good. 1968. Production of an antibody deficiency syndrome in rabbits by neonatal removal of organized intestinal lymphoid tissues. Int. Arch. Allergy Appl. Immunol. 33:65.
50. Lanning, D., X. Zhu, S. K. Zhai, and K. L. Knight. 2000. Development of the antibody repertoire in rabbit: Gut-associated lymphoid tissue, microbes, and selection. Immunol. Rev. 175:214.
51. Graille, M., E. A. Stura, A. L. Corper, B. J. Sutton, M. J. Taussig, J. B. Charbonnier, and G. J. Silverman. 2000. Crystal structure of a Staphylococcus aureus protein A domain complexed with the Fab fragment of a human IgM antibody: Structural basis for recognition of B-cell receptors and superantigen activity. Proc. Natl. Acad. Sci. USA 97:5399.
52. Nguyen, V. K., C. Su, S. Muyldermans, and W. van der Loo. 2002. Heavy-chain antibodies in Camelidae: A case of evolutionary innovation. Immunogenetics 54:39.