Evaluation of the recombinant protein TpF1 of Treponema pallidum for serodiagnosis of syphilis

Clinical and Vaccine Immunology

Volumn 20, Issue 10, 2013, Pages 1563-1568

  Jiang, Chuanhao ^a   Zhao, Feijun ^a   Xiao, Jinhong ^b   Zeng, Tiebing ^a   Yu, Jian ^a   Ma, Xiaohua ^a   Wu, Haiying ^a   Wu, Yimou ^a  

^a UNIVERSITY OF SOUTH CHINA   (China)

^b Hunan Provincial People's Hospital   (China)

Author keywords

[No Author keywords available]

Indexed keywords

IMMUNOGLOBULIN G; RECOMBINANT F1 PROTEIN; RECOMBINANT PROTEIN; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DIAGNOSTIC TEST ACCURACY STUDY; DISEASE ASSOCIATION; ENZYME LINKED IMMUNOSORBENT ASSAY; IMMUNOGENICITY; LEPTOSPIROSIS; LYME DISEASE; MALE; NONHUMAN; OUTCOME ASSESSMENT; PRIORITY JOURNAL; PROTEIN DETERMINATION; PROTEIN SYNTHESIS; RABBIT; SCREENING TEST; SENSITIVITY ANALYSIS; SENSITIVITY AND SPECIFICITY; SYPHILIS; SYPHILIS SEROLOGY; TREPONEMA PALLIDUM; WESTERN BLOTTING;

ANIMALS; ANTIBODIES, BACTERIAL; ANTIGENS, HELMINTH; BLOTTING, WESTERN; ENZYME-LINKED IMMUNOSORBENT ASSAY; HUMANS; IMMUNOGLOBULIN G; MALE; RABBITS; RECOMBINANT PROTEINS; SENSITIVITY AND SPECIFICITY; SEROLOGIC TESTS; SYPHILIS; TREPONEMA PALLIDUM;

EID: 84886731714     PISSN: 15566811     EISSN: 1556679X     Source Type: Journal    
DOI: 10.1128/CVI.00122-13     Document Type: Article

References (33)

1. Lafond RE, Lukehart SA. 2006. Biological basis for syphilis. Clin. Microbiol. Rev. 19:29-49.
2. Daskalakis D. 2008. Syphilis: continuing public health and diagnostic challenges. Curr. HIV/AIDS Rep. 5:72-77.
3. Schmid GP, Stoner BP, Hawkes S, Broutet N. 2007. The need and plan for global elimination of congenital syphilis. Sex. Transm. Dis. 34:S5-10.
4. Yin F, Feng Z, Li X. 2012. Spatial analysis of primary and secondary syphilis incidence in China, 2004-2010. Int. J. STD AIDS 23:870-875.
5. Chow EP, Wilson DP, Zhang L. 2011. HIV and syphilis co-infection increasing among men who have sex with men in China: a systematic review and meta-analysis. PLoS One 6:e22768. doi:10.1371/journal.pone.0022768.
6. Wheeler HL, Agarwal S, Goh BT. 2004. Dark ground microscopy and treponemal serological tests in the diagnosis of early syphilis. Sex. Transm. Infect. 80:411-414.
7. Hoover KW, Radolf JD. 2011. Serodiagnosis of syphilis in the recombinant era: reversal of fortune. J. Infect. Dis. 204:1295-1296.
8. Binnicker MJ, Jespersen DJ, Rollins LO. 2011. Treponema-specific tests for serodiagnosis of syphilis: comparative evaluation of seven assays. J. Clin. Microbiol. 49:1313-1317.
9. Sena AC, White BL, Sparling PF. 2010. Novel Treponema pallidum serologic tests: a paradigm shift in syphilis screening for the 21st century. Clin. Infect. Dis. 51:700-708.
10. Larsen SA, Steiner BM, Rudolph AH. 1995. Laboratory diagnosis and interpretation of tests for syphilis. Clin. Microbiol. Rev. 8:1-21.
11. Welch RJ, Litwin CM. 2010. Evaluation of two immunoblot assays and a Western blot assay for the detection of antisyphilis immunoglobulin g antibodies. Clin. Vaccine Immunol. 17:183-184.
12. Tsang RS, Martin IE, Lau A, Sawatzky P. 2007. Serological diagnosis of syphilis: comparison of the Trep-Chek IgG enzyme immunoassay with other screening and confirmatory tests. FEMS Immunol. Med. Microbiol. 51:118-124.
13. Sun AH, Mao YF, Hu Y, Sun Q, Yan J. 2009. Sensitive and specific ELISA coated by TpN15-TpN17-TpN47 fusion protein for detection of antibodies to Treponema pallidum. Clin. Chem. Lab. Med. 47:321-326.
14. Lin LR, Fu ZG, Dan B, Jing GJ, Tong ML, Chen DT, Yu Y, Zhang CG, Yang TC, Zhang ZY. 2010. Development of a colloidal gold-immunochromatography assay to detect immunoglobulin G antibodies to Treponema pallidum with TPN17 and TPN47. Diagn. Microbiol. Infect. Dis. 68:193-200.
15. Van Voorhis WC, Barrett LK, Lukehart SA, Schmidt B, Schriefer M, Cameron CE. 2003. Serodiagnosis of syphilis: antibodies to recombinant Tp0453, Tp92, and Gpd proteins are sensitive and specific indicators of infection by Treponema pallidum. J. Clin. Microbiol. 41:3668-3674.
16. Smith BC, Simpson Y, Morshed MG, Cowen LL, Hof R, Wetherell C, Cameron CE. 2013. New proteins for a new perspective on syphilis diagnosis. J. Clin. Microbiol. 51:105-111.
17. Brito Moreno AI, Acosta Bas C, Rodriguez M, Baluja Conde IB, Feal Carballo S, Martinez L. 2003. Monoclonal antibodies to the recombinant protein TmpA of the Treponema pallidum. Hybrid. Hybridomics 22:393-396.
18. McGill MA, Edmondson DG, Carroll JA, Cook RG, Orkiszewski RS, Norris SJ. 2010. Characterization and serologic analysis of the Treponema pallidum proteome. Infect. Immun. 78:2631-2643.
19. Lukehart SA, Baker-Zander SA, Sell S. 1980. Characterization of lymphocyte responsiveness in early experimental syphilis. I. In vitro response to mitogens and Treponema pallidum antigens. J. Immunol. 124:454-460.
20. Fraser CM, Norris SJ, Weinstock GM, White O, Sutton GG, Dodson R, Gwinn M, Hickey EK, Clayton R, Ketchum KA, Sodergren E, Hardham JM, McLeod MP, Salzberg S, Peterson J, Khalak H, Richardson D, Howell JK, Chidambaram M, Utterback T, McDonald L, Artiach P, Bowman C, Cotton MD, Fujii C, Garland S, Hatch B, Horst K, Roberts K, Sandusky M, Weidman J, Smith HO, Venter JC. 1998. Complete genome sequence of Treponema pallidum, the syphilis spirochete. Science 281:375-388.
21. Thumiger A, Polenghi A, Papinutto E, Battistutta R, Montecucco C, Zanotti G. 2006. Crystal structure of antigen TpF1 from Treponema pallidum. Proteins 62:827-830.
22. Radolf JD, Borenstein LA, Kim JY, Fehniger TE, Lovett MA. 1987. Role of disulfide bonds in the oligomeric structure and protease resistance of recombinant and native Treponema pallidum surface antigen 4D. J. Bacteriol. 169:1365-1371.
23. Fehniger TE, Radolf JD, Lovett MA. 1986. Properties of an ordered ring structure formed by recombinant Treponema pallidum surface antigen 4D. J. Bacteriol. 165:732-739.
24. Young H. 1998. Syphilis serology. Dermatol. Clin. 16:691-698.
25. Wong EH, Klausner JD, Caguin-Grygiel G, Madayag C, Barber KO, Qiu JS, Liska S, Pandori MW. 2011. Evaluation of an IgM/IgG sensitive enzyme immunoassay and the utility of index values for the screening of syphilis infection in a high-risk population. Sex. Transm. Dis. 38:528-532.
26. Sambri V, Marangoni A, Simone MA, D'Antuono A, Negosanti M, Cevenini R. 2001. Evaluation of recomWell Treponema, a novel recombinant antigen-based enzyme-linked immunosorbent assay for the diagnosis of syphilis. Clin. Microbiol. Infect. 7:200-205.
27. Hunter MG, Robertson PW, Post JJ. 2012. Significance of isolated reactive treponemal chemiluminescence immunoassay results. J. Infect. Dis. 209:1416-1423.
28. Aktas G, Young H, Moyes A, Badur S. 2005. Evaluation of the serodia Treponema pallidum particle agglutination, the Murex Syphilis ICE and the Enzywell TP tests for serodiagnosis of syphilis. Int. J. STD AIDS 16:294-298.
29. Sambri V, Marangoni A, Eyer C, Reichhuber C, Soutschek E, Negosanti M, D'Antuono A, Cevenini R. 2001. Western immunoblotting with five Treponema pallidum recombinant antigens for serologic diagnosis of syphilis. Clin. Diagn. Lab. Immunol. 8:534-539.
30. Rawstron SA, Mehta S, Bromberg K. 2004. Evaluation of a Treponema pallidum-specific IgM enzyme immunoassay and Treponema pallidum Western blot antibody detection in the diagnosis of maternal and congenital syphilis. Sex. Transm. Dis. 31:123-126.
31. Marangoni A, Moroni A, Accardo S, Cevenini R. 2009. Laboratory diagnosis of syphilis with automated immunoassays. J. Clin. Lab. Anal. 23:1-6.
32. Wellinghausen N, Dietenberger H. 2011. Evaluation of two automated chemiluminescence immunoassays, the LIAISON Treponema Screen and the ARCHITECT Syphilis TP, and the Treponema pallidum particle agglutination test for laboratory diagnosis of syphilis. Clin. Chem. Lab. Med. 49:1375-1377.
33. Novikov AI, Dolgikh TI, Novikov Iu A. 2011. Western blot as a confirming test in the laboratory diagnosis of syphilis. Klin. Lab. Diagn.:44-45. (In Russian.)